• 제목/요약/키워드: Safety serve

검색결과 350건 처리시간 0.032초

Introduction of Vaccinomics to Develop Personalized Vaccines in Light of Changes in the Usage of Hantaan Virus Vaccine (Hantavax®) in Korea

  • Bae, Jong-Myon
    • Journal of Preventive Medicine and Public Health
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    • 제52권5호
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    • pp.277-280
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    • 2019
  • The Ministry of Food and Drug Safety of Korea made an official announcement in March 2018 that the total number of inoculations of Hantaan virus vaccine ($Hantavax^{(R)}$) would change from 3 to 4. Some aspects of this decision remain controversial. Based on the characteristics of Hantaan virus (HTNV) and its role in the pathogenesis of hemorrhagic fever with renal syndrome, it might be difficult to develop an effective and safe HTNV vaccine through the isolate-inactivate-inject paradigm. With the development of high-through-put 'omics' technologies in the 21st century, vaccinomics has been introduced. While the goal of vaccinomics is to develop equations to describe and predict the immune response, it could also serve as a tool for developing new vaccine candidates and individualized approaches to vaccinology. Thus, the possibility of applying the innovative field of vaccinomics to develop a more effective and safer HTNV vaccine should be considered.

청정수소 인증제 시행방안 연구 (A Study on Implementation Plan of Clean Hydrogen Certification System)

  • 이한우;김진호
    • 한국수소및신에너지학회논문집
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    • 제33권4호
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    • pp.301-308
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    • 2022
  • The Hydrogen Economy Promotion and Hydrogen Safety Management Act (hereinafter referred to as the "Hydrogen Economy Act") stipulates matters related to certification and cancellation of clean hydrogen by grade, and requires those who produce, import, or sell clean hydrogen to report to the Minister of Trade, Industry and Energy. In order for this system to operate smoothly, the clean hydrogen Certification system must be designed to meet international standards, and the institution operating the System must have appropriate capabilities and foundations. The clean hydrogen certification system should serve as an opportunity for Korea's domestic energy industry to take a leap forward.

Neutron spectrum unfolding using two architectures of convolutional neural networks

  • Maha Bouhadida;Asmae Mazzi;Mariya Brovchenko;Thibaut Vinchon;Mokhtar Z. Alaya;Wilfried Monange;Francois Trompier
    • Nuclear Engineering and Technology
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    • 제55권6호
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    • pp.2276-2282
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    • 2023
  • We deploy artificial neural networks to unfold neutron spectra from measured energy-integrated quantities. These neutron spectra represent an important parameter allowing to compute the absorbed dose and the kerma to serve radiation protection in addition to nuclear safety. The built architectures are inspired from convolutional neural networks. The first architecture is made up of residual transposed convolution's blocks while the second is a modified version of the U-net architecture. A large and balanced dataset is simulated following "realistic" physical constraints to train the architectures in an efficient way. Results show a high accuracy prediction of neutron spectra ranging from thermal up to fast spectrum. The dataset processing, the attention paid to performances' metrics and the hyper-optimization are behind the architectures' robustness.

Advance Crane Lifting Safety through Real-time Crane Motion Monitoring and Visualization

  • Fang, Yihai;Cho, Yong K.
    • 국제학술발표논문집
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    • The 6th International Conference on Construction Engineering and Project Management
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    • pp.321-323
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    • 2015
  • Monitoring crane motion in real time is the first step to identifying and mitigating crane-related hazards on construction sites. However, no accurate and reliable crane motion capturing technique is available to serve this purpose. The objective of this research is to explore a method for real-time crane motion capturing and investigate an approach for assisting hazard detection. To achieve this goal, this research employed various techniques including: 1) a sensor-based method that accurately, reliably, and comprehensively captures crane motions in real-time; 2) computationally efficient algorithms for fusing and processing sensing data (e.g., distance, angle, acceleration) from different types of sensors; 3) an approach that integrates crane motion data with known as-is environment data to detect hazards associated with lifting tasks; and 4) a strategy that effectively presents crane operator with crane motion information and warn them with potential hazards. A prototype system was developed and tested on a real crane in a field environment. The results show that the system is able to continuously and accurately monitor crane motion in real-time.

