• Journal of Sasang Constitutional Medicine
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• v.23 no.2
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• pp.218-229
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• 2011

1. Objectives: This study is to investigate the relationship between Intima Media Thickness(IMT) of common carotid artery and Sasang Constitution. 2. Methods: 839 persons, over 40 years old, participated in community-based cohort of Korea Genome and Epiedemiology Study (KOGES) in Wonju City and Pyeongchang City of South Korea from June 2006 to February 2008. The diagnosis of Common carotid Intima Media Thickness was evaluated by B Mode ultrasonography, cardiovascular risk factors were checked using questionnaire and blood samples. Constitution was verified by a Sasang constitution specialist according to the results of PSSC(Phonetic System for Sasang Constitution), facial photos and a simplified Sasang constitutional questionnaire. Multiple regression analysis and logistic regression analysis were performed with SPSS. 3. Results: There were significantly high values in waist circumference, fasting blood sugar, systolic blood pressure, diastolic blood pressure, triglyceride, HOMA-IR and hsCRP in Taeeumin and low in HDL-cholesterol and adiponectin in Taeeumin. There were significantly high value in Common Carotid Intima Media Thickness in Taeeumin. Age was the significant cardiovascular risk factor irrespective of Sasang constitution in all participants. There was a positive correlation between smoking and Soyangin in all participants and men. There were positive correlations between LDL-cholesterol, BMI and Taeeumin in all participants and men. There were positive correlations between hsCRP and Soeumin in all participants and men. There was significantly high odds ratio of Taeeumin over Soeumin in common carotid Intima Media Thickness. 4. Conclusions: Regimens on cardiovascular diseases should be considered according to Sasang constitution. There are more sensitive risk factor in each constitution; smoking in Soyangin, LDL-cholesterol and BMI in Taeeumin, hsCRP in Soeumin.

• Journal of Sasang Constitutional Medicine
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• v.13 no.2
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• pp.177-181
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• 2001

Sasang Constitutional Medicine is based on the diversity of Human being and medically developed the response variation to diseases and medicines. The diversity is categorized as four from physiology, pathology, symptoms, to therapy. So that is related the difference of individual characteristics in Western Science. Single nucleotide polymorphism is the basic tool to research genetic polymorphisms. We researched the polymorphism site of MTHFR gene on 1p36.3, which is relatively reported the occlusive vascular disease. In the clinical research of brain infarction, the occurrence was different according to constitution. The 677C/T Polymorphism site of MTHFR was not significantly different in constitution group. But this research was the first trial about the single nucleotide polymorphism according to constitution. The more researchs of many genes are necessary to find the characteristics of constitution.

• Journal of Sasang Constitutional Medicine
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• v.27 no.1
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• pp.138-148
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• 2015

Objectives This study was conducted in order to analyze the distribution of Sasang constitution, herbmed, exterior-interior disease and concomitant symptoms of 36 facial nerve paralysis patients. Methods A clinical study was done on 36 patients, treated as facial nerve paralysis. Sasang constitution specialist diagnosed their constitution and gave prescription. Degree of improvement was evaluated by assessment scale or change of patient's complaint. Results 1) Distribution of sasang constituion : Taeeumin 21 patients, Soyangin 8 patients, Soeumin 7 patients. 2) Distribution of exterior-interior disease : Taeeumin and Soeumin were diagnosed as interior disease more than exterior disease, Soyangin was reverse. 3) Hyeongbangdojeok-san and Hyeongbangjihwang-tang (Soyangin), Galgeunhaegi-tang(Taeeumin) and Gwakhyangjeonggi-san(Soeumin) were used the most in each sasang constitution. 4) Seventeen patients had concomitant symptoms : digestive disorder, sleep disorder, tinnitus, hypertension, diplopia, itching, gout, neck-shoulder pain, constipation and dizziness. Conclusions Patients had different Sasang constitution and in the same Sasang constitution, they had different symptomatology.

