• Title/Summary/Keyword: SO-MC

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Wilde the "Pervert": Oscar and Transnational (Roman Catholic) Religion

  • McCormack, Jerusha
    • Journal of English Language & Literature
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    • v.60 no.2
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    • pp.211-232
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    • 2014
  • In late Victorian England, a "pervert" meant two things. One meaning designated a person who "turned" or converted from one sect of Christianity to another. In Wilde's time this referred specifically to converts from the established state Church of England to the transnational Roman Catholic Church. The other, newer meaning designated someone who turned from conventional heterosexual relations to a (as yet unnamed) homosexual orientation. In the context of the late Victorian empire, both were considered dangerous. The rising social and political influence of Roman Catholicism appeared threatening as a transnational Church invading a national one. For the Anglican Church of England, this crisis was played out what came to be known as the Oxford Movement, still influential during Wilde's time as a student there from 1874 to 1878. What is interesting in Wilde's life, as in his work, is the way he himself played with the dangerous transgressions inherent in being a "pervert." Sexually, he was converted to same-sex love while still a married man. In terms of religion, he remained fascinated with Catholicism, allegedly converting on his death-bed. But what is provocative is way that Wilde used one "perversion" to play into another: so that in such works as The Picture of Dorian Gray and Salome, his version of a kind of anti-Catholic Catholicism becomes a site of sexual desire, and sexual desire expression for that kind of spirituality, which, as unrequited longing, can ultimately n find no object adequate to its imagination.

cAMP Response Element-Binding Protein- and Phosphorylation-Dependent Regulation of Tyrosine Hydroxylase by PAK4: Implications for Dopamine Replacement Therapy

  • Won, So-Yoon;You, Soon-Tae;Choi, Seung-Won;McLean, Catriona;Shin, Eun-Young;Kim, Eung-Gook
    • Molecules and Cells
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    • v.44 no.7
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    • pp.493-499
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    • 2021
  • Parkinson's disease (PD) is characterized by a progressive loss of dopamine-producing neurons in the midbrain, which results in decreased dopamine levels accompanied by movement symptoms. Oral administration of l-3,4-dihydroxyphenylalanine (L-dopa), the precursor of dopamine, provides initial symptomatic relief, but abnormal involuntary movements develop later. A deeper understanding of the regulatory mechanisms underlying dopamine homeostasis is thus critically needed for the development of a successful treatment. Here, we show that p21-activated kinase 4 (PAK4) controls dopamine levels. Constitutively active PAK4 (caPAK4) stimulated transcription of tyrosine hydroxylase (TH) via the cAMP response element-binding protein (CREB) transcription factor. Moreover, caPAK4 increased the catalytic activity of TH through its phosphorylation of S40, which is essential for TH activation. Consistent with this result, in human midbrain tissues, we observed a strong correlation between phosphorylated PAK4S474, which represents PAK4 activity, and phosphorylated THS40, which reflects their enzymatic activity. Our findings suggest that targeting the PAK4 signaling pathways to restore dopamine levels may provide a new therapeutic approach in PD.

Overinvestment Propensity and Firm's Value

  • LEE, Ki Se;JEON, Seong Il
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.3
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    • pp.49-59
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    • 2021
  • This study empirically analyzes the effect of firm overinvestment propensity on the value relevance of capital investment. In order to verify this point, this study attempts to analyze the value relevance of overinvestment firms' capital investments. The analysis was performed according to the model of Biddle et al. (2009) and McNichols and Stubben (2008) on overinvestment propensity for analysis, and the results are as follows. First, in terms of overinvestment, corporate capital investment shows negative value relevance, so the excessive investments above reasonable levels have reduced firm's value. In contrast, the value relevance for capital investment showed a positive value for firms whose managerial propensity changed, that is, from under-investment in the previous year, it shifted to overinvestment in the current year. Second, as a result of analyzing the value relevance of the investment increase according to the investment propensity, the overinvestment firms showed negative values and the underinvested firms showed positive values; thus, the value relevance of the increase in investment was opposite to the investment propensity of the firm. These findings confirm that the stock market differentially evaluates investment efficiency according to investment propensity, continuity, and investment alterations, and reflects it appropriately in the firm's value.

