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[Retraction] Preparation of Methyl methacrylate/styrene Core-shell Latex by Emulsion Polymerization ([논문 철회] 유화중합에 의한 Methyl methacrylate/styrene계 Core-shell 라텍스 입자 제조에 관한 연구)

  • Kang, Don-O;Lee, Nae-Woo;Seul, Soo-Duk;Lee, Sun-Ryong
    • Elastomers and Composites
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    • v.37 no.1
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    • pp.21-30
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    • 2002
  • Core-shell polymers of methyl methacrylate/styrene pair were prepared by sequential emulsion polymerization in the presence of sodium dodecyl benzene sulfonate(SDBS) as an emulsifier using ammonium persulfate(APS) as an initiator. The characteristics of these core-shell polymers were evaluated. Core-shell composite latex has the both properties of core and shell components in a particle, where as polymer blonds or copolymers show a combined properties from the physical properties or two homopolymers. This unique behavior of core-shell composite latex can be used in many industrial fields. However, in preparation of core-shell composite latex, several unexpected phenomina are observed, such as, particle coagulation, low degree of polymerization, and formation of new particles during shell polymerization. To solve the disadvantages, we studied the effects of surfactant concentrations, initiator concentrations, and reaction temperature on the tore-shell structure or PMMA/PSt and PSt/PMMA. Particle size and particle size distribution were measured by using particle size analyzer, and the morphology of the core-shell composite latex was observed by using transmission electron microscope. Glass transition temperature($T_g$) was also measured by using differential scanning calorimeter. To identify the core-shell structure, pH of the composite latex solutions were measured.

Method Development for the Profiling Analysis of Urine Globotriaosylceramide (Gb3) for the Screening of Fabry Disease by Tandem Mass Spectrometry (ESI-MS/MS를 이용한 소변 중 Globotriaosylceramide(Gb3)의 정량 및 임상 응용; 패브리병(Fabry) 진단)

  • Yoon, Hye-Ran;Cho, Kyung-Hee;Kang, Seung-Woo;Kwon, Young-Joo;Jeong, Choon-Sik;Lee, Yong-Soo
    • YAKHAK HOEJI
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    • v.51 no.2
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    • pp.96-102
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    • 2007
  • Measurement of globotriaosylceramide (Gb3, ceramide trihexoside) in urine has clinical importance for monitoring after enzyme replacement therapy in Fabry disease patients. The disease is an X-linked lipid storage disorder that results from a deficiency of the enzyme ${\alpha}$-galactosidase A (${\alpha}$-Gal A). The lack of ${\alpha}$-Gal A causes an intracellular accumulation of glycosphingolipids, mainly Gb3. A simple, rapid, and highly sensitive analytical method for Gb3 in urine was developed without labor-extensive pre-treatment by electrospray ionization MS/MS (ESI-MS/MS). Only simple 5-fold dilution of urine is necessary for the extraction and isolation of Gb3 in urine. Gb3 in diluted urine was dissolved in dioxane containing C17:0 Gb3 as an internal standard. After centrifugation it was directly injected and analyzed through guard column by in combination with multiple reaction monitoring mode of ESI-MS/MS. Eight isoforms of Gb3 were completely resolved from urine matrix. C24:0 Gb3 occupied 50% of total Gb3 as a major component in urine. Linear relationship for Gb3 isoforms was found in the range of 0.005${\sim}$5.0 ${\mu}$g/ml. The limit of detection (S/N=5) was 0.005 ${\mu}$g/ml and limit of quantification was 0.05 ${\mu}$g/ml for C24:0 Gb3 with acceptable precision and accuracy. Correlation coefficient of calibration curves for 8 Gb3 isoforms ranged from 0.9598 to 0.9975. This method could be useful for rapid and sensitive 1st line Fabry disease screening, monitoring and/or diagnostic tool for Fabry disease.

