• Title/Summary/Keyword: Sa 2.5

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The Changes of Arterial Oxygen Saturation During Sleep in Chronic Obstructive Pulmonary Disease Patients (만성 폐쇄성 폐질환 환자에서 수면중 동맥혈 산소 포화도의 변화)

  • Jeong, Ki-Ho;Choi, Hyung-Seok;Hyun, In-Gyu;Choi, Dong-Chull;Yoo, Chul-Gyu;Kim, Young-Whan;Han, Sung-Koo;Shim, Young-Soo;Kim, Keon-Youl;Han, Yong-Chol
    • Tuberculosis and Respiratory Diseases
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    • v.38 no.3
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    • pp.255-261
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    • 1991
  • Frequently patients with chronic obstructive pulmonary disease have lowered arterial oxygen saturation in daytime. During sleep, they are apt to experience additional hypoxemia. These episode of nocturnal hypoxemia are usually associated with periods of relative hypoventilation. Noctunal hypoxemia may be associated with cardiac arrhythmia and with acute increase in pulmonary arterial pressure and may be implicated in the development of chronic pulmonary hypertension and cor pulmonale. We selected 14 patients with chronic obstructive pulmonary disease, 9 with emphysema dominant type and 5 with chronic bronchitis dominant type, to examine the frequency and severity of nocturnal hypoxemia and the effect of oxygen in prevention of nocturnal hypoxemia. The results were as follows; 1) On PFT, FVC, $FEV_1$, and $FEV_1$/FVC showed no significant difference between the emphysema dominant type (pink puffers, PP) and the chronic bronchitis dominant type (blue bloaters, BB). But DLCO/VA for the PP group was $45.7{\pm}15.1%$ which was significantly different from BB group, $82.4{\pm}5.6%$. 2) The daytime arterial oxygen saturation ($SaO_2$) and the lowest $SaO_2$, during sleep for the BB group were significantly lower than for the PP group. 3) The hypoxemic episodes during sleep were more frequent in BB group and the duration of hypoxemic episode was longer in BB group. 4) In both group studied, although there was a tendency for a lower L-$SaO_2$ (the lowest $SaO_2$, during sleep), an increase in hypoxemic episodes and duration as the daytime $SaO_2$, fell lower, the only parameter which showed significant correlation was daytime $SaO_2$, and the frequency of hypoxemic episodes in the PP group (r=-0.68, P<0.05). 5) In PP group, with oxygen supplementation, L-$SaO_2$, during sleep showed significant increase, and there was a tendency for the frequency of hypoxemic episodes and duration to fall but it was not significant. 6) In BB group, oxygen supplementation significantly increased the L-$SaO_2$ during sleep and also significantly decreased the frequency and duration of hypoxemic episode. From these results, we can see that oxygen supplementation during sleep can prevent the decrease in $SaO_2$ to some extent and that this effect of oxygen can be seen more prominently in the BB group.

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The Effect of Sa-Am Stomach Tonifying Acupuncture on Radial Pulse in Healthy Human Subjects (위정격(胃正格) 자침이 정상 성인의 맥파(脈波)에 미치는 영향)

  • Choi, Joo Young;Kang, Jae Hui;Yim, Yun Kyong;Lee, Hyun
    • Journal of Acupuncture Research
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    • v.29 no.6
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    • pp.57-71
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    • 2012
  • Objectives : The purpose of this study is to find the effects of Sa-Am stomach tonifying acupuncture on radial pulse through the parameters difference. Methods : Forty healthy subjects participated in this study, acupuncture group and control group were divided. Radial pulse were measured using 3 dimensional pulse imaging system(DMP-3000). 19 parameters that significantly changed were selected after comparing between acupuncture group and control group. Then, 19 parameters were analyzed before, immediately after, 30 minutes after and 60 minutes after acupuncture in acupucture group. Results : 1. Heart rate, pulse period, T/T1, T2/T, T4/T, T5/T, T-T4, (T-T4)/T and T4/(T-T4) significantly changed after acupuncture. 2. H1 Amplitude, H2 Amplitude, H4 Amplitude and H5 Amplitude significantly changed after acupuncture. 3. Area of Pulse Wave, Systolic Pulse Area, Diastolic Pulse Area and Area of W significantly changed after acupuncture. 4. AIx/HR significantly changed after acupuncture. Conclusion : Stomach Tonifying Acupuncture exerts an influence on radial pulse parameters. Further radial pulse change study on various acupuncture treatment is required.

