• Korean Journal of Microbiology
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• v.44 no.2
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• pp.122-129
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• 2008

The purpose of this work was to investigate the synergically bactericidal effects and cellular responses of green tea polyphenols (TPPs) and nalidixic acid (NA) on nalidixic acid-resistant (NAR) Salmonella typhimurium. The bactericidal activities of $>3,500{\mu}g/ml$ TPPs and $<256{\mu}g/ml$ NA were investigated for S. typhimurium of which initial cell number was approximately adjusted to 107 cell/ml. Complete elimination of NAS-S. typhimurium was achieved within 6 hr of incubation at the concentrations of $3,500{\mu}g/ml$ TPP or $256{\mu}g/ml$ NA, whereas only partial bactericidal effect was achieved under the same conditions. However, the combinations of $3,000{\mu}g/ml$ TPPs and $32{\mu}g/ml$ NA against NAS-S. typhimurium and $3,500{\mu}g/ml$ TPPs and $64{\mu}g/ml$ nalidixic acid against NAR-S. typhimurium showed complete removal within 5 hr of incubation. The stress shock proteins (SSPs) were induced at different concentrations of TPP o rNA used as stressors against cell culture of S. typhimurium. The proteins were identified as 70-kDa DnaK and 60-kDa GroEL by SDS-PAGE and Western blot. SSPs induced by the stressors were found to increase in proportion to the TPPs or NA. Scanning electron microscopy analyses revealed the presence of perforations and irregular rod shape with wrinkled surfaces for cells treated with TPPs or NA.

• Microbiology and Biotechnology Letters
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• v.38 no.2
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• pp.198-206
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• 2010

The aim of this work was to investigate the synergically bactericidal effects and cellular responses of tea polyphenols (TPP) and imipenem on imipenem-resistant Pseudomonas aeruginosa. Imipenem-resistant Ps. aeruginosa was isolated from patient in hospital. The bactericidal effects of TPP and imipenem were evaluated on the basis of its minimum inhibitory concentrations (MIC). The combined use of TPP and imipenem resulted in 16-fold and 8-fold reductions in the MICs of imipenem for the imipenem-susceptible and imipenem-resistant Ps. aeruginosa, respectively. The bactericidal effects of the imipenem and TPP against the Ps. aeruginosa was evaluated using the time-kill assay. The synergetic effects of the combinations of TPP and imipenem against Ps. aeruginosa were confirmed. Western blot using anti-DnaK and anti-GroEL monoclonal antibodies was performed to investigate the expression of stress shock proteins (SSPs) in imipenem-susceptible and imipenem-resistant strains exposed to TPP. The amount of SSPs were induced as the exposure time increased and decreased. The molecular weights of DnaK and GroEL were 70 kDa and 60 kDa, respectively. SDS-PAGE with silver staining revealed that the amount of lipopolysaccharides (LPS) increased or decreased in the strain treated to different concentrations and exposing periods of TPP. Scanning electron microscopic analysis demonstrated the presence of umblicated and wrinkled surfaces for cells treated with TPP or imipenem.

• Ecology and Resilient Infrastructure
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• v.8 no.3
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• pp.154-163
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• 2021

This study was carried out to identify the factors affecting the distribution of suitable habitats for Geranium carolinianum, which was naturalized in South Korea, and to predict the changes of distribution in the future. We collected occurrence data of G. carolinianum at 68 sites in South Korea, and applied the MaxEnt model under climate change scenarios (SSP2-4.5, and SSP5-8.5). Precipitation seasonality (bio15), mean temperature of warmest quarter (bio10), and mean temperature of driest quarter (bio09) had high contribution for potential distribution of G. carolinianum. According to climate change scenarios, high suitable habitats of G. carolinianum occupied 6.43% of the land of South Korea in historical period (1981~2010), and 92.60% under SSP2-4.5, and 98.36% undr SSP5-8.5 in far future (2071~2100).