• Journal of Sasang Constitutional Medicine
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• v.19 no.3
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• pp.206-216
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• 2007

1. Objectives This Study recognize of the 17th Korean Assemblymen's Sasang Constitutional distribution and investigates Sasang Constitutional distribution of special group. 2. Methods The Questionnaire of Sasang Constitution was distributed to Korean Assemblymen's. The next, 2 persons of Sasang Constitutional Specialist interview directly, record of Korean Assemblymen's voice with PSSC and then concluded Sasang Constitution. 3. Results 1. After analysed Sasang Constitution with Questionnaire, We acquired zero person Taeyangin, sixteen persons Soyangin, nine persons Taeumin, zero person Soeumin. But, after direct interview examination, We acquired one person Taeyangin, seven persons Soyangin, twenty-two persons Taeumin, five persons Soeumin. 2. Soyangin rates was 20% practically, but Soyangin rates of amination with Questionnaire was 46%. Because Soyangin in Korean Assemblymen's expressed extrovert for oneself. 3. Taeumin constituted nineteen persons with Questionnaire, accounted for 54%. But Taeumin constituted twenty-two persons in direct interview examination, accounted for 63%. 4. Conclusions 1. In Uri Patty, Soyangin rates was 21%, Taeumin rates was 63%, Soeumin rates was 16%, Taeyangin rates was 0 %. The group of Taeyangin and Soyangin with activity and progression marked 21 %, the group of Taeumin and Soeumin with conservativeness marked 79%. 2. Grand National Parry, Soyangin rates was 14%, Taeumin rates was 64.3%, Soeumin rates was 14.3%, Taeyangin rates was 7.1 %. The group of Taeyangin and Soyangin with activity and progression marked 21.6%, the group of Taeumin and Soeumin with conservativeness marked 78.6%. 3. In comparison Uri Patty with Grand National Party, the rates of active Constitution marked 21.0% and 21.6% be much of a muchness. and in comparison Uri Parry with Grand National Parry, the rates of conservative Constitution marked 79.0% and 78.6% be much of a muchness.

• Journal of Sasang Constitutional Medicine
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• v.29 no.1
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• pp.21-28
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• 2017

Objectives The purpose of this study was to investigate of Quality of life and Mibyeong index of abnormal symptoms by Sasang constitution. Methods A total of 1,100 people were recruited into this study and were collected by Gallup Korea. Sasang constitutions were diagnosed based on KS-15 (Korean sasang constitutional diagnostic questionnaire) Questionnaire which comprised body type, personality and symptom. In addition, SF-12 (Shot form-12) questionnaire was used to evaluate the quality of life status. Mibyeong status was categorized through Mibyeong tool. Data were analyzed through one-way ANOVA to investigate the difference between quality of life and Mibyeong index on Sasang constitution. Results The PCS (physical component scale) which represents the physical health index and MCS (mental component scale) which represents mental health index showed significant differences among Sasang constitution (p<.001). In addition, The Mibyeong Index (p<.001) which represents abnormal symptom type showed significant difference for Sasang constitution. As for the Mibyeong, only pain (p=0.047) and fatigue (p=0.021) had changes for the Sasang constitution. Conclusions Quality of life and Mibyeong index vary significantly according to Sasang constitution. This results suggest the analysis of Mibyeong index by Sasang constitution could provide the setting of direction to promote public health depending on Sasang constitution.

• Journal of Sasang Constitutional Medicine
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• v.27 no.2
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• pp.288-296
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• 2015

Objectives Purpose of this study was to examine difference of taste score in herbal medicine among Sasang Constitution groups. Methods Seventy-three healthy students tasted salt solution, sucrose solution, four herbal medications (Hyangsayangwi-tang, Yanggyeoksanhwa-tang, Yeoldahanso-tang, and Mihudeungsikjang-tang), and then immediately scored intension of stimuli for each taste which they felt. Data of sixty-four final participant were analyzed by SPSS version 18, as follows: frequency analysis for characteristic data of participants, Kruskal-wallis test for difference in taste score among Sasang Constitution groups, and Pearson correlation analysis for the correlation between taste score of single taste stimuli and taste scores of herbal medications. Results Significant difference was shown in sweet taste score of Hyangsayangwi-tang among Sasang Constitution groups, that Soyangin showed higher sweet taste score of Hyangsayangwi-tang than Soeumin's. No significant difference was shown in other tastes or other herbal medications. Positive correlation between taste score of sucrose solution and sweet taste score of herbal medication was shown in Soemin. Conclusions There is difference in sweet taste score of Hyangsayangwi-tang among Sasang Constitution groups. There is positive correlation between sweet taste score of sucrose solution and herbal medication. This research has limitation, so well-designed research is needed.

