Park, Woo-Young;Bae, Chun-Sik;Lee, Soo-Han;Park, Woo-Dae
Journal of Veterinary Clinics
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v.26
no.3
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pp.212-219
/
2009
Anticholinergics, which are commonly given as a pre-anesthetic medication to prevent adverse effects in canine anesthesia, can cause cardiac adverse effects. To determine the effects of atropine and glycopyrrolate on the balance of sympathetic nervous tone and parasympathetic nervous tone of the heart during ketamine anesthesia in beagle dogs, heart rate variability(HRV), duration of anesthesia and behavioral changes were evaluated. There were no significant temporal domain differences between atropine and glycopyrrolate. Concerning the frequency domain component, atropine and glycopyrrolate effects were significantly lower(P<0.05) than the control saline-treated group. However, the root mean square of the interval differences between consecutive R peaks(RMSSD) and the standard deviation of Poincare plot perpendicular to the line-of-identity(SD1) in atropine were significantly decreased(P<0.05) from the baseline value, and the low frequency/high frequency ratio(LF:HF ratio) in glycopyrrolate was significantly increased from baseline value(P<0.05). The change of SD1 agreed with that of the high frequency(HF) in the frequency domain component and also with those of respiratory rate and $SpO_2-R$. Our results prove that glycopyrrolate is more suitable as a pre-anesthetic anticholinergic in ketamine anesthesia of dogs with respect to safety and duration of action.
The electromagnetic valve of pneumatic doors of EMUs has a high failure rate due to air leakage because it supplies air on and off to operate the doors repeatedly. The electromagnetic valve is a very important safety component for which a very high reliability is required because failure makes it impossible to operate the passenger cars. However, domestic urban railway operators maintain electronic valves of the EMU door under a fixed cycle with a spare period according to the full overhaul cycle of the EMU. An improvement of the current maintenance cycle was suggested based on the reliability function and mission reliability. Using the statistical program MINITAB for the operational data of EMU line 6, we analyzed the characteristics of the fault distribution and derived the shape and scale parameters of the reliability function. If we limit the specific reliability probability to under a certain failure rate and calculate its statistical parameters, we can calculate the allowable inspection period with mission reliability. Through this study, we suggested a maintenance period based on RCM (reliability centered-maintenance) to improve the reliability of electromagnetic valves from 68% to 95%.
During maintenance or construction works in or at the tracks of railways, high risks for passengers and railway staff, especially for the workers on the construction site exist. The high risks result out of the movement of rail vehicles, like trains or construction vehicles, which must be faced by using any available technical and operational technologies for securing them against the environment. Therefore, it is necessary to evaluate the level of protection continuously and to identify new and innovative methods and technologies for the protection of the gang (construction worker, machines and material). Especially on construction sites at line sections with two or more parallel tracks but also with single tracks, there are still a lot of incidents and accidents mostly with seriously injured persons or fatalities. These were mainly gang members that breach the railway-loading gage. By using proper warning or protection systems, the avoidance of such accidents must be achieved. The latest developments. in gang protection systems concern on the one hand fixed barriers in the middle between the construction site and the operated track and on the other hand construction vehicles equipped with automatic warning systems. The disadvantage of such protection methods is that the gang can be warned against an approaching train but a monitoring of the gang members cannot be performed. Only one part of a potential dangerous situation will be detected. If the gang members will overhear the acoustic warning signal of the security staff and the workers will not leave the danger zone in the track, the driver of the approaching train had no chance to react to the dangerous situation. An accident is often inevitable. While the detection of acoustic warning signals by the gang members working on a construction site is very difficult, the acoustical planning of an automatic warning system has to be designed for an acoustic short range level of one meter besides the construction vehicle. The decision about the use of today's technical warning system (fixed systems, automatic warning systems, etc.) must be geared to the technical feasibility and the level of safety which is needed. Criteria for decision guidance to block a track should be developed by danger estimation and economical variables. To realize the actual jurisdiction and to minimize the hazards of railway operations by the use of construction vehicles near the tracks further developments are needed. This means, that the warning systems have to be enhanced to systems for protection, which monitor the realization of the warning signal as a precondition for giving a movement authority to a train. This method can protect against accidents caused by predictable wrongdoing. The actual state of the art technique of using a collective warning combined with additional security staff is no longer acceptable. Therefore, the Institute of Transportation System of the German Aerospace Center in Braunschweig (Germany) will develop a gang warning and protection system based upon imaging methods, with optical sensors such as video in visible and invisible ranges, radar, laser, and other. The advantage of such a system based on the possibility to monitor both the gang itself and the railway-loading gauge either of the parallel track or of the same track still in use. By monitoring both situations, the system will be able to generate a warning message for the approaching train, that there are obstacles in the track, so that the train can be stopped to prevent an accident. And also the gang workers will be warned, while they breach their area.
