• Title/Summary/Keyword: Sample array

Search Result 204, Processing Time 0.029 seconds

A Frequency-dependent Single Cell Impedance Analysis Chip for Applications to Cancer Cell and Normal Cell Discrimination (주파수에 따른 단일세포의 임피던스 분석칩 및 암세포와 정상세포의 구별에의 적용)

  • Chang, YoonHee;Kim, Min-Ji;Cho, Young-Ho
    • The Transactions of The Korean Institute of Electrical Engineers
    • /
    • v.63 no.12
    • /
    • pp.1671-1674
    • /
    • 2014
  • This paper presents a frequency-dependent cell impedance analysis chip for use in cancer and normal cell discrimination. The previous cell impedance analysis chips for flowing cells cannot allow enough time for cell-to-electrode contact to monitor frequency-dependent impedance response. Another type of the previous cell impedance analysis chips for the cells clamped by membranes need complex sample control for making stable cell-to-electrode contact. We present a new impedance analysis chip using the microchamber array, on which a PDMS cover is placed to make stable cell-to-electrode contact for the individual cell trapped in each microchamber; thus achieving frequency-dependent single-cell impedance analysis without complex sample control. Compared to the normal cells, the magnitude of NHBE cells is $60.07{\sim}97.41k{\Omega}$ higher than A549 cells in the frequency range of 95.6 kHz~2MHz and the phase of NHBE is $3.96^{\circ}{\sim}20.8^{\circ}$ higher than A549 cells in the frequency range of 4.37 kHz~2MHz, respectively. It is demonstrated experimentally that the impedance analysis chip performs frequency-dependent cell impedance analysis by making stable cell-to-electrode contact with simple sample control; thereby applicable to the normal cell and cancer cell discrimination.

Effect of LED light on the inactivation of Bacillus cereus for extending shelf-life of extruded rice cake and simulation of the patterns of LED irradiation by various arrays of LEDs (압출떡의 유통기한 연장을 위한 LED 조사의 Bacillus cereus 억제 효과 및 LED의 배열에 따른 빛의 조사 패턴 시뮬레이션)

  • Jung, Hwabin;Yuk, Hyun-Gyun;Yoon, Won Byong
    • Journal of Applied Biological Chemistry
    • /
    • v.62 no.2
    • /
    • pp.181-186
    • /
    • 2019
  • The optimum design of LED device for irradiation of 460 nm blue light on extruded rice cake using simulation and the effect of the blue light on the inactivation of Bacillus cereus (B. cereus) group on the rice cake were investigated. The irradiated light intensity patterns on the surface area of the sample were simulated with three different LED arrays (centered, cross, and evenly spaced) and at various distances (22, 32, 42 mm) between the LED modules and the sample. In addition, the uniformity was calculated as Petri factor. The evenly spaced array resulted the most uniform light intensity pattern in the simulation, and the Petri factor of 32 and 42 mm of the distances showed higher than 0.9, which represents the ideal uniformity of LED device. The bacterial population of the rice cake decreased to less than the initial bacterial population during exposure to LED blue light, whereas the bacterial population of the control sample increased. The bacterial count of the rice cake after blue light irradiation for 24 h was 1.21 log CFU/g lower than the control sample. Petri factor increased with increase of the distance between the light source and sample, however, the reduction rate of B. cereus group decreased. Therefore, the design of LED device, that represented the Petri factor higher than 0.9 and inactivated the population of B. cereus group, with evenly spaced and 32 mm of distance between the light source and sample was suitable for extending shelf-life of rice cake.

A Low-Power 2-Step 8-bit 10-MHz CMOS A/D Converter (저전력 2-Step 8-bit 10-MHz CMOS A/D 변환기)

  • 박창선;손주호;김영랄;김동용
    • Proceedings of the IEEK Conference
    • /
    • 2000.06b
    • /
    • pp.201-204
    • /
    • 2000
  • In this paper, an A/D converter is implemented to obtain 8bit resolution at a conversion rate of 10Msample/s. This architecture is proposed using the 2-step architecture for high speed conversion rate. It is consisted of sample/hold circuit, low power comparator, voltage reference circuit and DAC of binary weighted capacitor array. Proposed A/D converter is designed using 0.2$\mu\textrm{m}$ CMOS technology. The SNR is 45.3dB at a sampling rate of 10MHz with 1.95MHz sine input signal. When an 8bit 10Msample/s A/D converter is simulated, the Differential Nonlinearity / Integral Nonlinearity (DNL/ INL) error are ${\pm}$1 / ${\pm}$2 LSB, respectively. The power consumption is 13㎽ at single +2.5V supply voltage.

  • PDF

Position Estimation Using Magnetic Field Map (자기장 지도를 이용한 위치 추정)

  • Kim, Han-Sol;Moon, Woo-Sung;Seo, Woo-Jin;Baek, Kwang-Ryul
    • Journal of Institute of Control, Robotics and Systems
    • /
    • v.19 no.4
    • /
    • pp.290-298
    • /
    • 2013
  • Geomagnetic is refracted by building's wall and pillar. Therefore refracted geomagnetic is able to be used as feature point. In a specific space, a mobile device that is equipped with magnetic sensor array measures 3-axis magnetic field for each point. Magnetic field map is acquired by collecting the every sample point in the magnetic field. The measured magnetic field must be calibrated, because each magnetic sensor has a distortion. For this reason, sensor distortion model and sensor calibration method are proposed in this paper. Magnetic field that is measured by mobile device matches magnetic field map. Result of the matching is used for position estimation. This paper implements hardware system for position estimation method using magnetic field map.

