• 제목/요약/키워드: SSE

검색결과 327건 처리시간 0.027초

홍화인 추출물이 골 형성에 미치는 영향에 관한 실험실적 연구 (A Study of Safflower Seed Extracts on Bone Formation in Vitro)

  • 이성진;최호철;선기종;송제봉;피성희;유형근;신형식
    • Journal of Periodontal and Implant Science
    • /
    • 제35권2호
    • /
    • pp.461-474
    • /
    • 2005
  • The ultimate goal of periodontal therapy is the regeneration of periodontal tissue and the repair of function. For more than a decade there have been many efforts to develop materials and methods of treatment to promote periodontal tissue regeneration. Recently many efforts are concentrated on the regeneration potential of material used in traditional medicine. Safflower(Carthamus tinctorius L.) seed extract(SSE) have long clinically used in Korea to promote bone formation and prevent osteoporosis. The purpose of this study was to examine the effects of SSE on bone formation in human osteoblastic cell line. Human fetal osteoblastic cell line(hFOB 1.19) was cultured with DMEM and SSE($1{\mu}g/ml$, $10{\mu}g/ml$, $100{\mu}g/ml$, $1mg/ml$) at $34^{\cdot}C$ with 5% $CO_2$ in 100% humidity. The proliferation, differentiation of the cell was evaluated by several experiments. Cell proliferation was significantly increased at $10{\mu}g/ml$, $100{\mu}g/ml$, 1mg/ml of SSE after 3 and 7 days incubation(p<0.05). Cell spreading assay was significantly increased at $100{\mu}g/ml$ of SSE after 3 days and $1{\mu}g/ml$, $10{\mu}g/ml$, $100{\mu}g/ml$, 1mg/ml of SSE after 7 days(p<0.05). Alkaline Phosphatase(ALP) level was significantly increased in $10{\mu}g/ml$, $100{\mu}g/ml$, 1mg/ml of SSE(p<0.05). Collagen synthesis was significantly increased at $10{\mu}g/ml$, $100{\mu}g/ml$, 1mg/ml of SSE(p<0.05). A quantified calcium accumulation was significantly increased at $10{\mu}g/ml$, $100{\mu}g/ml$ of SSE(p<0.05). ALP and osteocalcin mRNA was expressed in $100{\mu}g/ml$ of SSE by RT-PCR. These results indicate that SSE are capable of increasing osteoblasts mineralization and may play an important role in bone formation.

Hydroalcoholic Extract of Scrophularia Striata Attenuates Hypertrophic Scar, Suppresses Collagen Synthesis, and Stimulates MMP2 and 9 Gene Expression in Rabbit Ear Model

  • Zarei, Hatam;Tamri, Pari;Asl, Sara Soleimani;Soleimani, Meysam;Moradkhani, Shirin
    • 대한약침학회지
    • /
    • 제25권3호
    • /
    • pp.258-267
    • /
    • 2022
  • Objectives: Hypertrophic scars (HSs) are caused by abnormal wound healing. To date, no standard treatment has been made available for HSs. Scrophularia striata has been reported to accelerate wound healing and has the potential to prevent HS formation. In this study, we investigated the anti-scarring effects of S. striata extract (SSE) in a rabbit ear model of scarring. Methods: In this study, New Zealand white rabbit (weight: 2.3-2.5 kg) were used. In the prevention phase of the study, three test groups received 5%, 10%, and 15% ointments of SSE in the Eucerin base, the fourth group received Eucerin, and the fifth group received no treatment. The samples were obtained on day 35 after wounding. In the treatment phase of the study, the test groups received an intralesional injection of SSE (5%, 10%, and 15%), the fourth group received an intralesional injection of triamcinolone, the fifth group received a solvent (injection vehicle), and the sixth group received no treatment. To evaluate the anti-scarring effects of SSE, the scar elevation index (SEI), epidermis thickness index (ETI), collagen deposition, and MMP2 and MMP9 gene expression were evaluated. Results: A significant reduction in SEI, ETI, and collagen deposition was noted in animals treated with SSE compared with the control groups. In addition, topical SSE stimulated MMP2 and MMP9 gene expression. Conclusion: The findings of this study demonstrate the potential for SSE in the prevention and treatment of HS. SSE could be prepared as an appropriate formulation to treat wounds and prevent abnormal scarring.

