• Title/Summary/Keyword: Safety test

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Analysis of Telephone Follow-up Data of Out-patient Anesthesia for Dental Treatment of Disability Patients (치과장애인 환자의 외래마취 하 치과치료 귀가 후 전화추후 관리 분석)

  • Kim, Mi-Seon;Seo, Kwang-Suk;Lee, Jung-Man;Kim, Hye-Jung;Han, Jin-Hee;Han, Hee-Jeong;Lee, Eun-Hee;Shin, Soonyoung;Shin, Teo-Jeon;Kim, Hyun-Jeong;Chang, Juhea
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.12 no.2
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    • pp.93-97
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    • 2012
  • Background: Some disabled patients show insufficient cooperation during dental treatment, and general anesthesia in an outpatient setting can be successfully administered. To minimize post-anesthetic complications is an essential issue, and strict discharge protocols are required for the safety of the patients. Post-anesthetic follow-ups using telephone calls can be applied to improve the quality of the outpatient care system. The authors evaluated the post-operative condition of patients after dental treatment under general anesthesia. Methods: Total 143 patients and their caregivers included in this study. The patients received general anesthesia for dental treatment in Seoul National University Dental Hospital, Clinic for Persons with Disabilities from July, 2011 to April, 2012. Telephone calls were given to the patients or their caregivers to collect information about the patients' systemic condition and anesthesia-related complications. Results: Among 131 patients with responses of telephone calls, 87 patients (66.4%) reported no discomfort, while 44 patients (33.6%) presented post-anesthetic complications. A total of 20 patients reported mild fever, 10 patients had vomiting, and 7 patients had sore throat. Other complications included nausea, fatigue, nasal bleeding, skin sore, and body rash. Among the patients with the history of epilepsy, 63.6% showed post-anesthetic discomfort or complication (P = 0.027, ${\chi}^2$ test). Conclusions: One third of dental patients who received general anesthesia due to insufficientcooperation complained discomfort after discharged from outpatient anesthetic care.

Influence of Carbonation on the Chloride Diffusion in Concrete (탄산화 현상이 콘크리트 중의 염소이온 확산에 미치는 영향 연구)

  • Oh, Byung-Hwan;Lee, Sung-Kyu;Lee, Myung-Kue;Jung, Sang-Hwa
    • Journal of the Korea Concrete Institute
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    • v.15 no.6
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    • pp.829-839
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    • 2003
  • Recently, the corrosion of reinforced concrete structures has received great attention related with the deterioration of sea-side structures, such as new airport, bridges, and nuclear power plants. In this regards, many studies have been done on the chloride attack in concrete structures. However, those studies were confined mostly to the single deterioration due to chloride only, although actual environment is rather of combined type. The purpose of the present study is, therefore, to explore the influences of carbonation to chloride attack in concrete structures. The test results indicate that the chloride penetration is more pronounced than the case of single chloride attack when the carbonation process is combined with the chloride attack. It is supposed that the chloride ion concentration of carbonation region is higher than the sound region because of the separation of fixed salts. Though the use of fly ash pronounces the chloride ion concentration in surface, amounts of chloride ion penetration into deep region decreases with the use of fly ash. The present study allows more realistic assessment of durability for such concrete structures which are subjected to combined attacks of both chlorides and carbonation but the future studies for combined environment will assure the precise assessment.

Flexural Strength of PHC Pile Reinforced with Infilled Concrete, Transverse and Longitudinal Reinforcements (내부충전 콘크리트와 횡보강 및 축방향 철근으로 보강된 PHC 말뚝의 휨강도)

  • Bang, Jin-Wook;Hyun, Jung-Hwan;Lee, Bang-Yeon;Lee, Seung-Soo;Kim, Yun-Yong
    • Journal of the Korea Concrete Institute
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    • v.25 no.1
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    • pp.91-98
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    • 2013
  • The pre-tensioned spun high strength concrete (PHC) pile has poor load carrying capacity in shear and flexure, while showing excellent axial load bearing capacity. The purpose of this study is to evaluate the flexural performance of the concrete-infilled composite PHC (ICP) pile which is the PHC pile reinforced with infilled concrete, transverse and longitudinal reinforcement for the improvement of shear and flexural load carrying capacity. The ICP pile specimen was designed to make allowable axial compression and bending moment higher load bearing capacity than those determined through the investigation of abutment design cases. The allowable axial compression and bending moment of the ICP pile was obtained using the program developed for calculating the axial compression - bending moment interaction. Then, ICP pile specimens were manufactured and flexural tests were performed. From the test results, it was found that the maximum bending moment of the ICP pile was approximately 45% higher than that of the PHC pile and the safety factor of ICP pile design was about 4.5 when the allowable bending moment was determined to be 25% of the flexural strength.

