• Title/Summary/Keyword: Safety Health

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Oxidative DNA Damages and Its Repair Enzyme Acitivities in the SD rats by Repeated Inhalation Exposure to the Hexavalent Chromium

  • Seung-Hee Maeng;Il-Je Yu;Hyun-Young Kim;Cheol-Hong Lim;Jong-Yoon Lee;Kwon-seob Lee;Yong-Mook Lee;Ho-Keun Chung;Hai-Won Chung
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.151-151
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    • 2001
  • According to the epidemiological studies in chromium workers, hexavalent chromium is associated with the risk of lung cancer. Reactive oxygen species produced by hexavalent chromium exposure may play an important role in the carcinogenesis process. We measured one kind of oxidative DNA damages, 8-hydroxydeoxyguanosine (8-OHdG) and its repair activities as an indicators of cellular oxidative stress in rat lungs by the repeated inhalation exposure to sodium chromate.(omitted)

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MICRONUCLEI INDUCTION BY REPEATED INHALATION EXPOSURE TO THE 1,1-DICHLORO-1-FLUOROETHANE BUT NOT BY THE SINGLE PERITONEAL INJECTION

  • Maeng, Seung-Hee;Chung, Hai-Won;Kim, Hyun-Young;Lim, Cheol-Hong;Lee, Jong-Yoon;Chung, Yong-Hyun;Lee, Yong-Mook;Chung, Ho-Keun;Yu, Il-Je
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.179-179
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    • 2001
  • To investigate the genotoxic effect of 1, 1-dichloro-1-fluoroethane which was widely used as a cleaning solvent at the electronic part industry, the micronucleus frequencies were recorded by examining polychromatic erythrocytes in bone marrows of single i.p. injected mice at high doses and of the repeatedly inhaled rats for 13 weeks at relatively low concentrations.(omitted)

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Effect of Occupational Safety and Health-related Communication in Manufacturing Industry on Safety and Health Management Level - The Number of Supervisors as Mediating Factor - (제조업의 산업안전보건 관련 의사소통이 안전보건경영 수준에 미치는 영향 - 관리감독자 인원의 매개효과를 중심으로 -)

  • Kim, You-ri;Lee, Si-young;Chen, Mee-hye;Park, Ji-young;Lim, Mi sun;Lee, Jin-a;Jung, Hye-sun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.31 no.4
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    • pp.494-502
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    • 2021
  • Objectives: The purpose of this study is to identify the general characteristics of manufacturing workplaces and the characteristics of safety and health organizations, and to determine the impact of safety and health-related communication within these organizations mediated by supervisory safety and health management personnel. Methods: This study is based on the Korea Occupational Safety and Health Agency's 2018 Occupational Safety and Health data targeting 1,486 manufacturing sites. Data were analyzed using descriptive statistics, t-test and ANOVA, and mediator variable regression analysis using SPSS 25.0. Results: The average score on communication levels related to safety and health was 11.20 out of 15. The average score of the safety and health management level was 31.04 out of 40. As a result of mediation regression analysis, it was found that safety and health-related communication had an effect on the safety and health management level (𝛽=0.434), and the number of safety and health supervisors was found to mediate the effect of this variable (𝛽=0.069). Conclusions: The level of safety and health-related communication affects the level of health and safety management, and the number of supervisors mediates this influence. Therefore, the role of the supervisor is important in safety and health communication. It is expected that the level of safety and health management can be improved through management and supervisors.

A Study on the Better Operation of Occupational Safety and Health Management Systems

  • Choi, Jae-Wook;Yoon, Seok-J.;Lee, Gwan-Hyung;Yang, H.S.
    • International Journal of Safety
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    • v.4 no.1
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    • pp.32-37
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    • 2005
  • This study was conducted to identity the characteristics of occupational health and safety management systems around the world, to survey the implementation of OHSMS in Korean companies, to find problems and corrective measures, and to understand the opinions of top management about OHSMS. Questionnaires on the operation of occupational health and safety management systems in Korean manufacturing companies were carried out. Occupational health and safety management systems around the world, including OHSAS 18001, BS8800, KOSHA 18001, VPP, J-OHSMS, were reviewed. In order to implement an occupational health and safety management system successfully, it was found that the management should consider occupational health and safety as important, provide employees with necessary training, and have a strong commitment to occupational health and safety.

Oxidative DNA Damage from Nanoparticle Exposure and Its Application to Workers' Health: A Literature Review

  • Rim, Kyung-Taek;Song, Se-Wook;Kim, Hyeon-Yeong
    • Safety and Health at Work
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    • v.4 no.4
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    • pp.177-186
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    • 2013
  • The use of nanoparticles (NPs) in industry is increasing, bringing with it a number of adverse health effects on workers. Like other chemical carcinogens, NPs can cause cancer via oxidative DNA damage. Of all the molecules vulnerable to oxidative modification by NPs, DNA has received the greatest attention, and biomarkers of exposure and effect are nearing validation. This review concentrates on studies published between 2000 and 2012 that attempted to detect oxidative DNA damage in humans, laboratory animals, and cell lines. It is important to review these studies to improve the current understanding of the oxidative DNA damage caused by NP exposure in the workplace. In addition to examining studies on oxidative damage, this review briefly describes NPs, giving some examples of their adverse effects, and reviews occupational exposure assessments and approaches to minimizing exposure (e.g., personal protective equipment and engineering controls such as fume hoods). Current recommendations to minimize exposure are largely based on common sense, analogy to ultrafine material toxicity, and general health and safety recommendations.