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한시적 스트리트 퍼니처의 사례와 특성에 관한 연구 - 공사장 가설울타리와 가림막을 대상으로 - (Research on Characteristics and Actual Cases of Temporary Street Furniture -Focused on the Tentative Construction and Screen Fences at Construction Sites-)

  • 배현미
    • 한국가구학회지
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    • 제20권1호
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    • pp.21-30
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    • 2009
  • This research is conducted on temporary street furniture, which is one of the significant factors that comprise the street landscape in modem cities. The primary purpose of this research is to present the guidance on direction of planning by examining the design and installation types of construction and screen fences usually established at construction sites for buildings, roads, parks and etc. The results are as follows: 1. The construction and screen fences at construction sites of urban areas used to be a mere tentative facility to prevent noise and safety accidents but have now incremented their roles to serve not only as a functional but also as an aesthetic element with a city view and harmonization with other elements taken into consideration. In particular, it is noticeable that, based on its unique feature of tentativeness, its role has developed to serve as street furniture that adds variability to the modem city. 2. There are two different types of screen fences: blackout type and transparent type. The transparent screen turns out to be used a lot at the construction site of building a skyscraper or differentiated building in downtown city area or in places where there are buildings of similar types and shapes located along the street in the vicinity of the construction site. 3. The actual cases of adopting the tentative construction and screen fences all at the same time as a single unit have been found in historically and culturally significant architectures with the screen design used to demonstrate the view after completion of construction or the characteristics of the architecture.

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병원급식에서 Ready-Prepared Foodservice System 이용에 관한 연구 (A study for the utilization of ready-prepared foodservice system concept to the Korean hospital foodservice operations)

  • 김지영;김혜영
    • 한국식품조리과학회지
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    • 제2권2호
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    • pp.21-31
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    • 1986
  • Here is a research on hospital foodservice system, when korea traditional food of pyeon yuk and bin dae deok were used by ready-prepared foodservice system, it was estimated the preservations of microbiological quality and sensory quality. All data collection was replicated three times. The results were as following; 1. In time and temperature data, two menu items were needed internal temperature below $7^{\circ}C$ in a cooling stage, and in the case of cook/chill storage, the days were shortened within weeks, and the holding time must be possiblely minimized. Finally foods were served sanitary. 2. In view of microbiological safety, in the case of cook/chill storage as $0{\sim}4^{\circ}C$ the days must be shortened within 2 weeks and its was possible to store until 6 weeks in $-20{\sim}-23.3^{\circ}C$. So to preserve pre-cooked food longly, it was effective to freeze them quickly by using vacuum package and to reheat them by a microwave oven before serving and to serve lastly in microbiological quality. 3. Hospital ready-prepared foodservice system with food storage in plastic bags, biochemical test of C. Perfingens C. botulinum and Salmonella were not detected. 4. By using of a microwave oven, it had effects of thawing, reheating and sterilizing of chilled and frozen foods in a short time. 5. Sensory evaluations were made by a 10-member panel using five scoring tests. Because sensory of quality was lowered in the case of chilled storage, it was possible to serve foods within 2 weeks. Texture and aroma were preserved by cook/frozen system and usually there was no significance from 4 weeks until 6 weeks, but considering of the objects, it was good to store until 4 weeks in sensory quality.