A Study on ZnSSe : Te/ZnMgSSe DH Structure Blue and Green Light Emitting Diodes

  • Lee Hong-Chan
    • Journal of Advanced Marine Engineering and Technology
    • /
    • 제29권7호
    • /
    • pp.795-800
    • /
    • 2005
  • The optical properties of $ZnS_{y}Se_{1-x-y}:Te_x\;(x\;<\;0.08,\;y\∼0.11$) alloys grown by molecular beam epitaxy (MBE) have been investigated by photoluminescence (PL) and PL-excitation (PLE) spectroscopy. Good optical properties and high crystal quality were established with lattice match condition to GaAs substrate. At room temperature, emission in the visible spectrum region from blue to green was obtained by varying the Te content of the ZnSSe:Te alloy. The efficient blue and green emission were assigned to $Te_{1}$Tel and $Te_{n}$ (n$\geq$2) cluster bound excitons, respectively. Bright blue (462 nm) and green (535 nm) light emitting diodes (LEDs) have been developed using ZnSSe:Te system as an active layer.

ZnSSe:Te계 청 -녹색 발광다이오드의 고효율화 및 장수명화에 관한 연구 (Study of High-efficiency and Long-lived Blue - Green Light Emitting Diodes Using ZnSSe:Te System Grown by MBE)

  • 이홍찬;이상태;이성근;김윤식
    • 한국마린엔지니어링학회:학술대회논문집
    • /
    • 한국마린엔지니어링학회 2002년도 춘계학술대회논문집
    • /
    • pp.167-171
    • /
    • 2002
  • We have investigated the optical properties of Te-doped ZnSSe:Te epitaxial layers grown on (100) GaAs substrates by molecular beam epitaxy. The Te-doped ternary specimen shows strong blue or green emission (at 300k) which is assigned to Te$_{1}$ or Te$_{n}$( n$\geq$2) cluster bound exciton. Bright green and blue light-emitting diodes (LEDs) have been developed using ZnSSe:Te system as an active layer. The green LEDs exhibit a fairly long device lifetime (>2000 h) when operated at 3 A/cm$^{2}$ under CW condition at room temperature. It is confirmed that the Te-doping induced "crystal-hardening effect" plays a significant role in both efficient and strong suppression of the optical device degradation.gradation.

  • PDF

삼소음(蔘蘇飮)이 천식이 유발된 생쥐의 cytokine 분비에 미치는 영향 (Effects of Samso-Eum on cytokine productions in asthmatic mice)

  • 김형우;조수진;김부여;백진웅;정현우;조수인
    • 대한본초학회지
    • /
    • 제22권2호
    • /
    • pp.175-180
    • /
    • 2007
  • Objective : The application of Sam So Eum (蔘蘇飮, SSE) as a herbal medicine to treat asthma in mice has been studied and the mechanism of cytokine production in asthmatic mice was discussed. Recently, SSE was known to have anti-allergic activity. However, its therapeutic mechanisms are unclear. Methods : So, we investigated the effects of SSE on levels of several cytokines in bronchoalveolar lavage fluid (BALF) using flow cytometric analysis in allergen-induced asthma. Results : In this experiment, SSE decreased levels of IL-la, IL-17 and GM-CSF respectively. Contrary, SSE restored level of IFN-g toward naive level in BALF. Conclusion : In conclusion, we demonstrate that SSE is useful to treat asthma and it's therapeutic mechanisms are involved in Thl skewing reaction.

