• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2019.05a
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• pp.533-536
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• 2019

Recombinant baculoviruses are widely used to express heterologous genes in cultured insect cells. Recombinant baculoviruses can serve as gene-transfer vectors for expression of recombinant proteins in a wide range of mammalian cell types. Baculovirus system has significant benefits in view of safety, large-scale, and high level of gene expression. In this study, baculoviral vectors which were reconstructed from pOPINEneo-3C-GFP vector, were recombined with cytomegalovirus (CMV) promoter, green fluorescent protein (GFP), and p53 with NcoI and XhoI. These recombinant vectors were infected with various cells and cell lines. The baculovirus vector thus developed was analyzed by comparing the metastasis and expression of the recombinant genes with conventional vectors. These results suggest that the baculovirus vector has higher efficiency in metastasis and expression than the control vector. This work was supported by a grant from Mid-Career Researcher Program(NRF-2016R1A2B4016552) through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT & Future Planning(MSIP).

• Journal of the Korean Society for Environmental Technology
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• v.19 no.6
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• pp.576-585
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• 2018

Systematic management during the whole life cycle from construction to operation and maintenance is very important for the seven underground pipelines (waterworks, sewerage, electricity, telecommunications, gas, heating, oil including waterworks and sewerage). Especially, it is the construction process that affects the whole life cycle of underground buried pipeline. In order to construct a new city or to maintain different underground pipes, it is always necessary to dig the ground and carry out construction and related work. There is a possibility that secondary and tertiary breaks frequently occur in the pipeline construction process after the piping constructed first in this process. To solve this problem, a system is needed which can monitor damage in real time. However, the supply of electric power for continuous operation of the system is limited according to the environment of underground buried pipelines, so it is necessary to develop a stable electric power supply system using natural energy rather than existing electric power. In this study, we developed a system that can operate the pipeline monitoring system for long time (24 hours and 15 days) using natural energy using wind and solar light.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.3
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• pp.597-602
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• 2021

Even in the era of the 4th industrial revolution, the prevention of industrial accidents is still an important issue in industrial sites. In solving the problem of industrial safety, a product can be difficult to market if there is a lack of standard or method for a reliable performance evaluation. The purpose of this study was to develop and evaluate a test method for a wearable airbag product for protecting the body from falls that was newly developed to respond to fall accidents in industrial sites. As a research method, reliable evaluation standards were developed and applied through four stages of the evaluation and development process (Step 1: Product review, Step 2: Data research, Step 3: Expert meeting, Step 4: Drawing evaluation standard). In addition, the impact force was evaluated according to the developed evaluation standard. The fall impact force obtained through the evaluation showed a reduction effect of approximately 96% compared to the existing impact force. Therefore, the fall impact force was reduced significantly when the airbag was applied. This will enable new convergence products to be launched on the market and produce an environment where industrial workers can work safely.

• Journal of Korean Academy of Dental Administration
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• v.8 no.1
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• pp.15-23
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• 2020

The aim of this study is to identify future-oriented tasks for Korean dental hygienists based on a literature review. A literature search is performed using 14 keywords related to tasks carried out by dental hygienists, and included articles published from 2000 to 2019 in the databases KISS, RISS, DBpia, NDSL, Papersearch, Pubmed, and Google Scholar. Six reviewers assessed the titles and abstracts of articles, and an article was selected if the study was considered to cover future-oriented tasks for Korean dental hygienists. Based on the results six local studies and two foreign studies were used for literature review and data extraction. In total, 38 tasks were classified as future-oriented tasks of dental hygienists according to the following criteria: 1) tasks that were specifically referred to as future-oriented tasks, and 2) tasks that could be classified as future-oriented tasks although no specific reference was made. Of these, the most frequently mentioned tasks were measuring periodontal pocket depth, dental hygiene assessment, providing dietary advice, infiltration anesthesia, and root planing. These were extracted from five of the eight studies, including both local and foreign studies. Dental hygiene planning, emergency, emergency management, and smoking cessation were the next most common tasks based on four studies. Even though some of these future-oriented tasks for Korean dental hygienists are included in the dentistry curriculum, and are currently performed as clinical practice for dental hygienists. Nonetheless, the reference to the legal scope is unclear. It is necessary to reconsider the scope of tasks of dental hygienists to reflect changes in domestic and foreign dental care delivery, thereby contributing to the oral health promotion of the public, where safety is guaranteed under legal protection.