A Model Test of IE and IR Method to Detect the Cavity Underneath the Concrete Structure (콘크리트 구조물 하부의 공동 탐지를 위한 충격반향(IE) 및 충격응답(IR) 기법의 모형 실험)

  • Noh, Myung-Gun;Oh, Seok-Hoon
    • Journal of the Korean earth science society
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    • v.32 no.1
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    • pp.1-11
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    • 2011
  • The impact echo and impulse response methods were applied to the safety inspection of concrete structure, which has the rear cavity. The concrete structure model used in this study was divided into four sections, pure concrete, concrete+cavity, reinforced concrete with iron bar, and reinforced concrete+cavity, respectively. Previous study performed by authors have showed a possibility of success to use these method for detection of the rear cavity of concrete structure. Therefore, we tried to get more enhanced result with IE and IR methods through this study. Especially, IE and IR methods are relatively accurate to map the point of measurement, which makes it possible to interpret the depth of the concrete bed and effect by rear cavity with confidence. Followings were revealed from the results; the IE method shows some small peak zones probably indicating the rear cavity in the frequency lower than the resonance frequency and the changes of mobility and dynamic stiffness in the IR method indicate the weak zones. The proposed methods can be used to delineate the weak zones of the concrete structure.

COMPARISON OF TRAMADOL/ACETAMINOPHEN AND CODEINE/ACETAMINOPHEN/IBUPROFEN IN ONSET OF ANALGESIA AND ANALGESIC EFFICACY FOR POSTOPERATIVE ACUTE PAIN (수술후 급성 동통에 대한 Tramadol/Acetaminophen과 Codeine/Acetaminophen/Ibuprofen의 효과 발현시점과 진통효과의 비교)

  • Jung, Young-Soo;Kim, Dong-Kee;Kim, Moon-Key;Kim, Hyung-Jun;Cha, In-Ho;Han, Moo-Young;Lee, Eui-Wung
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.2
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    • pp.143-149
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    • 2004
  • Background: Some clinical trials have reported that a new analgesic combination of tramadol and acetaminophen provides good efficacy in various pain models. For the more clinical uses of this agent, comparisons about the onset of analgesia and analgesic efficacy in the acute state of pain with the other drugs known as strong analgesics were needed. Purpose: The goal of this study was to compare the times to onset of analgesia and the other analgesic efficacy of 75 mg tramadol/650 mg acetaminophen and 20 mg codeine/500 mg acetaminophen/400 mg ibuprofen in the treatment of acute pain after oral surgery. Patients and Methods: Using a randomized, single-dose, parallel-group, single-center, and active-controlled test design, this clinical study compared the times to onset of analgesia using a two-stopwatch technique and the other analgesic efficacy of the single-dose tramadol/acetaminophen and codeine/acetaminophen/ibuprofen. These were assessed in 128 healthy subjects with pain from oral surgical procedures involving extraction of one or more impacted third molars requiring bone removal. From the time of pain development, the times to onset of perceptible and meaningful pain relief, pain intensity, pain relief, an overall assessment, and adverse events of the study medications were recorded for 6 hours. Results: The demographic distribution and baseline pain data in the two groups were statistically similar. The median times to onset of perceptible pain relief were 21.0 and 24.4 minutes in the tramadol/acetaminophen and codeine/acetaminophen/ibuprofen groups respectively and those to onset of meaningful pain relief were 56.4 and 57.3 minutes, which were statistically similar. The other efficacy variables such as mean total pain relief (TOTPAR) and the sum of pain intensity differences (SPID) were also similar in the early period after pain development and drug dosing. The safety of tramadol/acetaminophen was well tolerated and very comparable to that of codeine/acetaminophen/ibuprofen. Conclusions: In this acute dental pain model, the onset of analgesia and analgesic efficacy of tramadol/acetaminophen was comparable to that of codeine/acetaminophen/ibuprofen. These results showed that tramadol/acetaminophen was recommendable for fast and effective treatment in the management of postoperative acute pain.