  • PDF

Effects of Cervical Stabilization and Scapular Stabilization Exercise on the Proprioception and Craniovertebral Angle and Upper Trapezius Muscle Tone of People with F orward Head Posture

  • Seung-Hwan, Lee;Byoung-Ha, Yoo;Hyun-Seo, Pyo;Dongyeop, Lee;Ji-Heon, Hong;Jae-Ho, Yu;Jin-Seop, Kim;Seong-Gil, Kim
    • 대한물리의학회지
    • /
    • 제17권4호
    • /
    • pp.1-13
    • /
    • 2022
  • PURPOSE: This study examined the effects of the craniovertebral angle, proprioception (joint error test), and the upper trapezius on the muscle tone when comparing cervical stabilization and scapula stabilization exercises and when two exercises were performed together. METHODS: The participants in this study agreed in advance, and this study was carried out by recruiting 27 university students in their twenties with mild frontal posture. The subjects were assigned randomly to three groups that performed cervical stabilization exercises, scapular stabilization exercises, and both cervical and scapular stabilization exercises. One-way repeated ANOVA was used to analyze the evaluation values of the 1st, 3rd, and 6th weeks of exercise intervention within the group, and one-way ANOVA was used to compare the difference in the effects of exercise intervention among the three groups. RESULTS: Proprioception was significantly different in the cervical stabilization exercises (CSE) group and the cervical stabilization exercises + Scapular stabilization exercises (CSE+SSE) groups at three weeks, and there was a significant difference between the scapular stabilization exercises (SSE) group and the CSE+SSE group (p < .05). At six weeks, there was a significant difference between the CSE group and the CSE+SSE group, and there was a significant difference between the SSE group and the CSE+SSE group (p < .05). There was a significant difference between three and six weeks in the CSE group (p < .05). In the SSE group, there was a significant difference between pre and six weeks, and between three and six weeks (p < .05). In the CSE+SSE group, there was a significant difference between pre and three weeks, and between pre and six weeks (p < .05). On the other hand, there were no significant differences between CVA and muscular tone in all three groups (P > .05). CONCLUSION: In all groups, the proprioception (joint error test) showed significant improvement, and the CSE+SSE group showed greater improvement than the other groups. As a result, the appropriate combination of neck stabilization exercise and scapular stabilization exercise effectively improved proprioception in the presence of forward head posture (FHP).

Solar Energy Conversion by the Regular Array of TiO2 Nanotubes Anchored with ZnS/CdSSe/CdS Quantum Dots Formed by Sequential Ionic Bath Deposition

  • Park, Soojeong;Seo, Yeonju;Kim, Myung Soo;Lee, Seonghoon
    • Bulletin of the Korean Chemical Society
    • /
    • 제34권3호
    • /
    • pp.856-862
    • /
    • 2013
  • The photoanode electrode of $TiO_2$ nanotubes (NTs) anchored with ZnS/CdSSe/CdS quantum dots (QDs) was prepared by anodization of Ti metal and successive ionic layer adsorption and reaction (SILAR) procedure. The tuning of the band gap of CdSSe was done with controlled composition of Cd, S, or Se during the SILAR. A ladder-like energy structure suitable for carrier transfer was attained with the photoanode electrode. The power conversion efficiency (PCE) of our solar cell fabricated with the regular array of $TiO_2$ NTs anchored with CdSSe/CdS or CdSe/CdS QDs [i.e., (CdSSe/CdS/$TiO_2NTs$) or (CdSe/CdS/$TiO_2NTs$)] was PCE = 3.49% and 2.81% under the illumination at 100 mW/$cm^2$, respectively. To protect the photocorrosion of our solar cell from the electrolyte and to suppress carrier recombination, ZnS was introduced onto CdSSe/CdS. The PCE of our solar cell with the structure of a photoanode electrode, (ZnS/CdSSe/CdS/$TiO_2$ NTs/Ti) was 4.67% under illumination at 100 mW/$cm^2$.

MBE로 성장시킨 3원계 ZnSSe/GaAs 에피층의 미세구조 특성 (Microstructure Characterization of Ternary ZnSSe/GaAs Epilayer Grown by MBE)

