• Asian-Australasian Journal of Animal Sciences
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• v.32 no.6
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• pp.834-841
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• 2019

Objective: This study was conducted to investigate the effects of in ovo feeding (IOF) of creatine pyruvate (CrPyr) on the energy metabolism in thigh muscle of embryos and neonatal broilers. Methods: A total of 960 eggs were randomly assigned to three treatments: i) non-injected control group, ii) saline group injected with 0.6 mL of physiological saline (0.75%), and iii) CrPyr group injected with 0.6 mL of physiologi-cal saline (0.75%) containing 12 mg CrPyr/egg on 17.5 d of incubation. After hatching, 120 male chicks (close to the average body weight of the pooled group) in each group were randomly assigned to eight replications. The feeding experiment lasted 7 days. Results: The results showed that IOF of CrPyr increased glucose concentrations in the thigh muscle of broilers on 2 d after injection (p<0.05). Compared with the control and saline groups, the concentration of creatine in CrPyr group was increased on 2 d after injection and the day of hatch (p<0.05). Moreover, IOF of CrPyr increased the creatine kinase activity at hatch and increased the activities of hexokinase and pyruvate kinase on 2 d after injection and the day of hatch (p<0.05). Chicks in CrPyr group showed higher mRNA expressions of glucose transporter 3 (GLUT3) and GLUT8 on the day of hatch (p<0.05). Conclusion: These results demonstrated that IOF of CrPyr was beneficial to enhance muscle energy reserves of em-bryos and hatchlings.

• Journal of the Korean Society of Safety
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• v.31 no.4
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• pp.156-163
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• 2016

There exists required safety integrity level (SIL) to assure safety in accordance with international standards for every electrical / electronics / control equipment or systems with safety related functions. The SIL is allocated from lowest level (level 0) to highest level (level 4). In order to guarantee certain safety level that is internationally acceptable, application of methodology for SIL allocation and demonstration based on related international standards is required. However, the theoretical and practical study for safety integrity level is barely under way in the domestic railway industry. This research studied not only the global process of SIL allocation to guarantee safety in accordance with international standards for safety related equipment and system, but the quantitative methodology based on international standard and the semi-quantitative methodology as alternative way for SIL allocation. Specifically, the systematic SIL allocation for platform screen door system of railway is studied applying the semi-quantitative methodology in order to save much time and effort compared to quantitative method.

• Journal of the Korean Society of Safety
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• v.30 no.6
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• pp.164-173
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• 2015

There exists required safety integrity level (SIL) to assure safety in accordance with international standards for every electrical / electronics / control equipment or systems with safety related functions. The SIL is allocated from lowest level (level 0) to highest level (level 4). In order to guarantee certain safety level that is internationally acceptable, application of methodology for SIL allocation and demonstration based on related international standards is required. However, application standard differs from every industry in domestic or international for application on mythology for allocation and demonstration of SIL. Application or assessment is not easy since absence on clear criteria or common definition. This research studied not only fundamental concept of SIL required to guarantee safety in accordance with international standards for safety related equipment and system, but different types of methodologies for SIL allocation. Specifically, SIL allocation for Platform Screen Door system of railway is studied applying methodology of severity of accidents and risk graph among different methodologies for SIL allocation.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.12
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• pp.2008-2020
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• 2020

Objective: This study was conducted to investigate the effects of dietary corn resistant starch (RS) on the intestinal morphology and barrier functions of broilers. Methods: A total of 320 one-day-old broilers were randomly allocated to 5 dietary treatments: one normal corn-soybean (NC) diet, one corn-soybean-based diet supplementation with 20% corn starch (CS), and 3 corn-soybean-based diets supplementation with 4%, 8%, and 12% corn resistant starch (RS) (identified as 4% RS, 8% RS, and 12% RS, respectively). Each group had eight replicates with eight broilers per replicate. After 21 days feeding, one bird with a body weight (BW) close to the average BW of their replicate was selected and slaughtered. The samples of duodenum, jejunum, ileum, caecum digesta, and blood were collected. Results: Birds fed 4% RS, 8% RS and 12% RS diets showed lower feed intake, BW gain, jejunal villus height (VH), duodenal crypt depth (CD), jejunal VH/CD ratio, duodenal goblet cell density as well as mucin1 mRNA expressions compared to the NC group, but showed higher concentrations of cecal acetic acid and butyric acid, percentage of jejunal proliferating cell nuclear antigen-positive cells and delta like canonical Notch ligand 4 (Dll4), and hes family bHLH transcription factor 1 mRNA expressions. However, there were no differences on the plasma diamine oxidase activity and D-lactic acid concentration among all groups. Conclusion: These findings suggested that RS could suppress intestinal morphology and barrier functions by activating Notch pathway and inhibiting the development of goblet cells, resulting in decreased mucins and tight junction mRNA expression.