Can Angular Deformity Due to Sacrococcygeal Fracture Cause Permanent Impairment? : Current State and Problems in Korea

  • Cho, Dosang
    • Journal of Korean Neurosurgical Society
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    • v.65 no.2
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    • pp.173-179
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    • 2022
  • Disabilities can emerge due to traumatic spinal fractures. In terms of sacrococcygeal spine, because of its unique anatomic structure with minimal movement, the possibility for it to have a disability is relatively low. In Korea, unlike most disability criteria, private insurance companies acknowledge angular deformities caused by vertebral fractures as disabilities according to their degree, so there were several cases where patients required compensation, arguing angular deformity caused by sacrococcygeal fracture, which in some cases led to legal conflicts. Except the Act Welfare of Persons with Disabilities which recognizes only severe angular deformity affecting internal organs as disability and the industrial accident disability evaluation which does not recognize coccygeal fracture as disability but rarely recognizes sacral vertebra deformity equivalent to compressive deformation, there is little or no case where angular deformity is recognized as disability. Given the impairment evaluation standards in social insurance, McBride system, American Medical Association (AMA) guides, and newly proposed standards by the Korean Academy of Medical Sciences (KAMS), the most contentious point in the general terms and conditions of private insurance is spinal deformity. To overcome controversy over disability evaluation, the private insurance sector is now applying criteria for axial skeleton to sacrococcygeal vertebrae through revision of standards. Under these circumstances, it is fair to recognize sacrococcygeal fracture as impairment in terms of the pelvis only when the fracture leaves serious deformity and neurological symptoms with clear relevancy. Though it may not be easy to develop accurate disability evaluation standards, improvement is necessary to remove any irrationalities and make the standards as objective as possible.

A Generalized Multicarrier Communication System - Part III: Dual Symbol Superposition Block Carrier Transmission with Frequency Domain Equalization

  • Imran Ali
    • International Journal of Computer Science & Network Security
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    • v.24 no.9
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    • pp.41-49
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    • 2024
  • This paper proposes dual symbol superposition block carrier transmission with frequency domain equalization (DSS-FDE) system. This system is based upon χ-transform matrix, which is obtained by concatenation of discrete Hartley transform (DHT) matrix and discrete Fourier transform (DFT) matrices into single matrix that is remarkably sparse, so that, as it will be shown in this paper, it only has non-zero entries on its principal diagonal and one below the principle anti-diagonal, giving it shape of Latin alphabet χ. When multiplied with constellation mapped complex transmit vector, each entry of resultant vector is weighted superposition of only two entries of original vector, as opposed to all entries in conventional DFT based OFDM. Such a transmitter is close to single carrier block transmission with frequency domain equalization (SC-FDE), which is known to have no superposition. The DSS-FDE offers remarkable simplicity in transmitter design and yields great benefits in reduced complexity and low PAPR. At receiver-end, it offers the ability to harvest full diversity from multipath fading channel, full coding gain, with significant bit error rate (BER) improvement. These results will be demonstrated using both analytical expressions, as well as simulation results. As will be seen, this paper is Part III of three-paper series on alternative transforms for multicarrier communication (MC) systems.

Effect of Gypsum, Popped Rice Hull and Zeolite on Soil Aggregation in Reclaimed Tideland (간척지 토양에서 석고, 팽화왕겨 및 Zeolite 처리가 토양의 입단형성에 미치는 영향)

