• Title/Summary/Keyword: Saturation enhancement

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Comparative Bioreactor Studies in Terms of Oxygen Transfer between Suspended and Immobilized Fungal Systems for Cyclosporin A Fermentation (Cyclosporin A 생산을 위한 액체배양과 고정화배양의 생물반응기에서의 산소전달 비교 연구)

  • 전계택
    • KSBB Journal
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    • v.9 no.2
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    • pp.211-223
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    • 1994
  • In fermentations with a 4-liter stirred tank bioreactor, a better than two-fold enhancement of the gas-liquid mass transfer coefficient$(k_La)$ in the celite-immobilized fungal cultures of Tolypocladium in flatum over the parallel conventional free-cell was observed at identical biomass concentrations, despite the higher specific oxygen uptake rate of the immobilized fungi during exponential growth. As a result oxygen sufficient conditions, i. e., dissolve oxygen(D.O.) concentrations exceeding 75% air saturation, could be maintained throughout exponential growth period of the immobilized culture, in contrast to the suspended fungal culture, whose D.O. levels fell below 50% air saturation. A linear monotonic dependence of $k_La$ upon impeller agitaion rate was found for both immobilized and conventional cultivation modes over a range of 250 to 550rpm, the slope being a function of biomass concentration for the free but not for the immobilized cell system In contrasts oxygen transfer rate was a much weaker function of aeration rate up to about 2.5 vvm for both culture configurations. Above this level, aeration rate had no further effect on the mass transfer. In addition, the immobilized cultures sustained good morphological and physiological states, leading to almost two times higher cyclosporln A (CyA) productivity overt the parallel free cell system. These experiments suggest that the celite-immobilized fungal system in a stirred tank reactor has considerable promise for scaling up cyclosporin A production in terms of high-density cultivation.

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Nonlinearity Compensation of Electroabsorption Modulator by using Semiconductor Optical Amplifier (반도체 광증폭기를 이용한 전계흡수 광변조기 비선형성 보상)

  • Lee, Chang-Hyeon;Son, Seong-Il;Han, Sang-Guk
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.37 no.5
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    • pp.23-30
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    • 2000
  • To compensate the nonlinearity of electroabsorption modulator(EAM) resulting from its near exponential transfer function, a semiconductor optical amplifier(SOA) that has a log transfer function is used. Since the transfer function of SOA is inverse to that of EAM, the intermodulation distortion(IMD) of EAM can be reduced by cascading SOA to EAM. Also, the RF gain can be increased by the optical gain of SOA. For these reasons, spurious free dynamic range(SFDR) of EAM is enhanced by connecting SOA to EAM in series and operating in gain salutation region. To improve the nonlinearity compensation of EAM, the increased gain of SOA is required and the slope of gain saturation, the ratio of gain to input SOA power, needs to be steep. However, signal spontaneous beat noise that is the dominant system noise increases in proportion to the gain such that the SFDR of EAM is reduced. The higher the gain of SOA is, the more ASE is increased. Thus the noise level of system is increased and the following SFDR of EAM is decreased. The slope of gain saturation region and ASE of have trade-off relation and the optimization is achieved at 8㏈ optical gain. 9㏈ enhancement of SFDR of EAM is obtained. This scheme is easy to embody the linear EAM and the integration with three components (DFB-LD, EAM and SOA) offers many merits, such as low insertion loss, low chirping and low polarization sensitivity.

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Enhancement of Magneto-Optical Kerr Effect in Annealed Granular Films of Co-Au and $Co-AlO_x$

