• Title/Summary/Keyword: Safety test

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Status of Fusarium Wilt Incidence on Summer Radish and Etiological Characteristics of the Causal Fungus in Korea (고랭지 여름 무에서 시들음병 발생 현황과 병원균의 병원학적 특성 연구)

  • Hong, Sung Kee;Ko, Hyoungrai;Choi, Hyo-Won;Lee, Youngkee;Kim, Jeomsoon
    • Research in Plant Disease
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    • v.26 no.4
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    • pp.256-263
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    • 2020
  • Incidence of Fusarium wilt was surveyed in fields of summer radish in Gangwon province in Korea in 2018 and 2019. The disease started in early July and spread rapidly in hot summer of late July and August and in severe case, reached up to 80% in a field in Gangneung area. Symptoms in the seedling stage include poor growth and browning of internal tissue of root. During mid-growth, the leaves of diseased plant turned yellow over time, the surface of the roots changed from white to blackish, and the vascular tissues turned brown. A total of 23 isolates was obtained from the diseased plants and identified as Fusarium oxysporum f. sp. raphani by elongation factor-1α and intergenic spacer sequence analysis. Pathogenicity of the isolates was tested by artificial inoculation to the radish and other plants. All the isolates tested were pathogenic to radish plant, although there were differences in virulence on radish 11 cultivars. However, the isolates were not virulent to other plants except some cruciferous vegetables including Brussels sprouts, rocket, stock, and turnip. The results of pathogenicity test showed that it is necessary to rotate with crops other than cruciferous vegetables in order to prevent Fusarium wilt from radish fields.

Method for evaluating the safety performance and protection ability of the mobile steel protective wall during the high-explosive ammunition test (고폭탄 탄약시험 간 이동형 강재 방호벽의 안전성능 판단 및 유효 방호력 평가 방법)

  • Jeon, In-Beom
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.6
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    • pp.573-582
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    • 2021
  • In this study, a series of processes for evaluating the effective protection against barriers that should be equipped in institutions that perform reliability tests on high-risk ammunition, such as high-explosive ammunition, were introduced. The impact that high-explosive bombs can have on personnel includes damage to the eardrum and lungs caused by explosion overpressure and penetrating wounds that can be received by fragments generated simultaneously with the explosion. Therefore, a high-explosive with COMP B explosives as its contents were set up, and an explosion protection theory investigation to calculate the degree of damage, numerical calculations and simulations were performed to verify the protection power. A numerical calculation revealed the maximum explosion overpressure on the protective wall when the high-explosive exploded and the penetration force of the fragment against a 50 mm-thick protective wall to be 77.74 kPa and 41.34 mm, respectively. In the simulation verification using AUTODYN, the maximum explosion overpressures affecting the firewall and personnel were 56.68 kPa and 18.175 kPa, respectively, and the penetration of fragments was 35.56 mm. This figure is lower than the human damage limit, and it was judged that the protective power of the barrier would be effective.

Structural Characteristics Analysis of Steel Box Girder Bridge being stressed the PS Steel Wires at the Upper Slab of the Intermediate Support (지점부 상부슬래브에 PS강선 긴장된 강 박스거더교의 구조적 특성 분석)

  • Cha, Tae-Gweon;Jang, Il-Young
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.25 no.2
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    • pp.1-7
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    • 2021
  • The concrete deck slab at the continuous span support of the steel box girder bridge is a structure that is combined with the upper flange. It is a structure that can cause tension cracks in the deck slab at the support causing problems such as durability degradation in long span bridges. This is because the tensile stress in the longitudinal direction of the slab exceeds the design tensile strength due to the effects of dead load and live load when applying a long span. Accordingly, it is necessary to control tensile cracking by adding a reinforcing bar in the axial direction to the slab at the support and to introduce additional compressive stress. To solve this problem, a structural system of a steel box girder bridge was proposed that introduces compressive stress as PS steel wire tension in the tensile stress section of the upper slab in the continuous support. The resulting structural performance was compared and verified through the finite element analysis and the steel wire tension test of the actual specimen. By introducing compressive stress that can control the tensile stress and cracking of the slab generated in the negative moment through the tension of the PS steel wire, it is possible to improve structural safety and strengthen durability compared to the existing steel box girder bridge.

A Study on Optical Design Factors by Artificial Recharge Performance (인공함양 주입성능평가에 의한 설계요소 산정 연구)

  • Won, Kyoung-Sik;Lee, Yeoung-Dong;Shin, Dong-Min;Kim, Byeong-Jun;Kim, Gyoo-Bum
    • The Journal of Engineering Geology
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    • v.30 no.4
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    • pp.603-615
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    • 2020
  • The design factors of artificial recharge are determined by considering the hydrogeological characteristics of the aquifer. The optimal design factors for artificial recharge were derived after performing the injection tests step by step for each injection type (vertical well, ditch and mixed type), which were built in the test site of the study area. It was analyzed that the difference in the injection effect according to the diameter of the injection well was not large, and the 100 mm well was evaluated as appropriate in consideration of the availability and economy of land use. Since the injection effect was well maintained even in the upper rock, the depth of the injection well was proposed for the alluvial layer and the upper rock layer. On the other hand, in four cases of filter media in the ditch, it was analyzed that the penetration efficiency and the hydraulic interference effect indicated excellent injection performance when a filter medium of 10 to 30 mm diameter was filled in the ditch. In addition, the proper spacing of the injection wells was analyzed as 9~12 m considering the interference efficiency. The interference efficiency attenuation coefficient per 1 m of hole spacing was calculated to be 1.75% in this area. In the future study, the artificial recharge design factors obtained in this stage are applied and verified on site construction and operation. Also it is expected to contribute to securing water in areas where there is always a lack of water.

