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Effect of the Oryungsan on the injured liver in CCl4-treated rats (오령산(五?散)이 CCl4 투여(投與)로 인한 흰쥐의 손상간(損傷肝)에 미치는 영향(影響))

  • Kown, Oh Sung;Choi, Hong Sik;Lee, Joon Hee;Kang, Yoon Ho
    • The Journal of Dong Guk Oriental Medicine
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    • v.5
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    • pp.131-147
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    • 1996
  • This study was investigated to define effect of pretreatment of Oryungsan on hepatotoxicity induced by $CCl_4$ in rat. The experimental anmals were divided into normal group, control group, sample group, and sample group were divided sample1, sample2, sample3. Control group were injected diluted carbon tetrachloride and olive oil, $1m{\ell}/kg$ to intraperitoneal after 8th day. Sample group were injected Oryungsan water extracts, $0.33m{\ell}/kg/day$ to intraperitoneal of sample group1, $0.66m{\ell}/kg$ day to sample group2, $1.32m{\ell}/kg/day$ to sample group 3 each other for 7day, and injected the dosage of $CCl_4$ was $1.0m{\ell}/kg$ diluted 1 : 1 with olive oil after 8th day. The following results were made by observation GOT, GPT, Albumin, Globulin, Bile acid, hepatic tissue. 1. The serum GOT and GPT level of sample group were decreased. Sample group 1 were decreased significantly. 2. The serum A/G ratio of sample group was increased as compared with normaI group. 3. The serum bile acid of sample group was decreased significantly. 4. The destruction of hepatic tissue were repaired as compared with control group. These results demonstrated that oryungsan can be attributed to recovery from hepatotoxicity.

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An Overview of Bootstrapping Method Applicable to Survey Researches in Rehabilitation Science

  • Choi, Bong-sam
    • Physical Therapy Korea
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    • v.23 no.2
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    • pp.93-99
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    • 2016
  • Background: Parametric statistical procedures are typically conducted under the condition in which a sample distribution is statistically identical with its population. In reality, investigators use inferential statistics to estimate parameters based on the sample drawn because population distributions are unknown. The uncertainty of limited data from the sample such as lack of sample size may be a challenge in most rehabilitation studies. Objects: The purpose of this study is to review the bootstrapping method to overcome shortcomings of limited sample size in rehabilitation studies. Methods: Articles were reviewed. Results: Bootstrapping method is a statistical procedure that permits the iterative re-sampling with replacement from a sample when the population distribution is unknown. This statistical procedure is to enhance the representativeness of the population being studied and to determine estimates of the parameters when sample size are too limited to generalize the study outcome to target population. The bootstrapping method would overcome limitations such as type II error resulting from small sample sizes. An application on a typical data of a study represented how to deal with challenges of estimating a parameter from small sample size and enhance the uncertainty with optimal confidence intervals and levels. Conclusion: Bootstrapping method may be an effective statistical procedure reducing the standard error of population parameters under the condition requiring both acceptable confidence intervals and confidence level (i.e., p=.05).

Effects of Yukgunja-Tang on Secretion of Gastric Juice and Movements of Isolated Stomach (육군자탕(六君子湯)이 위액(胃液) 분비(分泌) 및 적출(摘出) 위(胃) 운동(運動)에 미치는 영향(影響)에 관한 연구(硏究))

  • Chang, In-Kyu;Park, Sung-Il
    • Korean Journal of Pharmacognosy
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    • v.15 no.3
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    • pp.128-133
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    • 1984
  • The extracts of Yukgunja-tang which has been used in some of gastroin testinal disorders were examined for secretion of gastric juice and movement of isolated stomach of rabbit. Experiments were performed with the dried extract of Yukgunja-tang (sample I) and the dried extract compound made of each drug of Yukgunja-tang (sample II). The secretion of gastric juice at the doses of 25.0 and 50.0mg/kg p.o. of sample I showed the decreases of 34.3 and 43.3%, respectively, as compared with control group, whereas the secretion at a dose of 76.8g/kg of sample II showed 43.1%. In gastric acid secretion, sample I showed 50.0% decrease at a dose of 50.0mg/kg and sample II showed 46.2% decrease at a dose of 76.8mg/kg. In pepsin output sample I showed 17.8 and 23.4% decreases at a dose of 25.0 and 50.0mg/kg, respectively, whereas sample II showed 22.5% decrease at a dose of 76.8mg/kg. The isolated stomach of rabbit showed dose-responsive contraction by addition of sample I, however the contraction was not observed by sample II.

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Development of Multi Sample Array System Based on Pneumatic Valve (공압식 미세밸브를 이용한 다중유체 배열장치 개발)

  • Kim, Chul Min;Park, Seo Jung;Kim, Gyu Man
    • Journal of the Korean Society for Precision Engineering
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    • v.34 no.1
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    • pp.59-63
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    • 2017
  • We present a multi-sample array device based on a pneumatic system. Solenoid valves were used to control a micro valve in a pneumatic system. The use of a compressor together with a vacuum pump ensured that one outlet could supply both compression and vacuum pressure. The multi-sample array device was fabricated using conventional photolithography and PDMS casting. The device was composed of a multiplexer, sample array, and rinsing. The multiplexer could control four sample solutions injecting into the sample array chamber. Sample solution not arrayed was removed by DI-water from the rinsing inlet. To prevent trapping of microbubbles in the channel during injection of sample solution into the device, surfactant was added in PDMS solution to serve as a hydrophilic surface treatment. As a result, the device could be used as a sample array for 64 cases, using four samples and three columns of three chambers.

