• Journal of The Korean Dental Society of Anesthesiology
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• v.7 no.2
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• pp.120-125
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• 2007

Background: Propofol has been used extensively for short-acting intravenous sedative agent during monitored anesthesia care (MAC). This study was designed to evaluate the safety and availability of MAC using propofol in implant surgery of the one-day admission patients. Methods: In this study, subjects were divided into two groups according to ASA physical status. The heart rate, blood pressure, peripheral oxygen saturation and ECG of a patient were estimated under MAC by an anesthesiologist and the vital signs were recorded in recovery room periodically afterwards. The subjective satisfaction with regard to outpatient ambulatory surgery under MAC procedure was evaluated the next day. Results: Systolic and diastolic blood pressure were significantly decreased during MAC in ASA I group, but other remarkable changes in vital sign were not observed. There was no significant difference in pain and anxiety level between ASA I and ASA II, III group. Satisfaction rate was high in both groups. Conclusion: Monitored-Anesthesia Care using propofol during implant surgery of the one-day admission patients might be safe and available procedure because heart rate, blood pressure and oxygen saturation are stable before and during surgery, and adequate control of pain and anxiety is supported.

• Journal of Ginseng Research
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• v.36 no.4
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• pp.461-468
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• 2012

In this study, photosynthetic parameters such as the net photosynthesis rate, stomatal conductance, intercellular $CO_2$ concentration, and transpiration rate were examined in selected ginseng varieties and/or lines that are resistant (Yunpoong, HTIR 1, HTIR 2, and HTIR 3) and susceptible (Chunpoong) to high temperature injury (HTI). The net photosynthesis rate increased with the increase in the light intensity in all the HTI-resistant and -susceptible ginseng lines with a light saturation point of $200\;{\mu}mol\;m^{-2}s^{-1}$, except for Yunpoong that had a light saturation point of $400\;{\mu}mol\;m^{-2}s^{-1}$. At the light saturation point, the net photosynthesis rate in July was highest in HTIR 3, at $4.2\;{\mu}mol\;CO_2\;m^{-2}s^{-1}$, and was lowest in Yunpoong, HTIR 1, Chunpoong, and HTIR 2, in that order, at 1.9 to $3.7\;{\mu}mol\;CO_2\;m^{-2}s^{-1}$. The net photosynthesis rate in August was highest in Yunpoong at $5.9\;{\mu}mol\;CO_2\;m^{-2}s^{-1}$, and lowest in HTIR 1 and HTIR 3 ($4.5\;{\mu}mol\;CO_2\;m^{-2}s^{-1}$) and in other lines, in that order, at 2.8 to $2.9\;{\mu}mol\;CO_2\;m^{-2}s^{-1}$. The stomatal conductance in July was highest in HTIR 3 (0.055 mol $H_2O\;m^{-2}s^{-1}$) and Yunpoong, Chunpoong, HTIR 1, and HTIR 2 were 0.038, 0.037, 0.031, and 0.017 in that orders. In August, meanwhile, HTIR 1 showed the highest as 0.075, and followed by HTIR 3, Chungpoong, and HTIR 2 with 0.070, 0.047, and 0.023, respectively. The intercellular $CO_2$ concentration at the light saturation point in July and August was much lower in HTIR 2 at 139 and $185\;{\mu}mol\;mol^{-1}$ than in the other ginseng lines at 217 to 257 and 274 to $287\;{\mu}mol\;mol^{-1}$, respectively. The transpiration rate in July and August was higher in the HTI-resistant lines of Yunpoong, HTIR 1, and/or HTIR 3 at 0.83 to 1.03 and 1.67 to 2.10 mol $H_2O\;m^{-2}s^{-1}$ than in the other ginseng lines at 0.27 to 0.79 mol $H_2O\;m^{-2}s^{-1}$ and 0.51-1.65 mol $H_2O\;m^{-2}s^{-1}$, respectively. Conclusively, all the photosynthetic parameters that were examined in this study were generally higher in the HTI-resistant ginseng lines than in the HTI-susceptible lines, except for HTIR 2, and were much higher in August than in July, especially in the resistant ginseng lines. All these results can be used to provide basic information for the selection of HTI-resistant ginseng lines and the application of cultural practices that are efficient for ginseng growth, based on the photosynthetic characteristics of the lines.

