• Title/Summary/Keyword: Sampling error

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Stability Analysis of a Haptic System with a Human Impedance model using the Routh-Hurwitz Criterion (루드-후르비쯔 (Routh-Hurwitz) 안정성 판별법을 이용한 인간의 임피던스가 포함된 햅틱 시스템의 안정성 분석)

  • Lee, Kyungno
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.4
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    • pp.1813-1818
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    • 2014
  • This paper presents the stability analysis of the haptic system including a human impedance using the Routh-Hurwitz criterion. The reflective force is computed from a virtual spring model and is transferred to a human operator using the first-order-hold method. The stability boundary conditions are induced and the relation among a virtual spring ($K_w$), the mass ($M_h$), the damping ($B_h$) and the stiffness ($K_h$) of a human impedance is analyzed. Hence the stability boundary of the virtual spring ($K_w$) is proposed as $K_w{\leq}54413{\sqrt{(M_h+M_d)(B_h+B_d)}}-0.486K_h$ when the sampling time is 1 ms. The average relative error is about 0.5% when the mathematical analysis results are compared with the results of the stability boundary model.

A New Cancer Cell Detection Method Using an Infectivity-enhanced Adenoviral Vector

  • Uchino, Junji;Takayama, Koichi;Nakagaki, Noriaki;Shuo, Wang;Hisasue, Junko;Nakatom, Keita;Ohta, Keiichi;Hirano, Ryosuke;Tashiro, Naoki;Miiru, Izumi;Fujita, Masaki;Watanabe, Kentaro;Nakanishi, Yoichi
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5551-5556
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    • 2012
  • Cytological examination is widely used as a diagnostic tool because of the ease of collecting cells from the involved area. However, the diagnostic yield of cytological examination is unsatisfactory; the reasons include sampling error, poorly prepared samples, small numbers of malignant cells, and low grades of cellular atypia. In this study, we focused on the high infectivity of adenovirus towards epithelial cells and applied the luciferase-expressing adenoviral vector to a new cancer cell detection tool. In addition, adenoviral infectivity was enhanced by modifying viral fiber proteins. The sensitivity of the diagnostic tool was tested using the NCI-H1299 lung cancer cell line, and validated in body fluid samples from cancer patients with a variety of etiology. Results showed that the adenovirus efficiently transfected NCI-H1299 with high sensitivity. Only 10 cancer cells were sufficient for detection of luciferase signals. In body fluid samples, the adenovirus confirmed the diagnosis for malignant and benign cancer, but not in non-epithelial cell derived samples. This study provides proof-of-concept for a more reliable and sensitive diagnostic tool for epithelium-derived cancer.

A Study on the Optimal Aggregation Interval for Travel Time Estimation on the Rural Arterial Interrupted Traffic flow (지방부 간선도로 단속류 통행시간 추정을 위한 적정 집락간격 결정에 관한 연구)

  • Lim Houng-Seak;Lee Seung-Hwan;Lee Hyun-Jae
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.3 no.2 s.5
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    • pp.129-140
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    • 2004
  • In this paper, we conduct the research about optimal aggregation interval of travel time data on interrupted traffic flow and verify the reliability of AVI collected data by using car plate matching method in RTMS for systematic collection and analysis of link travel time data on interrupted traffic flow rural arterial. We perform Kolmosorov-Smirnov test on AVT collected sample data and on entire population data, and conclude that the sample data does not represent pure random sampling and hence includes sample collection error. We suggest that additional review is necessary to investigate the effectiveness of AVI collected sample data as link representative data. We also develop statistical model by applying two estimation techniques namely point estimation and interval estimation for calculating optimal aggregation interval. We have implemented our model and determine that point estimate is preferable over interval estimate for exactly selecting and deciding optimal aggregation interval. Our final conclusion is that 5-minute aggregation interval is optimal to estimate travel time in RTMS, as is currently being used our investigation is based on AVI data collected from Yang-ji to Yong-in $42^{nd}$ National road.

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Derivation of a benchmark dose lower bound of lead for attention deficit hyperactivity disorder using a longitudinal data set (경시적 자료의 주의력 결핍 과잉행동 장애를 종점으로 한 납의 벤치마크 용량 하한 도출)

  • Lee, Juhyung;Kim, Si Yeon;Ha, Mina;Kwon, Hojang;Kim, Byung Soo
    • The Korean Journal of Applied Statistics
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    • v.29 no.7
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    • pp.1295-1309
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    • 2016
  • This paper is to reproduce the result of Kim et al. (2014) by deriving a benchmark dose lower bound (BMDL) of lead based on the 2005 cohort data set of Children's Health and Environmental Research (CHEER) data set. The ADHD rating scales in the 2005 cohort were not consistent along the three follow-ups since two different ADHD rating scales were used in the cohort. We first unified the ADHD rating scales in the 2005 cohort by deriving a conversion formula using a penalized linear spline. We then constructed two linear mixed models for the 2005 cohort which reflected the longitudinal characteristics of the data set. The first model introduced the random intercept and the random slope terms and the second model assumed the first order autoregressive structure of the error term. Using these two models, we derived the BMDLs of lead and reconfirmed the "regression to the mean" nature of the ADHD score discovered by Kim et al. (2014). We also noticed that there was a definite difference between the sampling distributions of the two cohorts. As a result, taking this difference into account, we were able to obtain the consistent result with Kim et al. (2014).