  • Abe, Masanori;Takeda, Eishi;Kitamoto, Yoshitaka;Shirasaki, Fumio;Todoroki, Norikazu;Gorodetzky, Gad;Ohnuma, Shigehiro;Masumoto, Tasuku;Inoue, Mitsuteru
    • The Korean Journal of Ceramics
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    • v.6 no.2
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    • pp.100-102
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    • 2000
  • Co fine particles were dispersed in Au metal and $AlO_x$ amorphous matrices by vacuum evaporation and rf-sputtering, respectively, thus forming granular composite films having chemical compositions of $Co_{0.59}-Au_{0.41}$ and $Co_{0.52}/(AlO_x$)_{0.48}$. The films were annealed at 200~$500^{\circ}C$ to increase the size of the Co particles, from 30$\AA$ to 180$\AA$ in the Au matrix and 40$\AA$ to 180$\AA$ in the $AlO_x$ matrix, as revealed by X-ray diffraction analysis. The Co metal in as-deposited films have saturation magnetization equivalent to that of bulk Co, which is unchanged by the annealing, showing that the Co metal is not oxidized by the annealing. Magneto-optical Kerr rotation measured at $\lambda$=400-900nm for the $Co_{0.59}-Au_{0.41}$ film as deposited is larger than that calculated for the composition. The rotation increases as the film is annealed at $200^{\circ}C$ and $300^{\circ}C$, approaching to that of bulk Co. The Kerr rotation for the $Co_{0.52}-(AlO_x)_{0.48}$ film as deposited is smaller than that calculated for the composition based on Bruggeman effective medium theory. However, the rotation increases much, exceeding the rotation of the bulk Co as annealed at $300^{\circ}C$ and $400^{\circ}C$. As a possible origin of the marked magneto-optical enhancement a weak localization of light in granular structure is suggested.

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Enhancement in the photocurrent of ZnO nanoparticles by thermal annealing

  • Byun, Kwang-Sub;Cho, Kyuong-Ah;Jun, Jin-Hyung;Seong, Ho-Jun;Kim, Sang-Sig
    • Journal of IKEEE
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    • v.13 no.1
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    • pp.57-64
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    • 2009
  • The optoelectrical characteristics of the ZnO nanoparticles (NPs) annealed in vacuum or oxygen condition from $200^{\circ}C$ to $600^{\circ}C$ were examined. Increased on-off ratio (or, the ratio of photocurrent to dark current) was observed when they were annealed at $300^{\circ}C$, $400^{\circ}C$ and $500^{\circ}C$ with the values enhanced about 4 orders compared to the as-prepared ZnO NPs in both annealing conditions, while the maximum efficiency was shown at the annealing temperature of $600^{\circ}C$ for the ZnO NPs annealed in vacuum with the value of 29.8 mA/W and at the temperature of $500^{\circ}C$ for those annealed in oxygen condition with the value of 40.3 mA/W. Photoresponse behavior of the ZnO NPs annealed in oxygen showed the sharp increase right after the ir exposure to the light followed by the slow decay and saturation during steady illumination, differing from the ZnO NPs annealed in vacuum which only exhibited the gradual increase. This difference occurred due to the curing effect of the oxygen vacancies. SEM images indicated no change in their morphologies with annealing, indicating the change in their internal structures by annealing, and most remarkably at $600^{\circ}C$. As for their photoluminescence(PL) spectra, the decrease of the deep-level(DL) emission was observed when they were annealed in oxygen at $400^{\circ}C$, and not at $200^{\circ}C$ and $600^{\circ}C$.

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External Condensation Heat Transfer Coefficients of R22 Alternative Refrigerants and R134a According to the Saturated Vapor Temperature Change on an Enhanced Tube (열전달 촉진관에서 R22 대체냉매 및 R134a의 포화증기 온도변화에 따른 외부 응축 열전달계수에 관한 연구)

  • Yoo Gil-Sang;Hwang Ji-Hwan;Park Ki-Jung;Jung Dongsoo
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.17 no.11
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    • pp.981-989
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    • 2005
  • In this study, external condensation heat transfer coefficients (HTCs) are measured on a low fin tube and Turbo-C tubes at the saturated vapor temperature of $30^{\circ}C$, $39^{\circ}C$, and $50^{\circ}C$ for R22, R410A, R407C and R134a with the wall subcooled at $3{\~}8^{\circ}C$. The HTCs of all refrigerants decreased as increasing the saturation temperature from $30^{\circ}C$ to $50^{\circ}C$. This trend is due to better thermodynamic properties of the liquid phase at low temperature Beatty and Katz's prediction yielded a $20.0\%$ deviation for the low fin tube data. The heat transfer enhancement factors for the 26 fpi low fin tube and Turbo-C tubes are 4.0${\~}$5.5 and 3.0${\~}$8.1 respectively for the refrigerants tested. Finally the performance of Turbo-C tube is better than that of the low fin tube.

