• 한국정보통신학회논문지
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• 제20권1호
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• pp.142-152
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• 2016

실내 측위 분야에서는 사용할 수 없는 GPS 의 한계를 극복하기 위해 대두되고 있는 기술들은 대부분 사설 무선 통신망(Private Wireless Network)를 이용한 방법이다. 그러나 이러한 방법들은 설치 및 유지 보수비용이 많이 들고 측위 오차가 수 미터로 실내 주차장 등 정밀한 측위가 필요한 장소에서 사용하기에 부적합하다. 본 논문에서는 QR 코드 인식 기반 차량용 실내 측위 방법을 제안하였다. QR 코드 스캔을 통해 절대 좌표를 얻고 아핀 변환(affine transform)을 통한 기울기(Tilt) 및 회전(Roll) 보정과 스케일 변환 및 삼각함수를 이용한 카메라의 위치 정보(상대좌표)를 획득하여 정밀한 위치 좌표를 계산한다. 결과적으로 13.79cm 의 평균 오차를 달성해 기존 무선 네트워크 기반 기술의 오차 50cm 대비 단지 27.6% 정도 오차율에 해당함을 확인하였다.

• 만화애니메이션 연구
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• 통권13호
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• pp.13-27
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• 2008

이 논문은 부천시 소재 한국만화영상산업진흥원의 구도 속으로 확장 이전하게 되는 한국만화박물관의 새로운 역할 모델에 관한 연구이다. 이를 위해 이제까지의 한국만화박물관 활동을 점검하고, 추후 만화박물관이 창작 진흥을 위한 시스템을 갖추면서 어떻게 만화산업 발전에 실질적인 기여를 할 수 있는지를 제안하였다. 무엇보다도 도시 브랜드적 가치나 산업 우위의 관점을 벗어나 박물관 본연의 활동에 충실하기 위한 여건 마련이 요구된다. 또한 한국만화의 우수성을 국제적 차원에서 알리기 위한 소장품 정책의 수립과, 해외 만화박물관 및 만화산업 관련 기구와의 네트워킹을 이루어낼 구조를 살려내는 일도 중요하다. 결과적으로 만화박물관은 새로운 활동 구조를 정비하되, 만화 창작 진흥을 중심으로 전시 기획과 작가 양성 프로그램을 실행하며, 이를 위해 독립 조직을 갖추어야 할 것이다.

• 수산해양기술연구
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• 제31권1호
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• pp.8-14
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• 1995

정치망 내외에 있어서 정어리 대형군의 행동조사는 1992년 1월 29일부터 2월 22일 사이에 일본국 석천현 칠미시 연안 정치망어장에서 소나를 이용하여 실시하였고, 소나의 영상기록을 해석하여 얻어진 결과를 요약하면 다음과 같다. 1. 정치망 바깥쪽 부근에서 이동중인 어군의 행동양식은 어군의 각 위치에 따라 다른 행동이 관찰되었고, 부분적인 확대와 축소를 보이면서 어군전체가 이동하였다. 2. 헛통입구로 들어간 어군은 등망방향, 헛통의 등방향, 헛통의 옆줄방향으로 분산되었으며, 그후 헛통의 등방향, 헛통의 옆줄방향, 입구방향의 어군은 등망쪽으로 조밀하게 이동하는 행동양식을 취하면서 입구로부터 외등망까지 이동하였다. 3. 정치망의 안쪽과 바깥쪽에 있어서 어군의 주연부가 확대하는 경우, 최대 이동속도는 바깥쪽에서 277cm/sec, 안쪽에서 176cm/sec이었다.

• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2001년도 춘계학술발표대회
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• pp.41-41
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• 2001

