• Title/Summary/Keyword: Safety & Health department

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Studies on the Cultural and Serological Tests of Mycoplasma Pulmonis in Laboratory Animal. (실험동물에 Mycoplasma Pulmonis의 배양 및 혈청학적 시험)

  • Kim Jae Yeon;Lee Yong Hee
    • Journal of environmental and Sanitary engineering
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    • v.1 no.1 s.1
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    • pp.69-79
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    • 1986
  • This studies were carried out to investigate the high infection sites from various specimens, cultural isolation on the susceptible media and specific antibody titres of M. pulmonis in experimental 310 mice and 330 rats obtained from two breeding facilities. Efficiency of complement faxation test (CF test) for detection of M. pulmonis antibody in mice and rats were compared directly with the diagnostic cultural isolation method. 1. Isolation rates of M. pulmonis among infection sites were about 30% from the oral cavities and $40\%$ from the middle ear of mice. The rates were $100\%$from the nasal cavaties and $90\%$ from the oral cavities of rats. 2. The infection rates were $12\%$ to A group and $16\%$ to B group of mice. The rates in the rats were $55\%$ to A group and $70\%$ to B group. 3. The M. pulmonis antibody titres by CF test were $73\%$ of total 100 mice in serum dilution below 1:5 (< 1:5), and $24\%$ of total samples in antibody titres above 1:5 (> 1:5), but 3 samples were not showed anticomplementary activities. The antibody titres in rats were $35\%$ of 120 rats in below 1:5 (< 1:5), and $61\%$ of total samples in above 1:5 (> 1:5), but the remained were not showed anticomplementary activities.

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A study on curing the wounded heart applications development and effect analysis by utilizing narrative therapy techniques (이야기치료 기법을 활용한 마음상처 치유 어플리케이션 개발 및 효과분석)

  • Ha, Tai-Hyun;Baek, Hyeon-gi
    • Journal of Digital Contents Society
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    • v.16 no.2
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    • pp.207-218
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    • 2015
  • This study is to design and implement Smartphone application by applying the principles and processes of narrative therapy for the participants. The application is able for participants to fight out of the difficulty in question centered on the issue, and to be able to find a positive new stories to be evolving the story of their lives as well. Therefore, using the application will help them to live a healthier life out of the problems. As a way of currying the wounded heart of the youth, narrative therapy techniques were applied to Smartphone appliances accustomed to the youth. The youths' wounded minds will not only be easily cured but also can be a important factor in determining the direction of life. In this study, narrative flow was structured into four stages; relationships, externalization, creating new stories and strengthening the new story bsed on Doll & Doll' theory. Based on them, the Smartphone application for curing the wounded heart was designed and developed by utilizing narrative therapy techniques. The application was tested by 30 University students in Jeonbuk province in Korea and the results showed that they were satisfied with the application with relation to improving their heart health.

A Study on the Quality Control of $^{18}F$-FDG Radiopharmaceutical ( $^{18}F$-FDG 방사성의약품의 품질관리에 관한 조사)

  • Kim, Ssang-Tae;Yong, Chul-Soon;Han, Eun-Ok
    • Journal of Radiation Protection and Research
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    • v.35 no.4
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    • pp.151-156
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    • 2010
  • The types of test items which were recorded in this test report of quality control domestic $^{18}F$-FDG radiopharmaceutical which consisted of 13 different types: appearance, half-life, radioactive heterokaryosis, radiochemical Confirmation (measure of Rf value), radiochemical Purity, Ethanol, Acetonitrile, Kryptofix, Aluminium, pH, Endotoxin, aseptic test, and radioactivity${\cdot}$ml-1. The record was fully recorded in 'appearance', 'radioactive heterokaryosis', 'pH', 'Endotoxin', and 'aseptic test'. In 'half-life', 'radiochemical Confirmation (measure of Rf value), 'radiochemical Purity', 'Ethanol', 'Acetonitrile', 'Kryptofix', 'Aluminium', 'radioactivity${\cdot}$ml-1', there were differences in records of each manufacturing business on radioactive medicine and medical supplies. The result of the test showed all 13 items of quality control test were 100% suitable on the basis of recorded data. There were more radiopharmaceutical made in the laboratory than in hospitals and businesses and in for result of suitability test, the laboratory showed higher suitability than did the hospitals or businesses. Domestically, there are differences of the test report items in the safety of radiopharmaceutical of each facility, and since it is not standardized, supplements are needed. To submit standardized test reports of quality guarantee in radiopharmaceutical, GMP of U.S. and CE Mark of Europe should be referred as well as receiving advice from professionals to standardize as suitable domestic standard.

