• Journal of Sasang Constitutional Medicine
• /
• v.28 no.2
• /
• pp.103-109
• /
• 2016

Objectives This paper investigates the origin, the progressive changes and the constructive principles of Jeoryoungchajeonja-tang(猪苓車前子湯).Methods Jeoryoungchajeonja-tang and other related prescriptions were analyzed in terms of their pathological indications, based on previous literature including 『Sanghannon(傷寒論)』, 『Keumkuaeyoryak(金匱要略)』, 『Donguibogam(東醫寶鑑)』, 『Donguisusebowon‧Sasangchobongwon(東醫壽世保元‧四象草本卷)』, 『Donguisusebowon‧Gabogubon(東醫壽世保元‧甲午舊本)』, 『Donguisusebowon‧Sinchukbon(東醫壽世保元‧辛丑本)』Results and Conclusions 1) The origin of Jeoryoungchajeonja-tang is discovered in the prescriptions for Lee-su(利水), that is, Jeoryoung-tang(猪苓湯). 2) Ohryoung-san(五苓散) introduced in 『Donguisusebowon‧Sasangchobongwon(東醫壽世保元‧四象草本卷)』progressively transformed into Shihosaryoung-san(柴胡四苓散)(『Donguisusebowon‧Gabogubon(東醫壽世保元 ‧甲午舊本)』) and ultimately into Jeoryoungchajeonja-tang(『Donguisusebowon‧Sinchukbon(東醫壽世保元‧辛丑本)』), a prescription appropriate for usage in the Mangeum symptomatology(亡陰證). 3) The Jeoryoungchajeonja-tang is composed of 10 herbs. Of these, Notopterygium incisum Ting(羌活), Aralia cordata Thunb.(獨活), Schizonepeta tenuifolia Briq.(荊芥), Saposhnikovia divaricata Schischk.(防風) make the Pyoeum(表陰) drop, and Anemarrhena asphodeloides Bge.(知母), Gypsum fibrosum(石膏) scatter the uihwa(胃火), and Poria cocos Wolf.(茯苓), Alisma canaliculatum(澤瀉), Polyporus umbellatus Fr.(猪苓), Plantago asiatica L.(車前子) facilitate urination.

• Journal of Korean Medicine for Obesity Research
• /
• v.7 no.2
• /
• pp.27-37
• /
• 2007

Background Clinical practice guidelines (CPG) are systematically developed statements to assist practitioners and patients on healthcare decisions. They provide recommendations for the average patient, which should take into account individual clinical judgment and the patient's values and expectations. Ephedra has sympathomimetic effect and has been used for weight loss worldwide. However, its safety is controversial especially in autonomic and cardiovascular systems. Therefore, the need of appropriate CPG for ephedra prescription in obesity was advocated in Korean Traditional Medicine. Methods The committee comprised of specialists of obesity, oriental herbology, oriental cardiology, constitutional medicine. The committee collected all relevant references about adverse effect and safety of ephedra in the forms of meta-analysis, systematic review, randomized controlled trial, case-control study and observational study from international and domestic databases and paper journals. 11 English- and 5 Korean-language references were gathered and categorized by PICO (Patient, Intervention, Comparison, Outcome) method. We could not complete strength of recommendation which should be clarified according to the evidence grade estimation. Result The first version of CPG for ephedra prescription in obesity was issued by Korean Oriental Association for Study of Obesity. It includes topics of introduction, pharmacokinetics, side effects and adverse events, constitutional aspect and recommendations for dose, indication and contraindication. Conclusion There should be periodic upgrade of this CPG from now on. Although there are some drawbacks in this version of CPG, it has significance as the first CPG in Korean Traditional Medicine.

• Journal of Sasang Constitutional Medicine
• /
• v.11 no.1
• /
• pp.201-220
• /
• 1999