• Architectural research
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• v.12 no.2
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• pp.31-40
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• 2010

The main objective of this study is to investigate the perception, recognition and response of innovative/ self-initiated play and its correlation to play space and play environment understood by children in their middle childhood years. Play, play theory, and the acceptance of play have an important role in child development. In recent years, play and the importance of innovative/ self-initiated play have been associated with a number of important societal issues. The impact of play and/or lack of play during the developmental stages of childhood directly influence a child's ability to mature and adapt into society. In order to investigate the overall perceptions of play and play space among the average child in their middle childhood, a questionnaire survey was distributed and analyzed using SSPS 15.0. This survey was conducted within the site specific context of South Korea. Interestingly enough, the differences in the responses can be organized into three main categories: age, gender and housing type. In result different directions for further study and research for future play spaces and play environments that support innovated/ self-initiated play have been suggested.

• Journal of Microbiology and Biotechnology
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• v.14 no.3
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• pp.628-630
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• 2004

Antitumor activities of a peptide fraction isolated from traditional Korean soy sauce (SSP) were investigated in vitro and in vivo using cancer cell lines and F9 teratocarcinoma-bearing BALB/c mice. SSP exerted a dose-dependent antiproliferative effect on P388D1 mouse lymphoma, F9 mouse teratocarcinoma, and DLD-l human colon cancer cells with $IC_{50}$ values of 11, 50, and $50\mug/ml$, respectively. Tumor growth in F9 teratocarcinoma-bearing BALB/c mice, orally administered with 80 and 200 mg/kg/day of SSPs, was inhibited 10.3% and 52.4%, respectively, and survival days increased by 11.9% and 22.1%, respectively, compared to the control group. The results of antitumor activities exerted by SSP in vitro and in vivo suggest the feasibility of using SSP as an antitumor agent.

• Korean Journal of Adult Nursing
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• v.18 no.3
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• pp.479-487
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• 2006

Purpose: The purposes of this study were to measure the degree of uncertainty in illness, hope, and spiritual well-being and to examine the relationship among uncertainty in illness, hope, and spiritual well-being of cancer patients. Method: The data were derived from answers to questionnaires obtained from 93 cancer patients at one general hospital in J area from April 6, 2004 to May 8, 2004. The collected data were analyzed by SSPS 10.0. Results: The mean score of uncertainty in illness of cancer patients was 55.96. The mean score of hope of cancer patients was 79.77, and spiritual well-being was 55.20. Uncertainty in illness of cancer patients was related negatively to hope(r=-.57, p=.000). Also uncertainty in illness of cancer patients was related negatively to spiritual well-being(r=-.57, p=.000). However, hope of cancer patients was related positively to spiritual well-being(r=.67, p=.000). Conclusion: Higher uncertainty in illness was related to lower hope and spiritual well-being of cancer patients. Based upon these results, nurses should help patients to improve their hope and spiritual well-being through mediation of uncertainty in illness.

• Journal of Communications and Networks
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• v.8 no.3
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• pp.267-274
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• 2006

Self-spreading (SSP) is a spread spectrum technique where the spreading sequence is generated from data bits. Although SSP allows communications with low probability of interception by unintended receivers, despreading by the intended receiver is prone to error propagation. In this paper, we propose both a new transmitter and a new receiver based on SSP with the aim to a) reduce error propagation and b) increase the concealment of the transmission. We first describe a new technique for the generation of SSP spreading sequence, which generalizes SSPs of existing literature. We include also coding at the transmitter, in order to further reduce the effects of error propagation at the receiver. For the receiver, we propose a turbo architecture based on the exchange of information between a soft despreader and a soft-input soft-output decoder. We design the despreader in order to fully exploit the information provided by the decoder. Lastly, we propose a chip decoder that extracts the information on data bits contained in the spreading sequence from the received signal. The performance of the proposed scheme is evaluated and compared with existing spread-spectrum systems.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.172-172
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• 2018