Modeling and Simulation for Analyzing Efficient Operations on Public Bike System: A Case Study of Sejong City (공공 자전거 시스템의 효율적 운용을 위한 모델링 및 시뮬레이션: 세종시 사례 중심)

  • Bae, Jang Won;Choi, Seon Han;Lee, Chun-Hee;Paik, Euihyun
    • Journal of the Korea Society for Simulation
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    • v.30 no.1
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    • pp.103-112
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    • 2021
  • In recent years, public bicycle systems are widely spread over the world according to the development of ICT technology. Since the public bicycle systems in large cities need to secure both publicity and convenience for citizens, analysis of various their issues from introduction to operation is required. In addition, it is also necessary to prepare for various scenarios for coexistence with the PM business, which is recently in the spotlight as a last mile means and normally managed privately. This paper introduces modeling and simulation for efficient operations of public bicycle systems. In particular, the proposed method was developed in a form that can be easily used in other cities by modeling the general structure and behavior of the public bicycle system, and it was developed to facilitate modification and expansion of the future model with a component-based model configuration. This paper provides a case study of the propose method, which is the public bicycle simulation in Sejong City. The simulation results were derived by applying the data from the public bicycle system of Sejong City, and they were verified with the associated real data of Sejong City. Using the verified model, it is expected that it can be used as a tool to design and analyze various services on the public bicycle systems, which were especially suitable for Sejong City.

Quality Control Tests and Acceptance Criteria of Diagnostic Radiopharmaceuticals (진단용 방사성의약품의 품질관리시험 및 기준)

  • Park, Jun Young
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.1
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    • pp.1-10
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    • 2021
  • Radiopharmaceuticals are drugs that contain radioisotopes and are used in the diagnosis, treatment, or investigation of diseases. Radiopharmaceuticals must be manufactured in compliance with good manufacturing practice regulations and subjected to quality control before they are administered to patients to ensure the safety of the drug. Radiopharmaceuticals for administration to humans need to be sterile and pyrogen-free. Hence, sterility tests and membrane filter integrity tests are carried out to confirm the asepticity of the finished drug product, and a bacterial endotoxin test conducted to assess contamination, if any, by pyrogens. The physical appearance and the absence of foreign insoluble substances should be confirmed by a visual inspection. The chemical purity, residual solvents, and pH should be evaluated because residual by-products and impurities in the finished product can be harmful to patients. The half-life, radiochemical purity, radionuclidic purity, and strength need to be assessed by analyzing the radiation emitted from radiopharmaceuticals to verify that the radioisotope contents are properly labeled on pharmaceuticals. Radiopharmaceuticals always carry the risk of radiation exposure. Therefore, the time taken for quality control tests should be minimized and care should be taken to prevent radiation exposure during handling. This review discusses the quality control procedures and acceptance criteria for a diagnostic radiopharmaceutical.

Comparative analysis of fusion factors affecting the accuracy of injection amount of remote fluid monitoring system (원격 수액모니터링 시스템의 주입량의 정확도에 영향을 주는 융합인자의 비교 분석)

  • Kim, Seon-Chil
    • Journal of the Korea Convergence Society
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    • v.13 no.3
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    • pp.125-131
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    • 2022
  • Recently, the prevalence of remotely managed patient care systems in medical institutions is increasing due to COVID-19. In particular, in the case of fluid monitoring, hospitals are considering introducing it as a system that can reduce patient safety and nurses' work. There are two products under development: a load cell method that measures weight and a method that detects drops of sap by infrared sensing. Although each product has differences in operation principle, sensor type, size, usage, and price, medical institutions are highly interested in the accuracy of the data obtained.In this study, two prototypes with different sensor methods were manufactured and the total amount of infusion per hour was measured to test the accuracy, which is the core of the infusion monitoring device. In addition, when there was an external movement, the change in the measured value of the sap was tested to evaluate the accuracy according to the measurement method. As a result of the experiment, there was a difference of less than 5% in the measurement value error of the two devices, and the load cell method showed a difference in the low-capacity measurement value and the infrared method in the high-capacity measurement value. As a result of this experiment, there was little difference in accuracy according to the sensor method of the infusion monitoring device, and it is considered that there is no problem in accuracy when used in a medical institution.