We got these results after studying about modification of Gejitang(桂枝湯) that showed on sympton and prescription about Soumin(少陰人). 1. There are totally eleven prescriptions related to Gejitang appeared on Dongyi-Soose-Bowon(東醫壽世保元). Among them, one is prescription of Danguisayoktang(當歸四逆湯) in prescription of Discussion of Cold Induced Disorder(傷寒論) and another is Gejibujatang(桂枝附子湯) in Won-Myung dynasty period(元明時代). There are nine prescriptions in LeeJae-Ma(李濟馬)'s pre-scription and we can see there are many prescriptions used prescriptions related to Gejitang for Mang Yang(亡陽). 2. Pre-scriptions related to Gejitang has seven prescriptions in Extra-disease(表病證), and two prescriptions in Intra-disease(裏病證) which are analyzed as modified prescription from Gejitang. 3. Although 藿香正氣散, 香蘇散, 芎歸香蘇散, 八物君子湯 etc. are not modified prescriptions of Gejitang, We can see that its are brought up to be on the same with alternative remedy of Gejitang in each step of symptoms. 4. Symptoms are exactly classified in Soumin, the prescription which is used in different symptoms of diseases is similar in raw materials. It's because the remedy of Acending and Descending(升降) is used under the same purpose that maintain Yangnan Qi(陽暖之氣). 5. We could realize that Panax gienseng(人蔘), Cinnamomum Cassia(肉桂) and Aconitum Carrnichali(附子) are commonly important to reinforce Yangnan Qi because the more disease got worse, the more patient lost Yangnan Qi on both Extra-disease and Intra-disease in the Soumin's disease.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.14 no.1
• /
• pp.94-104
• /
• 2001

A Reports were done on 3 cases of proriasis, 1 case of chronic urticaria which were admition and treated by fasting therapy in Dept. surgery, opthalmology & otolaryngology, college of Oriental Medicine, Kyungsan University, Pohang, Korea, from March 1999 to October 2000. The results were as follows: 1. In the case chronic urticaria, symptom and sign(jtching, wheal, erythema), except of pigment, were showed conciderable improvement. 2. In the case proriasis, it is different of person, bellow 5cm sized erythematous popules were disappeared during fasting therapy, above 5cm sized erythematous papules and plaque were improved by using medication after fasting therapy. Silver-white colored scales was improved about $50-60\%$, itching was disappeared during fasting therapy. 3. After fasting therapy there was a recurrence, but about $40-50\%$ decreased symptoms were showed. 4. Besides upper diagnosis and treatment based on overall of symptoms and signs considered by documentary investigation, medications by Sasang prescription also can be expected good treatment effect.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.20 no.2
• /
• pp.312-319
• /
• 2006

Lee je-ma emphasis human constitution and write DongYeuSuSebowon(東醫壽世保元). He describe Sasang constitution diseases with Treatise on Febrile Diseases(傷寒論). Exogenous febrile disease(傷寒) is a pyrexia disease. Therefor this paper is focus on the pyrexia at Soyinin(少陰人) among DongYeuSuSebowon. Soyinin(少陰人) is consider that body water loss is more important than fever in pyrexia disease. And body water loss is happens easily at exothermic reaction (sweating, diarrhea) and sequela of Purgative Prescription(瀉下法), Inducing Diaphoresis(發汗法), Diuresis(利小便法).