Chromatin configuration and microtubule assembly were determined in porcine maturing and activated oocytes following intracytoplasmic sperm injection. Microtubule localization was confirmed using a mouse monoclonal antibody to $\alpha$-tubulin and detected using a fluorescent labeled goat anti-mouse secondary antibody. DNA was stained with propidium iodide. The image of microtubules and chromatin was captured using laser scanning confocal microscope. In germinal vesicle stage oocyte, sperm chromatin remained condensation and sperm derived microtubules were not observed at 8 to 12 h after sperm injection. At 24 h after injection, the sperm nucleus developed to the metaphase chromatin along the metaphase structure of female nucleus. In some metaphase I stage oocytes, sperm chromatin decondensed at 8 h to 12 h after injection, sperm aster was seen soon after sperm injection. At 24 h after sperm injection into metaphase I stage oocyte, male chromatin developed to the metaphase chromatin while female chromatin extruded first polar body and formed the metaphase chromatin. At 12 to 15 h after sperm injection into preactivated oocytes, condensed sperm nucleus was located in close proximity of female pronucleus. However, the condensed nucleus did not fuse with female pronucleus. In preactivated ocytes, injected sperm remained condensation, a few sperm organized small microtubular aster. Instead, maternal derived microtubules were organized near the female chromatin, which seem to move condensed male chromatin near to the female pronucleus. These results suggest that sperm nuclear decondensing activity and nucleation activity of centrosome during fertilization are cell cycle dependent. In absence of male functional centrosome, female origin centrosome takes over the role of microtubule nucleation for nuclear movement.

• Journal of Yeungnam Medical Science
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• 제20권2호
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• pp.117-128
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• 2003

Thallium-201 scintigraphy is used to discriminate the malignant bone tumor from the benign by qualitatively and quantitatively, and to predict the response of preoperative chemotherapy in osteosarcoma, by comparing the changes of thallium uptake ratio after chemotherapy to the tumor necrosis ratio. Thallium-201 scintigraphy scan should be done prior to surgical biopsy. PICKER Prism 2000 gamma camera with high resolution parallel hole collimator is usually used for scanning. The patient is injected with 2-3mCi of Tl-201 and the early phase is checked in 30 minutes and delayed phase in 3 hours. The scan images are visually evaluated by a blinded nuclear medicine physician. We could evaluate true positive, true negative, false positive and false negative by the comparison of results with those of biopsy, and calculate positive and negative predictive value(%), sensitivity(%), specificity(%) and diagnostic accuracy(%). For the quantitative analysis of thallium uptake, we drew the region of interest on the tumor side and contralateral normal side as mirror image, and calculated the uptake ratio with dividing the amount of gamma count in tumor side by normal side. We could calculate the percent changes of thallium uptake ratio in early and delayed phase, and compare them to the ratio of tumor necrosis. Thallium-201 scintigraphy proved as useful imaging study to discriminate malignant bone tumor from benign, but had exception in giant cell tumor and low grade malignant bone tumors. We can use T1-201 scan to differentiate the benign from the malignant tumor, and to evaluate the response of preoperative chemotherapy or radiotherapy, and to determine the residual tumor or local recurrence. For the better result, we need to have a more detail information about false positive cases and a more objective and quantitative reading technique.

• Asian Pacific Journal of Cancer Prevention
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• 제15권1호
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• pp.161-166
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• 2014

Lung cancer is the most common causes of cancer-related deaths worldwide, and a lack of effective methods for early diagnosis has greatly impacted the prognosis and survival rates of the affected patients. Tumor-initiating cells (TICs) are considered to be largely responsible for tumor genesis, resistance to tumor therapy, metastasis, and recurrence. In addition to representing a good potential treatment target, TICs can provide clues for the early diagnosis of cancer. MicroRNA (miRNA) alterations are known to be involved in the initiation and progression of human cancer, and the detection of related miRNAs in TICs is an important strategy for lung cancer early diagnosis. As Hsa-miR-155 (miR-155) can be used as a diagnostic marker for non-small cell lung cancer (NSCLC), a smart molecular beacon of miR-155 was designed to image the expression of miR-155 in NSCLC cases. TICs expressing CD133 and CD338 were obtained from A549 cells by applying an immune magnetic bead isolation system, and miR-155 was detected using laser-scanning confocal microscopy. We found that intracellular miR-155 could be successfully detected using smart miR-155 molecular beacons. Expression was higher in TICs than in A549 cells, indicating that miR-155 may play an important role in regulating bio-behavior of TICs. As a non-invasive approach, molecular beacons could be implemented with molecular imaging to diagnose lung cancer at early stages.

