• Title/Summary/Keyword: Sarcoma

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Metastatic Clear Cell Sarcoma of the Kidney in a Child's Hand Bone - A Case Report - (소아의 수부골에 전이된 신장의 투명세포육종 -1례 보고-)

  • Shim, Jong-Sup;Kim, Jee-Hyoung;Suh, Yeon-Lim
    • The Journal of the Korean bone and joint tumor society
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    • v.4 no.2
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    • pp.94-98
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    • 1998
  • Clear cell sarcoma of the kidney (CCSK) is a rare malignant tumor of the renal origin in childhood, distinguished from Wilms tumor by its pathologic and clinical features. Bone metastasis is one of the characteristic clinical features. The common site of metastasis of the clear cell Sarcoma of the kidney is axial skeleton including skull, spines, ribs and femur. A cases of clear cell Sarcoma of the kidney presented to us, which solely metastasized to the hand bones without metastasizing to any other tissues including axial skeleton. We report this case with review of literatures.

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Antitumorigenic Effects of Tannin From Persimmon Leaves on Sarcoma 180-induced Tumor in Mice

  • Moon, Sung-Chai;Park, Kyong-Hee;Rhew, Tae-Hyong;Park, Kun-Young;Kim, Byeong-Gee
    • Preventive Nutrition and Food Science
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    • v.3 no.1
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    • pp.92-97
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    • 1998
  • The changes of morphology and protein pattern of sarcoma 180 cells treated with or without trannins extracted from persimmon leaves were evaluated by light microscopy, electrophoresis and Western blotting. The sarcoma 180 cells treated with tannins increased the amount of proteins which presumably were intermediate filament cytokeratins detected by electrophoresis and Western blot. Tannins was indirectly cytotoxic to the sarcoma 180 cells and increased the intermediate filament protein level in the cells.

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A Case Report of Cutaneous Low-grade Myofibroblastic Sarcoma in the Neck (경부 피부에서 발생한 저등급 근섬유모세포 육종 증례 보고)

  • Hannara, Park;Junhyun, Lim;Hyochun, Park;Hyeonjung, Yeo
    • Korean Journal of Head & Neck Oncology
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    • v.38 no.2
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    • pp.15-18
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    • 2022
  • Myofibroblastic sarcoma can be classified as low-, intermediate-, and high-grade. Low-grade myofibroblastic sarcoma (LGMS) is uncommon and rarely appears on the skin. LGMS is diagnosed based on histopathological and immunohistochemical findings. Additionally, LGMS metastases are rare as well. Herein, the authors describe a case of cutaneous LGMS in the neck. To the best of our knowledge, there are no cases regarding cutaneous LGMS in the neck present in the existing literature. Surgical resection is considered as the most important treatment for LGMS. Therefore, a complete tumor resection was performed in this case. However, another mass in the uterus was identified on abdominal computed tomography performed post-surgery.

Ewing's Sarcoma of the Stomach; Rare Case of Ewing's Sarcoma and Suggestion of New Treatment Strategy

  • Kim, Hyo-Sin;Kim, Sungsoo;Min, Young-Don;Kee, Keun-Hong;Hong, Ran
    • Journal of Gastric Cancer
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    • v.12 no.4
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    • pp.258-261
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    • 2012
  • Ewing's sarcoma is a neoplasm of the undifferenciated small round cells, which generally affects the bone and deep soft tissues of children and adolescents. We present a case of gastric Ewing's sarcoma; a 35-year-old female who had no symptoms. While she was at a routine medical checkup, a protruding mass in her gastric antrum was incidentally found on esophagogastroduodenoscopy. Endoscopic ultrasonogram showed a submucosal mass on the same lesion and a laparosopic wedge resection was done. Pathologic gross findings showed a granular grape appearance tissue and histoloigc examination revealed a small round cell tumor with CD 99 immunoexpression positive. In general, a combined modality therapy for Ewing's sarcoma such as surgical resection with chemotherapy, is accepted as an effective method. However, this patient had no adjuvant chemotherapy after surgery and she has no recurrence for eleven months.

Experimental Study of Naesosan(內消散) on the Effects of Anti-Cancer (內消散의 抗癌效果에 관한 實驗的 硏究)

  • Park, Su-Yeon;Choe, Jeong-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.14 no.1
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    • pp.154-166
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    • 2001
  • Naesosan(NSS) has been used in Oriental Medicine as a drug that treated carbuncle and cellulitis. So, the purpose of this Study was to investigate effects of NSS on the cytotoxicity of cancer cell lines and lymphocytes in vitro, proliferation of Ll210 cells and lymphocytes in L1210 cells transplanted mice, improvement of blood count in Ll210 cells transplanted mice, tumor weight and body weight in sarcoma-180 cells transplanted mice, survival prolongation in sarcoma-180 cells transplanted mice. We used NSS extract with freeze-dried, 8wks-old male mice(balb/c and ICR mouse $18{\pm}2g$). Ll210 cell lines, and sarcoma-180 cell lines for this Study, The proliferation of cells was tested using a colorimetric tetrazoliun assay(MTT assay). The results of this Study were obtained as follows ; 1. NSS showed significantly cytotoxicitic effects of cancer cell lines, did not show cytotoxicitic effects of lymphocytes. 2, Proliferation of lymphocytes in L1210 cells transplanted mice did not effects by NSS. 3. NSS inhibited significantly the proliferation of L1210 cells in L1210 cells transplanted mice. 4. NSS improved significantly the blood count in Ll210 cells transplanted mice. 5. NSS increased significantly th body weight in sarcoma-180 cells transplanted mice. 6. NSS dereased significantly the tumor weight in sarcoma-180 cells transplanted mice. 7. NSS prolonged significantly the survival time in sarcoma-180 cells transplanted mice.