Functional Analysis of Pepper Cys2/His-Type Zinc-Finger Protein Promoter Region in Response to Bacterial Infection and Abiotic Stresses in Tobacco Using Agrobacterium-Mediated Transient Assay

  • Kim, Sang-Hee;Hwang, Byung-Kook
    • The Plant Pathology Journal
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    • v.21 no.1
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    • pp.39-46
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    • 2005
  • The promoter region flanking the 5’ CAZFP1 coding region was isolated from the genomic DNA of Capsicum annuum. To identify the upstream region of the CAZFP1 gene required for promoter activity, a series of CAZFP1 promoter deletion derivatives was created. Each deletion construct was analyzed by Agrobacterium-mediated transient transformation in tobacco leaves after infection by Pseudomonas syringae pv. tabaci, or treatment with methyl jasmonate (MeJA), ethylene, abscisic acid (ABA), salicylic acid (SA), cold and wounding. Promoter fragments of 685 bp or longer showed 7-fold or greater induction after P. s. pv. tabaci infection and MeJA treatment. The CAZFP1 full-length promoter (-999 bp) also showed 6-fold induction in response to ethylene. The transiently transformed tobacco leaves with the CAZFP1 full length promoter fused-GUS gene showed more than 5-fold induction in response to SA, ABA and cold. These results suggest that the CAZFP1 promoter contains responsive elements for pathogen, MeJA, ethylene, SA, ABA and cold.

A Comparative Study on Sa-Am's Ohaeng-acupuncture and Liuqi-acupuncture (오행침(五行鍼)을 응용한 육기침(六氣鍼)에 관한 연구)

  • Kim, Jae-hong;Cho, Myung-rae
    • Journal of Acupuncture Research
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    • v.20 no.1
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    • pp.61-73
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    • 2003
  • Objective: The purpose of this study is to compare Sa-Am's Ohaeng-acupuncture(舍巖五行鍼法) with Linqi-aupuncture(六氣鍼法)-the transforms of Sa-Am's Ohaeng-acupuncture. Methods : Zheng Ge(正格), Sheng(勝格), Han Ge(寒格), Re Ge(熱格) of Sa-Am's Ohaeng-acupuncture compared with Liuqi-acupuncture(六氣鍼法)-therapy form invigoration and purgation of five zang-fu's wind. heat, dapness, dryness and cold(風熱濕燥寒). Results: 1. Liuqi-acupuncture used five-su points(五兪穴) and Zi-Ta Jing Bu Xie(自他經補瀉). 2. Liuqi-acupuncture is reinforced or reduced itself-point of itself-meridian(自經自穴) in therapy for invigoration and purgation. 3. Liuqi-acupuncture is therapy for invigoration and purgation of five zang-fu's wind, hear, dampness, dryness and cold(風熱濕燥寒). 4. Zheng Ge is similar to Bu-fa, Sheng Ge is similar to Xie-fa in Qu-xue of Ta-jing. The Qu-xue of interrestraining relations is the same, but that of interdependent relation is the difference in Qu-xure of Zi-jing. 5. Han Ge and Re Ge is similar to Re Bu Xie fa in Qu-xue fo Zi-jing but is different to in Ta-zing. For example, Han Ge is Shaofu(Bu), Yingu(Xie) but Re Ge is Shaofu(Xie), Yingu(Bu).