Development and Use of Data for Chemical Risk Assessment (화학물질 유해성 평가를 위한 정보의 작성 및 활용)

  • Rim, Kyung-Taek;Kim, Hyun-Ok;Kim, Young-Kyo;Cho, Hae-Won;Ma, Yong-Seok;Lee, Kwon-Seob;Lim, Cheol-Hong;Kim, Hyeon-Yeong;Yang, Jeong-Seon
    • Environmental Analysis Health and Toxicology
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    • v.22 no.1 s.56
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    • pp.91-101
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    • 2007
  • The new chemicals are developed and circulated without the verified toxicity data. So, the accidents and occupational diseases, such as explosion, fire, suffocation about deadly poisons etc. are frequently to workers. Classifications of chemicals suited with guideline and an offer of correct chemical information data are the molt important thing for the establishment of suitable chemical management system. The GHS (Globally Harmonized System of classification and labeling of chemicals) is based with the chemical classifications and unification plan. The warning symbol and phrases are established for improvements of chemical information data system. According to these unified and improved systematic form of data, and the chemical information data, the workplaces will be presented many chemical safety and risk data correctly. In this paper, we will present constructions and accomplishment contents-based chemical management of workplace through development of chemical information data and the nice using for new chemical investigation and risk assessment of chemicals in workplaces.

Evaluation of the Quality of Occupational Health and Safety Management Systems Based on Key Performance Indicators in Certified Organizations

  • Mohammadfam, Iraj;Kamalinia, Mojtaba;Momeni, Mansour;Golmohammadi, Rostam;Hamidi, Yadollah;Soltanian, Alireza
    • Safety and Health at Work
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    • v.8 no.2
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    • pp.156-161
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    • 2017
  • Background: Occupational Health and Safety Management Systems are becoming more widespread in organizations. Consequently, their effectiveness has become a core topic for researchers. This paper evaluates the performance of the Occupational Health and Safety Assessment Series 18001 specification in certified companies in Iran. Methods: The evaluation is based on a comparison of specific criteria and indictors related to occupational health and safety management practices in three certified and three noncertified companies. Results: Findings indicate that the performance of certified companies with respect to occupational health and safety management practices is significantly better than that of noncertified companies. Conclusion: Occupational Health and Safety Assessment Series 18001-certified companies have a better level of occupational health and safety; this supports the argument that Occupational Health and Safety Management Systems play an important strategic role in health and safety in the workplace.

A Study on the Necessity and Action Plan of Establishment of Occupational Safety and Health Executive in Korea (산업안전보건청의 설립 필요성과 추진방안에 관한 연구)

  • Jung, Jinwoo
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.27 no.1
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    • pp.1-12
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    • 2017
  • Objectives: The major objectives of this study are to review the requirements for the advancement of occupational safety and health administrative organization and to propose measures to establish an Occupational Safety and Health Executive. Methods: The problems of occupational safety and health administrative organization in korea were examined empirically and cases of occupational safety and health administrative organizations in developed countries were investigated (United Kingdom, United States, Germany, and Japan). A plan for establishing an Occupational Safety and Health Executive was proposed over the short and medium term. Results: An occupational safety and health administration is characterized by a professional and technical nature, and even more so in modern society. Therefore the greatest value required by an occupational safety and health administrative organization is expertise. In addition, administrative values it requires include efficiency, specificity, independence, and activity. The Korean occupational safety and health administrative organization has a number of problems in terms of these values. The most appropriate way to realize these values is to establish an Occupational Safety and Health Executive. It is desirable to establish such an Occupational Safety and Health Executive in a phased manner taking into consideration its relationship with Korea Occupational Safety and Health Agency(KOSHA), including KOSHA's functional adjustment Conclusions: In order to solve the deep-seated problems in occupational safety and health administrative organization and to advance occupational safety and health administration in Korea, it is necessary to establish an Occupational Safety and Health Executive as a foundation for achieving an advanced industrial safety and health administration.

1,1-Dichloro-1-fluoroethane Induces Micronuclei in Bone Marrow Cells by Repeated Inhalation Exposure but not by the Single Peritoneal Injection

  • Maeng, Seung-Hee;Kim, Hyun-Young;Lim, Cheol-Hong;Lee, Jong-Yoon;Lee, Yong-Mook;Chung, Ho-Keun;Chung, Hai-Won;Yu, Il-Je
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.150-150
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    • 2001
  • To investigate the genotoxic effect of 1, 1-dichloro-1-fluoroethane, which was widely used as a cleaning solvent at the electronic part industry, the micronucleus frequencies were recorded by examining polychromatic erythrocytes in bone marrows of the rodents exposed to it with different routes.(omitted)

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