AN ELECTROCHEMICAL STUDY ON THE CORROSION RESISTANCE OF THE VARIOUS IMPLANT METALS (수종 임플랜트 금속의 내식성에 관한 전기화학적 연구)

  • Jeon Jin-Young;Kim Yung-Soo
    • The Journal of Korean Academy of Prosthodontics
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    • v.31 no.3
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    • pp.423-446
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    • 1993
  • Titanium and its alloys are finding increasing use in medical devices and dental implants. The strong selling point of titanium is its resistance to the highly corrosive body fluids in which an implant must survive. This corrosion resistance is due to a tenacious passive oxide or film which exists on the metal's surface and renders it passive. Potentiodynamic polarization measurement is one of the most commonly used electro-chemical methods that have been applied to measure corrosion rates. And the potentiodynamic polarization test supplies detailed information such as open circuit, rupture, and passivation potential. Furthermore, it indicates the passive range and sensitivity to pitting corrosion. This study was designed to compare the corrosion resistance of the commonly used dental implant materials such as CP Ti, Ti-6A1-4V, Co-Cr-Mo alloy, and 316L stainless steel. And the effects of galvanic couples between titanium and the dental alloys were assessed for their useful-ness-as. materials for superstructure. The working electrode is the specimen , the reference electrode is a saturated calomel electrode (SCE), and the counter electrode is made of carbon. In $N_2-saturated$ 0.9% NaCl solutions, the potential scanning was performed starting from -800mV (SCE) and the scan rate was 1 mV/sec. At least three different polarization measurements were carried out for each material on separate specimen. The galvanic corrosion measurements were conducted in the zero-shunt ammeter with an implant supraconstruction surface ratio of 1:1. The contact current density was recorded over a 24-hour period. The results were as follows : 1. In potential-time curve, all specimens became increasingly more noble after immersion in the test solution and reached between -70mV and 50mV (SCE) respectively after 12 hours. 2. The Ti and Ti alloy in the saline solution were most resistant to corrosion. They showed the typical passive behavior which was exhibited over the entire experimental range. Therefore no breakdown potentials were observed. 3. Comparing the rupture potentials, Ti and Ti alloy had the high(:st value (because their break-down potentials were not observed in this study potential range ) followed by Co-Cr-Mo alloy and stainless steel (316L). So , the corrosion resistance of titanium was cecellent, Co-Cr-Mo alloy slightly inferior and stainless steel (316L) much less. 4. The contact current density sinks faster than any other galvanic couple in the case of Ti/gold alloy. 5. Ag-Pd alloy coupled with Ti yielded high current density in the early stage. Furthermore, Ti became anodic. 6. Ti/Ni-Cr alloy showed a relatively high galvanic current and a tendency to increase.

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A Study on Carbon Dioxide Capture Performance of KOH Aqueous Solution via Chemical Absorption (화학 흡수를 이용한 KOH 수용액의 이산화탄소 포집 성능에 관한 연구)

  • Yoo, Mi-Ran;Han, Sang-Jun;Shin, Ji-Yoon;Wee, Jung-Ho
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.1
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    • pp.55-62
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    • 2012
  • The present paper investigates the performance of the KOH aqueous solution as an absorbent to capture carbon dioxide ($CO_2$). The chemical absorption was carried out according to consecutive reactions that are generated in the order of $K_2CO_3$ and $KHCO_3$. The overall absorption was completed with following the physical absorption. When the absorption was conducted with the KOH as the limiting reactants in batch a reactor, $K_2CO_3$ production rate was the 1st order reaction for $OH^-$. However, $KHCO_3$ generation reaction was independent of the $CO_3^{2-}$ concentration and the rate was calculated to be $0.18gCO_2/min$ for all KOH absorbents, which is the same value of the reaction rate using $K_2CO_3$ aqueous solution as the absorbents. The overall $CO_2$ capture ratio of the 5% KOH absorbent was estimated to be 19% and the individual value in section 1 and 2 was 57 and 12%, respectively. The amount of $CO_2$ absorbed in the solution was very slightly less than the theoretical value, which was ascribed to the side reaction that produces $K_2CO_3{\cdot}KHCO_3{\cdot}1.5H_2O$ during the reaction and the consequent diminish in $CO_2$ absorption in the KOH solution.