Neutron Activation Analysis of Human Hair for Human Health Assessment (인체보건 환경평가를 위한 모발의 중성자방사화분석)

  • Chung, Young-Sam;Kang, Sang-Hoon;Moon, Jong-Hwa;Kang, Young Hwan;Cho, Seung-Yon
    • Analytical Science and Technology
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    • v.14 no.2
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    • pp.131-139
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    • 2001
  • There is personal difference in the concentrations of trace elements in human hair according to human life or history suck as occupation, race, sex, age, food habit, social condition and so on. It is also found that the individual's deviation of elemental concentrations is reflecting the degree of environmental pollutants exposure to human body, intakes of food and metabolism. To compare the degree of accumulation in the hair tissue, human hair samples were collected from five positions of head and analyzed by non-destructive neutron activation analysis with and without washing according to IAEA's recommended method. Analytical quality control is performed using the certified reference material. The relative error of Cu, Cr, Na, Co, Mg, As, Se, Zn and those of Mn, Ca, Fe, Sr are within ${\pm}5%$ and ${\pm}10%$, respectively and the relative standard deviation of elements are within ${\pm}10%$. The deviations between the individuals and hair sampling positions were estimated. The deviation of individual was seven times more than that of positions. Under the defined condition, the difference and the correlation of elemental concentrations were compared with two different groups, office and factory workers. The result can be used as a fundamental data for human health and environment assessment.

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A Study on the Long-run Equilibrium Relationship and Causality between the Prices of Fisheries Products at Different Levels of Distribution -Focused on Hairtail and Squid in Pusan- (수산물의 유통단계별 가격간 장기균형관계와 인과성 분석 -부산지역의 갈치, 오징어를 중심으로-)

  • 강석규;이광진
    • The Journal of Fisheries Business Administration
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    • v.29 no.2
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    • pp.77-96
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    • 1998
  • Fisheries products in Korea generally go through three markets, namely the wholesale market at production site (Market A), the wholesale market at consumption site (Market B), and the retail market (Market C), from producers to end consumers. As the products move from Market A through Market B to Market C, the marginal gap of prices asked in these markets demonstrates an apparent relationship. The producers, middlemen, consumers, and governmental departments concerned may influence the marketing prices of fisheries products. This study employing the cointegration theory tries to investigate whether causality of the price-setting among these markets exists and, if any, what it is. The authors have focused their attention on fisheries markets in Pusan, analyzing the long-run equilibrium relationship and causality between the prices of hairtail and squid among markets at different levels. Data used in this study cover the period f개m August 1984 to December 1997 fer hairtail, and the period from May 1989 to December 1997 for squid. The main findings of the study may be summarized as follows: First, regardless of the price time-series of hairtail and squid in individual market, the first difference is necessary fur satisfying the stationary conditions since each time-series is a first integration. This means homogeneous integration of time-series, which is a requirement of the long-run equilibrium of prices at different markets, is satisfied. Second, the study of the long-run equilibrium relationship between the prices at Market A and Market B shows that a long-run equilibrium relationship does exist for selling prices of the two species at Market A and Market B. Third, the ECM (error correction model ) used here to describe the long- and short-run dynamics of price change demonstrates that, in the case of squid, the price change in Market A will lead to a corresponding price change in Market B in the long-run period. In the short-run, however, the price at Market H is not only influenced by the price change in Market A but influence the price at Market A as well, that is, the Prices between Market A and Market B have a feedback effect. It should be stressed that the limitation in data collection, which cover only two species of hairtail and squid, is likely to cause a sampling bias. Nonetheless, we may conclude that a dynamic relation in the formation of prices does exist in view of the transaction amount of species at different markets. It is believed that the conclusion drawn from this study would not only contribute to a long-lasted debate on the direction of causality of price-setting among academic circle and fishing community, but would provide a useful standard for the policy makers in charge of the price-setting of fisheries products as well.

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Analysis of Manganese Nodule Abundance in KODOS Area (KODOS 지역의 망간단괴 부존률 분포해석)