• 한국임상수의학회지
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• 제34권5호
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• pp.318-324
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• 2017

The objective of this study was to establish kinematic reference ranges for the femorotibial (FT) joint and the patellofemoral (PF) joint in healthy small-breed dogs by measuring 3D kinematics at the walk. Single-plane fluoroscopy was used to image the stifle joints of five healthy beagle dogs while the dogs were walking. 3D bone models of the femur, patella, and tibia were reconstructed by computed tomography scanning of the beagle dogs' hind limbs. The shape-matching technique was used to measure kinematic data from the fluoroscopic images and the 3D bone models. The cranial translation of the tibia during walking was inversely proportional to the FT joint flexion. There were significant correlations between the patellar motion and the tibial motion. The FT joint flexion had a strong correlation with the patellar proximodistal translation and flexion. Additionally, the tibial mediolateral translation had a strong correlation with the patellar shift and tilt. In this study, normal in vivo 3D FT joint and PF joint kinematics were demonstrated, and the average kinematic parameters were determined in walking beagle dogs.

• 대한전자공학회논문지
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• 제26권7호
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• pp.83-89
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• 1989

강유전성 $PbTiO_3$ 박막을 rf스터링으로 기판온도 $100{\sim}150^{\circ}C$에서 형성시켰다. 이 박막의 구조는 X선 회절결과 비정질 형태로 파이로클로어 구조를 갖고 있었다. 이 박막을 열에 의해 어닐링한 경우는 $550^{\circ}C$에서, 레이저의 주사로 어닐링한 경우는 레이저 출력이 50watts일때 가장 우수한 결정 구조를 구할 수 있었다. 집합에서의 계면 특성을 구하기 위하여 MFS(metal-ferroelectric-semiconductor)및 MFOS(metal-ferroelectric-oxide-semiconductor) 구조를 형성하여 C-V특성을 조사하였다. 이때 MFS보다 MFOS의 경우가 Si표면에 sputter에 의한 결함이 작음을 알 수 있었다.

• The Journal of Advanced Prosthodontics
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• 제5권4호
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• pp.416-422
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• 2013

PURPOSE. This study was performed to define attachment and growth behavior of osteoblast-like cells and evaluate the gene expression on zirconia compared to titanium. MATERIALS AND METHODS. MC3T3-E1 cells were cultured on (1) titanium and (2) zirconia discs. The tetrazolium-based colorimetric assay (MTT test) was used for examining the attachment of cells. Cellular morphology was examined by scanning electron microscopy (SEM) and alkaline phosphatase (ALP) activity was measured to evaluate the cell differentiation rate. Mann-Whitney test was used to assess the significance level of the differences between the experimental groups. cDNA microarray was used for comparing the 20215 gene expressions on titanium and zirconia. RESULTS. From the MTT assay, there was no significant difference between titanium and zirconia (P>.05). From the SEM image, after 4 hours of culture, cells on both discs were triangular or elongated in shape with formation of filopodia. After 24 hours of culture, cells on both discs were more flattened and well spread compared to 4 hours of culture. From the ALP activity assay, the optical density of E1 cells on titanium was slightly higher than that of E1 cells on zirconia but there was no significant difference (P>.05). Most of the genes related to cell adhesion showed similar expression level between titanium and zirconia. CONCLUSION. Zirconia showed comparable biological responses of osteoblast-like cells to titanium for a short time during cell culture period. Most of the genes related to cell adhesion and signal showed similar expression level between titanium and zirconia.

• The Journal of Advanced Prosthodontics
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• 제9권5호
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• pp.358-363
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• 2017

PURPOSE. The purpose of this study was to evaluate the reliability of computer-aided replica technique (CART) by calculating its agreement with the replica technique (RT), using statistical agreement analysis. MATERIALS AND METHODS. A prepared metal die and a metal crown were fabricated. The gap between the restoration and abutment was replicated using silicone indicator paste (n = 25). Gap measurements differed in the control (RT) and experimental (CART) groups. In the RT group, the silicone replica was manually sectioned, and the marginal and occlusal gaps were measured using a microscope. In the CART group, the gap was digitized using optical scanning and image superimposition, and the gaps were measured using a software program. The agreement between the measurement techniques was evaluated by using the 95% Bland-Altman limits of agreement and concordance correlation coefficients (CCC). The least acceptable CCC was 0.90. RESULTS. The RT and CART groups showed linear association, with a strong positive correlation in gap measurements, but without significant differences. The 95% limits of agreement between the paired gap measurements were 3.84% and 7.08% of the mean. The lower 95% confidence limits of CCC were 0.9676 and 0.9188 for the marginal and occlusal gap measurements, respectively, and the values were greater than the allowed limit. CONCLUSION. The CART is a reliable digital approach for evaluating the fit accuracy of fixed dental prostheses.