• Biomedical Science Letters
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• v.19 no.3
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• pp.188-194
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• 2013

Ulcerative colitis (UC) is an inflammatory bowel disease, which is a chronic gastrointestinal disorder. Adenophorae Radix (AR) has been used as a traditional medicine for various diseases including strengthening cardiac function, allaying a fever, and easing pain and cough. However, the regulatory effects of AR in intestinal inflammation are not yet understood. This study attempted to determine the effect of AR in dextran sulfate sodium (DSS) - induced colitis in mice. The colitis mice were induced by drinking water containing 5% DSS for 7 days. The results showed that mice treated with DSS showed remarkable clinical signs, including weight loss, and reduced colon length. Administration of AR attenuated weight loss, colon shortening and inhibited the levels of interleukin (IL) - 6 in DSS - treated colon tissues. These results provide experimental evidence that AR might be a useful therapeutic medicine for patients with UC.

• Biomedical Science Letters
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• v.19 no.4
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• pp.285-294
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• 2013

Chungyangeum (CYE) is a newly designed herbal drug formula for the purpose of treating atopic dermatitis. The aim of the present study is to elucidate whether and how CYE modulates the allergy inflammation in vitro and in vivo. We investigate to ascertain the pharmacological effects of CYE on both compound 48/80 or histamine-induced scratching behaviors and 2, 4-dinitrochlrobenzene (DNCB)-induced atopic dermatitis in mice. Additionally, we attempted to determine the effects of CYE on lipopolysaccharide (LPS)-induced inflammatory responses in macrophages. The findings of this study demonstrated that CYE reduced compound 48/80 or histamine-induced scratching behaviors and DNCB-induced atopic dermatitis in mice. The CYE inhibited the production of inflammatory cytokines as well as the activation of NF-${\kappa}B$ and caspase-1 in stimulated macrophages. Collectively, the findings of this study provide us with novel insights into the pharmacological actions of CYE as a potential molecule for use in the treatment of allergic inflammation diseases.

• Journal of Korean Academy of Nursing Administration
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• v.21 no.5
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• pp.469-479
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• 2015

Purpose: The purpose of this study was to compare hospitalized patients in comprehensive nursing care units and general care units as to satisfaction with nursing care and factors influencing their intent to revisit the hospital. Methods: A cross-sectional study was conducted with 178 patients who had been hospitalized in a comprehensive nursing care unit and a general care unit in one hospital. Participants completed self-report questionnaires. Data were analyzed using SPSS 21.0. Results: There was a significant difference between the comprehensive nursing care unit and general care unit for intent to revisit the hospital (p=.036). Factors influencing intent to revisit the hospital for patients in the comprehensive nursing care unit were 'satisfaction with nursing care' (p<.001) and 'use of additional costs for comprehensive nursing care' (p=.041). The factor influencing intent to revisit hospital for patients in the general care unit was 'satisfaction with nursing care' (p<.001). Conclusion: Findings indicate that comprehensive nursing care service in which all care is provided by nursing staff only, without family or private caregivers, increases intent to revisit the hospital. These results can be used as the foundation of reviewing the operation and expansion of comprehensive nursing care service.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.58 no.3
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• pp.205-213
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• 2022

The experimental fish transplanted from China in 2015 was used after seedling production and cultivated. Breeding management for experiment was carried out from October 2020 to February 2021. Also, it succeeded in inducing artificial maturation three to four months earlier than wild broodstock and secured good quality fertilized eggs. The average size of fertilized eggs was 1.22 mm, at 20℃ Blastodisc (15 minutes post-fertilization), 2 cell (50 minutes), 4 cell (1 hours), 8 cell (2 hours), 16 cell (2 hours and 30 minutes), 32 cell (2 hours and 50 minutes), morula (3 hours), blastula (8 hours), gastrula (15 hours), skull formation (20 hours), organ formation (30 hours) and hatching yolk larvae stage (35 hours). The total length of the just hatched larvae were 2.50 ± 2 mm, and then gain growth of 42.5 mm by 60 days, reaching 45 ± 5 mm.

• Journal of Korean Physical Therapy Science
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• v.7 no.2
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• pp.597-605
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• 2000

There has been several usual ways to cure pain in osteological muscle: use oral medicine or injection, or apply medicine to a sore place. The purpose of this study was to examine, by using thermometer and digital infrared thermographic imaging, how much the permeation of aceclofenac, an anodyne and antiphlogistic, into sore skin brought a change to skin temperature after that was' applied to it. The findings of this study were as below; 1. A cream made of aceclofenac yielded $0.61^{\circ}C$ difference in temperature, but the difference wasn't statistically significant. 2. An aceclofenac to which oleic acid was added went through microemulsion and applied, and there was $0.3^{\circ}C$ change in temperature, the biggest significant difference(P<.05), after approximately 15 minutes passed. 3. An aceclofenac to which labrasol was added went through microemulsion and applied, and there was a growing rise in temperature with the lapse of time. After 30 minutes passed, the final temperature showed $1.25^{\circ}C$ rise, which was a significant change(P<.05). 4. As the temperature was measured by digital infrared thermographic imaging, there was about $3.97^{\circ}C$ fall, the biggest change, which was significant(P<.05). The findings of this study suggested that the application of aceclofenac to sore skin caused a change in skin temperature, as that permeated into it.