• Journal of Life Science
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• v.8 no.5
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• pp.557-562
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• 1998

This study was conducted to investigate the influence of soil moisture on the photosynthetic rate, transpiration rate, stomatal conductance, leaf water content and its any correlation in soybean. Followings were achieved as a conclusion. At the soil moisture was moved from drought condition to saturation condition, the photosynthetic rate, transpiration rate, stomatal conductance and leaf water content were gradually increased on the period of re-watering treatment. The recovery of photosynthetic rate was faster than others. There were positive correlation with the photosynthetic rate and leaf water content, the stomatal conductance and leaf water content, the photosynthetic rate and stomatal conductance respectively, but the correlation coefficient of photosynthetic rate and leaf water content was high.

• Journal of Chest Surgery
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• v.13 no.2
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• pp.85-91
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• 1980

Extracorporeal circulation by hemodilution technique has been currently used with its clinical safety and good peripheral tissue perfusion in open heart surgery. There is no doubt that $O_{2}$ carrying capacity of the blood is disturbed by decreased hemoglobin level resulting from hemodilution of the circulating blood. From the view point of the blood gas exchange, these experimental studies were undertaken to determined the sate limit of hemodilution in the condition of cardiopulmonary bypass with a constant perfusion flow rate. Twelve adult mongrel dogs weighing 10 to 13 Kg. were anesthetized with pentobarbital and then respiration was controlled with Harvard volume respirator using room air. The cardiopulmonary by pass was performed by use of Sarns heart lung machine (console 5000, 5 head and 2 roller pumps) and Travenol pediatric bubble oxygenator. The perfusion rate during bypass was maintained at a constant rate of 80 ml/min/Kg of body weight. The ratio of oxygen gas flow to blood flow was kept in 3 to 1 constantly. International hemodilution was attained by serial blood withdrawals and immediate infusion of equal volumes of diluants composed of Ringer's lactate, 5% dextrose in water and 25% mannitol solution, proportionally 60%, 30%, and 10%. Arterial and venous blood samples were obtained between 15 and 20 minutes following each hemodilution. Hematocrits and hemoglobin values, $PO_{2}$, $PCO_{2}$ and pH were measured. Oxygen and carbon dioxide contents oxygen consumption and carbon dioxide elimination were calculated groups according to different hematocrit values and the correlations were evaluated. Result were as follows. 1. the arterial $O_{2}$ tension and $O_{2}$ saturation were maintained at the physiological level irrespective of the hematocrit value. 2. The venous $O_{2}$ tension and $O_{2}$ saturation showed a tendency to decline with the decrease in hematocrit value and positive correlation between them (r = +0.49, r = +0.76), The mean values of venous $O_{2}$ tension and $O_{2}$ saturation, however, were not decreased when the hematocrit levels were lower than 20%. 3. The arterial $O_{2}$ content declined lineally in proportion to the fall of hematocrit level with a positive correlation between them (r = +0.95). 4. The venous $O_{2}$ contents were decreased gradually as the hematocrit value decreased with positive correlation between them ( r =+0.89). The trend of diminution of venous $O_{2}$ content, however, was became low according to progressive decrease of hematocrit level. 5. Systemic oxygen consumption was in higher range than $O_{2}$ requirement of basal metabolism when the hematocrit value was above 20%, but abruptly decreased when the hematocrit value became to below 20%. 6. The arterial $CO_{2}$ tension and $CO_{2}$ content showed trend of increasing with progressive decrease of hematocrit value but exhibited a rather broad range and there was no relationship between those value and the hematocrit value. 7. The venous $CO_{2}$ tension and $CO_{2}$ content have also no correlation with change of Ht. value but related directly to those value of arterial blood with positive correlation between them (r = +0.78, r = +0.95_. 8. A-V difference of $CO_{2}$ content and $CO_{2}$ elimination wasnot significantly influenced by Ht. value. From the results, we obtained that feasible limit in inteneional hemodilution is above the hematocrit value of 20% under the given experimental condition.

