• Journal of Society of Preventive Korean Medicine
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• v.20 no.1
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• pp.125-144
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• 2016

Objectives : About 13% of the medicines used by traditional korean medicines(TKM), are called animal medicines and are derived from non-herbal sources such as animals and insects. However, the clinical use of these preparations from animal medicines is often based on tradition and belief, rather than on evidence of toxicity and efficacy. As a result, animal medicines containing toxin have caused serious problems from injecting patients with venom. Here, various venoms frequently used as TKM were reviewed in terms of their instinct toxity and tried to estimate their safety classification. Methods : The estimation of safety classification was based on human equivalent dose(HED)-based MOS (margin of safety) and clinical dose applied for patients. Results and Conclusions : Except that of snake venom due to no clinical dose, they were evaluated as class 3 for bee venom, class 4 for cantharidin, toxin from blister beetle, and class 1 for venom from scolopendrid. In conclusion, animal medicines showed a wide range of safety classification from class 1 to class 4. This wide range is estimated to result from extremely limited applications of each venom for patients because of their strong toxicity. However, it should be cautious for application in clinics since animal medicines can produce anaphylactic reactions particularly after veinous administration even with a tiny amount of venom.

• Journal of the Korean Society of Safety
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• v.27 no.4
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• pp.83-89
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• 2012

In order for start-up establishment to enter the business market, it has to get over the first mover advantage of the existing establishment. As a result, its working condition deteriorates and a great deal of occupational accidents take place. Based on 2009 standard, the occupational accident rate of start-up establishment is 1.28%, which is two times higher than existing establishment and the gap between manufacturing and service industry has been getting wide. For the characteristic of injured person in start-up establishment, it is showed that the occupancy rate of women and people with less than 30 age starting out in a career is high and the occupancy rate of occupational accident for holiday and night work is high. Therefore, the act for occupational accident prevention is needed in the early period of business and underprivileged group for occupational accident.

• Proceedings of the KSR Conference
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• 2009.05a
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• pp.855-859
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• 2009

In this paper, we introduce the estimation method by Risk or SIL(Safety Integrity Level) for the criterion of safety assurance and summarize each application method and target. IEC 62278(EN 50126) which is international standard for the specification and verification of the railway system RAMS indicate a criterion of safety assurance. Especially, it recommend the safety verification by continuous verification as the order of requirement establishment, design, manufacture, installation, operation, and maintenance for the equipment not easy to quantify the operation environment. In this paper, we study the SIL requirement allocation method relating to internal new system development and existing system improvement by analysing SIL recommendations which were used to understand SIL for a train control equipment in 1990s in IRSE and theoretically their allocation background. This paper help the safety management of Korea train control system to develope the quantitative management procedure as international level by analyzing the SIL requirement allocation by operation agency and the right SIL verification procedure by manufacture and indicating the example to assure safety because it is necessary for improvement and localization for the Korea train control system having highly dependence on aboard technology.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2001.10a
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• pp.425-431
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• 2001

In order to take account of the statistical properties of probability variables used in the structural analysis, the conventional approach using the safety factor based on past experience usually estimated the safety of a structure. The real structures could only be analyzed with the error in estimation of loads, material characters and the dimensions of the members. But the errors should be considered systematically in the structural analysis. Structural safety could not precisely be appraised by the traditional structural design concept. Recently, new approach based on the probability concept has been applied to the assessment of structural safety using the reliability concept. In this study, safety of structures will estimated by the reliability analysis with commercial structural software that has the tools of nonlinear elastic-plastic 3-D analysis. Experimental test result is compared to results from this research and Coan/sup 1)/ In this paper, AFOSM(Advanced First-Order Second Moment method) is applied with von Mises, Tresca and Mohr-Coulomb failure criterions. The reliability index β and probability of failure P/sub f/ can be obtained by following this practical procedure as judgement a safety of structures and necessity of reinforcing.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.21 no.7
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• pp.637-642
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• 2011

The DMT freight is judged that economic performance is good because can increase cargoes than existing freight. However, the existing freight cars, each with a different balance to the body structure is bogie because the vibrations may occur. Thus, by minimizing vibration over the existing freight securing the safety of the driving if you will not have major problems in cargoes. In this study, multi-body dynamic analysis tool, VI-Rail using the actually Gyeongbu Railroad line and an empty, full freight condition include curve radius, track irregularity, The DMT freight of the derailed wagons were assessed for safety analysis. Full and empty freight conditions for parity in the Gyeongbu Railroad line(Dongdaegoo${\leftrightarrow}$Kyungsan) derailment safety analysis, such as derailment coefficient and the wheel unloaded, echoing the curve and the orbit is affected by the irregularity was found. Full freight condition than the empty conditions showed a significant derailment safety. Overall, the limits of derailment coefficient(Q/P = 0.8) and wheel unload decrement limits(${\triangle}P/P$ = 0.6) is less safe with me confirmed that the derailment safety.

• Journal of the Korean Society of Safety
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• v.36 no.3
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• pp.7-14
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• 2021

Hybrid laminated Al/carbon-fiber-reinforced plastic (CFRP) composites are attracting considerable attention from industries such as aerospace and automobiles owing to their excellent specific strength and specific rigidity. However, when this material is used to fabricate high-pressure fuel storage containers subjected to repeated fatigue loads, fatigue life evaluation for the working load is regulated as an important criterion for operational safety and ease of maintenance. Among the existing evaluation methods for these vessels, the burst test and the hydraulic repeat test require expensive facilities. Thus, the present study aims to develop an improved fatigue life test for Al/CFRP laminated hybrid composites. The test specimen was manufactured using a curved mold considering the shape of a type III high-pressure storage container. The strain-life method was used for fatigue life evaluation, and the life was predicted based on the transition life. The results indicate that the more complex the CFRP stacking sequence, the longer is the transition life. This test method is expected to be useful for ensuring the fatigue safety and economy of hybrid laminate composites.

