• Title/Summary/Keyword: SOX-2

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Alk3/Alk3b and Smad5 Mediate BMP Signaling during Lymphatic Development in Zebrafish

  • Kim, Jun-Dae;Kim, Jongmin
    • Molecules and Cells
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    • v.37 no.3
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    • pp.270-274
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    • 2014
  • Lymphatic vessels are essential to regulate interstitial fluid homeostasis and diverse immune responses. A number of crucial factors, such as VEGFC, SOX18, PROX1, FOX2C, and GJC2, have been implicated in differentiation and/or maintenance of lymphatic endothelial cells (LECs). In humans, dysregulation of these genes is known to cause lymphedema, a debilitating condition which adversely impacts the quality of life of affected individuals. However, there are no currently available pharmacological treatments for lymphedema, necessitating identification of additional factors modulating lymphatic development and function which can be targeted for therapy. In this report, we investigate the function of genes associated with Bone Morphogenetic Protein (BMP) signaling in lymphatic development using zebrafish embryos. The knock-down of BMP type II receptors, Bmpr2a and Bmpr2b, and type I receptors, Alk3 and Alk3b, as well as SMAD5, an essential cellular mediator of BMP signaling, led to distinct lymphatic defects in developing zebrafish. Therefore, it appears that each constituent of the BMP signaling pathway may have a unique function during lymphatic development. Taken together, our data demonstrate that BMP signaling is essential for normal lymphatic vessel development in zebrafish.

Prediction of NOx emission for marine gas engines (선박용 가스엔진의 NOx 배출량예측에 관한 연구)

  • Jang, Ha-Seek;Lee, Ji-Woong;Lee, Kang-Ki;Choi, Jae-Sung
    • Journal of Advanced Marine Engineering and Technology
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    • v.38 no.6
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    • pp.658-665
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    • 2014
  • Natural gas for marine diesel engine is considered as an important and clean source of energy because of simultaneously reducing the emission of NOx, SOx and GHG. Especially with a appearance of shale gas, the using of natural gas has been investigated aggressively and expected to expand rapidly. By the reports, gas engine and diesel engine were both in a similar performance in the power aspect, and the SFOC of gas engine was shown a little better than that of diesel engine. But the characteristics of exhaust gas emission were different according to various combustion technologies. And with lean burn technology, the emission of NOx could be reduced to 85% lower than that of diesel engine. In this paper, it was described that a simulation program has been developed to predict NOx emission. The developed program is adopted two-zone model and Wiebe function for combustion in cylinder. The effects of premixed and diffusive combustion could be simulated by using the excess air ratio as input data. And it was confirmed that the results of simulation were agreed with the general trends of exhaust gas emission according to various combustion conditions such as lean burn, premixed and diffusive combustion.

Wet Chemical Process for Improving Air Quality in Semiconductor Manufacturing Process (반도체 생산공정의 대기질 개선을 위한 복합 대기오염물의 습식화학 제거공정)

  • Jun, Chang-Sung;Kim, Hak-Ju;Park, Young-Moo;Lee, Dae-Won;Ham, Dong-Suk;Jeon, Sang-Moon;Lee, Kwan-Young
    • Clean Technology
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    • v.13 no.2
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    • pp.109-114
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    • 2007
  • In this study, we performed basic researches to develop wet purification system for improving air qualities of ventilation in semiconductor manufacturing process. Using 0.5 M aqueous solution of $KMnO_4$, 50 ppm of $NH_3$, SOx and NOx were reduced to 99% successfully. However, the removal of $O_3$ was limited to $22{\sim}30%$ for all the tested chemical solutionsincluding $KMnO_4$. Therefore, adoption of a dry ozone filter is necessary to reduce $O_3$ below a satisfactory level. For all the chemical solutions tested, NOx removal efficiency increased as NOx was mixed with $O_3$. As chemical solution was sprayed using water spraying system equipped with air atomizing type nozzle, the removal efficiencies of gaseous pollutants increased due to the increase of gas-liquid interfacial area.