• Journal of Korean Biological Nursing Science
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• v.3 no.2
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• pp.35-50
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• 2001

This study was conducted for the evaluation of the effects of singing program combined with physical exercise on the physiologic changes, perception function and degree of depression. The subjects were the members of elderly women's glee club in D care center for the elderly, who have been singing for more than 6 months. 30 members were allocated to study group and 30 to control group. The singing program designed for both physical therapy and music therapy was consisted of initial physical exercise, singing art songs and classical song and the finishing physical exercise. This program was performed twice a week and about forth minutes was consumed for one session. We checked the heart rate, peripheral arterial oxygen saturation, perception function and degree of depression before and after the program. We used a pulse oxymeter to check the heart rate to oxygen saturation and a questionnaire for the evaluation of perception function and degree of depression. We need SPSS program for data analysis. The results of the investigated personnel complying with general characteristics were analyzed by frequency, two groups by t-test, data before and after the program by paired t-test, respectively. The results were as follows. 1) Heart rate after the program was significantly lower than that before program in test group(p<0.05). 2) Peripheral oxygen saturation after the program was significantly higher than that before the program(p<0.05). 3) Ability to match the right sign with a certain predetermined number was improved after the program. The frequency of wrong matching the sign with number before program was 30. But the frequency was decreased to 8 after the program. 4) Ability to calculate was improved after the program. The frequency of wrong calculation before the program was $1.10{\pm}1.94$. But the frequency after the program was decreased to $0.97{\pm}1.84$. 5) The degree of depression after the program($2.07{\pm}0.49$) was significantly lower than that before program(p<0.001). These results show that singing program combined with physical exercise improves the oxygen delivery to peripheral circulation, stability of heart function, the perception function(calculating and matching ability) and decreases the degree of depression. In conclusion, singing program combined with physical exercise can be used for the effective measure to improve the health of elderly and prevent dementia.

• Journal of fish pathology
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• v.34 no.2
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• pp.213-224
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• 2021

Experiments were performed to investigate changes in metabolic rate (MO₂), critical oxygen saturation (S_crit) and hematological parameters of black rockfish, Sebastes schlegeli exposed to hypoxia at 15, 20 and 25℃. The MO₂ was measured at an interval of 10 min using intermittent-flow respirometry. The normoxic standard metabolic rate (SMR) was 116.5±5.5, 188.6±4.2 and 237.4±6.8 mg O₂/kg/hr, and S_crit was 22.1±1.2, 30.6±1.5 and 41.9±1.4% air saturation at 15, 20 and 25℃, respectively. Q₁₀ values were 2.62 between 15 and 20℃, 1.58 between 20 and 25℃, and 2.04 over the full temperature range. In the investigation of blood (hematocrit and hemoglobin) and biochemical parameters (plasma cortisol, glucose, electrolyte and osmolality), the rockfish were subjected to S_crit for each temperature during 4 hr. All of hematological parameters of the rockfish exposed to hypoxic water were significantly higher than those of normoxic control. Moreover, blood and biochemical parameters of the rockfish maintained to normoxic water showed the tendency of increase with temperature, and were significantly higher at 25C. As a result of this experiment, it was found that physiological stress due to hypoxia increased at high temperature.

• Nuclear Engineering and Technology
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• v.54 no.12
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• pp.4571-4584
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• 2022

The analysis of rapid flow transients in Reactor Coolant Pumps (RCP) is essential for a reactor safety study. An accurate and precise analysis of the RCP coastdown is necessary for the reactor design. The coastdown of RCP affects the coolant temperature and the colloidal crud in the primary coolant. A realistic and kinetic model has been used to investigate the behavior of activated colloidal crud in the primary coolant and steam generator that solves the pump speed analytically. The analytic solution of the non-dimensional flow rate has been determined by the energy ratio β. The kinetic energy of the coolant fluid and the kinetic energy stored in the rotating parts of a pump are two essential parameters in the form of β. Under normal operation, the pump's speed and moment of inertia are constant. However, in a coastdown situation, kinetic damping in the interval has been implemented. A dynamic model ACCP-SMART has been developed for System Integrated Modular and Advanced Reactor (SMART) to investigate the corrosion due to activated colloidal crud. The Fickian diffusion model has been implemented as the reference corrosion model for the constituent component of the primary loop of the SMART reactor. The activated colloidal crud activity in the primary coolant and steam generator of the SMART reactor has been studied for different equilibrium corrosion rates, linear increase in corrosion rate, and dynamic RCP coastdown situation energy ratio b. The coolant specific activity of SMART reactor equilibrium corrosion (4.0 mg s^-1) has been found 9.63×10^-3 µCi cm^-3, 3.53×10^-3 µC cm^-3, 2.39×10^-2 µC cm^-3, 8.10×10^-3 µC cm^-3, 6.77× 10^-3 µC cm^-3, 4.95×10^-4 µC cm^-3, 1.19×10^-3 µC cm^-3, and 7.87×10^-4 µC cm^-3 for ²⁴Na, ⁵⁴Mn, ⁵⁶Mn, ⁵⁹Fe, ⁵⁸Co, ⁶⁰Co, ⁹⁹Mo, and ⁵¹Cr which are 14.95%, 5.48%, 37.08%, 12.57%, 10.51%, 0.77%, 18.50%, and 0.12% respectively. For linear and exponential coastdown with a constant corrosion rate, the total coolant and steam generator activity approaches a higher saturation value than the normal values. The coolant and steam generator activity changes considerably with kinetic corrosion rate, equilibrium corrosion, growth of corrosion rate (ΔC/Δt), and RCP coastdown situations. The effect of the RCP coastdown on the specific activity of the steam generators is smeared by linearly rising corrosion rates, equilibrium corrosion, and rapid coasting down of the RCP. However, the time taken to reach the saturation activity is also influenced by the slope of corrosion rate, coastdown situation, equilibrium corrosion rate, and energy ratio β.