• Journal of Korea Water Resources Association
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• v.55 no.1
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• pp.43-57
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• 2022

Advances in measurement techniques have reduced measurement costs and enhanced safety resulting in less uncertainty. For example, an acoustic doppler current profiler (ADCP) based suspended sediment concentration (SSC) measurement technique is being accepted as an alternative to the conventional data collection method. In Korean rivers, horizontal ADCPs (H-ADCPs) are mounted on the automatic discharge monitoring stations, where SSC can be measured using the backscatter of ADCPs. However, automatic discharge monitoring stations and sediment monitoring stations do not always coincide which hinders the application of the new techniques that are not feasible to some stations. This work presents and analyzes H-ADCP-SSC models for 9 discharge monitoring stations in Korean rivers. In application of the Gaussian mixture model (GMM) to sediment-related variables (catchment area, particle size distributions of suspended sediment and bed material, water discharge-sediment discharge curves) from 44 sediment monitoring stations, it is revealed that those characteristics can distinguish sediment monitoring stations regionally. Linking the two results, we propose a protocol determining the H-ADCP-SSC model where no H-ADCP-SSC model is available.

• Korean Journal of Construction Engineering and Management
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• v.23 no.1
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• pp.64-72
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• 2022

The retaining wall structure is essential for construction work that performs underground excavation. Displacement management of the retaining wall structure is important regardless of the size of the construction. However, in the case of small-scale construction sites with an excavation depth of less than 10m, displacement management of retaining wall structure not properly performed due to problems such as 1) companies' smallness, 2) lack of capacity of construction managers, 3) complexity of installation, dismantling and displacement of measuring instruments. As a result of analyzing previous research, it was analyzed that it is difficult to apply this to a small - scale construction site because most of the previous research has problems in using an expensive 3D scanner or installing many measuring instruments. This study aims to propose a conceptual design of a displacement measurement system for retaining wall structure based on laser sensor and to verify the displacement recognition performance of core technology applied to the conceptual design. A conceptual design was proposed using a 2D laser scanner. As a result of verifying the displacement recognition of the 2D laser scanner, a displacement of 15mm was analyzed to be sufficiently understandable. In the future, if the proposed conceptual design is developed and applied to the small-scale construction site, it is thought that it will contribute to the reduction of safety accidents at small-scale construction sites.

• Journal of the Korea Convergence Society
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• v.13 no.3
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• pp.125-131
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• 2022

Recently, the prevalence of remotely managed patient care systems in medical institutions is increasing due to COVID-19. In particular, in the case of fluid monitoring, hospitals are considering introducing it as a system that can reduce patient safety and nurses' work. There are two products under development: a load cell method that measures weight and a method that detects drops of sap by infrared sensing. Although each product has differences in operation principle, sensor type, size, usage, and price, medical institutions are highly interested in the accuracy of the data obtained.In this study, two prototypes with different sensor methods were manufactured and the total amount of infusion per hour was measured to test the accuracy, which is the core of the infusion monitoring device. In addition, when there was an external movement, the change in the measured value of the sap was tested to evaluate the accuracy according to the measurement method. As a result of the experiment, there was a difference of less than 5% in the measurement value error of the two devices, and the load cell method showed a difference in the low-capacity measurement value and the infrared method in the high-capacity measurement value. As a result of this experiment, there was little difference in accuracy according to the sensor method of the infusion monitoring device, and it is considered that there is no problem in accuracy when used in a medical institution.