A study on the renewal design development of marketing strategy (마케팅 전략에 따른 리뉴얼 디자인 전개에 관한 연구)

  • 신홍재;함재룡
    • Archives of design research
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    • no.16
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    • pp.1-14
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    • 1996
  • As the marketing strategy of corporations has been changing in various ways, the type of new product development has also bC'en changing in dim~rent ways. The types of changes include, among oiller things, product development. wit.h a new concept., revolut.ionary product development., new brand product. development., improvement. of existing product. and development. in model changes. The design development has similarly advanced with the growth in scient.ific approach in t11e design process of new product. development. in relat.ion t.o each t.ype of product development.. Ilowever, in view of the design approach or st.rat.egy for each t.ype, different. kinds of method of development is necessary. In order to increase t.he life cycle of an existing product. which has reached its mature stage and to respond t.o the changes 111 time t.hrough product improvement., it is becoming more imtxJrl.ant for Ule corporation to confonn wiU1 the changes in time by being able to sat.isfy the consumer! s needs, way of thinking and luxury inclination by utilizing the changes in design. However, it is very difficult to decide on a design using different development. methods which would clearly meet such neL'

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Biomass Estimation of Phyllostachys pubescens Stands in KFRI, Southern Forest Research Center (맹종죽 시험림의 현존량 추정에 관한 연구)

  • Lee, Kwang Soo;Jung, Su Young;Son, Yeong Mo;Lee, Kyeong Hak;Bae, Eun Ji;Yun, Seok Lak
    • Journal of Korean Society of Forest Science
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    • v.101 no.1
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    • pp.138-147
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    • 2012
  • For biomass estimation of Phyllostachys pubescens stands by optimal survey method we established 9 bamboo sample plots in the research forests of KFRI (Korea Forest Research Institute). The dry weight of culm segment determined by relative heights of total bamboo height show us two groups of 1st to 5th culm segment (up to 0~55% culm of tree height from the bottom area) and 6th to 8th culm segment (55~100%) by the results of cluster analysis for dry weight ratio. This results show that upper and lower part of 55~70% reference height from the bottom area against total culm height can be used in obtaining 1 kg of a sample bamboo, respectively, rather than 2.0 m stem segments of other forest tree species. In above-ground biomass estimation by $W=aD+bD^2$ having the highest coefficient of determination in this study, above ground stand biomass was 57.77 ton/ha (culm 40.47 ton/ha, branch 9.29 ton/ha, and leaf 8.01 ton/ha) of which 70% was contributed by culm component followed by branch (16%) and leaf (14%). Below-ground biomass was 53.35 ton/ha in total.

Coagulase Thping and Antibiotic Resistance of Methicillin Resistant Staphylococcus aureus (MRSA) Isolated form Patients in Pusan (부산지역 환자로부터 분리된 Methicillin Resistant Staphylococcus aureus(MRSA)의 응고효소형 및 항균제 내성에 관한 연구)

  • 류지한;이훈구
    • Korean Journal of Microbiology
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    • v.36 no.3
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    • pp.216-220
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    • 2000
  • Eighty-eight strain3 o~methicillin resistant Stopllylococcus awecis were Isolated from pus (64.7%); spuhm (26.2%), blood, fluid, andurine of 83 patients at Dong-A Hospital in P~~san to invesligate theil-coagulase typ- Ing, and multi-drug resistaut ppattems. The presence of niec A gene confe~~ing melhicillin resistance was tested by polymerase chain reaction (PCR) with uwo mec A gene specific primers using purified clromosonlal DNA as templates. DNA fragments of expected size wel-e detected frorn 86 strains, but not from two strains. !i coagulase typmg, the 86 isolates were assigned to 5 coagulase lypes, I, 11, lll. 1V, VI, VII, VIlI, but there was no isolate helong lo type V. The most abundant coagulase type was type TI(50 %), lollowed by type IV Rest ofthe coagulase types were ininor; ranging fmm 4.5 to 12.5 '% Most of the type I1 ~netlucillin resistant Stapl\ulcorneryiococcus nwem (MRSA) strams were isolated from the generd sulzely ward, but major strains of type IV were Isolated from the otorhinolq~ngology of the hospital's outpatient clinic center. All of the 88 st~nins were sensitive to vancomycin and teicoplanin, but 71 (81%) strains showed multi-drug resitant to penicillin, cephalotl~n, eiythroinycin, gentan~ycin, imipenem, clindamycin, ciprofloxacin and ooxacillin. Yo relationship was found between the antibiotic resistance pattems aud the coagulase typing patterns.