물이용의 기후변화 취약성은 기후변화 뿐 아니라 이의 직, 간접적 영향으로 인한 물수요량 변화 등의 다양한 요소에 의한 영향을 받기 때문에 그 정도를 파악하기가 어렵다. 또한 기존의 대부분의 물이용 취약성 평가 연구는 단순 기후요소의 변화만 고려한 경우가 대부분이고 사회경제적 요소의 변화를 반영하지 않았다는 한계가 있다. 따라서 본 연구에서는 강 유역에서 미래 기후 변화와 사회경제적 변화에 따른 물이용 취약성 평가방법을 개발하고, 한강에 적용함으로서 다양한 사회경제시나리오에 따른 강유역의 물이용 취약성이 어떠한 영향을 받는지에 대한 이해에 주안점을 맞췄다. 개발한 평가방법은 지표기반 접근법으로, 다기준 의사결정기법인 Technique for Order of Preference by Similarity to Ideal Solution(TOPSIS)를 사용하였다. 이 방법은 IPCC의 취약성분석 방법에 사용되고 있으며, 취약성에 대한 정의에 따라 결과 값이 적응능력, 노출, 민감도로 구성되어있다. 사용된 지표 자료는 통계청 등 다양한 국가 통계자료를 기반으로 한 자료뿐 아니라, 일부분은 수문모형인 SWAT(Soil and Water Assessment Tool)모델로부터 모의된 결과를 포함한다. 기후시나리오로 Representative Concentration Pathways(RCPs), 사회경제시나리오로는 Shared Socioeconomic Pathways(SSPs)를 사용하였다. 본 연구의 물이용 취약성 평가결과는 사회경제적 요소의 변화를 기존의 평가방법에 추가 반영하여 미래 전망을 제시하는 향후 수자원 정책 방향에 기초자료로 활용될 수 있을 것이다.

• Atmosphere
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• v.33 no.5
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• pp.505-517
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• 2023

This study investigates the impacts of carbon neutrality and air quality control policies on near-term climate change in East Asia, by examining three Shared Socioeconomic Pathways (SSPs) scenarios from five climate models. Specifically, low carbon and strong air quality control scenario (SSP1-1.9), high carbon and weak air quality control scenario (SSP3-7.0), and high carbon and strong air quality control scenario (SSP3-7.0-lowNTCF) are compared. For these scenarios, the near-term climate (2045-2054 average) changes are evaluated for surface air temperature (SAT), hot temperature extreme intensity (TXx), and hot temperature extreme frequency (TX90p). In all three scenarios, SAT, TXx, and TX90p are projected to increase in East Asia, while carbon neutrality reduces the increasing rate of SAT and hot temperature extremes. Air quality control strengthens the warming rate. These opposed mitigation effects are robustly forced in all model simulations. Nonetheless, the impact of carbon neutrality overcomes the impact of air quality control. These results suggest that fast carbon neutrality, more effective than an air quality control policy, is necessary to slowdown future warming trend in East Asia.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1879-1883
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• 2014

Background: The relationship between obesity and prostate cancer aggressiveness is controversial in recent studies, partly because BMI is the only generally applied marker of obesity. Our study aimed at evaluating the correlation of periprostatic fat (PF) on magnatic resonance imaging (MRI) and adipocytokines with prostate cancer aggressiveness. Patients and method: A total of 184 patients who underwent radical retropubic prostatectomy (RRP) were analyzed retrospectively; different fat measurements on MRI slices and levels of adipocytokines were compared with the clinical and pathologic factors using SSPS ver.13.0. Result: The PF rates showed a statistically significant variation (p=0.019, 0.025) among groups, that is to say, more adipose tissue was distributed in periprostatic areas of high risk patients. Logistic regression analysis adjusted for age revealed a statistically association between the PF, the ratio and the risk of having high-risk disease (p=0.031, 0.024). The levels of IL-6, leptin and c-reactive protein (CRP) significantly increased with the aggressiveness of prostate cancer, and also with PF and its ratio. The strongest correlation was seen between IL-6 and PF (Pearson r coefficient=0.67, P<0.001). No association was observed between adipocytokines and BMI. Conclusion: Periprostatic adiposity not only affects prostate cancer aggressiveness, but also influences the secretion of adipocytokines. IL-6, PF and CRP have promoting effects on progression of prostate cancer.