Proceedings of the Korean Institute Of Construction Engineering and Management
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2007.11a
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pp.995-998
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2007
The number of households old over as much as 20 years is expected to get increased rapidly more than 1,000,000(1 million). As a measure to this fact remodeling is being revitalized over the country. parking lots expansion actually takes up a great deal of weight among the requirement for remodeling. When constructing a parking lot for enlargement, the way of going into the main building determines such construction features as selection of Retaining Wall Method, installation of an elevator, parking measure of capacity, etc. This study derived the affecting factors for selecting the way of going into the main building when constructing an underground parking lot. In a research way, we examined the features on each method of going into the main building in an apartment complex through an in-depth interview with some experts after investigating the method of enlarging an underground parking lot and going into the main building. After that, we derived the affecting factors for selecting the way of going into the main building. The affecting factors include constructability, convenience, economic efficiency as a high level as well as existence and nonexistence of basement and removal, safety of current building, parking measure of capacity, amenity, inhabitant traffic line, construction expenses and construction duration as a low one. This study will be applied as a reference for selecting the way of going into the main building when constructing an underground parking lot especially targetted on an old apartment house.
Journal of the Economic Geographical Society of Korea
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v.10
no.2
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pp.137-152
/
2007
This paper aims to clarify the types of cities by automobile traffic accidents and to search the characteristics of automobile traffic accidents for each type. Cities by automobile traffic accidents are classified into 4 types. Seoul city belongs to Type A in which 'automobile use and accident type' is closely related. Osan city belongs to Type B where the number of automobile traffic accidents is the greatest. And many satellite cities of Seoul city and metropolitan cities, and cities distributed in Southeastern industrial region belongs to Type C in which automobile accidents are fewer than the national average. Other 57 cities belongs to Type D which there are more automobile accidents than the national average. The cause of traffic accidents for each city type are as follows. In Seoul city the major causes of accidents are no security of safety distance, road patterns of other region, and injury of pedestrians. In Osan city, many single lane road accidents, central line invasion, and traffic accidents of children of under 14 years. And in satellite cities of Seoul city and metropolitan cities, and cities distributed in Southeastern industrial region, the major causes are traffic regulation violation, of under 6m in crossroad accidents, accident of children of under 14 years, and injury of pedestrians. Lastly, in other 57 cities chief causes are traffic regulation violation, wrong methods of passing crossroads, injury of children of under 14 and elderly of over 61 years, and injury of pedestrians.
Ji, Younghwan;Kim, Kihwan;Kim, Sungho;Hwang, Yeongcheol;Lee, Seungho
Journal of the Korean GEO-environmental Society
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v.11
no.12
/
pp.47-56
/
2010
The construction of new roads and the consistent extension of already-existing roads or the line-shape revision of those roads are increased with the governmental investment to SOC facilities currently. Accordingly, the road cut slopes are in the trend of rapidly increasing. As the road slope has increased, a lot of human and property damages has entailed consequently and in the local case, numerous studies have carried out aiming at minimizing this damages caused by the rockfall and landslide. In general, standard falling rock prevention facility has employed for most of the local road slope based on "Guide for Installation and Management of Road Safety Facilities" published by MLTM(the Ministry of Land, Transport, and Maritime Affairs) but profound doubt has raised as to whether this rockfall prevention facility would function properly enough to prevent rockfall efficiently without any damages in case of actual occurrence of rockfall. In addition, it is a reality that in most cases, such work is relied on overseas technology as a whole as the local technical level is low and in case of rockfall prevention net, it is judged that a study on rockfall prevention net that is able to endure more powerful rockfall energy is required as the problem including net bursting is taken place as a result of enough bearing force being failed to be demonstrated due to its partial weak point(not uniformly made). Under this background, in this study, three kinds of model depending on mesh size of expanded metal that is considered to have an adoptability as rockfall prevention net, as target are selected and characteristics depending on mesh size of expanded metal is intended to be researched through a pull-out test performance by using pull-out test equipment rockfall prevention net.