• Progress in Medical Physics
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• v.29 no.1
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• pp.29-41
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• 2018

The objective of this study was to evaluate the chemical exchange saturation transfer (CEST) effect of amino acids and neurotransmitters, which exist in the human brain, depending on the concentration, pH, and amplitude of the saturation radiofrequency field. Phantoms were developed with asparagine (Asn), ${\gamma}-aminobutyric$ acid (GABA), glutamate (Glu), glycine (Gly), and myoinositol (MI). Each chemical had three different concentrations of 10, 30, and 50 mM and three different pH values of 5.6, 6.2, and 7.4. Full Z-spectrum CEST images for each phantom were acquired with a continuous-wave radiofrequency (RF) saturation pulse with two different $B_1$ amplitudes of $2{\mu}T$ and $4{\mu}T$ using an animal 9.4T MRI system. A voxel-based CEST asymmetry was mapped to evaluate exchangeable protons based on amide (-NH), amine ($-NH_2$), and hydroxyl (-OH) groups for the five target molecules. For all target molecules, the CEST effect was increased with increasing concentration and B1 amplitude; however, the CEST effect with varying pH displayed a different trend depending on the characteristics of the molecule. On CEST asymmetric maps, Glu and MI were well visualized around 3.0 and 0.9 ppm, respectively, and were well separated macroscopically at a pH of 7.4. The exchange rates of Asn, Glu, BABA, and Gly usually decreased with increasing pH. The CEST effect was dependent on the concentration, acidity of the target molecules, and B1 amplitude of the saturation RF pulse. The CEST effect for Asn can be observed in a 9.4T MRI system. The results of this study are based on applying the CEST technique in patients with neurodegenerative diseases when proteins in the brain are increased with disease progression.

• Geosystem Engineering
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• v.21 no.6
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• pp.344-351
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• 2018

It is reported that the flooding rate in low permeability sandstones is low and the oil recovery is hard to increase after water breakthrough. Understanding characteristics of waterflood is hence important for the recovery improvement. In this work, flooding tests on low permeability sandstones were conducted. The corresponding flooding characteristics were investigated by means of CT scanning and Nuclear Magnetic Resonance. Effects of irreducible water and different rates were also discussed in detail. Experimental results reveal a piston-like displacement at a low rate in low permeability samples. The saturation profile is steep and almost vertical to the forward direction. The results at a low rate confirm that once water broke through, increasing the flooding rate or flooding time can hardly reduce the remaining oil inside the sample. It is probably due to the high pore-throat ratio proven by rate-controlled mercury. Results also confirm that the presence of initial water enhanced sweep efficiency substantially. On one hand, because water had previously occupied the small pores, the subsequent oil can only invade relatively large pores and became more movable. On the other hand, stable collars can not form due to the steep front, which may suppress the snap-off.

• Korean Journal of Optics and Photonics
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• v.8 no.4
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• pp.353-355
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• 1997

A single molecule detection system, which consists of confocal fluorescence microscope and single photon counter, has been used to observe the dye concentration dependence of photon counting rate. With increasing concentration, a saturation effect of counting is observed and demonstrated on the basis of the dead time of photon detector. The equations presented here show the relations between the counting rate and some parameters such as probe volume, quantum efficiency of detector, and fluorescence photon number entered onto detector. The signal-to-noise ratio is also discussed briefly.