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Application of Sequence Diagrams to the Reverse Engineering Process of the ESf-ccs

  • Hasan, Md. Mehedi;Elakrat, Mohamed;Mayaka, Joyce;Jung, Jae Cheon
    • 시스템엔지니어링학술지
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    • 제15권1호
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    • pp.1-8
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    • 2019
  • Reverse engineering involves examining a system or component so as to comprehend its structure, functionality, and operation. Creation of a system model in reverse engineering can serve several purposes: test generation, change impact analysis, and the creation of a new or modified system. When attempting to reverse engineering a system, often the most readily accessible information is the system description, which does not readily lend itself to use in Model Based System Engineering (MBSE). Therefore, it is necessary to be able to transform this description into a diagram, which clearly depicts the behavior of the system as well as the interaction between components. This study demonstrates how sequence diagrams can be extracted from the systems description. Using MBSE software, the sequence diagrams for the Engineered Safety Features Component Control System (ESF-CCS) of the Nuclear Power Plant are created. Sequence diagrams are chosen because they are a means of representing the systems behavior and the interaction between components. In addition, from these diagrams, the system's functional requirements can be elicited. These diagrams then serve as the baseline of the reverse engineering process and multiple system views are subsequently be created from them, thus speeding up the development process. In addition, the use of MBSE ensures that any additional information obtained from auxiliary sources can then be input into the system model, ensuring data consistency.

남성 근로자의 생식보건 역학연구 (Epidemiologic Studies of Reproductive Health in Male Workers)

  • 최병주;이상길;김성규;성정민;예신희
    • 한국산업보건학회지
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    • 제31권3호
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    • pp.202-212
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    • 2021
  • Objectives: The reproductive health of female workers has been extensively investigated in South Korea and other countries worldwide. However, few studies have discussed the reproductive health of male workers. In this study, we reviewed the recent literature that reports on the effects of occupational exposure on the reproductive health of male workers and the health of their children. Methods: In May 2020 we used the PubMed search engine to search the literature over the last 10 years and chose case-control, cohort, and cross-sectional studies and reviews. We selected epidemiological studies that investigated the association between pre-pregnant occupational exposure and the reproductive health of male workers and the health of their children. We excluded case reports, non-epidemiological studies (animal experiments, cellular-level experiments, and similar articles), and studies that described postnatal occupational exposure. Results: We eventually selected 23 studies. The studies that included exclusively male workers reported that those employed in the agricultural sector or those exposed to pesticides showed lower blood levels of reproductive hormones and a high risk of lympho-hematopoietic system cancer in their children. Male workers exposed to complex organic solvents and organic compounds showed a high risk of poor semen quality, increased time to pregnancy, decreased blood levels of reproductive hormones, and a high risk of lympho-hematopoietic system cancer in their children. Male workers employed in occupations that involved significant social contact, or in the leather and livestock industries, and in occupations with high levels of exposure to lead and organic solvents showed a high risk of malignancies, including lympho-hematopoietic system cancer, neuroblastoma, and central nervous system tumors in their children. Studies that investigated both male and female workers reported that children of male smelters showed a high risk of premature birth, and children of male workers exposed to metals showed a high risk of hypospadias and cryptorchidism. Children of male welders and workers employed in the glass, ceramic, and tile industries showed a high risk of premature birth. Conclusion: The findings of this study will serve as basic data for further research on male workers' reproductive health and provide a scientific basis for the development of strategies to protect the reproductive health of males employed in high-risk occupations. Moreover, the results of this study may provide guidelines to improve the understanding of and knowledge on male workers' reproductive health.

AHP 기법 기반 진해만 태풍 피항지 내 안전대책에 관한 연구 (A Study on the Safety Measures for Typhoon Shelter in Jinhae Bay Based on AHP Assessment)

  • 김니은;이명기;교칸 참르율트;박도형;김대원;박영수
    • 해양환경안전학회지
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    • 제28권4호
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    • pp.507-514
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    • 2022
  • 진해만 해역은 태풍 내습 시에 우리나라 남동권 해역의 주요 태풍 피항지로 이용되고 있다. 하지만 태풍 내습 시 진해만 내 선박이 폭주하고 주묘가 다수 발생하는 등 해양사고 발생 가능성이 존재한다. 본 논문은 태풍 내습 시 진해만 피항지에 대해 안전 확보 및 효율적으로 관리할 수 있는 방안을 해당 해역의 VTS 관제사로부터 도출하고, 이를 선박 운항자에게 AHP 기법을 통하여 상대적 중요도를 도출하여 관리자와 이용자 의견이 반영된 안전대책을 제시하였다. AHP 설문조사를 위한 안전 대책 요소를 선정하기 위하여 진해만 내 태풍 내습 시 VTS 관제사의 대응 조치 평가 내용에 대해 분석하였다. 선정된 안전대책 요소를 기반으로 설문조사를 실시한 결과, 선정된 요소에 대해 선박 운항자는 선박의 안전을 효율적 관리보다 약 2배 이상 중요하게 생각하며, 종합적으로 피항선 관리, 정박구역 관리, 피항정보 관리, 규정 및 지침 마련, 시스템 장비 개선, 교육 및 홍보·알림 활동 순으로 중요하게 고려함을 파악하였다. 본 논문에서 식별된 방안 및 상대적 중요도를 통해서 진해만 태풍 피항지를 안전하고 효율적으로 관리하는 기반이 될 수 있을 것으로 사료된다.