FPGA Implementation and Experiment of a Time-Delayed Controller for Humanoid Robot Arm Control (다관절 휴머노이드 로봇 팔의 제어를 위한 시간지연 제어기의 FPGA 구현 및 실험)

  • Lee, Woon-Kyu;Jeon, Hyo-Won;Jung, Seul
    • Journal of Institute of Control, Robotics and Systems
    • /
    • v.13 no.7
    • /
    • pp.649-655
    • /
    • 2007
  • In this paper, a time-delayed controller for position control of humanoid robot arms is designed and implemented on a field programmable gate array(FPGA) chip. The time-delayed control algorithm is simple to implement, and robust to reject disturbances. The time-delayed control method uses the one sample time-delayed previous information to cancel out uncertainties in the system. Since the sampling time is so fast with the current hardware technology, the time-delayed controller can be implemented. However, inertia values should be correctly estimated to have the better performance. The position tracking tasks of humanoid robot arms are tested to compare performances of several control algorithms including the time-delayed controller.

A 8-bit 10-MHz CMOS A/D Converter (8-bit 10-MHz CMOS A/D 변환기)

  • 박창선;손주호;이준호;김종민;김동용
    • Proceedings of the IEEK Conference
    • /
    • 1999.11a
    • /
    • pp.263-266
    • /
    • 1999
  • In this work, a A/D converter is implemented to obtain 8bit resolution at a conversion rate of 10MS/s for video applications. This architecture is proposed using the Pipelined architecture for high speed conversion rate and the Successive - Approximation architecture for low power consumption, and consists of two identical stages that consist of sample/hold circuit, low power comparator, voltage reference circuit and MDAC of binary weighted capacitor array. Proposed A/D converter is designed using 0.25${\mu}{\textrm}{m}$ CMOS technology The SNR is 80㏈ at a sampling rate of 10MHz with 1.95MHz sine input signal. When an 8bit 10MS/s A/D converter is simulated, the Differential Nonlinearity / Integral Nonlinearity (DNL/ INL) error are $\pm$0.5 / $\pm$2 LSB, respectively. The power consumption is 13㎽ at 10MS/s.

  • PDF

POLARIZATION OBSERVATIONS OF BACKGROUND RADIO SOURCES SEEN THROUGH THE SUPERNOVA REMNANT S 147

  • Kim, Kwang-Tae
    • Journal of The Korean Astronomical Society
    • /
    • v.21 no.2
    • /
    • pp.133-153
    • /
    • 1988
  • Linear polarization has been measured for fifteen extragalactic radio sources in the field of supernova remnant S 147. These observations were made at 4885, 4835, 1665, 1515, 1465, and 1385 MHz using the Very Large Array, primarily to determine unambiguous Rotation Measures (RM) of the sources. This yields a total of 11 new RM sources. Comparisons of a sample of sources which are seen through S 147 were made with sources located farther away. The result tentatively indicates that the distribution of the rotation measure of the former population is broadened, with more than a 85% level of confidence. This constitutes evidence that there is a SNR contribution to rotation measure in sources seen through the SNR. Limits on this RM contribution are statistically at 30 < | RM | < 70 rad $m^{-2}$ with a 85% statistical level of confidence. These result imply the magnetic field in the rim of S 147 has strength 10 microguass if the electron density is $1\;cm^{-3}$.

  • PDF

Manufacturing of Micro Dotting Pin (DNA Chip 용 마이크로 핀에 관한 연구)

  • 신홍규;이영수;남권선;김병희
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
    • /
    • 2004.10a
    • /
    • pp.500-504
    • /
    • 2004
  • The bio-micro pin has been usually used for the biochemistry analysis. The manufacturing capability of the micro-pin and the their array with the effective and low-cost way is very important and it gives great economical benefits to developers. The micro-pin is composed of the sample channel for holding the liquid with the fixed volume, the flat tip which determines the printing quality and the pin head for preventing the rotation of the pin in the holder. In this study, we have manufactured newly designed micro-pins by the wire-EDM process with special jigs, and analyzed liquid holding and printing characteristics with respect to the variation of the shape and the tip size of the micro-pin.

  • PDF

Measurements of Local Coercivity Distribution in Ferromagnetic Films Using Magneto-Optical Microscope Magnetometer (MOMM)

  • Choe, Sug-Bong;Shin, Sung-Chul
    • Journal of Magnetics
    • /
    • v.5 no.3
    • /
    • pp.81-84
    • /
    • 2000
  • A magneto-optical microscope magnetometer (MOMM) has been developed to simultaneously measure 2-dimensional array hysteresis loops of each local area of $320\times320-nm^2$ spots on ferromagnetic films, in addition to grabbing time-resolved domain evolution patterns. Using the system, spatial distribution of local coercivity can be quantitatively generated and then, compared directly with domain patterns grabbed at precisely the same position of a sample. It is clearly demonstrated that local coercivity distribution governs domain reversal behavior via a thermally activated relaxation process.

  • PDF

Interlaminar Flux Density Distribution at Joints of Overlapping Stacked Electrical Steel and Amorphous Ribbons

  • Erdem, Sezer;Derebasi, Naim
    • Journal of Magnetics
    • /
    • v.15 no.4
    • /
    • pp.190-193
    • /
    • 2010
  • The design of joints in a transformer core significantly affects the transformer's efficiency. Air gaps cause variations in the flux distribution at the joints of the laminations, which depend on the geometry. Two similar samples consisting of electrical steel strips and amorphous ribbons were made. The spatial flux distributions were determined using an array of search coils for each sample. 2D models of these samples were created and examined by finite element analysis. The magnetic flux distribution for each lamination in the samples was computed. The results show that the flux density in amorphous ribbons above and below the air gap starts to approach saturation at lower flux density levels than for electrical steel. The flux density measured using the search coil under the air gap is increased in amorphous ribbons and decreased in the electrical steel with increasing frequency.