• Journal of Information Processing Systems
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• v.14 no.2
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• pp.309-321
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• 2018

In the conventional computing environment, users use only a small number of software systems intensively. So it had been enough to check and guarantee the functional correctness and safety of a small number of giant systems in order to protect the user systems and their information inside the systems from outside attacks. However, checking the correctness and safety of giant systems is not enough anymore, since users are using various software systems or web services provided by unskilled developers. To prove or guarantee the safety of software system, a lot of research has been conducted in diverse areas of computer science. We will discuss the on-going approaches for guaranteeing or verifying the safety of software systems in this paper. We also discuss the future research challenge which must be solved with better solutions in the near future.

• Proceedings of the KSR Conference
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• 2006.11b
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• pp.1508-1513
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• 2006

Currently, the Korean railway safety law (RSL) and its ordinances have been enforced for the guarantee of the safety of railway. In RSL, the quality certification is required to guarantee the safety and performance of railway components or systems. However, not much attention has been focused on the quality certification scheme for railway components or systems since the scheme is relatively new. Therefore, in this investigation, the detailed guidelines and main contents for the enforcement of quality certification for railway components will be suggested, and the detailed items including the procedures, subjects, management, etc., will be addressed. Moreover, a better understanding on quality certification for railway components will be provided.

• Proceedings of the KSR Conference
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• 2008.11b
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• pp.1113-1125
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• 2008

In this paper we present a RAMS to be applied to the development of the Urban Maglev Train Signalling System. The RAMS that can be applied to the life cycle of a Signalling system, from the basic design to the dismantlement, shows the whole process of the paper work in detail through the establishment of a goal, analysis and assessment, the verification. In this paper we study about the making a plan, the preliminary hazard analysis, the hazard identification and analysis to guarantee the safety of the Signalling System. The process for the verification of the system safety is divided into several steps based on the target system and the approaching method. The guarantee of the system safety and the improvement of the system reliability is followed by the recommendation of the international standards.

• Journal of Navigation and Port Research
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• v.40 no.1
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• pp.21-26
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• 2016

Even in the marine industry was required the looser positioning performance as compared to other application domain, a high-quality positioning performance and reliability are becoming ever more important. The high-quality performance includes not only accuracy but also integrity, continuity, and availability. However, current DGPS service is not satisfying the minimum positioning performance requirements for maritime user proposed by IMO. Especially, no one can guarantee the required integrity performance by DGPS service. This paper presents the advanced monitoring concept to strengthen the performance of current DGPS through the enhanced monitoring, guarantee and notice functions. To this, the limitations of the integrity monitoring function of current DGPS are analyzed, and a countermeasure is prepared to improve the limitations of the current integrity monitoring function. This paper can be applied as basis research to improvement of the DGPS service.

• International Journal of Railway
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• v.2 no.3
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• pp.113-117
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• 2009

Risk management is an important part of system assurance and it is widely used in safety-related system. Railway signal system is one kind of safety-related system and its most important goal is to guarantee the safety of railway system. The method based on risk management can find and solve the security issues of railway signal system more effectively. This paper introduces the basic conception of risk management, studies the whole process of risk management and related tools and techniques and discusses some key points qualitatively combining with the particularity of railway signal system.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.2557-2562
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• 2011

The purpose of Overall Railroad Safety Audit(ORSA) is to prevent railroad accidents, and, every two years, to inspect and evaluate whether or not railroad operators faithfully adhere to railroad safety guidelines in accordance with the Railroad Safety Law. However despite of the many contributions of ORSA, due to lots of railroad accidents such as train failures and derailment caused track irregularity this year, it has been recently considered that ORSA will be renewed into Safety Certificates System as a complement. In order to guarantee railroad safety, new Safety Certificates must included appropriate safety standards considering current our country's railroad conditions. Therefore, in this study we're going to compare safety components of foreign audit system with those of Airlines field, based on ORSA's contents for years, to review Safety Management System and Safety Culture, as a result, we'd like to suggest to updated Railway Safety Standards.