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Eine verfassungsrechtliche Rechtfertigungspr$\ddot{u}$fung von der Preisbekanntmachung der Individuellen Gesundheitsleistung (비급여진료비용 공개에 관한 헌법적 정당성 고찰)

  • Jung, Young-Chul
    • The Korean Society of Law and Medicine
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    • v.13 no.1
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    • pp.331-357
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    • 2012
  • Obwohl die Preisbekanntmachung der individuellen Gesundheitsleistung(PiG), die im Jahr 2010 im Arztrecht neu eingef$\ddot{u}$hrt wird, zum Management der Gesundheitskosten sehr n$\ddot{u}$tzig werden soll, muss eine verfassungsrechtliche Rechtfertigungspr$\ddot{u}$fung von PiG zun$\ddot{a}$chst durchgef$\ddot{u}$hrt werden. Angesichts der staatlichen Regulierung und Lenkung auf die Wirtschaft des Art. 119 Abs. 2 KV besitzt die PiG zun$\ddot{a}$chst eine Verfassungsrechtfertigung. Nach der st$\ddot{a}$ndigen Rechtsprechung des koreanischen Verfassungsgerichts folgt das Selbstbestimmungsrecht der Verbraucher aus der Menschenw$\ddot{u}$rde von Art. 10 Abs. 1 Koreanische Verfassung(KV) und dem Recht auf Gl$\ddot{u}$ck von Art. 10 Abs. 2 KV. Demnach k$\ddot{o}$nnen Konsumenten den Einkauf der G$\ddot{u}$ter und Service, die Partei des Vertrags, Gesch$\ddot{a}$ftsbedingungen, usw. frei entscheiden. Indem der Preis der individuellen Gesundheitsleistung mithin bekanntgemacht wird, werden das Selbstbestimmungsrecht der Verbraucher sowie das Recht der Konsumenten sicherlich gew$\ddot{a}$hrleistet. Dar$\ddot{u}$ber hinaus steht die PiG im Einklang mit dem Recht auf Information, aber auch z$\ddot{a}$hlt sie nicht zu den Informationen der Nichtbekanntmachung vom Gesetz $\ddot{u}$ber die Bekanntmachung der Information(GBI). Nach der staatlichen Gesundheitspflicht des Art. 36 Abs. 3 KV kann die PiG eine Verfassungslegitim$\ddot{a}$t besitzen. Im Hinblick auf die Berufsfreiheit kann die PiG einen Eingriff in den Gesch$\ddot{a}$ftsaktivit$\ddot{a}$ten der Unternehmen bedeuten. Trotzdem ist die PiG als eine verfassungsrechtliche Legitimit$\ddot{a}$t zu qualifizieren. In der Konsequenz kann die PiG, die auf dem Selbstbestimmungsrecht, dem Recht auf Information, dem Gesundheitsrecht, der Regulierung und Lenkung auf die Wirtschaft von Art. 119 Abs. 2 KV, und dem Recht der Verbraucher beruht, als eine verfassungm${\ddot{a}}{\ss}$ige Politik gesch$\ddot{a}$tzt werden.