Comprehensive Analysis of Exposed Adverse Factors in Disaster Response Activities - Focused on Fire - (재난 대응 활동 시 노출가능 유해인자 종합분석 -화재 현장을 중심으로-)

  • Park, Chanseok
    • Journal of the Society of Disaster Information
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    • v.10 no.3
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    • pp.420-430
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    • 2014
  • Firefighters performing disaster response activities such as Fire Suppression Rescue First Aid in fire are being exposed in various adverse factors, heat, smoke, toxic gases, emotional stress, biological toxic factors and physical overload by unnatural ergonomic posture required for firefighters. But so far, there is the study for this problem only separately. There is no study about comprehesive analysis of exposed adverse factors in fire-related disaster response activities and countermeasures. The purpose of this study is to contiribute to solving the health problems and prevention of accidents of firefighters by extracting hazardous agents in disaster such as fire and by proposing countermeasures. After analyzing circumstances such as fire-suppression, rescue first aid and life-environment, exposure factors of fire are derived and exposure status is suggested according to physical chemical biological psychological aspects. The countermeasure against the noise of the physical exposure factors are proposed. The countermeasures such as protective equipment and clean room in chemical factors, infection prevention education, vaccination and periodic check system in biological factors, PTSD alleviation booth and mentoring in psychological factors are proposed.

Comparative Drug Evaluation of Atorvastatin versus Rosuvastatin in Pharmacotherapy of Korean Patients with Dyslipidemia

  • Park, Seon-Young;Lee, Myung-Koo;Lim, Sung-Cil
    • Biomolecules & Therapeutics
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    • v.16 no.1
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    • pp.54-60
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    • 2008
  • Dyslipidemia is the multiple lipid metabolic disorders which is one of the high risk factors for the atherosclerotic diseases. It increases the morbidity and mortality and therefore, must be treated with antilipidemic agents. HMG-Co A reductase inhibitors (statins), one of many antidyslipidemic agents, have shown to be significant improvement from the various cholesterol levels. Especially, data from many comparative trials suggest that rosuvastatin is more effective than atorvastatin among many other statins. The aims of this study were to evaluate the efficacy and safety between rosuvastatin and atorvastatin in the treatment of Korean patients with dyslipidemia. Currently the Korean Society of Lipidology and Atherosclerosis based on the Korean health screening data suggests that Korean patients with dyslipidemia should be treated by the target cholesterol levels according to the Adult Treatment Panel III guidelines of the US National Cholesterol Education Program (NCEP-ATP III). We reviewed retrospectively all medical histories of the total 392 dyslipidemic patients with atorvastatin or rosuvastatin from June 1st, 2004 to August 31st, 2006 in Chungbuk National University Medical Center. Patients were classified as total 4 groups by the NCEP-ATP III Guidelines. The numbers of enrolled patients were each 5 mg atorvastatin (n=34), 10 mg atorvastatin (n=148), 5 mg rosuvastatin (n=94) and 10 mg rosuvastatin (n=82). In comparison between groups, rosuvastatin groups in the lowering LDL-C had better efficacies, and the results were each 22% (5 mg atorvastatin), 33.3% (10 mg atorvastatin), 35% (5 mg rosuvastatin) and 41.3% (10 mg rosuvastatin) with the dose relationship (P=0.000). Rosuvastatin groups also have shown to be more significantly reducing Total Cholesterol levels compared to atorvastatin groups with the no dose relationship (P=0.000). In the lowering of non-HDL cholesteroles, rosuvastatin groups showed significantly better efficacies than atorvastatin with the dose-relationship (P=0.000). Each medication groups did not demonstrate the differences in the changing of HDL cholesterol and triglyceride levels (P=0.096, 0.309, respectively). In conclusion, rosuvastatin was better efficacious than atrovastatin in reducing LDL-C Total Chol, and Tg. Therefore, rosuvastatin is a good antilipidemic agents for Korean patients with dyslipidemia and it can use to minimize the morbidity and mortality related to the cardiovascular diseases in Korean.