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Cardiac Autotransplantation with Concurrent Pneumonectomy for Complete Resection of Primary Cardiac Intimal Sarcoma

  • Ku, Min Jung;Kim, Su Wan;Lee, Seogjae;Chang, Jee Won;Lee, Jonggeun;Jeong, Dong Seop
    • Journal of Chest Surgery
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    • v.53 no.3
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    • pp.140-143
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    • 2020
  • Primary cardiac sarcoma is rare, and intimal sarcoma is an extremely rare and highly lethal disease. We report a case of a 62-year-old woman who was incidentally diagnosed with a primary cardiac sarcoma originating from the left atrial appendage and extending to the left superior pulmonary vein. The location of the tumor was very complicated, posing a major challenge for complete resection. We successfully performed complete resection of the cardiac sarcoma via cardiac autotransplantation with left pneumonectomy. The patient recovered uneventfully, without any adjuvant therapy as of 6 months postoperatively. Autotransplantation of the heart may be suggested as a reasonable surgical option for extensive left atrial tumors.

Low Grade Myofibroblastic Sarcoma of the Sternocleidomastoid Muscle (흉쇄유돌근에서 기인한 Low-Grade Myofibroblastic Sarcoma 1예)

  • Sim, Nam Suk;Hong, Hyun Jun;Song, Kee-Jae;Choi, Sung-Eun;Suh, Yun Suk;Lee, Eun Jung
    • Korean Journal of Head & Neck Oncology
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    • v.30 no.1
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    • pp.23-27
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    • 2014
  • Low-grade myofibroblastic sarcoma is a rare disorder of malignant soft tissue tumor and is usually occurred various regions that often manifests in the head and neck region. The most common clinical presentation of this entity is non-tender cervical lymphadenopathy. This disease usually presents high possibility of local recurrence and low possibility of distant metastasis. We report a rare case of low-grade myofibroblastic sarcoma occurring in the sternocleidomastoid muscle and invading to the mastoid tip. A 56-year-old male visited the clinic with a complaint of slowly growing postauricular mass for 6 months. Mass originating from sternomastoid muscle and invasion to mastoid tip was observed by imaging studies. Surgical complete excision with simple mastoidectomy was performed via modified facelift approach. The histopathologic findings revealed malignant spindle cell tumor with positive staining with smooth muscle actin. The patient has no recurrence for 2years without any complication.

Antitumor Effect of Persimmon Leaves in vivo using Sarcoma-180 Cells (Sarcoma-180 세포를 이용한 in vivo에서 감잎의 항암효과)

  • 문숙희;김광혁;박건영
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.5
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    • pp.865-870
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    • 1996
  • Antitumor effects of hexane, chloroform fractions and tannins from persimmon leaves were studied by using sarcoma-180 tumor cells. The solid tumor growth was inhibited most effectively when 0.5mg/kg of hexane fraction was administerated to the Balb/c mouse. The life prolongation effects were 35.6%, 11.5% and 29.9%, respectively when hexane fraction, chloroform fraction and tannins from the persimmon leaves were administerated to the mouse. Spleen index, a marker for immunological activity, was increased in mice administrated hexane fraction, chloroform fraction and tannins of persimmon loaves, compared with the control group.

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Synovial Sarcoma of the Anterior Chest Wall: A Case Report (앞가슴벽에 생긴 윤활막육종: 증례 보고)

  • Mingook Kim;Seung Eun Lee;Joon Hyuk Choi
    • Journal of the Korean Society of Radiology
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    • v.81 no.5
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    • pp.1227-1233
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    • 2020
  • Synovial sarcoma is a malignant soft tissue tumor that usually involves the extremities, particularly near the knees; a synovial sarcoma originating in the chest wall is extremely rare. We describe a 26-year-old woman diagnosed with a synovial sarcoma originating in the chest wall, based on CT and MRI findings. Contrast-enhanced CT images revealed a small, well-defined enhancing mass with calcification, in the subpleural area. This lesion was initially diagnosed as a benign tumor; however, the patient developed sudden severe pain with spontaneous bleeding and hemothorax, suggesting the possibility of malignancy. MRI revealed a multilobulated mass with a fluid-fluid level, which characterizes a synovial sarcoma.

An Ethmoid Sinus Ewing Sarcoma with Exophthalmos in A 21-Year-Old Male (안구 돌출을 주소로 내원한 21세 남환에서 사골동 유잉 육종 1예)

  • Young Rok Jo;Youn Jin Cho;Ju Yeon Pyo;So Yeon Yoon;Keejae Song
    • Korean Journal of Head & Neck Oncology
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    • v.39 no.2
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    • pp.55-58
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    • 2023
  • Ewing sarcoma is a rare tumor in head and neck area. We demonstrate a rare case of sinonasal Ewing sarcoma initially suspected as olfactory neuroblastoma. After the surgery and immunohistochemical studies, it was accurately diagnosed as Ewing sarcoma. We would like to emphasize the possibility that Ewing sarcoma may originate from the head and neck area, and hence, it is important to use appropriate techniques for accurate diagnosis and treatment.