Development of Asbestos Quality Control Sample for Proficiency Analytical Testing 1 - Development of Manufacturing Apparatus and Sample Preparing Procedure for Asbestos Quality Control Sample - (석면분석 정도관리용 표준시료 개발연구 I - 석면분석 정도관리용 표준시료 제조장치 개발 및 시료제조 방법 확립 -)

  • Yi, Gwang Yong;Lee, Jong- Han;Jung, Sijeong;Park, Doo Yong
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.19 no.2
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    • pp.81-87
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    • 2009
  • Final purpose of this study was designed to develop the quality control(QC) sample for proficiency analytical testing of asbestos. This study consisted of two parts; first, development of manufacturing apparatus and sample preparing procedure for asbestos quality control(QC) sample: second, validation of the QC samples made by our developed method as asbestos proficiency analytical testing sample. The main results of the first part research are as followed We developed the apparatus for manufacturing the asbestos QC sample, consisted of filter hold, filter holder manifolder, vacuum system, and vacuum pump. The most proper filter of making the QC samples was a cellulose ester membrane filter with 25 mm diameter, pore size 0.8 um. And we presented the optimal procedure for preparing the asbestos QC sample by using the developed apparatus. We will verify the manufactured asbestos QC samples by this method, and present the validation results to confirm the reliability as a asbestos QC sample in next paper.

Variation in the Residual Stress of Hastelloy X Superalloy Fabricated by the Laser Powder Bed Fusion Process with Sample Thickness and Support Structure (레이저 분말 베드 용융법으로 제작된 Hastelloy X 적층 소재의 시편 두께 및 서포트 구조에 따른 잔류응력 변화)

  • Jang, J. E.;Park, S. H.;Kim, D. H.
    • Transactions of Materials Processing
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    • v.31 no.3
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    • pp.136-142
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    • 2022
  • The purpose of this study was to investigate the effects of sample thickness and support structure on the residual stress of Hastelloy X superalloy samples fabricated by laser powder bed fusion (LPBF), which is an additive manufacturing process. The residual stresses of LPBF samples with different thicknesses and support structures were measured using X-ray diffraction. The results revealed that as the thickness of sample increased from 2.5 mm to 20 mm, its tensile residual stress gradually decreased from 443.5 MPa to 182.2 MPa. Additionally, the residual stress in the bottom region of sample was higher than that in the top region, and the residual stress difference in the bottom and top regions became more pronounced as the sample thickness decreased. The residual stress of LPBF sample also varied depending on the structure of support. The residual stress of sample decreased with increasing contract area between the sample and the support, because the larger contract area led to smaller temperature gradient throughout the sample.

Sample size estimation using nomogram in dental research (치의학 연구에서 노모그램을 이용한 표본수 계산)

  • Kim, Ki-Yeol
    • The Journal of the Korean dental association
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    • v.54 no.8
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    • pp.630-638
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    • 2016
  • The appropriate sample size calculation in dental research is important to achieve the study purpose at the first step in study design. However, it cannot be easy to calculate sample size using standard formulas, because the several factors must be considered for calculation. This study introduced the graphic method for sample size calculation, which is called nomogram. The purpose of this study is to show the effectiveness of the nomogram using examples, expecting the researchers can easily use nomogram for sample size determination.

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$KMnO_4$를 이용한 TCE 제거 실험 연구(I): -Headspace sample과 liquid sample 분석과 비교-

  • 현승규;우남칠;최인혁;이기철
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2004.04a
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    • pp.370-375
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    • 2004
  • KMnO$_4$에 의한 TCE 용액의 분해에서 Headspace를 가진 반응 용기는 liquid sample을 headspce의 관측값으로 반응의 특성을 나타낼 수 없다. 이런 특성에 의해 in-situ KMnO$_4$ 이용은 TCE의 제거 효율에서 자연적인 휘발을 고려해야한다. 1:2.45 몰비에서 liquid sample의 결과 반감기는 약 80분이고 160분에 약 67%의 제거율을 보인다. 1:12.27 몰비의 경우 반감기는 10분이고 90분에 95%의 제거효율을 보인다.

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A Sample Design for Forestry Management Survey

  • Lee, Kay-O;Yoo, Jeongbin
    • Communications for Statistical Applications and Methods
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    • v.8 no.3
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    • pp.739-751
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    • 2001
  • In this paper, a sample design is studied for 2000 forestry management survey of five types forestry , tree felling, gathering of pine mushroom, growing of nut trees, growing of wild flowers, and lumbering industry. We introduce population stratification and a modified stratified cut-off sampling which deal with determination of sample size, sample allocation, and estimation of total and variance of estimator. Substitution of sample units and imputation of nonresponse units are discussed for reducing the nonsampling errors.

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Estimation of the Mean and Variance for Normal Distributions whose Both Sides are Truncated

  • Hong, Chong-Sun;Choi, Yun-Young
    • Communications for Statistical Applications and Methods
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    • v.9 no.1
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    • pp.249-259
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    • 2002
  • In order to estimate the mean and variance for a Normal distribution which is truncated at both right and left sides, maximum likelihood estimators based on the entire sample from the original distribution are compared with the sample mean and variance of the censored sample which is the data remaining after truncation using simulation. We found that, surprisingly, the mean squared error of the mean based on the censored data Is smaller than that of the full sample estimators.