• Herbal Formula Science
• /
• v.11 no.2
• /
• pp.1-18
• /
• 2003

The Theory for Monarch, Minister, Adjuvant and Dispatcher (or the Theory of Principal, Assistant, Adjuvant and Guiding Korean Oriental Herbal Medicines) has served as a standard principle for newly developed prescription formulas as well as established ones. Despite its significance, however, this theory hasn't been thoroughly studied and covered in the academic journals of Korean Oriental Herbal Medicines (KOHM) yet. This paper inquires into the origin of the theory while presenting the definitions and functions of Principal, Assistant, Adjuvant, and Guiding KOHM. In the end, the recommended doses and number of the KOHM comprising each of Principal, Assistant, Adjuvant, and Guiding KOHM are suggested. The compatibility theory of Principal, Assistant, Adjuvant, and Guiding KOHM can be traced back to the Warring States Period during which it was recorded in the treatise of the various schools of thoughts and their exponents. The theory was firmly established as a full system in ${\ulcorner}Shinnong's\;Pharmacopoeia{\lrcorner}\;and\;{\ulcorner}Yellow\;Emperor's\;Cannon\;of\;Internal\;Medicine{\lrcorner}$. While ${\ulcorner}Shinnong's\;Pharmacopoeia{\lrcorner}$ focuses on the classification of the properties of KOHM, ${\ulcorner}Yellow\;Emperor's\;Cannon\;of\;Internal\;Medicine{\lrcorner}$ mainly deals with the principles for writing prescriptions. In this regard, it is ${\ulcorner}Yellow\;Emperor's\;Cannon\;of\;Internal\;Medicine{\lrcorner}$ that systemized the Theory of Principal, Assistant, Adjuvant, and Guiding KOHM in a real sense. Principal KOHM aims at the causes of diseases and treat main symptoms. The doses are greater than Assistant, Adjuvant and Guiding KOHM. With their comprehensive effects, Principal KOHM is a leading ingredient of any prescription formula. Assistant KOHM are similar to Principal KOHM in its natures and flavors. Although its natures, flavors as well as efficacies may slightly differ from those of Principal KOHM, Assistant KOHM strengthens the therapeutic effects, jointly working with Principal KOHM. They mainly treat accompanying diseases and symptoms. Adjuvant KOHM is divided into two types: facilitator and inhibitor. Facilitators with the similar properties to those of Principal and Assistant KOHM help strengthen the therapeutic effects. Since they usually treat accompanying symptoms or secondary accompanying symptoms (minor accompanying symptoms), there are two kinds of facilitators. (1) The first kind of facilitators assists Principal KOHM, targeting accompanying symptoms. (2) The second ones supporting Assistant KOHM are for accompanying or secondary accompanying symptoms (or minor accompanying symptoms). Inhibitors counteract and thereby complement Principal and Assistant KOHM. Some of them inhibit the side effects or toxicity of Principal KOHM for the sake of the safety of the whole prescription formula while the others generate induced interactions. Guiding KOHM can be used for two purposes: guiding and mediating. The Guiding KOHM for the former purpose leads the other KOHM in a prescription formula to the lesion. But, the Guiding KOHM for mediating coodinate and harmonize all the ingredients in a prescription formula. The number of KOHM for those Principal, Assistant, Adjuvant and Guiding KOHM and their doses are different, depending on the types of prescriptions: classical prescriptions, prescriptions after ${\ulcorner}$Treatise of Cold-Induced Diseases${\lrcorner}$ and prescriptions of Sasang Constitutions Medicines. In the case of the prescriptions after ${\ulcorner}$Treatise of Cold-Induced Diseases${\lrcorner}$, it is highly recommended to follow the view of ${\ulcorner}$Thesaurus of Korean Oriental Medicine Doctors in Chosun Dynasty${\lrcorner}$ for the number of KOHM to be used. For the doses, however, ${\ulcorner}$Elementary Course for Medicine${\lrcorner}$, is found to be more accurate. The most appropriate number of KOHM per prescription is 11-13. To be more specific, for one prescription formula, it is recommended to administer one kind of KOHM for Principal KOHM, 2-3 for Assistant KOHM, 3-4 for Adjuvant KOHM and 5 for Guiding KOHM. As for the proportion of the doses, when 10 units are to be administered for Principal KOHM in a formula, the doses for the other three should be 7-8 units for Assistant KOHM, 5-6 for Adjuvant KOHM and 3-4 for Guiding KOHM. The doses of the KOHM added to or taken out of the prescription correspond to those of Adjuvant and Guiding KOHM.

• The Journal of Korean Medicine
• /
• v.41 no.3
• /
• pp.81-97
• /
• 2020

Objectives: The objective of this study is to review the methods of combining acupoints of HANGYEOK(Cooling Mode) and YEOLGYEOK(Heating Mode) in Saam Acupuncture Method. Methods: We searched and investigated the journals and literatures by OASIS(Korea Institute of Oriental Medicine) and relevant searching engines with the key word "Saam, Hangyeok, Yeolgyeok". Unfortunately there was no relevant articles on this theme except six literatures. Six literatures with the key words relevant to Saam and acupuncture were selected and analyzed according to each composition of acupuncture prescription especially focusing on HANGYEOK and YEOLGYEOK. Results: Analyzing HANGYEOK and YEOLGYEOK of 12 meridians, two different methods emerged. In HANGYEOK to treat Heat Pattern, one method is to tonify Water points and directly sedate Fire points. The other is also to tonify Water point, but sedate Earth points instead of Fire points. It is assumed that Earth sedation method is to eradicate the underlying Fire. In only Heart meridian and Pericardium meridian there is one method to treat Heat Pattern: Water tonification and Fire Sedation. In YEOLGYEOK to treat Cold Pattern, there is one method to tonify Fire points and sedate Water points. In Pericardium meridian and Triple Energizer meridian there are some different combination of acupoints depending on literatures. Conclusions: Considering HANGYEOK and YEOLGYEOK in Saam Acupuncture Method, two methods are mainly discussed in HANGYEOK; Water Tonification Fire Sedation and Water Tonification Earth Sedation. To remove the underlying Fire, it is regarded that Water Tonification Earth Sedation is appropriate and close to Saam's thought.

