• 제3의학
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• 제2권1호
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• pp.25-33
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• 1997

In Sasang medicine, humen are classified into four constitutions which are Taeyang, Soyang. Taeum and Soum. Depending on each different constitution, the clinical and pharmacological application for the same disease might be different. In this study, genomic DNA of different constitutions(Taeum, Soyang and Soum) were analyzed by Restriction Fragment Length Polymorphism(RFLP) to provide scientific and objective references for Sasang classification. The DNA polymorphism for each constitution detected as differences in the length of DNA fragments, after digestion with restriction enzyme Hae III, was investigated using YNH24 as DNA probe. The allele size of Taeum, Soyang and Soum group detected by YNH24 ranged from 1.3 to 3.8 kb, 1.5 to 3.9 kb and 1.3 to 4.6 kb, respectively. However, the allele size distribution of YNH24 loci of different constitutions was shown to be too variable to be classified as 3 different constitution groups investigated. For further study, it is suggested that the number of each constitution samples for RFLP analysis should be increased and statistical analysis of the allele size distribution should be carried out.

• 사상체질의학회지
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• 제11권2호
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• pp.185-194
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• 1999

근래에 유전자를 이용하여 체질(體質)을 객관화하려는 시도가 있었다. 이에 본인은 그 동안 한의학계(韓醫學係)에서 이루어진 유전자를 이용한 사상체질(四象體質)의 객관화 연구와 의학계 쪽의 연구 중에서 어느 정도 연관성이 있는 논문들을 비교 검토하여 앞으로 사상의학(四象醫學)에서 유전자를 이용한 연구를 하는데 있어서 방향설정을 하는데 도움이 되고자 본 논문을 쓰게 되었다. 그 결과를 요약하면 다음과 같다. 1. 유전자 polymorphism(다형성)이 기능성을 가진 것을 대상으로 하여야한다. 2. Microsatellite는 기능을 가지지 않는 부분이므로 이것의 polymorphism이 체질(體質)과 관련될 가능성은 적을 것으로 사료된다. 3. Angiotensin converting enzyme (ACE)은 일반적으로 체질(體質)과 관련이 있다고 믿어지는 인내력(忍耐力)을 결정하는데 중요한 유전자로 알려져 있는 바 이 효소의 polymorphism을 이용하여 체질(體質)을 분류하고자 한 시도는 의미가 있는 것으로 생각된다. 4. HLA는 다형성을 가지고 있고 HLA유전자의 발현에 따라 질병에 대한 감수성이 차이가 있다는 사실을 고려해 볼 때 앞으로 이 분야는 연구해볼 충분한 가치가 있는 것으로 생각된다. 5. DNA chip의 사용이 보편화되면 사상체질(四象體質)의 객관화에 많은 도움이 될 것으로 생각된다.

• 사상체질의학회지
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• 제19권3호
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• pp.89-98
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• 2007

1. Objectives This study aims to evaluate newly developing Sasang Constitution Diagnosis Questionnaire for accuracy and efficiency. 2. Methods Three hundred and twenty eight patients from 4 multi centers are involved in this study. Excluding 16 constitution-unidentified patients and 2 Taeyang-in patients, 310 patients' questionnaires are analyzed statistically by their constitutions. 3. Results Sixty one questions are statistically significant in whole 229 questions of Sasang Constitution Diagnosis Questionnaire. We have selected 30 questions from 61 questions by comparing total data from 4 multi centers with those of each center. Thirty questions are made up of 10 body shape questions, 10 appearance questions, 5 character questions and 5 symptom questions. 3. Conclusions There might be needs for revision of character and symptom questions. From results, we suggest to diagnose Sasang Constitution for screening by short-form questionnaire consisted of questions on body shapes and appearances.

• 대한암한의학회지
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• 제13권1호
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• pp.25-32
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• 2008

1. Objective This study was conducted to research a corelation between the Sasang constitutions and primary cancer organs in cancer patient with their thermography. 2. Method We Analyzed the thermography taken from cancer patients and compared it with their cancer origins and Sasang constitution. 3. Result It was found that there are some relationships between the cancer origins and abnormal skin temperature. Also according to the Sasang constitutions of each cancer patient, the lesion of abnormal skin temperature could be differentiated. 4. Conclusion Thermogram can be affected by both the constitution and the primary cancer organs of the patient. To utilize the thermography as a diagnostic or prognostic method of cancer, further studies are needed.

• 동의신경정신과학회지
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• 제16권2호
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• pp.65-72
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• 2005

Objectives : This study is for discovering the clinical Features of the sleep in ordinary symptoms based on the Sasang Constitution. The result of this study could be helpful to understand and to identify the patients as Soyangin in contrast with the other constitutions -Soeumin, Taeumin and Taeyangin. Methods : There were 1,229 patients(700 female), who answered the questionnaire about their ordinary sleeping patterns. They had been diagnosed, including their clinical Sasang Constitution, by the Sasang Constitution specialist at Bundang Oriental Hospital of Dongguk University. By applying the binary logistic regression analysis, we can measure the characteristics and the influence of ordinary sleeping patterns to the dependent variable(Sasang Constitution). Results : As a result of the binary logistic analysis on the observed questionnaire, we found the characteristics of the ordinary sleeping patterns on Soyangin in contrast with the other constitutions. Firstly, Soyangin has a tendency that he wouldn't dreams more, when he sleeps in contrast with the others. Secondly, Soyangin has a tendency that he wouldn't sleep longer than 6-7hours. Thirthly, Soyangin has a tendency that he will sleep well in contrast with the others. Conclusion : This study will be used to identify patients as Soyangin in contrast with the others-Soemin, Taeumin and Taeyangin.