Bioactive characteristics of an implant surface coated with a pH buffering agent: an in vitro study

  • Pae, Hyung-Chul;Kim, Su-Kyoung;Park, Jin-Young;Song, Young Woo;Cha, Jae-Kook;Paik, Jeong-Won;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • v.49 no.6
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    • pp.366-381
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    • 2019
  • Purpose: The purpose of this study was to evaluate the effectiveness of conventional sandblasted, large-grit, acid-etched (SLA) surface coated with a pH buffering solution based on surface wettability, blood protein adhesion, osteoblast affinity, and platelet adhesion and activation. Methods: Titanium discs and implants with conventional SLA surface (SA), SLA surface in an aqueous calcium chloride solution (CA), and SLA surface with a pH buffering agent (SOI) were prepared. The wetting velocity was measured by the number of threads wetted by blood over an interval of time. Serum albumin adsorption was tested using the bicinchoninic acid assay and by measuring fluorescence intensity. Osteoblast activity assays (osteoblast adhesion, proliferation, differentiation, mineralization, and migration) were also performed, and platelet adhesion and activation assays were conducted. Results: In both the wetting velocity test and the serum albumin adsorption assay, the SOI surface displayed a significantly higher wetting velocity than the SA surface (P=0.000 and P=0.000, respectively). In the osteoblast adhesion, proliferation, differentiation, and mineralization tests, the mean values for SOI were all higher than those for SA and CA. On the osteoblast migration, platelet adhesion, and activation tests, SOI also showed significantly higher values than SA (P=0.040, P=0.000, and P=0.000, respectively). Conclusions: SOI exhibited higher hydrophilicity and affinity for proteins, cells, and platelets than SA. Within the limits of this study, it may be concluded that coating an implant with a pH buffering agent can induce the attachment of platelets, proteins, and cells to the implant surface. Further studies should be conducted to directly compare SOI with other conventional surfaces with regard to its safety and effectiveness in clinical settings.

PASEM을 이용한 KSR-III Nose Fairing 분리운동 예측

  • Ok, Ho-Nam;Kim, In-Sun;Ra, Sung-Ho;Kim, Seong-Lyong;Oh, Beom-Suk
    • Aerospace Engineering and Technology
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    • v.2 no.1
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    • pp.171-181
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    • 2003
  • The nose fairings of KSR-III are designed to be separated from the rocket by explosive force at the mission altitude to expose the payload. Adequate amount of separation force should be imposed to allow safe separation without collision between the fairings and the rocket, and the separation device was designed for the separation at very high altitude where almost no air load was expected. As the development of KSR-III goes on, several design changes have made and lower separation altitude of 45km is expected as a result. Under these circumstances, it is required to determine if the nose fairings can be separated without collision with much severer air load than for the design condition. In this study, the 6-DOF motion analysis program, PASEM, which was developed to predict the strap-on booster separation, is modified to simulate the pivotal motion of the fairings at early stages of separation. The accuracy of pivot motion simulation is validated by comparison with the results of ground test and the accurate separation conditions are deduced from it. Trajectory simulations are performed to see if separation without collision is possible with varying angle of attack, direction of gravity, and the effect of gust. It is also found that reducing the separation angle of the clamshell hinge from 60 degrees to 40 degrees can enhance separation safety and separation at lower altitude of 40km can be done without collision.

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A Study on the Relationship of Job Satisfaction and Social Support of Dental Technicians (치과기공사의 직무만족도와 사회적 지원에 관한 조사)