Compressed Natural Gas (CNG) buses have been supplied since the year 2000 in order to resolve severe atmospheric pollution in metropolitan area and contributed on the improvement of urban atmospheric environment. However, it is indispensible to take an adequate measure to guarantee the safety of CNG vehicles because of the possibility of huge fire accident. A receptacle, connecting device between high pressure fuel supply tank and fuel line, plays an important role in CNG supply system. In recent, leakage of CNG from receptacles has been reported. So, the concern about the security and reliability of receptacles has been arisen. Therefore, a lot of efforts to prevent leakage are invested among researchers and the durability of this component should be guaranteed despite repeated operation. This research has performed durability tests of a CNG receptacle regarding the repeated usage, extreme chattering, and continuous full flow test. Although a receptacle used for CNG vehicle satisfies validation requirements in the test results, it has been found that failure in the function of leakage prevention in a receptacle could take place in the case of prolonged exposure to high supply pressure in common quick charging environment on site.
This research examines the effect of area level characteristics on individual health, particularly focusing on the vulnerable populations in Seoul. We consider adult individuals whose family income is under 1.5 million won, who are aged 65 and over, or who have neither spouse nor job but aged 40 and over as vulnerable populations. Using the 2005 Seoul Citizens' Health Interview Survey, we conducted multilevel analyses to simultaneously investigate the effect of area and individual level characteristics on health. Between-area variance of self-rated health status was greater for the elderly population than for all populations. Area material deprivation index and happiness index were associated with the self-rated health of economically disadvantaged populations. Vulnerable populations showed greater between-area variances in emotional health than the same for all populations. Area happiness index, material deprivation index, the proportion of households below poverty line and street safety showed statistically significant association with emotional health. The effect of area characteristics were particularly salient for the emotional health of elderly population and its between area variance was also notable.
Objectives : NK cells are spontaneously cytotoxic lymphocytes. These are not only important parts in the first line of defence against bacterial and viral infections of outside, but they may also play a critical role in chronic viral diseases. NK cells kill their targets spontaneously, without the need for prior sensitization and class I MHC restriction by the regulation of cytolytic functions and secretion of a variety of cytokines, such as interleukin-12(IL-12), MCP-1, IL-6, TNF-${\alpha}$, IFN-${\gamma}$. In addition, macrophage and NK cells cooperate through the production of cell mediates. These cooperation and modulation are one of major factors to prevent for evading immune surveillance of cancer. Hence, it could be assumed that if any candidate to enhance activities of macrophage and NK cell, it is considered as a potentially useful agents against cancer. Methods : In our study, to investigate effect of fermented soybean extracts by Lactic acid bacteria (SFE, soybean fermented extracts) work on intestinal immune cell to maintain general immune modulating and anti-cancer activity. We analyzed NK cytotoxicity assay and gene expressions of cytokine related with macrophage and NK cell activity. Results : In vitro experiment, SFE was verified as safety material for cell toxicicty to tumor cell strain without any toxicity of tumor growth inhibition and various cell strain. Effects of macrophage activity stimulating directly by SFE measured induced cytokine. The studies showed that IL-12 production by stimulation of SFE depended on concentration from 0.16mg/mL to 0.63mg/mL with non toxicity to cell, and it was the best activity at 0.63mg/mL. Besides, the effective concentration of SFE producing TNF-${\alpha}$ is similar to IL-12, but it was the best activity at 1.25mg/mL. The level of MCP-1, IL-6 and IFN-${\gamma}$ depended on concentration from 0.16mg/mL to 10mg/mL, IFN-${\gamma}$ showed the best activity at the effective concentration of 0.63mg/mL. With the result of NK cell activity measurement, the spleen cell of mouse injected SFE had 1.5 times higher killing effect than non injected cell. Conclusions : The result of this studies is that Soybean fermetated extracts(SFE) has possibility to immune aided material for the function not only inhibition of microbial infection to macrophage but also activity of adaption immune and cellular immune system.
Journal of the Korea Institute of Information and Communication Engineering
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v.11
no.2
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pp.293-300
/
2007
As the development of the various IP-based services, it is expected that Internet telephony service will gradually replace the traditional PSTN-based telephony service. But there are many issues resolved to spread the Internet telephony service. One of them is to support the emergency services in the Internet telephony. In the case of USA, it has been regulated that 911 services should be supported in the Internet telephony services using VoIP on the similar performance level to PSTN 911 service. According to the regulation, basic VoIP 911 calls should be routed to the general access line of LEA without the location information or the callback number, but the enhanced VoIP 911 calls with the location information and callback number should be routed on the dedicated 911 network and destined to the local 911 distribution center such as PSAP. But, in the current VoIP-based Internet telephony network, the emergency call service has not been handled as one of the special services as well at has a worse performance in comparison to it on PSTN. Moreover, the service has a critical problem that it can not be destined to the nearest PSAP because of the insufficient information about the location information and the call back number. In this paper, we suggest the SIP-based emergency call service mechanism in order to resolve the problems above mentioned. This suggested mechanism is implemented to show its effectiveness and efficiency.
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