  • Kim, Seong-Jo;Baek, Seung-Hwa;Lee, Sang-Uk;Kim, Dae-Geun;Na, Young-Joon
    • Korean Journal of Soil Science and Fertilizer
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    • v.38 no.5
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    • pp.231-237
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    • 2005
  • Gypsum treated to fine sandy loam increased the fornation of >2 mm aggregates in $1,550kg\;CaSO_4{\cdot}2H_2O\;10a^{-1}$ (Kbfg1) and $3,100kg\;CaSO_4{\cdot}2H_2O\;10a^{-1}$ (Kbfg2) to compare with control, Kc, at 60DAT, and bigger aggregates in general at 90DAT. The higher treatment of gypsum level, the <0.1 mm aggregates were less decreased as in Kbfg1, Kbfg2, and $6,200kg\;CaSO_4{\cdot}2H_2O\;10a^{-1}$ (Kbfg3) and aggregates of 0.25->2 mm were increased with increasing level of gypsum with more effective in Kbfg2 and Kbfg3 at 120DAT. Gypsum treated to silt loam increased aggregates of 2.0-1.0 and 1.0-0.5 mm in $3,100kg\;CaSO_4{\cdot}2H_2O\;10a^{-1}$ (Mbfg2) to compare with control (Mc), at 60DAT. Degrees of aggregation from 0.5-0.25 mm to >2 mm aggregates at 90DAT were distinctly higher. The higher treatment of gypsum level accelerated more aggregation of silt loam soil, and aggregates of 0.5-0.25 mm was most increased in Mbfg2 at 120DAT. Popped rice hulls treated to fine sandy loam increased aggregates of 2.0-1.0 mm in plots of $1,000kg\;10a^{-1}$ (Kbfhl) only to compare with control (Kc), at 60DAT, and aggregates of >2 mm and 2.0-1.0 mm Kbfh1 at 90DAT. At 120DAT, aggregation by popped rice hulls was most effective in Kbfbl pot. Popped rice hulls treated to silt loam increased in aggregates of >2 mm and 2.0-1.0 mm in $2000kg\;10a^{-1}$, Mbfb2 to compare with control, Mc, at 60DAT. Degrees of aggregation by popped rice hulls at 90DAT were higher in $1,000kg\;10a^{-1}$, Mbfh1, and Mbfh2, and at 120DAT was in $3,000kg\;10a^{-1}$, Mbfb3. Zeolite treatment with popped rice hulls, $1,500kg\;10a^{-1}$, increased in >2.0 mm aggregates in $1,000kg\;10a^{-1}$, Kbfbz1, $2,000kg\;10a^{-1}$, Kbfbz2, $3,000kg\;10a^{-1}$, Kbfhz3, and Mbfbz1, $1,000kg\;10a^{-1}$, Mbfbz2, $2,000kg\;10a^{-1}$, and $3,000kg\;10a^{-1}$, Mbthz3, to compare with control (Kc and Mc), at 60DAT. irrespective of soil texture. At 90DAT, >2.0-0.5 mm aggregates increased in Kbfhz1 of fine sandy loam. aggregates of >0.25 mm in $200kg\;10a^{-1}$ (Mbfbz1), $400kg\;10a^{-1}$ (Mbfhz2), $800kg\;10a^{-1}$ (Mbfhz3) of silt loam increased with the level of zeolite treatment. At 120DAT, the effect of zeolite treated to both soils showed the decrease of <0.1 mm aggregates. As the result, soil amendments for soil aggregation was more effective in the order of popped rice hulls+Zeolite > gypsum > popped rice hulls in fine sandy loam, and in the order of gypsum > popped rice huUs+zeolite > popped rice hulls in silt loam, respectively.

A study on the compressive capacity of structural skin timber for the furniture manufacturing and heavy timber construction (가구 및 중목구조용 실대재 스킨팀버의 압축 성능에 관한 연구)

  • Kim, Gwang-Chul
    • Journal of the Korea Furniture Society
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    • v.21 no.4
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    • pp.273-283
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    • 2010
  • Structural larger timber have some weak points as like much longer drying time at lower MC(15%), a considerable check developing and the difficulty for the chemicals injection, so it is necessary to develop lighter structural size member for using the new Hanok, heavy timber construction, living necessaries, furniture and industrial goods. The developed skin timber can be a good raw material for those uses. Skin timber is a hollowed timber which be bored out of its considerable cross-sectional area. The intention of this study was the evaluation of compressive capacity of skin timber. Specially, skin timbers which have more than 200mm in sizes were used to analyze the compressive capacity. From the results of this study, the following conclusions have been made: 1. Though considerable inner parts were bored out, both pine skin timber and larch skin timber showed a good compressive capacity to that of non-bored solid timber. 2. According to ASTM, pine skin timber showed various failure types, but Splitting type, Brooming and end rolling type were main failure types for the larch skin timber. 3. Pine skin timber didn't show the significance between cylindrical shape and rectangular shape, but larch skin timber showed the significance between two shapes. Therefore, for the larch skin timber, cylindrical shape and rectangular shape should be used as a column uses and beam uses respectively. 4. Pine skin timber and larch skin timber didn't show the significance on the compressive capacity. There is not much difference of compressive capacity between them, so it can be possible to select on the user convenience.