• 사상체질의학회지
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• 제20권2호
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• pp.43-52
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• 2008

1. Objectives This study aims to find out the factors that affect to healthy level according to Sasang Constitutions by comparing THI health state with Sasang Health Index. 2. Methods One hundred twenty one healthy students from Korean oriental medical colleges participated in this study. We used the Questionnaire for Sasang Constitution Classification II(QSCC II) and expert opinion to diagnose Sasang Constitution, and used Sasang Health Index and THI questionnaire to take health information about Sasang Constitution, from 121 people of Sasang Constitution Information Bank. 3. Results 1) The 'Good Sweat' in Taeumin health level was higher than others, especially in case of 'Refreshness after Sweat' and the 'Good Feces' also higher in case of 'Much Volume in Defecation' 'Regularity in Defecation' 'Refreshness after Evacuation'. 2) The 'Good Feces' in Soyangin health level was higher than others, especially in case of 'Thickness'. 3) The 'Good Digestion' in Soeumin health level was not significantly higher than others. 4) The better symptoms in 'Good Sweat', the better health in Taeumin. 4. Conclusions Sasang Constitution Health Level is significantly related with Sasang Health Index.

• 동의생리병리학회지
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• 제25권6호
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• pp.1079-1084
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• 2011

The purpose of this study is to evaluate the association between the results such as height, weight, body index mass, laboratory values, drinking, smoking habit which is performed in Health examination and Sasang constitution. From this, we want to suggest the objective standard for discriminating Sasang constitutions. The subjects of this study were 1,570 college freshmen for which QSCCII were surveyed to discriminate of Sasang constitution. All the data were analysed by descriptive statistics and chi-square test for explanation of interesting variables. We used logistic regression model to extract significant factors for discriminating Taeeumin from Soeumin, Soyangin from Taeeumin, Soeumin from Soyangin and to get each odds ratio. Taeeumin group showed significantly higher AST, TG, LDL, BUN, Creatinine level and lower HDL level. And Taeeumin group also showed the hightest value of BMI ($24.8{\pm}3.65\;kg/m^2$). And according to logistic regression analysis, BMI and Weight were the most effective factors for discriminating each constitution groups. From the above results, we have to consider BMI as an objective standard for discriminating Sasang constitutions.

• 사상체질의학회지
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• 제25권4호
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• pp.330-342
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• 2013

Objectives This study was to examine the differences on alexithymia, rumination, depression and somatic symptoms by each Sasang constitution, and aimed at combining the psychological construct with Korean medical treatment. Methods One hundred eighty men and women aged from 20 to 69 who reside in Geoje-si were selected, and data from 173 people consisting of the three constitutions-Soyangin(39), Taeeumin(83), and Soeumin(51), excepted the minority sample of Taeyangin(7 people)-were analyzed. Collected data were analyzed and tested by IBM SPSS Statistics 20: frequency analysis for demographic data; t-test for gender differences; one-way ANOVA for differences among three constitutions; and Pearson correlation analysis for the correlation between variables. Results The result of t-test taken for the gender differences between variables was not significant. According to the result of one-way ANOVA conducted by different Sasang constitutions, no variables showed a significant result except that of alexithymia. The correlation analysis showed that the alexithymia had positive correlation with rumination, depression, and somatic symptoms. Rumination was in positive correlation with depression and somatic symptoms. Especially, depression had high positive correlation with somatization symptoms. Among the variables analyzed by each constitution, only the survey result of the alexithymia was significant. Conclusions Given that each constitution showed different levels of the alexithymia, it can be concluded that therapeutic intervention in the treatment for the Taeeumin who shows a high level of alexithymia is needed to improve their emotional recognition and expression. In this context, application of program which focus on the emotional ability such as emotion coaching to the Korean medical treatment is expected to improve alexithymia, depression, and somatic symptoms.

• 척추신경추나의학회지
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• 제3권2호
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• pp.69-76
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• 2008

Objectives : The purpose of this study is to investigate the relationship among low back pain, lumbar lordosis, obesity and Sasang constitution. Methods : The researcher discriminated the Sasang constitutions of those observed-the inpatient-who were treated from March to May 2008 for low back pain. X-ray were taken in lateral decubitus and the lumbar lordotic angles(LLA) were measured. BMI were measured. This results were statistically analyzed using SPSS 12.0. Results : 1. Among the 31 subjects, distributional rate of Soyangin, Taeumin, and Soeumin were 48.4%, 29.0% and 22.6%. 2. The result showed a significant difference with the Sasang constitution from $\ll$Dongy Suse Bowqn$\gg$. 3. The result showed a difference with the Sasang constitution from the existing result from OSCC II. 4. There was no significant relations between each constitutions and lumbar lordotic angle. 5. There was significant relations between each constitutions and BMI. Conclusions : In this study, The rate of Soyangin, among the low back pain patients, was higher. And the average of BMI was higher in Taeumin.

• 동의생리병리학회지
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• 제26권6호
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• pp.964-969
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• 2012

This study aimed to evaluate the relationship between the results of blood test and Sasang constitution. We performed blood test of 2,387 university students in Health examination. Sasang constitution was diagnosed by using the Questionnaire of Sasang Constitution Class II(QSCC II). All the data were analysed statistically by descriptive statistics, ANOVA and logistic regression analysis. The Taeeumin group showed significantly higher AST, ALT, GGT, LDH, CPK, creatinine, uric acid, total cholesterol, TG, and LDL levels than other groups, while having a lower HDL level. According to logistic regression analysis, Hb, RBC, uric acid, creatinine were effective common factors for classifying each constitution groups. In the results of this study, there were significant differences in the results of blood test between the three constitutions. But the blood test was insufficient as an objective indicator for discriminating Sasang constitutions.