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Synthesis and Characterization of Oxygen Evolution Nanofiber electrocatalyst for Water Electrolysis (수전해 산소발생을 위한 나노섬유 전기화학 촉매 합성 및 특성분석)

  • Won, Mi-So;Jang, Myeong-Je;Lee, Gyu-Hwan;Choe, Seung-Mok
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2016.11a
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    • pp.186-186
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    • 2016
  • 수소는 연료전지 등의 에너지원으로 사용될 경우 NOx, SOx, $CO_2$ 등의 한경오염물질, 온실가스를 발생시키지 않기 때문에 친환경 에너지원으로 각광을 받고 있다. 수전해는 수소를 생산하는 가장 간단하고 효율적인 방법 중의 하나로서, 잉여전력 또는 신재생에너지에 의한 전기에너지를 통해 환경오염물질 발생 없이 고순도의 수소를 얻을 수 있으며 분산/대량 생산이 용이하다. 수전해에서 환원전극에서는 수소발생반응이 일어나고, 산화전극에서는 산소발생반응이 일어난다. 이때 주로 산소발생전극 촉매로는 과전압이 작게 걸리고 활성이 우수한 귀금속 계열의 $IrO_2$$RuO_2$ 등의 촉매가 현재 사용되고 있다. 본 연구에서는 고분자 용액을 만들어 전기방사를 이용하여 공정변수에 따른 직경과 morphology를 확인하였고, 고가의 귀금속 산화물 대신 저렴한 전이금속산화물인 Cu와 Co를 이용하여 1D 나노섬유를 산소발생 촉매로 합성하였다. 합성된 나노섬유의 구조적, 물리화학적 특성을 분석하고 산소발생반응(OER)에 대한 전기화학적 활성 및 내구성을 평가하였다.

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Chemical Characteristics of Rainfall and Throughfall in Pinus koraiensis and Larix leptolepis Forests in Korea

  • Kim, Min-Sik;Takenaka, Chisato;Park, Ho-Taek;Chun, Kun-Woo
    • Journal of Korean Society of Forest Science
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    • v.94 no.2 s.159
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    • pp.96-102
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    • 2005
  • This study evaluated the chemical characteristics of rainfall and throughfall in Pinus koraiensis and Larix leptolepis forests. We analyzed pH, EC, and concentrations of cations and anions in rainfall, throughfall and stemflow collected from both forest types in the experimental forests of the central Korea. The concentrations of chemical elements were much higher in throughfall and stemflow than in rainfall for both forest types, and were significantly different among the seasons. Comparing the chemical elements between the P. koraiensis and L. leptolepis plantations, there were not significantly differences in throughfall, but the concentrations of almost elements of stemflow in P. koraiensis were almost lower than those in L. leptolepis. For seasonal inputs to the forest floor, more than half of the total input of $Ca^{2+}$, ${NO_3}^-$and ${SO_4}^{2-}$ was observed in spring. This suggests that air pollutants such as NOx and SOx accompanying calcium-rich aeolian Yellow Sand (Asian dust) from China could have an important influence on nutrient cycles in Korean forests.

자연계로부터 분리한 strain YJ에 의한 수소생산에 관한 연구

  • Lee, Gi-Seok;Gwak, Gyeong-O;Kim, Seong-Jun;Jeong, Seon-Yong
    • 한국생물공학회:학술대회논문집
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    • 2002.04a
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    • pp.407-410
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    • 2002
  • Hydrogen is considered to be a clean energy because it doesn't generate the global warming gas such as $CO_2$, SOx and NOx, after its combustion. In this study, strain YJ isolated from shore system was used to produce efficiently hydrogen using the various carbon sources such as glucose, sucrose and fructose and its characteristics were investigated in batch cultivation. The maximum hydrogen production shown that glucose, sucrose and fructose were highest obtained at 2, 4 and 5 % concentration, respectively. In addition, we investigated the effect of pH under various conditions as range of initial pH 5.5 to 8.0 pH because growth of strain YJ declined due to produced organic acids. The results showed that the highest production rate of hydrogen was obtained at pH 7.5.

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A Study on Operating Characteristics of the CO2 Laser with Inductively Pulsed Power System (유도형(誘導型) Pulsed Power 전원을 이용한 CO2 레이저 동작 특성에 관한 연구)

  • Kim, Geun-Yong;Min, Byoung-Dae;Kim, Yong-Cheol;Lee, Yu-Soo;Chung, Hyun-Ju;Kim, Hee-Je
    • Proceedings of the KIEE Conference
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    • 2002.07c
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    • pp.1710-1713
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    • 2002
  • Recently, the pulsed power system has been used to many applications. Such as remediation of environmental hazards, food sterilization, air pollution control E/P (Electrostatic Precipitator), DeNOx/DeSOx power system, ozone generator, high energy physics, and other power source applications. A pulse energy efficiency for load depends on the rising time, peak value. Pulse duration and impedance matching etc. The pulsed power system generally required for short pulse duration and high peak value was forced to consider its volume and economy. In this paper, we investigated operating characteristics of the CO2 laser using an inductively pulsed power system.