• Journal of Sasang Constitutional Medicine
• /
• v.9 no.1
• /
• pp.213-243
• /
• 1997

After studying about the formative process and theory concerning So-Yang In(少陽人)'s prescriptions, Some principles were founded. Those were summarized as follows. 1. Lee Jae Ma(李濟馬) established the theory and remedy about the So Yang In's diseases, and the formation of So Yang In's prescriptions was based on those theories and remedies 2. As the emprical prescription of So Yang In's diseases, ten pre-scriptions of Discussion of Cold-Induced Disorder(傷寒論) and nine of Won Myung dynasty period(元明時代) were described in Dong Eui Su-Se Bo Won(東醫壽世保元), and I could confirm that the formation of So Yang In's presciptions was based on those emprical prescriptions. 3. The pathological characteristics of emprical prescriptions of So-Yang In's diseases in Discussion of Cold-Induced Disorder(傷寒論) were completely corresponded with the principle of So Yang In's diseases, and we could know that emprical presciptions of diseases that were the base of So Yang In's prescriptions were selected by the principle of So Yang In's diseases. 4. In the serious cases of So Yang In's diseases, So Yang In's pre-scriptions were mostly made up of tonifying and nourishing yin medicine(補陰藥物) that dirrectly rufill the damaged Eum Chung Zi Ki(陰淸之氣). According to the above results, it could be concluded that Lee Jae-Ma(李濟馬) made So Yang In's prescriptions with emprical pre scri-ptions that were based on the theory of So Yang In's diseases and concluded that So Yang In's prescriptions were made up of tonifying and nourishing yin medicine(補陰藥物) in the serious cases of diseases.

• Journal of Sasang Constitutional Medicine
• /
• v.3 no.1
• /
• pp.201-217
• /
• 1991

In order to investigate experimental effects of Yangkyuksanwha-Tang, which is the typical prescription for diseased SOYANGIN, on diabetes rats, the observation and measurement was made on the content of volume of blood glucose, total cholesterol, triglyceride, phospholipid, total protein, electrolyte($K^+$, $Na^+$) in serum, by dosing the cooked Y.S.T. to diabetic rats, induced by streptozotocin and following result was obtained. 1. The volume of blood glucose, in the diabetes rats, was decreased significantly, and remarkable decrease of blood glucose was shown in the Y.S.T. (12.5ml/kg) dosed group, after 4weeks of experiment. 2. The volume of total cholesterol of blood serum was decreased notably, especially remarkable reduce of total cholesterol was shown in the Y.S.T. (12.5ml/kg) dosed group after a week. 3. The volume of triglyceride in the blood serum of diabetic rats, induced by the streptozotocin was decreased after 4 weeks, and remarkable decrease was shown in the Y.S.T. (12.5ml/kg) dosed group after 2 weeks of experiment. 4. The volume of the phospholipid in the diabetes rats, was decreased significantly in the Y.S.T. (12.5ml/kg) dosed group after 2 weeks of experiment. 5. The volume of total protein of diabetes rats, was increased in all group, and the remarkable increase was shown in the Y.S.T. (12.5ml/kg) dosed group after 4 weeks. 6. The volume of the sodium in the Y.S.T. (12.5ml/kg) dosed group, was notable in each Y.S.T. dosed group (1.25ml/kg, 12.5ml/kg) after a week experiment. According to above results, It is expected that Y.S.T. applied to SOYANGIN, can be used for medical treatment of diabetes with effect. But because the effect can be somewhat different depending upon dosage, appropriate operation on clinic is needed, for the best curing effect.

• The Journal of Korean Medicine
• /
• v.25 no.3
• /
• pp.169-179
• /
• 2004

Objectives : The purpose of this study is to research trends in the study of diabetes mellitus and to establish the future direction for its study. Methods : We reviewed oriental medicine papers published in the last twenty-three years(1980-2002). Results : 1. We researched 94 papers in 14 journals and the patterns of study were as follows: experimental studies were 53 (56.3%), reviewed studies were 20 (21.2%), clinical studies were 12 (12.7%) and case reports were 9 (9.8%). 2. The experimental studies (53) were divided into papers on efficiency testing of herbal medications (40) and acupuncture & moxibustion (13). 3. The reviewed studies showed that research has been carried out in the fields of cause, pathogenesis, principles for treating disease, acupuncture and moxibustion, herbal medication, exercise, and relation of sasang (사상) to diabetes mellitus. 4. The clinical studies showed that the research was carried out in the fields of follow up surveys for herbal medication efficiency testing, the relativity of diabetes mellitus to other diseases and sasang (사상). 5. In consequence of researching the case reports, there was no common prescription used meaningfully. Conclusions : We need more studies of diabetes mellitus by reaching for specific therapy.