• Korean Journal of Clinical Pharmacy
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• v.26 no.2
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• pp.137-149
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• 2016

Objective: Online pharmacies were introduced in some countries such as United States of America or Canada. They can provide benefits to consumer because they can buy and take conveniently drugs without limitation of location or time. In Korea, online pharmacies are illegal and only pharmacists can sell drugs to consumers or patients. Therefore, we investigated the knowledge of online pharmacy and the possible problem in Korea to survey pharmacists. Methods: We developed questionnaire based on previous articles about online pharmacy and surveyed nation-wide pharmacists by mail or e-mail. The data was analyzed by SPSS and Microsoft Excel. P-values less than 0.05 were statistically significant. Results: 175 pharmacists involved in this study. About introduction of online pharmacies, 53.1% were opposition while 10.3% were approval and 36.6% were conditional. Although online pharmacies were introduced, 46.3% pharmacists do not have a plan to start online pharmacy. However, the approval and tends about starting online pharmacies were higher in younger pharmacists (20s, 30s) (p < 0.05). The criteria of permission about opening online pharmacies were 100% pharmacist license regardless of holding off-line pharmacy. 53.7% pharmacists responded education about taking medication is impossible. When online pharmacies are introduced, 65.1% pharmacists responded traditional pharmacies are affected negatively. Pharmacists concerned that the competition with large-sized distribution corporations, reduced reliance between pharmacists and patients, illegal transaction of counterfeit drugs, increased misuse of drugs. Conclusion: These results showed that Korea pharmacists have negative standard on online pharmacies. Therefore it is required to be more cautious before introducing online pharmacy and it need strict watching system and continuous education and study for safety after introducing online pharmacy.

• Journal of Ocean Engineering and Technology
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• v.27 no.4
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• pp.1-8
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• 2013

Many PE (pre-erection) blocks are supported by wooden, concrete, or steel supports when they are stocked in the outdoor areas of a shipyard. Their positions and numbers are planned on the basis of the workers' experience. Recently, many shipyards have been making PE blocks with various shapes and weight distributions because of the variety of ships and building technologies. Therefore, it is now necessary to deal with blocks that they have no experience with. We propose a method to conveniently and quickly evaluate the structural safety of PE block supports, without the need for special knowledge and technology related to structural analysis. This method can reduce the large number of man hours (MH) normally needed for the analysis. The three-dimensional grillage analysis is performed for a simplified grillage model of a PE block. For efficiency, the grillage model of the PE block is automatically built from its three-dimensional CAD model, and its weight is also automatically distributed on the grillage model. The integrated system has been comprehensively implemented to perform the grillage analysis for the reaction forces on block supports. This paper describes how to make a grillage model of a PE block and estimate the weight distribution of the block on this grillage model. These steps are verified by comparing the supports reaction forces to those of the 3D finite element analysis for the PE blocks that are provided by a shipyard.

• Journal of the Korean Institute of Landscape Architecture
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• v.32 no.5
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• pp.23-34
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• 2004

In this study, 1 dependent variable and 9 independent variables were established to examine suitable illuminance by spaces in urban parks in consideration of night users' psychological reactions and activity types. Such fixed variables were evaluated by a series of experiments of changing illuminance, and correlation among those variables was verified by correlation analysis and multiple regression analysis to suggest suitable illuminance by spaces. The results of this study are as follows: 1) The independent variables influencing suitable illuminance by spaces in urban parks were directly influenced rather by the psychological reaction of night users than the activity types by spatial functions. 2) Securing suitable illuminance by spaces commonly increased spatial availability, created certain atmosphere, and provided safety in the psychological reaction of night users. 3) Suitable illuminance by spaces in urban parks is: Central square is 31.88lx, resting space 6.30lx, exercising space 33.14lx, children's playground 14.19lx, pedestrian road 12.29lx, entry space 16.30lx, and green space 7.03lx. That is, when a place had more positive activities, spatial illuminance was increased. 4) Though comparison by spaces with the illuminance standard for urban parks as mentioned in KS A 3011-1993 can not be made, such illuminance was relatively compatible with the permissible range of illuminance in the author's opinion. It is expected that this study investigating suitable illuminance by spaces for night use in urban parks, will provide necessary knowledge for securing suitable illuminance by spaces in urban parks through classifyingin detail the illuminance standard of KS A 3011-1993. Besides, by helping make us aware of the importance of illuminance in urban parks as well as of external space in the night, this study will contribute to academic research and development in the field of landscape architecture and associated fields and be utilized in establishing legal and institutional standards.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.5
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• pp.2007-2011
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• 2014