• Korean Journal of Agricultural Science
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• v.41 no.2
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• pp.107-112
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• 2014

Coloring agents in food materials plays important roles in the development of attractive products as well as in the functionality of food such as antioxidant or vitamin supplementation. Carrot has been used as an orange coloring agent in the decoration of food but also a major source of vitamin A complex. Though orange has been considered a typical color of carrot, the Rainbow carrot has been developed recently, which exhibit the various colors such as red, pale yellow, purple, orange or their mixtures. After categorization onto 8 groups by their colors, vitamin A complex (${\beta}$-carotene, lycopene and lutein) and soluble sugars (glucose, fructose, and sucrose) have been analyzed in carrots. The ${\beta}$-carotene was abundant in the groups of orange (Group-O) or groups with the orange color (group-OP, and group-YOP). The content of lycopene content was exclusively high in the red color carrot (group-R). The highest lutein contents were observed from the yellow-purple (group-YP) group. Meanwhile, little amounts of lycopene and ${\beta}$-carotene were observed in yellow-purple (group-YP) nor yellow (group-Y) on yellow (group-Y). Among the reducing sugars in 'rainbow carrots', the amount of sucrose was two times higher than those of fructose and glucose. However, the content of glucose, fructose and sucrose as well as the total reducing sugars did not differ between color groups suggesting little variations on their tastes.

• The Journal of Korean Academy of Prosthodontics
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• v.58 no.4
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• pp.378-384
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• 2020

For patients with unstable mandibular movements and centric relation of the mandible due to long-term use of ill-fitting dentures, the successful fabrication of new dentures is challenging. Before fabrication new dentures, registration of centric relation is the critical point in such cases. In this case, treatment dentures with a flat occlusal table were used to stabilize mandibular movements and to register centric relation. In order to reflect the patient's jaw relation and vertical dimension obtained through the treatment dentures to the final denture, the treatment dentures were digitally duplicated, and impressions and jaw relations were obtained using the duplicated therapeutic dentures. The clinical results were satisfactory on the aspect of aesthetic and masticatory functioned.

• Journal of Korean Society of Rural Planning
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• v.19 no.4
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• pp.33-46
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• 2013

The present study aims to provide an analytical framework for achieving aid and development effectiveness of agricultural cooperation with a demand-oriented perspective. This paper pays particular attention to categorize the stages of agricultural development of African recipients to identify demands for agricultural aid of the categorized groups. To do so, first of all, it establishes theoretical background to apply the demand-oriented concept and utilize the phase of agricultural development as an alternative for aid and development effectiveness. On the basis of the theoretical robustness, it conducts a series of analyses to categorize the African recipients by the development stages, incorporating factor analysis, cluster analysis and comparison between the present-future agricultural development levels. The findings propose analysis indicators for phase of agricultural development and clustered results including 18 countries of KAFACI members and priority countries in Africa. In addition to the practical application of the results, the methodological flow can be used as steps for sketching a future roadmap to construct the demand-oriented ODA(Official Development Assistance) plan. This paper also offers implications regarding ODA strategy of Korea in response to the phase of agricultural development and the aid demands.

• The Journal of Korean Medicine
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• v.38 no.3
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• pp.30-42
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• 2017

Objectives: The purpose of this study was to investigate the effects of Angelica gigas Nakai extract(AGNE) and Bacillus polyfermenticus KJS-2 (BP2) on atopic dermatitis (AD) induced by 2, 4-dinitrochlorobenzene (DNCB) in mice. Methods: In the experiment, we divided mice into four groups: a control group, a DNCB group, an AGNE group, and an AGNE+BP2 group. Then we examined the changes in scratching frequency, clinical aspects on dorsum skin, immunoglobulin (IgE), cytokines ($TNF-{\alpha}$, IL-6) and expression of COX-2. Resutls: From the experiment, the scratching frequency was significantly dropped in AGNE group and AGNE+BP2 group. Clinical observations of dorsum skin, there were a severe keratotic lesion and drop of dead skin cell in DNCB group, but symptoms of AD were decreased 39.6% in AGNE group and 49.6% in AGNE+BP2 group during 3 weeks. IgE, $TNF-{\alpha}$ and IL-6 were decreased significantly in both AGNE and AGNE+BP2 group. Expression of COX-2 was also decreased significantly in both groups. Conclusions: In conclusion, these data suggest that AGNE can decrease symptoms of AD and BP2 makes AGNE more effective. So AGNE can be useful herbal therapy for AD.

• Korean Journal of Health Education and Promotion
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• v.25 no.1
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• pp.83-104
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• 2008

Objectives: Community-Based Participatory Research (CBPR) is a kind of health promotion approach to increase social cohesion and sense of community, which has built the collaborated partnership in all phases. This has the co-ownership of research objectives and knowledges produced by residents, and the outcome was taken to enhance community empowerment. This study performed to embody CBPR, which had regulated collective health status approached by social epidemiology. Methods: Reference review had been exercised focused on CBPR books and papers published since 1990. Our interests were aimed at its paradigm and methodological issues. Particularly, we problematized its feasibility in the social and behavioral foundations of pubic health. Results: According to the review, CBPR shared critical understanding and decision-making related to their community development including health status. Therefore, it was strength-based approach in spite of scientific dichotomy. CBPR created social cohesion and community empowerment with all participants, because it sublated contradiction between subjectivism and objectivism. Conclusions: The success of CBPR needs what we so called trust, democracy, collaboration, devotion, and consensus of equity. Despite these factors, CBPR may be a methodological transition to prepare some intervention of health inequality. This is because it does emphasize a mixture of theory and praxis to manage vulnerable people in community.