• Title/Summary/Keyword: Safe life

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Novel Oral Anticoagulants for the Treatment of Venous Thromboembolism in Cancer Patients (암환자의 정맥혈전색전증 치료를 위한 새로운 경구용 항응고제)

  • Kim, Joo Hee;Gwak, Hye Sun
    • Korean Journal of Clinical Pharmacy
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    • v.26 no.4
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    • pp.269-282
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    • 2016
  • Venous thromboembolism, encompassing deep vein thrombosis and pulmonary embolism, has increased in cancer patients and adversely affects their prognosis. Low-molecular-weight heparins are recommended as efficacious and safe anticoagulation treatment in cancer patients. However, in practice, oral anticoagulation is preferred, especially if longterm or extended treatment is necessary. Novel oral anticoagulants have recently emerged as an alternative to the standard therapy owing to the ease of administration, predictable anticoagulation effect without the need of laboratory monitoring, and fewer drug interactions. These new agents have been shown as effective and safe for the management of cancer-associated thrombosis in ongoing head-to-head comparative trials. Here we review the advances and limitation of current anticoagulant therapies.

SENTINEL ASIA FOR ENVIRONMENT (SAFE)

  • Takeuchi, Wataru;Akatsuka, Shin;Nagano, Tsugito;Samarakoon, Lal
    • Proceedings of the KSRS Conference
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    • 2008.10a
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    • pp.402-405
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    • 2008
  • This paper is a proposal of Sentinel Asia for Environment (SAFE). The essential to this project is to help environmental agencies in Asia to set up an environmental monitoring system with satellite observation data. It is focused on an environmental issues originated from anthropogenic events detected as land cover and land use change in Asians' daily human life including; agriculture, global warming gas, urban environment and forest resources. It is leaded by Japan Aerospace Exploration Agency (JAXA) along with University of Tokyo and Asian Institute of Technology in Thailand under the umbrella of Sentinel Asia which is dedicated to disaster monitoring issues. It is expected to initiate a information outgoing through WWW for Asian countries to set up their national land information system focusing on environmental changes.

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Study on the Safe Evacuation Management in a Power Supply Disturbed Emergency

  • Suzuki, Nobuyuki;OHASHI, Tsubasa;WHORLOW, James R
    • International conference on construction engineering and project management
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    • 2015.10a
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    • pp.87-91
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    • 2015
  • For construction projects it is imperative that site management gives the highest priority to planning safe site evacuation for all foreseeable emergencies, including earthquakes and typhoons which are often experienced in Japan. This is especially important and even more critical for high risk projects involving underground works, such as Tunneling & Pneumatic Caissons. Based on the safety regulation of underground works, a back-up power supply system must be provided during the construction period at all times. Often, fluorescent lamps with re-chargeable batteries are provided for infrequent emergency cases, however these have a questionable useable life span and thus need careful maintenance and periodical replacement. In this paper we focused on using the phosphorescence materials to indicate the evacuation direction. As a result, it was confirmed that the phosphorescence materials were considered useful in reducing panic and facilitating a controlled evacuation in the event of a total black-out due to power failure.

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Antimicrobial Effects and Mechanism(s) of Silver Nanoparticle (은나노 입자의 항균작용과 작용기작)

  • Hwang, In-Sok;Cho, Jae-Yong;Hwang, Ji-Hong;Hwang, Bo-Mi;Choi, Hye-Min;Lee, June-Young;Lee, Dong-Gun
    • Microbiology and Biotechnology Letters
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    • v.39 no.1
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    • pp.1-8
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    • 2011
  • The antimicrobial effects of silver (Ag) ion or salts are well known. Recently, silver nanoparticle is attracting an interest in a wide variety of fields since it has been known to be safe and effective as an antimicrobial agent against a broad spectrum of microorganisms. Although silver nanoparticle has been applied to various kinds of products owing to its potent antimicrobial activity, the effects of silver nanoparticle on microorganisms and antimicrobial mechanism have not been revealed clearly. In this paper, we summarized the characteristics, antimicrobial activities and mechanisms, cytotoxicity and applicability of silver nanoparticle.