Background: Human papilloma virus (HPV) is a common sexually transmitted infectious agent. It is estimated that 10% of all women worldwide are infected with HPV, that is some 660 million each year. HPV vaccination has a reported efficacy of more than 98% for protection against infection in females. In 2008 the Abu Dhabi Health Authority in the United Arab Emirates (UAE) introduced free HPV vaccination for all eligible schoolgirls in both public and private schools. Methods: A cross-sectional study of 640 women aged 18-50 years in the Emirate of Abu Dhabi in UAE from April 2012 to October 2012 was conducted. Results: Thirty-seven percent of the women in our sample had heard about HPV vaccination, and 80% of these would consider getting vaccinated themselves, and 87% would recommend vaccination to relatives or friends. Most women in the study (69%) had a favorable opinion about the vaccine. Only 17% of the women felt it might not be culturally acceptable, and 1% felt that there might be religious objections to HPV vaccination. Vaccine safety and recommendation by a doctor (36% each) were the factors identified most frequently by our sample of women which would enhance the uptake of the HPV vaccination. Conclusions: Knowledge about HPV vaccination among women in our sample was below average (37%); however, 80% of those who had heard about HPV vaccination were willing to be vaccinated themselves, and 87% would recommend vaccination to relatives and friends.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4871-4875
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• 2013

This meta-analysis was performed to evaluate and compare the outcomes of robotic gastrectomy (RG) and laparoscopic gastrectomy (LG) for treating gastric cancer. A systematic literature search was carried out using the PubMed database, Web of Knowledge, and the Cochrane Library database to obtain comparative studies assessing the safety and efficiency between RG and LG in May, 2013. Data of interest were analyzed by using of Review Manager version 5.2 software (Cochrane Collaboration). A fixed effects model or random effects model was applied according to heterogeneity. Seven papers reporting results that compared robotic gastrectomy with laparoscopic gastrectomy for gastric cancer were selected for this meta-analysis. Our metaanalysis included 2,235 patients with gastric cancer, of which 1,473 had undergone laparoscopic gastrectomy, and 762 had received robotic gastrectomy. Compared with laparoscopic gastrectomy, robotic gastrectomy was associated with longer operative time but less blood loss. There were no significant difference in terms of hospital stay, total postoperative complication rate, proximal margin, distal margin, numbers of harvested lymph nodes and mortality rate between robotic gastrectomy and laparoscopic gastrectomy. Our meta-analysis showed that robotic gastrectomy is a safe technique for treating gastric cancer that compares favorably with laparoscopic gastrectomy in short term outcomes. However, the long term outcomes between the two techniques need to be further examined.

• CELLMED
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• v.10 no.1
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• pp.7.1-7.6
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• 2020

Plants produce a wide range of active principles, making them a rich source of different types of medicines. Without any knowledge of the phytoconstituents or active principles the medicinal plants itself or in the form of polyherbal formulations, were used by all society of human being from ancient times for prevention and cure of disease, but most of the traditional formulations including the formulation of Ayurveda and Unani have not been scientifically validated in order to establish the pharmacopoeial standards to improve the efficacy. Globally, the people become conscious that uses of synthetic drugs for a long period is not safe; the trend of medical society at large is looking at alternatives from natural, safe sources to combat diseases. Due to this comprehension, it has been increased the demand for plant-derived medicine, and on the other side, it is extremely important to standardize the polyherbal formulations and validate them scientifically to improve their safety and efficacy. The polyherbal Unani formulation Safuf-e-Muallif is widely used and recommended in Unani system of medicine (USM) as a spermatogenic agent, semen thickening agent, etc. to treat sexual disorders viz. premature ejaculation, nocturnal emission, etc. The study mainly deals with phytochemical screening for the detection of nature of phytoconstituents and analytical technique like High-performance thin-layer chromatography (HPTLC) for developing fingerprint of Safuf-e-Muallif revealing specific identities of the drug. The phytochemical screening and HPTLC fingerprint profile for SM reported here may be used as a reference standard for quality control purpose in future.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.5
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• pp.589-601
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• 2014

Natural gas hydrate (NGH) is emerging as a new eco-friendly source of energy to replace fossil fuels in the 21st century. It is well known that the Natural Gas Hydrate contains large amount of natural gas about 170 times as much as its volume and it is easy to be stored and transported safely at about $-20^{\circ}C$ under atmospheric pressure due to so called "self-preservation effect". The option of gas transport by gas hydrate pellets carrier has been investigated and developed in various industry and academy. The natural gas hydrate pellet carrier is on major link in a potential gas hydrate process chain, starting with the extraction of natural gas from the reservoir, followed by the production of hydrate pellets and the transportation to an onshore terminal for further processing or marketing. In recent years, Korean project team supported by Korean Government has been working on the development of NGH total systems including novel NGH carrier since 2011. In order to increase the knowledge on the NGH pellet carrier developed and to understand the major hazards that could have significant impact on the safety of the vessel, this paper presents and evaluates the pros and cons of cargo holds, loading and unloading systems through the analysis of current patent technology. Based on the proven and well-known technologies as well as potential measures to mitigate sintering and minimize mechanical stress on the hydrate pellet in the self-preservation state, this study presents the conceptual and basic design for NGH carrier.