Lipoprotein Lipase-Mediated Uptake of Glycated LDL

  • Koo, Bon-Sun;Lee, Duk-Soo;Yang, Jeong-Yeh;Kang, Mi-Kyung;Sohn, Hee-Sook;Park, Jin-Woo
    • BMB Reports
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    • v.33 no.2
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    • pp.148-154
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    • 2000
  • The glycation process plays an important role in accelerated atherosclerosis in diabetes, and the uptake of atherogenic lipoproteins by macrophage in the intima of the vessel wall leads to foam cell formation, an early sign of atherosclerosis. Besides the lipolytic action on the plasma triglyceride component, lipoprotein lipase (LPL) has been reported to enhance the cholesterol uptake by arterial wall cells. In this study, some properties of LPL-mediated low-density lipoprotein (LDL) uptake and the effect of LDL glycation were investigated in RAW 264.7 cell, a murine macrophage cell line. In the presence of LPL, $^{125}I$-LDL binding to RAW 264.7 cells was increased in a dose-dependent manner. At concentrations greater than $20\;{\mu}g/ml$ of LPL, LPL-mediated LDL binding was increased about 17-fold, achieving saturation. Without LPL, both very low-density lipoprotein (VLDL) and high-density lipoprotein (HDL) were ineffective in blocking the binding of $^{125}I$-LDL to Cells. However, LPL-enhanced LDL binding was inhibited about 50% by the presence of VLDL, while no significant effect was observed with HDL. Heat inactivation of LPL caused a 30% decrease of LDL binding. In the presence of LPL, the cells took up 40% of cell-bound native LDL. No significant difference was observed in cell binding between native and glycated LDL. However, the uptake of glycated LDL was significantly greater than that of native LDL, reaching to 70% of the total cell bound glycated LDL. These results indicate that LPL can cause the significant enhancement of LDL uptake by RAW 264.7 cells and the enhanced uptake of glycated LDL in the presence of LPL might play an important role in the accelerated atherogenesis in diabetic patients.

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Influence of Treatment Temperature on Surface Characteristics during Low Temperature Plasma Carburizing and DLC duplex treatment of AISI316L Stainless Steel (AISI316L 강에 저온 플라즈마침탄 및 DLC 복합 코팅처리 시 처리온도에 따른 표면특성평가)

  • Lee, In-Sup
    • Journal of Ocean Engineering and Technology
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    • v.25 no.6
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    • pp.60-65
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    • 2011
  • A low temperature plasma carburizing process was performed on AISI 316L austenitic stainless steel to achieve an enhancement of the surface hardness without degradation of its corrosion resistance. Attempts were made to investigate the influence of the processing temperatures on the surface hardened layer during low temperature plasma carburizing in order to obtain the optimum processing conditions. The expanded austenite (${\gamma}_c$) phase, which contains a high saturation of carbon (S phase), was formed on all of the treated surfaces. Precipitates of chromium carbides were detected in the hardened layer (C-enriched layer) only for the specimen treated at $550^{\circ}C$. The hardened layer thickness of ${\gamma}_c$ increased up to about $65{\mu}m$ with increasing treatment temperature. The surface hardness reached about 900 $HK_{0.05}$, which is about 4 times higher than that of the untreated sample (250 $HK_{0.05}$). A minor loss in corrosion resistance was observed for the specimens treated at temperatures of $300^{\circ}C{\sim}450^{\circ}C$ compared with untreated austenitic stainless steel. In particular, the precipitation of chromium carbides at $550^{\circ}C$ led to a significant decrease in the corrosion resistance. A diamond-like carbon (DLC) film coating was applied to improve the wear and friction properties of the S phase layer. The DLC film showed a low and stable friction coefficient value of about 0.1 compared with that of the carburized surface (about 0.45). The hardness and corrosion resistance of the S phase layer were further improved by the application of such a DLC film.