A Study on Interior Flooring Materials for Safe Elderly Nursing Home Environment (안전한 노인요양시설 환경을 위한 실내 바닥마감재에 관한 연구)

  • Chung, Miryum
    • Journal of the Korean housing association
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    • v.25 no.2
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    • pp.19-26
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    • 2014
  • The number of elderly who wants to access to Nursing Homes (NH) will increase due to the rapid aging society and domestic changes. Those who move into NH expect 24/7 care service in safe environment. Providing space free from danger, especially from fall, for the frail elderly is essential. The purpose of this study is to categorize performance needs of flooring materials in the aspect of safety, and analyze materials so that adequate ones for each space in NH can be suggested. Performance needs are as follows; slip resistance (dry/wet), fire resistance, resilience, water resistance, soil retardant, anti-bacterial, gloss, sound absorbtion. maintenance, durability, ease replacement, color and pattern variety, visual and tactual texture, tactile warmth, IAQ, sustainable material (before use), impact to nature (after use). They are categorized under function, economy, sensibility and sustainability. It was found that there are better materials than common ones that has been used repeatedly in NHs, such as vinyl sheets and VCT. In overall, Cork flooring and nylon carpet met all four categories, followed by wool carpet, rubber and linoleum. For bedroom, wood flooring, Cork, rubber, wool carpet, nylon carpets were suggested. In bathroom with shower, rubber, vinyl sheet and porcelain tiles were safe materials. As living/dining room and corridor floors, wool carpet, nylon carpet, cork flooring would be excellent as they are resilient and durable. The result of this paper can be used by both NH managers and material companies, resulting better quality of life of the elderly by providing safe environment.

A Study on the Establishment of Rules of Safe Navigation and Management for Gyeongin Ara Waterway (경인 아라뱃길 안전운항 및 관리규칙 제정에 관한 연구)

  • Yun, Giw-Ho;Kim, Jin-Kwon
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.17 no.3
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    • pp.235-243
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    • 2011
  • Gyeongin Ara Waterway will be open on Oct., 2011, Which is the first inland artificial waterway constructed in Korea. There have been arguments about the environmental issues and economic effectiveness, however, it's now time to focus on the safety of navigation at the waterway to protect human life, property and environment. Therefore this paper aims at examining the establishment of the rule of safe navigation and management for the safe and effective management of the waterway and tries to draft the rules based on these examinations. The draft rule consists of 7 chapters, which are general rules, general rules on navigation, specific rules on navigation, general restrictions, emergency response, restrictions on navigation and penalties in consideration of the characteristic of Gyeongin Ara Waterway and regulations on navigation in major canals in the world.

Development of Comic Books and an Animation as Dietary Education Materials for Children (어린이 식생활 교육을 위한 만화와 애니메이션의 개발)

  • Kim, Bo-Kyung;Park, Hae-Ryun;Kim, Jeong-Weon
    • Korean Journal of Community Nutrition
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    • v.13 no.5
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    • pp.630-639
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    • 2008
  • The purpose of this study was to develop children-friendly comic books and animation for dietary education of 3rd or 4th grade elementary students. Through a literature review on current dietary problems and dietary education for children, 15 educational themes were chosen on both healthy eating and safe dietary life. Comic books and animation were developed based on the themes by the brainstorming and help of professional animators, and they were applied and evaluated in the field. The developed comic books and animation, with its own characters, proved to be of high quality and effective educational materials for children's healthy and safe eating. Compared with the reference group, the tested group has shown a significant improvement in dietary knowledge and attitude (p < 0.05). And both parents (level of understanding 4.29, level of interest 4.49, level of usefulness 4.46, level of design satisfaction 3.95 in 5-point Likert scale) and children (level of understanding 4.63, level of interest 4.57, level of usefulness of 1st comic book 4.44, 2nd comic book 4.49, level of design satisfaction 4.06, level of usefulness for knowledge pages 4.22 in 5-point Likert scale) have shown high levels of interests and satisfaction. Therefore, these materials could be utilized as effective educational materials for elementary students in school lunch time, extra-curricular activities, or after school programs.