LC-MS/MS를 이용한 농산물 중 Streptomycin 및 Dihydrostreptomycin 동시시험법 개발 (Development of Simultaneous Analytical Method for Streptomycin and Dihydrostreptomycin Detection in Agricultural Products Using LC-MS/MS)

  • 이한솔;도정아;박지수;박신민;조성민;신혜선;장동은;최영내;정용현;이강봉
    • 한국식품위생안전성학회지
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    • 제34권1호
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    • pp.13-21
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    • 2019
  • 본 연구는 2018년 국내식품 중 신규 기준설정 예정 농약인 스트렙토마이신의 잔류 농약 검사를 위한 공정시험법을 마련하기 위하여 수행하였다. 스트렙토마이신은 아미노글리코사이드계 항생제로 소, 돼지, 닭 등 가축 및 가금에 동물용의약품으로 허가되어 세균성 질병치료에 사용되고 있다. 또한 우리나라에서는 감귤, 매실, 참다래, 복숭아 등에 발병하는 세균성 병해를 방지하기 위하여 농약으로 등록되어 있다. 국내에서는 스트렙토마이신의 잔류물의 정의를 스트렙토마이신과 디히드로스트렙토마이신의 합으로 정하여 관리하고 있으며 잔류허용기준은 동물용의 약품으로 사용 시 불검출부터 1.0 mg/kg까지 설정되어 있다. 농약으로 사용 시 농산물 중 잔류허용기준은 설정되어 있지 않으며 식품공전의 시험법 역시 동물용의약품에 적용되는 시험법으로 설정되어 있다. 이에 농산물 중 잔류허용기준 설정을 위한 시험법 마련이 시급하여 본 연구에서는 식품공전에서 정하고 있는 대표농산물 5종(현미, 감자, 대두, 감귤, 고추)을 포함한 잔류시험법을 개발하고자 하였다. 따라서 수용성 유기용매인 메탄올의 적용과 포름산을 이용한 pH 조절을 통한 추출법 및 HLB 카트리지를 이용한 정제법을 최적화하여 LC-MS/MS에 의한 분석법을 확립하였다. 스트렙토마이신과 디히드로스트렙토마이신의 시험법 정량한계는 0.01 mg/kg으로 PLS 제도에 맞는 잔류허용기준 수준을 만족하였다. 스트렙토마이신과 디히드로스트렙토마이신의 평균 회수율은 각각 72.0~116.5%와 72.1~116.0%이었고, 상대표준편차는 각각 12.3%와 12.5% 이하로 조사되어 이러한 결과는 국제식품규격위원회 가이드라인(CAC/GL 40-1993, 2003)의 잔류농약 분석기준 및 식품의약품안전평가원의 '식품등 시험법 마련 표준절차에 관한 가이드라인(2016)'에 적합한 수준임을 검증하였다. 따라서 본 연구에서 개발한 시험법은 농산물 중 스트렙토마이신의 잔류검사를 위한 공정시험법으로 활용할 수 있으며 유사 농산물에 대한 적용도 가능하리라 판단되어 향후 국내 농산물 중 농약의 잔류허용기준 신설 및 잔류농약 검사의 기초자료로 활용 가능할 것이다.