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Comparison of applicability of current transition temperature shift models to SA533B-1 reactor pressure vessel steel of Korean nuclear reactors

  • Yoon, Ji-Hyun;Lee, Bong-Sang
    • Nuclear Engineering and Technology
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    • v.49 no.5
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    • pp.1109-1112
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    • 2017
  • The precise prediction of radiation embrittlement of aged reactor pressure vessels (RPVs) is a prerequisite for the long-term operation of nuclear power plants beyond their original design life. The expiration of the operation licenses for Korean reactors the RPVs of which are made from SA533B-1 plates and welds is imminent. Korean regulatory rules have adopted the US Nuclear Regulatory Commission's transition temperature shift (TTS) models to the prediction of the embrittlement of Korean reactor pressure vessels. The applicability of the TTS model to predict the embrittlement of Korean RPVs made of SA533B-1 plates and welds was investigated in this study. It was concluded that the TTS model of 10 CFR 50.61a matched the trends of the radiation embrittlement in the SA533B-1 plates and welds better than did that of Regulatory Guide (RG) 1.99 Rev. 2. This is attributed to the fact that the prediction performance of 10 CFR 50.61a was enhanced by considering the difference in radiation embrittlement sensitivity among the different types of RPV materials.

Dielectric Breakdown Behavior of Anodic Oxide Films Formed on Pure Aluminum in Sulfuric Acid and Oxalic Acid Electrolytes

  • Hien Van Pham;Duyoung Kwon;Juseok Kim;Sungmo Moon
    • Journal of the Korean institute of surface engineering
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    • v.56 no.3
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    • pp.169-179
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    • 2023
  • This work studies dielectric breakdown behavior of AAO (anodic aluminum oxide) films formed on pure aluminum at a constant current density in 5 ~ 20 vol.% sulfuric acid (SA) and 2 ~ 8 wt.% oxalic acid (OA) solutions. It was observed that dielectric breakdown voltage of AAO film with the same thickness increased with increasing concentration of both SA and OA solutions up to 15 vol.% and 6 wt.%, respectively, above which it decreased slightly. The dielectric breakdown resistance of the OA films appeared to be superior to that of SA films. After dielectric breakdown test, cracks and a hole were observed. The crack length increased with increasing SA film thickness but it did not increase with increasing OA film thickness. To explain the reason why shorter cracks formed on the OA films than the SA films after dielectric breakdown test, the generation of tensile stresses at the oxide/metal interface was discussed in relation to porosity of AAO films obtained from cross-sectional morphologies.

Analysis of Improvement on Delay Failures in Separated Driving-line Sense Amplifier (구동라인분리 센스앰프의 딜레이페일 개선 효과에 대한 분석)

  • Dong-Yeong Kim;Su-Yeon Kim;Je-Won Park;Sin-Wook Kim;Myoung Jin Lee
    • Journal of IKEEE
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    • v.28 no.1
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    • pp.1-5
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    • 2024
  • To improve the performance of DRAM, it is essential to reduce sensing failures caused by mismatch in SA. Unlike flip failures, delay failures can be degraded, especially when high-speed operation is required, making it a critical consideration in the design of next-generation memory. While conventional SA operates with all transistors starting amplification simultaneously, SDSA selectively activates only two transistors that output BLB, thus alleviating offset. In this paper, we validate the superior performance of SDSA in mitigating delay failures through simulations. It was confirmed that SDSA exhibits approximately a 90 % reduction in delay failures compared to conventional SA.

Analysis of Housing Management as shown in Sa-So-Jul (사소절 부의에 나타난 주생활 관리에 관한 내용분석)

  • 주영애
    • Journal of the Korean Home Economics Association
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    • v.35 no.1
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    • pp.75-84
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    • 1997
  • This study is a content analysis of housing management as shown in the Sa-so-jul. This book is written by Lee, Duk Moo in 1741 during Chosun dynasty. This contents relates to life management. The contents of housing management were storage cleaning and equipment management. The major findings this study are as follows. 1) Housing management was charged with woman. 2) Contents of housing managements were storage cleaning and equipment management. 3) It goes into detial. 4) Housing management relates to clothing & food management. 5) In the traditional society woman have to upright in her actions which is housing management. But today things are not what they used to be. A woman does not think anymore to do work housekeeping. But an idea of life does not change. So it is following as shown in the Sa-so-jul. 1) We must to clean for housing management. 2) Housing management is for my family and our neighborhood.