Fatigue Test and Evaluation of Landing Gear (착륙장치 피로 시험평가)

  • Lee, Sang-Wook;Lee, Seung-Gyu;Shin, Jeong-Woo;Kim, Tae-Uk;Kim, Sung-Chan;Hwang, In-Hee;Lee, Je-Dong
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.36 no.10
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    • pp.1181-1187
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    • 2012
  • For the fatigue design of aircraft landing gear, the safe-life approach is applied. Structural defects such as cracks or detrimental deformations should not occur under the fatigue load spectrum depicting the entire lifetime usage of the aircraft. In the design phase, the fatigue life of the landing gear is estimated analytically by adopting the stress-based approach because the fatigue of aircraft landing gear is generally high-cycle fatigue. This utilizes S-N curves that are factored to produce design curves that account for the scatter and surface finish of the material. In the test and evaluation phases, a fatigue test should be conducted for full-scale landing gear to substantiate the fatigue design requirement in the end. In this study, the procedure for the fatigue test and evaluation of aircraft landing gear is presented with real application cases.

Innovative Application of Cold Plasma Technology in Meat and Its Products

  • Dinesh D. Jayasena;Taemin Kang;Kaushalya N. Wijayasekara;Cheorun Jo
    • Food Science of Animal Resources
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    • v.43 no.6
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    • pp.1087-1110
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    • 2023
  • The growing demand for sustainable food production and the rising consumer preference for fresh, healthy, and safe food products have been driving the need for innovative methods for processing and preserving food. In the meat industry, this demand has led to the development of new interventions aimed at extending the shelf life of meats and its products while maintaining their quality and nutritional value. Cold plasma has recently emerged as a subject of great interest in the meat industry due to its potential to enhance the microbiological safety of meat and its products. This review discusses the latest research on the possible application of cold plasma in the meat processing industry, considering its effects on various quality attributes and its potential for meat preservation and enhancement. In this regard, many studies have reported substantial antimicrobial efficacy of cold plasma technology in beef, pork, lamb and chicken, and their products with negligible changes in their physicochemical attributes. Further, the application of cold plasma in meat processing has shown promising results as a potential novel curing agent for cured meat products. Understanding the mechanisms of action and the interactions between cold plasma and food ingredients is crucial for further exploring the potential of this technology in the meat industry, ultimately leading to the development of safe and high-quality meat products using cold plasma technology.

Determining Kimbab Shelf-life with a HACCP System (HACCP을 적용하여 생산한 김밥의 유통기한 설정)

  • Lee, Jin-Hyang;Bae, Hyun-Joo
    • Korean journal of food and cookery science
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    • v.27 no.2
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    • pp.61-71
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    • 2011
  • This study was conducted to estimate the shelf-life of Kimbab manufactured using a Hazard Analysis and Critical Control Point (HACCP). We performed a microbiological verification after applying the HACCP plan to Kimbab. Additionally, the shelf-life of Kimbab at each holding temperature was calculated as a regression equation between the aerobic plate counts and holding time during the storage period. The critical control points of the HACCP plan, that were applied to Kimbab, included: cold-holding of refrigerated foods, checking the endpoint cooking temperature of heated food, and cold-holding of cooked foods. As a result of the microbiological verification of Kimbab, the aerobic plate counts averaged 3.46 log CFU/g. In contrast, the coliforms, E. coli, Staphylococcus aureus, and Salmonella spp. were not detected in any of the samples. The estimated shelf-life of Kimbab was calculated to be 45 hours at $10^{\circ}C$, 29 hours at $15^{\circ}C$, 6 hours at $25^{\circ}C$ and 3 hours at $35^{\circ}C$. In conclusion, manufacturers should apply a prerequisite program and a HACCP system for a safe consumption of ready-to-eat foods and label products with a proper shelf-life. Distributors should control the proper holding time-temperature until sale and consumers should eat immediately after purchasing ready-to-eat foods.