• The Journal of Pediatrics of Korean Medicine
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• v.32 no.2
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• pp.43-63
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• 2018

Objectives The purpose of this study is to evaluate the efficacy and safety of herbal medication for the treatment of nocturnal enuresis in children by analyzing randomized controlled trials conducted in China. Methods We searched literatures from China National Knowledge Infrastructure published up to 19 January, 2018. Selected literatures were collected and analyzed in order of publication year, and then demographic information, treatment method, duration of illness, duration of treatment, follow-up period, outcome measurement and adverse events. Results A total of 34 studies were selected for the analysis. In most studies, the total efficacy of the treatment group was reported to be higher than that of the control group, and the recurrence rate and complete cure rate were also found to be more effective in the herbal medicine treatment group. The most frequently used medical herb was Alpiniae Fructus (益智仁), and the use of medical herbs belong to tonifying yang (補陽藥), tonifying qi (補氣藥), and astringing essence strengthening collapse medicine (澁精縮尿止帶藥) were relatively high. The adverse events rate for the herbal medicine treatment group were significantly lower than those in the Western medicine treatment group. Conclusions This study showed that a herbal medicine treatment can be effective and safe option for treating pediatric nocturnal enuresis. However, additional well-designed clinical studies need to be performed to establish a basis.

• Korean Journal of Community Nutrition
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• v.21 no.6
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• pp.509-519
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• 2016

Objectives: Adulterated food education in adolescence period is very important because dietary management related to food safety is not made in a short period. This study aimed to identify dietary lifestyle factors which drive adulterated food management among middle and high school students. Methods: Data was collected from 270 middle and high school students in Daegu using a self-administered questionnaire in March and April of 2015. Data was analyzed using frequency analysis, one-way analysis of variance, ${\chi}^2$-test, factor analysis, reliability analysis, regression analysis, and cluster analysis. Results: The results of factor analysis indicated that adulterated food management awareness was classified into necessity, difficulty, and food purchasing anxiety. The adulterated food management capability was sub-grouped into environmental grasp, food identification, cooking hygiene, and situation management. The adulterated food management efficacy composed of management confidence, action intention, and knowledge. Dietary lifestyle comprised of gustation, family, and health factors after factor analysis, and it consisted of all seeking group, gustation seeking group, family seeking group, health seeking group, and family and health seeking group after cluster analysis. The gustation, family and health factors were significantly affected the factors of awareness, capability and efficacy of adulterated food management (p < 0.05). The frequency of health conditions, helping with meal preparation, and the times of eating out were significantly different according to seeking groups of dietary lifestyle (p < 0.01). The scores of awareness, capability and efficacy of adulterated food management of family and health seeking group were significantly higher than the other seeking groups (p < 0.05). Conclusions: This study suggests that adulterated food management education programs should account for gustation, family and health factors of dietary lifestyle to be effective for adolescents.

• Journal of Environmental Impact Assessment
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• v.20 no.5
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• pp.705-716
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• 2011

For the efficient discovery of knowledge and information from the observed systems, data mining techniques can be an useful tool for the prediction of water quality at intake station in rivers. Deterioration of water quality can be caused at intake station in dry season due to insufficient flow. This demands additional outflow from dam since some extent of deterioration can be attenuated by dam reservoir operation to control outflow considering predicted water quality. A seasonal occurrence of high ammonia nitrogen ($NH_3$-N) concentrations has hampered chemical treatment processes of a water plant in Geum river. Monthly flow allocation from upstream dam is important for downstream $NH_3$-N control. In this study, prediction models of water quality based on multiple regression (MR), artificial neural network and data mining methods were developed to understand water quality variation and to support dam operations through providing predicted $NH_3$-N concentrations at intake station. The models were calibrated with eight years of monthly data and verified with another two years of independent data. In those models, the $NH_3$-N concentration for next time step is dependent on dam outflow, river water quality such as alkalinity, temperature, and $NH_3$-N of previous time step. The model performances are compared and evaluated by error analysis and statistical characteristics like correlation and determination coefficients between the observed and the predicted water quality. It is expected that these data mining techniques can present more efficient data-driven tools in modelling stage and it is found that those models can be applied well to predict water quality in stream river systems.