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Screening and Development of Novel Herbal Medicine for Bone Healing Treatment (골유합 촉진 치료제 개발을 위한 수종의 한약재 활성 검색)

  • Lee, Jae-Dong;Baek, Yong-Hyeon;Choi, Do-Young;Huh, Jeong-Eun;Yang, Ha-Ru;Woo, Hyun-Su;Park, Dong-Suk
    • Journal of Acupuncture Research
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    • v.24 no.5
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    • pp.13-22
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    • 2007
  • Objectives : The differentiation of osteoblasts is controlled by various growth factors and matrix protein expressed in bone. The aim of this study was to investigate the effects of many herbs medicine(KHBJs) for bone healing that induces osteogenic activity in human osteoblast-like SaOS-2 cells. Methods : The osteogenic effects of KHBJs were evaluated by using cell proliferation(WST-8) assay, alkaline phosphatase(ALP) activity assay, colorimetric analysis of vascular endothelial growth factor(VEGF) expression in human osteoblast like SaOS-2 cell. Also, osteogenic activity of KHBJ fractions(KHBJB and KHBJR) by activity guided fractionation were evaluated. Results : About 7 KHBJs had effect on the proliferation of osteoblast like SaOS-2 cells, and dose-dependently increased alkaline phosphatase(ALP) activity. KHBJs markedly increased expression for VEGF. Fractionated KHBJs(KHBJB or KHBJR) not enhanced more than KHBJs on osteogenic activity in SaOS-2 cells. Conclusions: This study found that 7 KHBJs had effect on proliferation, ALP activity, and VEGF expression in osteoblast like SaOS-2 cells. These results propose that KHBJs can play an important role in osteoblastic bone formation, and may possibly lead to the development of bone-forming drugs.

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Is Lymph Node Size a Reliable Factor for Estimating Lymph Node Metastasis in Early Gastric Cancer?

  • Kim, Dong Jin;Kim, Wook
    • Journal of Gastric Cancer
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    • v.18 no.1
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    • pp.20-29
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    • 2018
  • Purpose: Pre-operative lymph node (LN) size is a valuable parameter for determining treatment strategy for gastric cancer. However, a correlation between LN size and metastasis has not been established. Materials and Methods: Thirty-six LN-positive (LNP) and matched 36 LN-negative (LNN) patients were included, and pathology slides of the LNs of these patients were reviewed. All the LNs were measured along the long-axis (LA) and short-axis (SA), manually. Results: Average retrieved LNs were $37.3{\pm}19.8$ and $40.5{\pm}11.6$ in the LNN and LNP groups, respectively. In total 2,800 LNs, including 136 metastatic LNs (MLNs) and 2,664 non-metastatic LNs (nMLNs), were evaluated. Mean length was significantly more in MLNs along both, the LA and SA (MLN_LA vs. nMLN_LA: $4.97{\pm}3.84$ vs. $3.37{\pm}2.40mm$, MLN_SA vs. nMLN_SA: $3.86{\pm}3.19$ vs. $2.43{\pm}1.59mm$; P<0.001). However, 92.6% (126/136) and 95.6% (130/136) of MLNs were <10 mm along the LA and SA, respectively. In addition, only 22.2% of the LNP group exhibited an MLN as the largest LN. Conclusions: Pre-operative multi-detector computed tomography has limited ability in estimating the presence of metastasis in LNs because most MLNs are less than 10 mm, and only a small proportion of the LNP group exhibits an MLN as the largest MLN.