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Implementation and Performance Analysis of High-availability System for Mission Computer (임무컴퓨터를 위한 고가용 시스템의 구현 및 성능분석)

  • Jeong, Jae-Yeop;Park, Seong-Jong;Lim, Jae-Seok;Lee, Cheol-Hoon
    • The Journal of the Korea Contents Association
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    • v.8 no.8
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    • pp.47-56
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    • 2008
  • MC(Mission Computer) performs important function in avionics system which tactic data processing, image processing and managing navigation system etc. In general, the fault of SPOF(Single Point Of Failure) in unity system can lead to failure of whole system. It can cause a failure of a mission and also can threaten to the life of the pilot. So, in this paper, we design the HA(Hight-availability) system so that dealing with the failure. And we use HA software like Heartbeat, Fake, DRBD and Bonding to manage HA system. Also we analyze the performance of HA system using the FDT(Fault Detection Time) for fast fault detection and MTTR(Mean Time To Repair) for mission continuity.

The perceptual span during reading Korean sentences (우리글 읽기에서 지각 폭 연구)

  • Choi, So-Young;Koh, Sung-Yrong
    • Korean Journal of Cognitive Science
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    • v.20 no.4
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    • pp.573-601
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    • 2009
  • The present study investigated the perceptual span during reading Korean, using the moving-window display change technique introduced by McConkie and Rayner(1975). Eight different window sizes were used in Experiment 1. They were 3, 5, 7, 9, 11, 13, 15 characters in size and the full line. Reading rate, number of fixation, saccadic distance, fixation duration were compared between each window-size condition and the full line condition. The reading rate was no higher in the full line condition than in the 15 character condition but was higher than in the other conditions. The number of fixations was no larger in the full line condition than in the 15 character condition, had a tendency to be larger than in the 13 characters condition, and was more than in the other conditions. The result pattern of the saccadic distance based on character was the same as that of the reading rate, and the saccadic distance based on the pixel was the same as that of the number of fixation. Similarly, for fixation duration, there was no differences between whole line condition and 15, 13, and 11 characters condition. The fixation duration had a tendency to be shorter in the 9 characters, and was shorter in the 7, 5, and 3 characters conditions than whole line condition. In Experiment 2, based on asymmetry of perceptual span, the 6 different window sizes(0, 1, 2, 3, 4 characters in size and the full line) were used. There was a difference only between the 0 condition and the other conditions in the reading rate, number of fixations, fixation duration. Considering the pattern of eye-movement measures above, the perceptual span of Korean readers extends about 6-7 characters to the right of fixation and 1 character to the left of fixation.

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A study on the Compressive Strength of the Improved Skin-timber (개량 스킨팀버의 압축 강도에 관한 연구)

  • Kim, Gwang-Chul
    • Journal of the Korean Wood Science and Technology
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    • v.38 no.4
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    • pp.282-291
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    • 2010
  • As compared with existing center-boring timber, skin timber which be hollowed out of its considerable inner parts has some merits as like short drying time, less developed checks during drying, a advantage of lower MC (8~%), more easy injection of chemicals, a possibility of using as a lighter structural heavy timber including Hanok and heavy timber construction, a possibility for the various living necessaries and furniture materials. However, development of hybrid skin timber is required for using as a value-added materials and giving a confidence for the structural safety of skin timber to general user. Thus, improved pine skin timber (IPST) and improved larch skin timber (ILST) were manufactured using the lighter steel plate possible. And compressive capacity of improved skin timber was analyzed. From the results of this study, the following conclusions have been made: 1. Both of IPST and ILST can give a uniformity of material capacity compared with non-treated skin timber. 2. Both IPST and ILST, there was not statistical significancy among the thickness of steel plate. Therefore, it concluded that it was not necessary to use thicker steel plate. 3. There was also not statistical significancy between IPSR and ILST, so it need not to be selective about the species of improved skin timber. 4. IPST showed various failure types, but most failure types of ILST is a splitting type.