  • 이확주;류현;박해성;김태일
    • Applied Microscopy
    • /
    • 제25권3호
    • /
    • pp.75-81
    • /
    • 1995
  • 이상과 같은 실험에서 다음과 같은 사실을 요약할 수 있다. 1) ZnSSe/GaAs 에피층에는 많은 양의 적층결함과 전위 등의 결정결함이 존재하고 이들은 표면부 보다는 계면부에 더 많이 존재한다. 그러나 에피층은 기판과 pseudomorphic 성장을 이루고 있다. 2) ZnSSe/GaAs 계면에는 5nm 크기의 높이차가 나는 굴곡이 존재하며 ZnSe 버퍼 층에 관계없이 적층결함이 존재하고, 에피층 결정이 약간 기울어져서 므와레 줄무늬 패턴도 존재한다. 3) ZnSSe/GaAs 계면에는 성장 중에 S의 침투로 인한 <111>방향으로 피트가 형성되었음이 관찰되었고 이는 결함 생성 소스로 작용한다 4) 15nm 높이차가 나는 계면이 발견되었으나 기판과 정합을 이루고 있고 주변에는 적층결함도 존재하지 않는다. 그러나 미세한 므와레 줄무의형태가 존재하였다.

  • PDF

영역기반 스테레오 영상 정합을 위한 고속 SAD 알고리즘 (A Fast SAD Algorithm for Area-based Stereo Matching Methods)

  • 이우영;김정길
    • 한국위성정보통신학회논문지
    • /
    • 제7권2호
    • /
    • pp.8-12
    • /
    • 2012
  • 스테레오 비전 분야에서 영역 기반의 영상 정합은 스테레오 영상 분석을 위한 대표적인 방법이다. SAD (Sum of Absolute Difference) 알고리즘은 영역 기반 정합 알고리즘의 한 종류로서 대규모 데이터 집약적 계산을 요구하여 소프트웨어 방식을 사용할 경우 처리속도가 매우 느리게 된다. 본 논문에서는 소프트웨어 기반 SIMD (Single Instruction Multiple Data) 병렬 기법인 SSE (Streaming SIMD Extensions) 명령어를 이용한 고속 SAD 알고리즘을 제안한다. SSE 명령어를 지원하는 CPU는 16개의 128비트 크기의 XMM 레지스터를 보유하여 SIMD 명령어 집합 확장을 가능하게 하였다. 제안하는 소프트웨어 기반 병렬 고속화 기법의 성능 측정을 위하여 일반적 SAD를 이용한 영상 정합 알고리즘과 SSE 명령어를 사용한 알고리즘의 수행 속도차이를 측정하였다. 제안하는 기법은 일반적 SAD 알고리즘보다 평균 4배의 성능 향상의 결과를 보임으로 소프트웨어 기반 고속병렬 처리를 통한 실시간 스테레오 비전 응용분야에 효과적으로 적용될 수 있음을 보였다.

꽈배기 모자반 추출물 첨가에 의한 빵의 저장성 및 품질 증진 효과 (Effect of Extracts from Sargassum siliquastrum on Shelf-life and Quality of Bread)

  • 이소영;김꽃봉우리;송유진;김진희;김아람;김미정;문지혜;강희문;이호동;홍용기;안동현
    • 한국식품영양과학회지
    • /
    • 제37권4호
    • /
    • pp.490-496
    • /
    • 2008
  • 꽈배기 모자반 추출물을 0.01%, 0.1%, 1% 농도로 첨가하여 이들이 모닝빵의 저장성과 품질에 미치는 영향에 대하여 알아보았다. 9일간 저장하며 일반 세균수와 곰팡이수를 측정한 결과 저장기간 전반에 걸쳐 첨가 농도가 증가할수록 미생물의 생육이 억제되었으며, 수분함량의 변화에 있어서는 꽈배기 모자반 추출물 처리구가 약 $5{\sim}6%$ 정도의 변화를 보인 반면 무처리구는 13% 정도의 큰 변화 폭을 보였다. 색도의 경우에는 추출물의 첨가농도가 높을수록 명도와 황색도는 감소하는 경향을 나타내었으며, 적색도는 이와 반대로 첨가 농도에 의존하여 증가하는 것으로 나타났다. 관능평가에서는 전체적인 호감도에서 0.01%와 0.1% 첨가구가 무처리구에 비하여 높은 점수를 받았으나 1% 첨가구에서는 가장 낮은 점수를 받았다. 이상의 결과를 종합해 볼 때 꽈배기 모자반 추출물을 0.1%정도 첨가할 경우 빵의 저장성, 품질 증진 및 관능 개선 효과가 있을 것으로 사료된다.