Does Vitex Agnus-Castus L. Have Deleterious Effect on Fertility and Pregnancy Outcome? An Experimental Study on Rats for Prediction of Its Safety

  • Najib, Fateme Sadat;Poordast, Tahereh;Mahmudi, Monireh Sufi;Shiravani, Zahra;Namazi, Niloofar;Omrani, Gholamhossein Ranjbar
    • Journal of Pharmacopuncture
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    • v.25 no.2
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    • pp.106-113
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    • 2022
  • Objectives: Herbal medicine is a worldwide health topic. Vitex agnus-castus L. (VAC) is a popular plant used for gynecologic problems due to its hormonal effects. The aim of this study is to reveal VAC extract effect on fetus when this herb is used started from antenatal period or during pregnancy. Methods: Performed from starting day of January 2019 till February 2019, 48 rats were assigned in randomly divided eight-member six groups: control (C1), treated group with 365 mg/kg VAC from initiation of insemination (T1) and 30 days prior to pregnancy (T2), control that underwent caesarean section on 15th day of gestational age (C2) and treated group with 365 mg/kg VAC from initiation of insemination (T3) and 30 days prior to pregnancy (T4) that underwent caesarean section. Weight, sex and number of fetuses, abortion and still birth rate and estradiol level were evaluated using t-test by SPSS software. Results: We showed increased weight among T1 group considering totally and sex-dependent which is significant (all p-value < 0.05). We also detected significantly decreased weight in T2 in total (p-value < 0.0001) and when considering female fetuses (0.043) but not males (0.17). Although the results showed slightly non-significant increased weight among fetuses of T3 (totally or based on the fetus sex) compared to the control group (C2), T4 group had statistically decreased weight compared to control group. Pregnancy rate and pregnancy outcome were affected by VAC usage. The time of VAC initiation also affected live birth and abortion rates. Conclusion: VAC extract may affect pregnancy rate, live birth rate, abortion and stillbirth rates. Its effect on the weight and the sex showed dual pattern depends on the time of initiation and pregnancy trimester of evaluation. Prescribing this medicinal plant for patients being prone to pregnancy should be with caution. Further study is recommended.

Predictive Analysis of Fire Risk Factors in Gyeonggi-do Using Machine Learning (머신러닝을 이용한 경기도 화재위험요인 예측분석)

  • Seo, Min Song;Castillo Osorio, Ever Enrique;Yoo, Hwan Hee
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.39 no.6
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    • pp.351-361
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    • 2021
  • The seriousness of fire is rising because fire causes enormous damage to property and human life. Therefore, this study aims to predict various risk factors affecting fire by fire type. The predictive analysis of fire factors was carried out targeting Gyeonggi-do, which has the highest number of fires in the country. For the analysis, using machine learning methods SVM (Support Vector Machine), RF (Random Forest), GBRT (Gradient Boosted Regression Tree) the accuracy of each model was presented with a high fit model through MAE (Mean Absolute Error) and RMSE (Root Mean Squared Error), and based on this, predictive analysis of fire factors in Gyeonggi-do was conducted. In addition, using machine learning methods such as SVM (Support Vector Machine), RF (Random Forest), and GBRT (Gradient Boosted Regression Tree), the accuracy of each model was presented with a high-fit model through MAE and RMSE. Predictive analysis of occurrence factors was achieved. Based on this, as a result of comparative analysis of three machine learning methods, the RF method showed a MAE = 1.765 and RMSE = 1.876, as well as the MAE and RMSE verification and test data were very similar with a difference between MAE = 0.046 and RMSE = 0.04 showing the best predictive results. The results of this study are expected to be used as useful data for fire safety management allowing decision makers to identify the sequence of dangers related to the factors affecting the occurrence of fire.

Suggestion of Korea's Deep Space Exploration Roadmap through Participation to the Artemis International Manned Lunar Exploration Program (한국의 Artemis 국제공동 유인달탐사 참여를 중심으로 우리나라 심우주탐사 로드맵 제안)

  • Choi, Gi-Hyuk;Kim, Dae-Yeong
    • Journal of Space Technology and Applications
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    • v.2 no.1
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    • pp.52-65
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    • 2022
  • Korea is near close the success on the indigenous launch vehicle KSLV-2 after the second test launch during the second half of 2022, and the satellite development has been already in the level of advanced country. After the such mature of satellite and launch vehicle technologies, Korea's space development main theme should be 'Space Exploration and Space Application', and paradigm should be changed from 'Hardware' to 'Scientific/Technological Mission', from 'Unmanned' to 'Manned'. Korea's prime space strategy should be the direction of expansion of space industry, creation of employment and secure the key technologies, improvement of convenience and safety of people. For the purpose it is necessary to start 'Manned Space Development' such that participation to 'Artemis and Gateway Program' in 20s' and manned Mars exploration in 30s' which would be carried out by means of global international cooperation, and which could be a good opportunity to explore the new area of space development and upgrade national technology capability. Taking advantage of this opportunity, it is required for Korea to join the international programs through developing indigenous challenging, sustainable Korean mission and hardware. Also selection of the 2nd Korean Astronaut could draw national attention, especially could give dreams to young generation. Participation to the Artemis program could be the opportunity of entering the major space fairing nation and boosting up national pride. In this study we survey and analyze the Artemis Program in detail, and in conclusion we suggest the strategy of Korea's participation to the Artemis Program.