• Journal of the Korean Association of Geographic Information Studies
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• v.19 no.1
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• pp.167-179
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• 2016

The safety of SOC facilities is constantly under threat by the globally increasing abnormal climate. Responding to disasters requires prompt decision-making such as suggesting evacuation paths. For doing so, spatio-temporal information with convergence of disaster information and SOC facility information must be utilized. Such information is being collected separately by the government or related organizations, but not collectively. The collective control of the separately collected disaster information and the generation of SOC facility safety and damage information are required for prompt disaster response. Also, as disaster information requires spatio-temporal convergence in its nature, the construction of an inventory that integrates related information and assists disaster response decision-making is required. A plan to construct a facility importance, risk, and damage estimation inventory for assisting prompt disaster response decision-making is suggested in this study. Through this study, the disaster and SOC facility-related data, which are being managed separately, can be collected and standardized. The integrated information required for the estimation of facility importance, risk, and damage can be provided. The suggested system is expected to be used as a decision-making tool for proactive disaster response.

• Nuclear Engineering and Technology
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• v.53 no.8
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• pp.2534-2546
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• 2021

Nuclear emergency preparedness and response is an essential part to ensure the safety of nuclear power plant (NPP). Key support technologies of nuclear emergency decision-making usually consist of accident diagnosis, source term estimation, accident consequence assessment, and protective action recommendation. Source term estimation is almost the most difficult part among them. For example, bad communication, incomplete information, as well as complicated accident scenario make it hard to determine the reactor status and estimate the source term timely in the Fukushima accident. Subsequently, it leads to the hard decision on how to take appropriate emergency response actions. Hence, this paper aims to develop a method for rapid source term estimation to support nuclear emergency decision making in pressurized water reactor NPP. The method aims to make our knowledge on NPP provide better support nuclear emergency. Firstly, this paper studies how to build a Bayesian network model for the NPP based on professional knowledge and engineering knowledge. This paper presents a method transforming the PRA model (event trees and fault trees) into a corresponding Bayesian network model. To solve the problem that some physical phenomena which are modeled as pivotal events in level 2 PRA, cannot find sensors associated directly with their occurrence, a weighted assignment approach based on expert assessment is proposed in this paper. Secondly, the monitoring data of NPP are provided to the Bayesian network model, the real-time status of pivotal events and initiating events can be determined based on the junction tree algorithm. Thirdly, since PRA knowledge can link the accident sequences to the possible release categories, the proposed method is capable to find the most likely release category for the candidate accidents scenarios, namely the source term. The probabilities of possible accident sequences and the source term are calculated. Finally, the prototype software is checked against several sets of accident scenario data which are generated by the simulator of AP1000-NPP, including large loss of coolant accident, loss of main feedwater, main steam line break, and steam generator tube rupture. The results show that the proposed method for rapid source term estimation under nuclear emergency decision making is promising.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.6
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• pp.890-898
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• 2022

Dispersion of suspended sediment, caused by coastal and marine development, is a key item in assessing marine environmental impact as it adversely affects marine life by increasing the level of turbidity and decreasing the amount of sunlight in seawater. However, its estimation has not been reliable because of the absence of a standard for the data measurement and divergent approaches to the impact assessment. In this study, we examined the estimation models from 58 Marine Environmental Impact Statements (MEISs, 2012-2014) to identify the gaps in the assessment and devise ways of improving the estimation. We developed four index items-grid system; unit load, particle size, and settling velocit-to evaluate their reliability in the estimation. The mean reliability score of each index was overall low-25 for grid system, 60 for unit load, 34 for particle size, and 17 for settling velocity. To ensure high reliability, it is important to develop a standard guideline that defines precise measurement of suspended sediment for unit load and settling velocity by particle size, followed by a grid system with compatible size for modelling. This can improve the estimation and thus underlie coherent impact assessment of suspended sediment dispersion on marine environment.

• Journal of the Korean Society of Marine Environment & Safety
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• v.23 no.3
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• pp.258-265
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• 2017

This paper validates a system identification method using mathematical optimization using sea trial measurement data as a benchmark. A fast time simulation tool, SIMOPT, and a Rheinmetall Defence mathematical model have been adopted to conduct initial hydrodynamic coefficient estimation and simulate ship modelling. Calibration for the environmental effect of sea trial measurement and sensitivity analysis have been carried out to enable a simple and efficient optimization process. The optimization process consists of three steps, and each step controls different coefficients according to the corresponding manoeuvre. Optimization result of Step 1, an optimization for coefficient on x-axis, was similar compared to values applying an empirical regression formulae by Clarke and Norrbin, which is used for SIMOPT. Results of Steps 2 and 3, which are for linear coefficients and nonlinear coefficients, respectively, was differ from the calculation results of the method by Clarke and Norrbin. A comparison for ship trajectory of simulation results from the benchmark and optimization results indicated that the suggested stepwise optimization method enables a coefficient tuning in a mathematical way.