A Study for the Appropriateness of the Different Reference Points in the Analysis of Working Posture

  • Kim, Day-Sung;Kim, Chol-Hong
    • Journal of the Ergonomics Society of Korea
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    • v.30 no.5
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    • pp.637-644
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    • 2011
  • Objective & Background: When applying various evaluation tools that analyze work posture risk through observation, accurate measurement of body flexion angle is very important. Method: This study investigated differences and appropriateness of 5 different existing reference points commonly used in the analysis of the work posture. Twenty five ergonomist and trained professionals were participated in this study. A Same flexion angle was utilized for the evaluation of risk assessment of musculoskeletal disorders using five different reference points to investigate the degree of difference between them. To investigate how different the observers' preferred flexion angle measuring methods were compared to the ISO 11226 Reference Posture, a virtual body model was constructed using the Poser 6.0 program. Six types of body flexion postures were constructed, and since neck flexion differs according to body angle, five types of neck flexion postures were constructed with the trunk bending $20^{\circ}$ forward, making up a total of 30 virtual flexion postures. Results: Results showed that the observers used personally preferred reference points instead of reference points recommend in the evaluation tools. Also the results revealed the their seems to be 6 types of flexion angle for the trunk and 11 types of measurement methods for the neck flexion angle in the form of personally preferred reference points. The results showed that a mean difference of $14^{\circ}$($4{\sim}23^{\circ}$) occurred in the trunk, and a mean difference of $20^{\circ}$($-8{\sim}51^{\circ}$) occurred in the neck. To increase accuracy when using the 5 evaluation tools in combination, the ISO 11226 standards, observers' preferred flexion posture standards, and common flexion posture standards of the evaluation tools were compared with the reference points of the 5 evaluation tools. Results showed considerable variance in angle difference for each evaluation tool. Conclusion: According to the results of this study, considering the angle difference between the flexion angle reference points of the evaluation tool and the reference points selected by the observers, it is concluded that instead of personally preferred reference points, the standardized reference points to enhance the accuracy and the objectivity. Application: The result of this study can be used as reference guide to develop the standardized reference point in the future.

A Basic Study for Single Shell Support System of Railway Tunnel (철도 터널의 싱글쉘 지보시스템 적용에 관한 기초 연구)

  • Jung, Daeho;Jeong, Cahnmook
    • Journal of the Korean GEO-environmental Society
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    • v.17 no.1
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    • pp.39-48
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    • 2016
  • In this study, it can be shortened tunnel construction work period by introducing a single-shell tunnel does not placing the secondary concrete lining, a global research trend, reduction of the cost of the lining placement and number of benefits that can ensure the safety of long-term tunnel with a single shell it was to study the tunnel method. First, we analyze the design and construction practices relating to delete lining of the domestic design and construction practices and a comprehensive analysis of the stability study found a rock in good condition interval (1~3 grades), we propose that the lining uninstalled. In the case of domestic changes on the ground floor is very heavy underfoot conditions many so tunneling method by single shell as ground conditions are good and one preferred the water points that apply in less soil, the soil health and poor sections (4~5 grades) reflecting with respect to the concrete lining that is expected reasonable.

An inquiry into dental personnel's Knowledge, attitude and behavior about the defense against dental radiation (치과 의료기관 종사자의 방사선 방어에 대한 지식, 태도 및 행위)