• Korean Journal of Clinical Pharmacy
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• v.31 no.4
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• pp.257-267
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• 2021

Background: The need for regulatory science development to evaluate advanced regulatory products is gradually increasing without hindering the technological development. Creating a research environment and fostering experts through the establishment of regulatory agency-led policies are essential for the development of regulatory science. Method: This is a comparative study of the United States, Japan, Singapore, and Korea. The literature and websites of each regulatory agency were reviewed, and the focus was on advantages and comparing advantages based on definition, development trends, and expert training projects. Results: The United States is striving to develop regulatory science in response to changes in the new pharmaceutical industry through the regulatory science report, and to foster expert both inside and outside the Food and Drug Administration (FDA). Japan is promoting regulatory science centered on regulatory science centers, and is focusing on researching work-related regulatory science within the Pharmaceuticals and Medical Devices Agency (PMDA) and improving employees' ability to make regulatory decisions. Singapore was aiming to improve Southeast Asia's regulatory capabilities under the leadership of Centre of Regulatory Excellence (CoRE) within Duke-NUS University. In 2021, Korea is in its early stages, starting to run a university's degree program related to regulatory science this year. Conclusion: Regulatory science should be developed with the aim of improving the regulatory ability of the Ministry of Food and Drug Safety with Korea's independent concept of regulatory science.

• Journal of Internet of Things and Convergence
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• v.8 no.2
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• pp.35-40
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• 2022

In the agricultural environment, pesticide control requires a high risk of work and a high labor force for farmers. The effectiveness of pesticide control using unmanned aerial vehicles varies according to climate, land type, and characteristics of unmanned aerial vehicles. Therefore, an effective method for pesticide control by unmanned aerial vehicles considering the spraying conditions and environmental conditions is required. In this paper, we propose an efficient pesticide control system based on agricultural unmanned aerial vehicles considering the application conditions and environmental information for each crop. The effectiveness of the proposed model was demonstrated by measuring the drop uniformity of pesticides according to the change in altitude and speed after attaching the sensory paper and measuring the penetration rate of the drug inside the canopy according to the change in crop growth conditions. Experiment result, the closer the height of the UAV is to the ground, the more evenly the crops are sprayed, but for safety reasons, 2m more is suitable, and on average a speed of 2m/s is most suitable for control. The proposed control system is expected to help develop intelligent services based on the use of various unmanned aerial vehicles in agricultural environments.

• Applied Chemistry for Engineering
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• v.33 no.1
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• pp.90-95
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• 2022

In the present work, biochar was prepared using Achyanthes japonica stem as a by-product of herbal medicine. In order to apply the prepared biochar to water treatment process, the adsorption characteristics of zinc and iron ions dissolved in water were investigated. When the experiments were performed for 2 h to remove 70 and 100 mg/L of zinc ions, the adsorption amounts of 32.3 and 31.0 mg/g were obtained, respectively. It was also found that the adsorption amount of Achyanthes japonica stem biochar for the removal process of zinc ion was three times higher than that of the activated carbon. In addition, when the experiments were performed for 2 h to treat 70 and 100 mg/L of iron ions, high adsorption amounts of 50.1 and 54.3 mg/g were achieved, respectively. In order to further enhance the removal efficiency of zinc and iron ions, a steam activation process was performed on the biochar of Achyanthes japonica stem. As a result, the removal efficiencies of 70 and 100 mg/L of zinc ions increased to 80 and 60%, respectively. Also, the removal efficiencies of 70 and 100 mg/L of iron ions were improved to 100 and 82%, respectively. In addition, when the biochar of Achyanthes japonica stem with a steam activation was compared with the untreated biochar of Achyanthes japonica stem, the specific surface area increased 37.3 times, and the total and macroporpous pore volumes were improved by 28.4 and 136 times, respectively. Therefore, the results can be used for economically and practically adsorbing zinc and iron ions contained in water.