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Neuroprotective Effects of N-Acetyldopamine Dimers from Cicadidae Periostracum

  • Thapa, Punam;Katila, Nikita;Choi, Hyukjae;Han, Ah-Reum;Choi, Dong-Young;Nam, Joo-Won
    • Natural Product Sciences
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    • v.27 no.3
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    • pp.161-168
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    • 2021
  • The chemical investigation of the 90% EtOH extract from Cicadidae Periostracum led to the isolation and identification of seven known N-acetyldopamine dimers (1-7). These compounds were identified by comparing mass spectrometry data and NMR spectroscopic data with those previously reported. In this study, complete interpretation of 1D and 2D NMR data of 1 and 2 were reported for the first time. In addition, compounds 3 and 4 were isolated from this material for the first time. All isolates were obtained as racemic mixtures, as confirmed by chiral HPLC. Furthermore, we evaluated the neuroprotective activities of compounds 1-7 and found that compounds 1, 5, and 6 significantly attenuated rotenone-induced death of SH-SY5Y neuroblastoma cells at a concentration of 100 μM. Parallel to this result, compounds 3 and 6 displayed antioxidant effects in the cytoplasm, as determined by CM-H2DCFDA fluorescence intensity, while compounds 1 and 5 showed antioxidant effects in the mitochondria, as assessed by MitoSox fluorescence intensity. Overall, these results suggest that some of these compounds protect neuroblastoma cells by ameliorating the release of reactive oxygen species. Further studies are warranted to elucidate the underlying mechanisms by which these compounds exhibit antioxidant and neuroprotective actions.

A Study on the Measurement of SOx-Dew Point (About the Corosin of Briquet -Burning Hot Water Boiler) ($SO_x^-$ 노점 측정에 관한 연구 (연탄 온수보일러의 부식문제에 관하여))

  • Chae Jae-Ou;Yong Gee-Joong
    • The Magazine of the Society of Air-Conditioning and Refrigerating Engineers of Korea
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    • v.12 no.4
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    • pp.252-263
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    • 1983
  • In the briquet-burning hot water boiler the $SO_x$-dew point is calculated and found to be between $130^{\circ}C\;and\;154^{\circ}C$. The corrosion rate depends on the surface temperature and the concentration of the condensate on the surface. The concentration of the condensate is decided acoording to the difference detween $SO_x$-dew point and the surface temperature. When the surface temperature is $80^[\circ}C$, the concentration of the condensate is also high (0.15N). Therefore the high concentration and high temperature promote the high corrosion rate of $14{\times}13^{-3}g/100cm^2{\cdot}hr$ on the SS41 material. On the other hand, when the surface temperatures are $60^{\circ}C\;and\;40^{\circ}C$, the concentrations and the co..sion rates are reduced dramatically to $0.11\;N,\;8.6{\tiems}10^{-3}g/100cm^2{\cdot}hr$ and $5{\tiems}10^{-4}g/100cm^2{\cdot}hr$ respectively.

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A proposal on SOFC-PEMFC combined system for maritime applications

  • Duong Phan Anh;Ryu Borim;Nguyen Quoc Huy;Lee Jinuk;Kang Hokeun
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2022.11a
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    • pp.162-163
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    • 2022
  • Maritime transportation is going to transfer to alternative fuels as a result of the worldwide demands toward decarbonization and tougher maritime emissions regulations. Methanol is considered as a potential marine fuel, which has the ability to reduce SOx and CO2 emissions, reduce climate change effects, and achieve the objective of green shipping. This work proposes and combines the innovative combination system of direct methanol solid oxide fuel cells (SOFC), proton exchange membrane fuel cells (PEMFC), gas turbines (GT), and organic Rankine cycles (ORC) for maritime vessels. The system's primary power source is the SOFC, while the GT and PEMFC use the waste heat from the SOFC to generate useful power and improve the system's ability to use waste heat. Each component's thermodynamics model and the combined system's model are established and examined. The multigeneration system's energy and exergy efficiency are 76.2% and 30.3%, respectively. When compared to a SOFC stand-alone system, the energy efficiency of the GT and PEMFC system is increased by 19.2%. The use of PEMFC linked SOFC has significant efficiency when a ship is being started or maneuvered and a quick response from the power and propulsion plant is required.

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