  • Kim, Sun-Ju
    • Journal of Korean society of Dental Hygiene
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    • v.4 no.1
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    • pp.15-29
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    • 2004
  • The purpose of this study was to understand the relationship among knowledge, attitude, and behavior of dental personnel about the defense against dental radiation according to general features, and help them recognize the importance of defense against dental radiation. A questionnaire survey of 187 dental personnel who were working in 121 medical institutions such as university hospitals, general hospitals, hospitals, clinics, and public health centers in Seoul area was conducted from December 2002 to January 2003. Study findings are as follows: 1. The average knowledge score for the defense of radiation was 9.51(full score=14): By the demographic features, the know level for the defense of radiation was appeared to be different with the occupational category, age, academic background, workplace, year of working, and whether having the education of radiation or not. By questionnaire items, the knowledge for the defense of radiation was high in general, but for the item. 'the average amount of being bombed with radiation according occupations cannot be over 20mSv in a year for prescribed 5 years'. it was 18.7%: and for the item. 'the longer the length between focus and film. the less the amount of skin exposure', it was 40.6%. showing less knowledge for these two items. 2. The average attitude score for the defense of radiation was 64.24 (full score=75): By the demographic features, the attitude score was higher with respondents who were 31-35 years old. 11-15 years of working. and having radiation education. The attitude score by questionnaire items was generally high for all the items. 3. The average behavior score for the defense of radiation was 45.43: (a) By the demographic features, the behavior score for the defense of radiation was appeared to be higher with respondents who were dentists for occupational category, the aged for age, holding higher diploma for academic background, working in the university hospitals for workplace, and having longer occupational career for the year of working. (b) The behavior score for the defense of radiation by questionnaire items was lower than that of the attitude score for all the items. For the item, 'the amount of X-ray radiation is adjusted according to such conditions as patients' age, radiating areas, and kind of films', the score was 4.03; and for the item, 'Must receive the education of safety management of radiation periodically', the score was 1.73 and it was the lowest one. 4. As for the correlation among the knowledge, attitude, and behavior for the defense of radiation, the higher the level of knowledge and attitude, the higher the level of behavior.

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A Quantitative Risk Analysis of LPG Leaked During Cylinder Delivery (가스용기 운반 중 누출된 LPG의 정량적 위험 분석)

  • Kim B-J,;Park Ki-Chang;Lee Kuen-Won
    • Journal of the Korean Institute of Gas
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    • v.7 no.2 s.19
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    • pp.33-41
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    • 2003
  • There exists high hazard when transporting LPG as well as using, storing, and producing. For small scale LPG consumer, retailers deliver LPG to customers via a truck loading many LPG cylinders. Suppose there occurred a accident during LPG cylinder transfer, this could result in serious damages to the life and properties in the near or neighbor of the accident spot. In this regard, we made a quantitative risk analysis to estimate the possible damages and the probability through the identification of accidents causes and the simulation of the possible scenario. In this study, we made the Excel & Visual Basic computer program to perform quantitative LPG accident analysis. The simulation showed the following results. In case of UVCE(Unconfined Vapor Cloud Explosion), the effect within l0m of the accident spot showed very severe structural damages and even the accident can break the window glasses of the area of 150 m apart from accident spot. In case of TNT corresponding probit analysis, after 10 minutes LPG leaking, $75\%$ window glasses of 40 m distance was expected to be broken. And $16\%$ frames of 20m distance, $10\%$ frames of 40m distance was expected to be collapsed.

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The Usefulness of Al Face Block Fabrication for Reducing Exposure Dose of Thyroid Glands in Mammography (유방촬영 시 갑상샘의 피폭선량 경감을 위한 Al Face Block 제작 및 유용성에 관한 연구)

  • Hong, Eun-Ae;Lee, In-Ja
    • Journal of radiological science and technology
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    • v.36 no.1
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    • pp.11-17
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    • 2013
  • Currently, there are many studies being conducted around the world to reduce exposure dose to radiation for patients to receive medical treatments in a safe environment. We developed and fabricated of this shield that the patients are protected from the radiation and are need of safety control during breast imaging. In this study, for breast imaging, GE Senography 2000D were used and set at SID 65cm, 28kVp, and 63mAs. The measuring instrument was Fluke's Victoreen 6000-529. And we performed Face Block on with 30 patients. The chamber on the actual thyroid glands to take CC and MLO and measure the dosage before and after wearing the Face Block. For the results, after wearing the Face Block, exposure was decreased by 53.8%-100% and 65.8% in average in CC View and by 50%-100% and 60.7% in average in MLO View. The development of the Face Block that practically decreased the exposure dose of thyroid glands, crystalline eyes during breast imaging and reduced the patients' anxiety during breast imaging. The Face Block is expected to improve patients' satisfaction and contribute to reducing patients' exposure dose, but more efforts should be made to reduce exposure dose to medical radiation.