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Larval Gnathostoma spinigerum Detected in Asian Swamp Eels, Monopterus albus, Purchased from a Local Market in Yangon, Myanmar

  • Chai, Jong-Yil;Sohn, Woon-Mok;Na, Byoung-Kuk;Park, Jong-Bok;Jeoung, Hoo-Gn;Hoang, Eui-Hyug;Htoon, Thi Thi;Tin, Htay Htay
    • Parasites, Hosts and Diseases
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    • v.53 no.5
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    • pp.619-625
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    • 2015
  • The present study was performed to determine the infection status of swamp eels with Gnathostoma sp. larvae in Myanmar. We purchased total 37 Asian swamp eels, Monopterus albus, from a local market in Yangon in June and December 2013 and 2014. All collected eels were transferred with ice to our laboratory and each of them was examined by the artificial digestion technique. A total of 401 larval gnathostomes (1-96 larvae/eel) were detected in 33 (89.2%) swamp eels. Most of the larvae (n=383; 95.5%) were found in the muscle. The remaining 18 larvae were detected in the viscera. The advanced third-stage larvae ($AdL_3$) were 2.3-4.4 mm long and 0.25-0.425 mm wide. The characteristic head bulb ($0.093{\times}0.221mm$ in average size) with 4 rows of hooklets, muscular long esophagus (1.025 mm), and 2 pairs of cervical sacs (0.574 mm) were observed by light microscopy. The average number of hooklets in the 1st, 2nd, 3rd, and 4th rows was 41, 45, 48, and 51, respectively. As scanning electron microscopic findings, the characteristic 4-5 rows of hooklets on the head bulb, a cervical papilla, tegumental spines regularly arranged in the transverse striations, and an anus were well observed. Based on these morphological characters, they were identified as the AdL3 of Gnathostoma spinigerum. By the present study, it has been confirmed for the first time that Asian swamp eels, M. albus, from Yangon, Myanmar are heavily infected with G. spinigerum larvae.

Effect of Scoria, Quartz Porphyry and Oak Charcoal Powder Feeding on the Meat Quantity and Quality of Fattening Cross Bred Hanwoo Bulls (점토광물 급여가 한우교잡우의 산육능력 및 육질에 미치는 영향)

  • 강수원;손용석;박남건;진신흠;고서봉
    • Journal of Animal Environmental Science
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    • v.5 no.3
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    • pp.157-170
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    • 1999
  • This study was conducted to investigate the effects of Scoria, Quartz porphyry and Oak charcoal powder feeding by 1% level of concentrate on the fattening cross bred bulls(5/8 Korean Native Cattle, 2/8 Charolais, 1/8 Brahman germ plasma) Feeding trial was conducted with 4 treatment groups which were T1(Full feeding of concentrate and roughage for 12 months), T2(T1 and Scoria addition), T3(T1 and Quartz porphyry addition) and T4(Oak charcoal addition) for 360 days, consisting of 32 heads whose initially weights were about 299.7kg. The results obtained are summarized as follows; 1. During the over-all period, average daily gains by T3, T4, T2 and T1 were 1.024, 0.987, 0.977kg and 0.964, respectively, without a significant difference by treatments. 2. Concentrate intakes per body weight and TDN intakes required per unit of kilogram gain were lower in addition agent groups than in control, and in all the treatments feed efficiency was higher at early stage for 360 fattening day than at end stage. 3. Carcass weight, dressing percent, back-fat thickness and loin eye muscle area by treatments were 330.9 to 348.4kg(average 340.3kg), 55.2~56.2(average 55.8%), 0.41~0.55(average 0.46cm)and 76.0~80.9$\textrm{cm}^2$(average 77.6$\textrm{cm}^2$), respectively, and were improved in addition agent groups than in control. 4. Meat quality grade is higher in addition agent groups than in control, and heads of 1st grade by treatments was 3, 2, 1 and none in T4, T2, T3 and T1, respectively. 5. Incidence heads of diseases by treatment were not apparently different, but diseases of digestive system was decreased in addition agent groups than in control. 6. The nitrate nitrogen content of fattening bull dung which collected in rectum were 0.082~0.089% (average 0.084%), and the content in addition agent groups was smaller than in controll. 7. Income was higher in order of T4, T3, T2, and T1 and incomes of treatment groups were grater than that of control group by 21.4 to 33.5 percent. According to the above results it may be concluded that fattening bulls may be required to feed no more than 1% of Scoria, Quartz porphyry and Oak charcoal powder based on the concentrate feeding level during the fattening period(12 to 24 month of age) to produce high quality meat and increase income.