  • Jung, Moon Young;Kim, In Kee;Sung, Won Mo;Kang, Jung Keuk
    • Economic and Environmental Geology
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    • v.28 no.3
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    • pp.199-211
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    • 1995
  • The deep sea camera system could render it possible to obtain the detailed information of the nodule distribution, but difficult to estimate nodule abundance quantitatively. In order to estimate nodule abundance quantitatively from deep seabed photographs, the nodule abundance equation was derived from the box core data obtained in KODOS area(long.: $154^{\circ}{\sim}151^{\circ}W$, lat.: $9^{\circ}{\sim}12^{\circ}N$) during two survey cruises carried out in 1989 and 1990. The regression equation derived by considering extent of burial of nodule to Handa's equation compensates for the abundance error attributable to partial burial of some nodules by sediments. An average long axis and average extent of burial of nodules in photographed area are determined according to the surface textures of nodules, and nodule coverage is calculated by the image analysis method. Average nodule abundance estimated from seabed photographs by using the equation is approximately 92% of the actual average abundance in KODOS area. The measured sampling points by box core or free fall grab are in general very sparse and hence nodule abundance distribution should be interpolated and extrapolated from measured data to uncharacterized areas. The another goal of this study is to depict continuous distribution of nodule abundance in KODOS area by using PC-version of geostatistical model in which several stages are systematically proceeded. Geostatistics was used to analyse spatial structure and distribution of regionalized variable(nodule abundance) within sets of real data. In order to investigate the spatial structure of nodule abundance in KODOS area, experimental variograms were calculated and fitted to a spherical models in isotropy and anisotropy, respectively. The spherical structure models were used to map out distribution of the nodule abundance for isotropic and anisotropic models by using the kriging method. The result from anisotropic model is much more reliable than one of isotropic model. Distribution map of nodule abundance produced by PC-version of geostatistical model indicates that approximately 40% of KODOS area is considered to be promising area(nodule abundance > $5kg/m^2$) for mining in case of anisotropy.

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Construction and Experiment of an Educational Radar System (교육용 레이다 시스템의 제작 및 실험)

  • Ji, Younghun;Lee, Hoonyol
    • Korean Journal of Remote Sensing
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    • v.30 no.2
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    • pp.293-302
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    • 2014
  • Radar systems are used in remote sensing mainly as space-borne, airborne and ground-based Synthetic Aperture Radar (SAR), scatterometer and Doppler radar. Those systems are composed of expensive equipments and require expertise and professional skills for operation. Because of the limitation in getting experiences of the radar and SAR systems and its operations in ordinary universities and institutions, it is difficult to learn and exercise essential principles of radar hardware which are essential to understand and develop new application fields. To overcome those difficulties, in this paper, we present the construction and experiment of a low-cost educational radar system based on the blueprints of the MIT Cantenna system. The radar system was operated in three modes. Firstly, the velocity of moving cars was measured in Doppler radar mode. Secondly, the range of two moving targets were measured in radar mode with range resolution. Lastly, 2D images were constructed in GB-SAR mode to enhance the azimuth resolution. Additionally, we simulated the SAR raw data to compare Deramp-FFT and ${\omega}-k$ algorithms and to analyze the effect of antenna positional error for SAR focusing. We expect the system can be further developed into a light-weight SAR system onboard a unmanned aerial vehicle by improving the system with higher sampling frequency, I/Q acquisition, and more stable circuit design.

Application of 10Be Dating Technique for Marine Terrace Studies and Its Limitations (해안단구 연구를 위한 10Be 연대측정법의 적용과 한계점)

  • Shin, Jae-Ryul
    • Journal of the Korean earth science society
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    • v.36 no.6
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    • pp.512-519
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    • 2015
  • Although Quaternary marine terraces and onshore paleo-shoreline records provide clues to our understanding for the mode and nature of neotectonics in the Korean peninsula, it cannot be accomplished without knowledge on both independent information of the past sea level records and tectonic deformation field together with precise results of numerical dating for higher terraces. This study reported cosmogenic radionuclides ($^{10}Be$) dating results conducted in higher terraces in the eastern and western coasts of the Korean peninsula. As a result, the measured concentration ratio of $^9Be/^{10}Be$ and the exposure ages were much younger than expected. It implies that either there is possibility of error in experimental processes or the samples experienced a complex exposure history probably included a burial at some stage. Considering the past climatic conditions around the Korean peninsula and a possible complex exposure history after the emergence of marine terrace, the discovery of a suitable study area and a sampling site are an essential part of successful $^{10}Be$ dating technique.

Design of Digital PLL with Asymmetry Compensator in High Speed DVD Systems (고속 DVD 시스템에서 비대칭 신호 보정기와 결합한 Digital PLL 설계)

  • 김판수;고석준;최형진;이정현
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.26 no.12A
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    • pp.2000-2011
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    • 2001
  • In this Paper, we convert conventional low speed(1x, 6x) DVD systems designed by analog PLL(Phase Locked Loop) into digital PLL to operate at high speed systems flexibly, and present optimal DPLL model in high speed(20x) DVD systems. Especially, we focused on the design of DPLL that can overcome channel effects such as bulk delay, sampling clock frequency offset and asymmetry phenomenon in high speed DVD systems. First, the modified Early-Late timing error detector as digital timing recovery scheme is proposed. And the four-sampled compensation algorithm using zero crossing point as asymmetry compensator is designed to achieve high speed operation and strong reliability. We show that the proposed timing recovery algorithm provides enhanced performances in jitter valiance and SNR margin by 4 times and 3dB respectively. Also, the new four-sampled zero crossing asymmetry compensation algorithm provides 34% improvement of jitter performance, 50% reduction of compensation time and 2.0dB gain of SNR compared with other algorithms. Finally, the proposed systems combined with asymmetry compensator and DPLL are shown to provide improved performance of about 0.4dB, 2dB over the existing schemes by BER evaluation.

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