Bending ratcheting behavior of pressurized straight Z2CND18.12N stainless steel pipe

  • Wang, Lei;Chen, Gang;Zhu, Jianbei;Sun, Xiuhu;Mei, Yunhui;Ling, Xiang;Chen, Xu
    • Structural Engineering and Mechanics
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    • v.52 no.6
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    • pp.1135-1156
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    • 2014
  • The ratcheting effect greatly challenges the design of piping components. With the assistance of the quasi-three point bending apparatus, ratcheting and the ratcheting boundary of pressurized straight Z2CND18.12N stainless steel pipe under bending loading and vertical displacement control were studied experimentally. The characteristics of progressive inelastic deformation in axial and hoop directions of the Z2CND18.12N stainless steel pipes were investigated. The experiment results show that the ratcheting strain occurs mainly in the hoop direction while there is less ratcheting strain in the axial direction. The characteristics of the bending ratcheting behavior of the pressure pipes were derived and compared under load control and displacement control, respectively. The results show that the cyclic bending loading and the internal pressure affect the ratcheting behavior of the pressurized straight pipe significantly under load control. In the meantime, the ratcheting characteristics are also highly associated with the cyclic displacement and the internal pressure under displacement control. All these factors affect not only the saturation of the ratcheting strain but the ratcheting strain rate. A series of multi-step bending ratcheting experiments were conducted under both control modes. It was found that the hardening effect of Z2CND18.12N stainless steel pipe under previous cyclic loadings no matter with high or low displacement amplitudes is significant, and the prior loading histories greatly retard the ratcheting strain and its rate under subsequent loadings. Finally, the ratcheting boundaries of the pressurized straight Z2CND18.12N stainless steel pipe were determined and compared based on KTA/ASME, RCC-MR and the experimental results.

Thermal-Hydro-Mechanical Behaviors in the Engineered Barrier of a HLW Repository: Engineering-scale Validation Test (고준위폐기물처분장 공학적방벽의 열-수리-역학적 거동 연구: 엔지니어링 규모의 실증실험)

  • Lee, Jae-Owan;Cho, Won-Jin
    • Tunnel and Underground Space
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    • v.17 no.6
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    • pp.464-474
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    • 2007
  • An enhancement in the performance and safety of a high-level waste repository requires a validation of its engineered barrier. An engineering-scale test (named "KENTEX") has been conducted to investigate the thermal-hydro-mechanical behaviors in the engineered barrier of the Korean reference disposal system The validation test started on May 31, 2005 and is still under operation. The experimental data obtained allowed a preliminary and qualitative interpretation of the thermal-hydro-mechanical behaviors in the bentonite blocks. The temperature was higher as it became closer to the heater, while it became lower as it was farther away from the heater. The water content had a higher value in the part close to the hydration surface than that in the heater part. The relative humidity data suggested that a hydration of the bentonite blocks might occur by different drying-wetting processes, depending on their position. The total pressure was continuously increased by the evolution of the saturation front in the bentonite blocks and thereby the swelling pressure. Near the heater region, there was also a significant contribution of the thermal expansion of bentonite and the vapor pressure in the pores of the bentonite blocks.

Geomechanical Model Analysis for the Evaluation of Mechanical Stability of Unconsolidated Sediments during Gas Hydrate Development and Production (가스하이드레이트 개발생산과정에서의 미고결 퇴적층의 역학적 안정성 평가를 위한 지오메카닉스모델 해석)

  • Kim, Hyung-Mok;Rutqvist, Jonny
    • Tunnel and Underground Space
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    • v.24 no.2
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    • pp.143-154
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    • 2014
  • In this study, we simulated both dissociation of gas hydrate and mechanical deformation of hydrate-bearing sedimentary formation using geomechanical model. The geomechanical model analysis consists of two distinct codes of TOUGH+Hydrate and FLAC3D. The model is characterized by the fact that changes of temperature, pressure, saturation and their influence on the consequent evolution of effective stress, stiffness and strength of hydrate-bearing sediments during gas production could be well simulated. We compared the results of simulation for two different production methods, and showed that combination of depressurization and thermal stimulation results in the enhancement of production rate especially at early stage. We also presented that the hydrate dissociation-induced geomechanical deformation in unconsolidated clay is much larger than that in sandstone.