  • Kwon, Eun-Ja;Han, Min-Soo;Choi, Esther
    • Journal of Technologic Dentistry
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    • v.36 no.2
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    • pp.99-110
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    • 2014
  • Purpose: This study was carried out in order to examine the relationship of job satisfaction and social support on the dental technicians and to analyze its influence. Methods: A self-reported questionnaire survey was carried out by having convenience sampling as 220 dental technicians who work in Seoul Metropolis, Gyeonggi-do Province, Daejeon and Chungnam Province. A research tool was used questionnaire that was proved reliability and validity. It was prepared with totally 37 questions such as 12 items for subjects' general characteristics, 18 items for job satisfaction measurement, and 7 items for social support measurement. An analysis of the collected data was computationally processed by using SPSS Win 17.0 program. An analytical technique was made by using statistical techniques such as frequency & percentage, T-test or One-way ANOVA analysis. The following are the analytical results of the collected materials. Results: As a result of analyzing research subjects' job satisfaction level, there was significant difference(P<0.05) in items of religion, hobby life, working environment, and rest time out of daily work. The whole mean in job satisfaction was indicated to be relatively high with 3.13. However, job satisfaction with social recognition, salary, and safety was indicated lowly. As a result of analyzing research subjects' social support level, there was significant difference(P<0.05) in items of age, working environment, and rest time out of daily work. The whole mean in social support was indicated to be relatively high with 3.49. As a result of analyzing correlation between job satisfaction and social support, all variables were indicated to be positive correlation in high significance level, thereby having been indicated that the higher job satisfaction leads to the higher social support. Conclusion: As a result of this study, there is high correlation between social support and job satisfaction. An effort and a support are considered to be necessary for forming positive personal relations among members such as relationship with family member and with fellow employee, for improving the working conditions, and for enhancing dental technicians' pride and social recognition in order to promote dental technician's job satisfaction.

Study of Cosmeceutical Activities of Hovenia dulcis var. koreana Nakai Extracts (헛개나무 추출물의 화장품 생리활성에 관한 연구)

  • Kim, Sea-Hyun;Jun, Dong-Ha;Jang, Min-Jung;Lee, Jin-Tae;Lee, Chang-Eon;Han, Jin-Gyu;Kim, Jin-Chul;Lee, Do-Hyung
    • Journal of Korean Society of Forest Science
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    • v.99 no.6
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    • pp.836-842
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    • 2010
  • Hovenia dulcis var. koreana Nakai has been reported to liver function improvement effect as functional materials for food and medicine. On these facts, biological activity and safety test were conducted to evaluate biological activities of the fruit petiole and root extracts of H. dulcis as a potential cosmeceutical ingredient. Cosmeceutica activities of different extracts were examined by l.l-diphenyl-2-picrylhydrazyl (DPPH) radical generation, the ABTS+ cation decolorization, tyrosinase activity, collagenase activity and elastase activity compared with the properties of the commercial antioxidant butylated hydroxytoluene (BHT) and L-ascorbic acid (AA). The antioxidant activities HDFW, HDFE, HDRW and HDRE were 83.6%, 39.6%, 85.9% and 74.5% in DPPH assay, 99.5%, 13.7%, 96.4% and 88.6% in ABTS assay. Tyrosinase inhibitiory activities HDFW were 56.0% at 1,000 ppm. Measured the inhibition effect of the H. dulcis about collagenase and elastase where break the peptide bonds in collagen and enzyme from the class of proteases where exists in the dermis. The H. dulcis was inhibition the two kind enzymesm, collagenase activities being on a high scale inhibition, was same concentration. Uses the anti oxidation effect and a anti-wrinkle effect of this resultant H. dulcis and with the functional cosmetics use is thought with the fact that will be possible.

Genotoxicological Safety Evaluation of X-ray Irradiated Four Foods (X-선 조사식품 4종의 유전독성학적 안전성 평가)

  • Jung, Da-Woon;Huang, Yu-Hua;Song, Beom-Seok;Byun, Myung-Woo;Kang, Il-Jun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.10
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    • pp.1588-1593
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    • 2014
  • This study evaluated the genotoxic effects of 30 kGy of X-ray irradiation to four foods (chicken, egg powder, dried green onion, and black pepper). In bacterial reversion assay with Salmonella Typhimurium TA98, TA100, TA1535, and TA1537, the X-ray irradiated foods did not show a significantly increased number of revertant colonies in the presence or absence of the S9 metabolic activation system. In chromosomal aberration tests with Chinese hamster ovary (CHO) cells, the X-ray irradiated foods showed no increase in the frequency of chromosomal aberrations. In in vivo mouse micronucleus assay, the X-ray irradiated foods did not show any increase in the frequency of polychromatic erythrocytes with micronuclei. These results indicate that 30 kGy of X-ray irradiation to four foods (chicken, egg powder, dried green onion, and black pepper) showed no genotoxic effects under these experimental conditions.