• The Journal of Internal Korean Medicine
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• v.28 no.4
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• pp.791-796
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• 2007

Objective : This study was conducted to find the relationship between syndrome-differentiation and Sasang-constitution in chronic fatigue patients. Methods : The subjects were 72 adults with chronic fatigue who visited Dunsan Oriental Hospital of Daejeon University between March 2007 and April 2007. Their main complaint was fatigue for longer than 6 months and they did not have any physical or mental problems. We measured their fatigue degree by using Chalder fatigue scale and health habits. To evaluate relationship between syndrome-differentiation with sasang-constitution, The patients were divided into four syndrome-differentiations, such as liver and kidney asthenia of Yin, spleen and kidney deficiency of Yang, deficiency of lung and spleen qi, and deficiency of heart and spleen blood. We also diagnosed Sasang-constitution by using Questionnaire for Sasang Constitution Classification II (QSCCII). Results : Among the 72 patients, 41.4%, 34.5% and 24.1% of belonged in Soyangin, Soeumin and Taeumin respectively. Interestingly, we found a meaningful correlation between syndrome-differentiation and physiological function by Sasang-constitution. Conclusion : The result may help Oriental medicine understanding and treatment of chronic fatigue-related diseases and patients.

• Journal of Sasang Constitutional Medicine
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• v.16 no.3
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• pp.118-123
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• 2004

1. Objectives Yulkyuk is the interior syndrome of Taeyangin and it's chief symptom is dysphagia. Lee Je-Ma prescribed Mihudeungsikjang-tang for Taeyangin Yulkyuk. In this case we diagnosed a woman's chief complaints as Taeyangin Yulkyuk, prescribed Mihudeungsikjang-tang and experienced the effectiveness and reproduction of Mihudeungsikjang-tang against Yulkyuk. 2. Methods To treatment Taeyangin Yulkyuk we used Mihudeungsikjang-tang 3. Results Mihudeungsikjang-tang is effective against Taeyangin Yulkyuk and curled-up tongue, dry vomiting, dizziness are also the symptoms of Yulkyuk. 4. Conclusions We have many difficulties to diagnose and treatment Taeyangin constitution because there have been few clinical study about Taeyangin yet. Further study on Taeyangin constitution is more needed.

• Journal of Sasang Constitutional Medicine
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• v.17 no.1
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• pp.155-161
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• 2005

1. Objectives The purpose of this study was to investigate the effects of administration of Indongdeungjikolpi-tang on the Soyangin Jungso(中消). 2. Methods To heal the Soyangin Jungso, we used Indongdeungjikolpi-tang(忍冬藤地骨皮湯). 3. Results Jungso of a Soyangin patient responded well to the treatment with Indongdeungjikolpi-tang. 4. Conclusions This case-study shows an efficient results by using Indongdeungjikolpi-tang in treatment of Soyangin Jungso(Diabetes Mellitus).

• Journal of Sasang Constitutional Medicine
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• v.23 no.3
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• pp.361-373
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• 2011

1. Objectives: The purpose of this study was done to learn the Sasang constitutional distribution and to find out if there are differences in the type of diseases and symptoms according to the Sasang constitution in Japan. 2. Methods: We collected data from 366 patients who visited the Department of Oriental Medicine, Keio University and recruited 132 healthy persons in Tokyo, Japan. For sasang constitution diagnosis, they all have done SSCQ-P(Sasang Constitution Questionaire for Patients) questionnaire. and a sasang constitution specialist diagnosed the sasang constitution of them. And We classify the diseases and symptoms of 313 patients according to KCD(Korean Standard Classification of Diseases) and learn the prevalences of diseases and symptoms according to Sasang Constitution. 3. Results: 1) Among the total 498 subjects, distributional rate of Taeyangin, Soyangin, Taeeumin, and Soeumin were 2.0%, 26.3%, 29.9%, and 41.8%. Among the 366 patients, distributional rate of Taeyangin, Soyangin, Taeumin, and Soeumin were 0.8%, 27.3%, 28.7%, and 43.2%. Among the 132 healthy group, distributional rate of Taeyangin, Soyangin, Taeeumin, and Soeumin were 5.3%, 23.5%, 33.3%, and 37.9%. 2) The prevalences of 'V.Mental and behavioural disorders', 'XI.Diseases of the digestive system', 'XV.Pregnancy, childbirth and the puerperium' and 'feeling of coldness(X VIII.Symptoms, signs and abnormal clinical and laboratory findings, NEC)' of Soeumin were significantly higher than those of the other constitutions.(p-value<0.05) 4. Conclusions: The distributional rate of Sasangin of Japanese was different from that of Korean and especially the distributional rate of Soeumin of Japanese was significantly higher than that of Korean. There were significant differences on the prevalences of some diseases and symtoms according to KCD in Soeumin.