• Title/Summary/Keyword: SLA method

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Analysis of Swine Leukocyte Antigen Haplotypes in Yucatan Miniature Pigs Used as Biomedical Model Animal

  • Choi, Nu-Ri;Seo, Dong-Won;Choi, Ki-Myung;Ko, Na-Young;Kim, Ji-Ho;Kim, Hyun-Il;Jung, Woo-Young;Lee, Jun-Heon
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.3
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    • pp.321-326
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    • 2016
  • The porcine major histocompatibility complex (MHC) is called swine leukocyte antigen (SLA), which controls immune responses and transplantation reactions. The SLA is mapped on pig chromosome 7 (SSC7) near the centromere. In this study, 3 class I (SLA-1, SLA-3, and SLA-2) and 3 class II (DRB1, DQB1, and DQA) genes were used for investigation of SLA haplotypes in Yucatan miniature pigs in Korea. This pig breed is a well-known model organism for biomedical research worldwide. The current study indicated that Korean Yucatan pig population had 3 Class I haplotypes (Lr-4.0, Lr-6.0, and Lr-25.0) and 3 class II haplotypes (Lr-0.5, Lr-0.7, and Lr-0.25). The combinations of SLA class I and II haplotype together, 2 homozygous (Lr-4.5/4.5 and Lr-6.7/6.7) and 3 heterozygous (Lr-4.5/6.7, Lr-4.5/25.25, and Lr-6.7/25.25) haplotypes were identified, including previously unidentified new heterozygous haplotypes (Lr-4.5/4.7). In addition, a new SLA allele typing method using Agilent 2100 bioanalyzer was developed that permitted more rapid identification of SLA haplotypes. These results will facilitate the breeding of SLA homozygous Yucatan pigs and will expedite the possible use of these pigs for the biomedical research, especially xenotransplantation research.

SLA Homozygous Korean Native Pigs and Their Inbreeding Status Deduced from the Microsatellite Marker Analysis

  • Jung, Woo-Young;Lim, Hyun-Tae;Lim, Jae-Sam;Kim, Sung-Bok;Jeon, Jin-Tae;Lee, Jun-Heon
    • Journal of Animal Science and Technology
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    • v.52 no.6
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    • pp.451-457
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    • 2010
  • The porcine MHC (Major Histocompatibility Complex), encoding the SLA (Swine Leukocyte Antigen) genes, is one of the most significant regions associated with immune rejection in relation to transplantation. In this study, three SLA class I (SLA-1, SLA-3, SLA-2) loci and three SLA class II (DRB1, DQB1, DQA) loci were investigated in the previously unidentified Korean native pig (KNP) population that was closely inbred in the Livestock Technology Research Station in Cheongyang, Korea. Total thirteen KNPs from four generations were genotyped for the SLA alleles and haplotypes were investigated using PCR-SSP (Sequence-Specific Primer) method. The results showed that all of these KNPs had Lr-56.30/56.30 homozygous haplotype, indicating high level of inbreeding in the SLA genes. The inbreeding status of these animals was also investigated using microsatellite (MS) markers. From the 50 MS markers investigated, 17 MS markers were fixed in all generations and the fixed alleles are increased as 26 loci for the fourth generation. Two MS markers, S0069 and SW173, were heterozygous for all the animals tested. Observed and expected heterozygosities were calculated and the average inbreeding coefficients for each generation were also calculated. In the fourth generation, the average inbreeding coefficients was 0.732 and this may increase with further inbreeding process. Analysis of the SLA haplotypes and MS alleles can give important information for breeding the pigs for xenotransplantation studies.

A Specification and Exchange Method for Supporting SLA in SaaS Environment (SaaS 환경에서 SLA 보장을 위한 명세 및 교환 방법)

  • Nam, Taewoo;Kang, Taejun;Jang, Moonsoo;An, Youngmin;Yeom, Keunhyuk
    • Journal of Software Engineering Society
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    • v.26 no.2
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    • pp.45-52
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    • 2013
  • A cloud computing service provider must assure Service Level Agreement (SLA) to provide reliable and consistent quality of service to a user. The SLA is a contract between the user and the service provider that connects to assure constant level such as availability to target provided service. The cloud computing is classified into IaaS, PaaS, and SaaS according to IT resources of the various cloud service. The existing SLA is difficult to reflect quality factors of service because it only considers factors about the physical Network environment. In this paper, we suggest the UDDI-based interchange process with the architecture and the specification language having a XML schema for the SLA specification. The quality requirements of SaaS are defined by a proposed specification language in the cloud environment. It is stored in the repository of a quality specification and exchanged on during the service binding time based on the exchange architecture.

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A Study on Deducing Quality Improvement Candidate Factors of IT Service Management System Based on SLA (SLA기반 IT서비스관리시스템의 품질개선 후보요인 도출방안 연구 : K사를 중심으로)

  • Jung, Sang-Chul;Kim, Myung-Seuk
    • Journal of Information Technology Applications and Management
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    • v.15 no.4
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    • pp.103-121
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    • 2008
  • Service Providers need to monitor the level of consumer's satisfaction on service they provide continuously and they use appropriate method to measure their operating status. They have to make a plan on their resource and infrastructure to provide their service in the right place at the right time whenever they need. Most previous studies on IT service quality are mainly focused on criteria or levels of quality measurement even though those criteria and levels should be set by considering consumer's needs. And considering for consumer's needs with managerial factors was not found on those studies. So, we suggest deducing quality factors for continuous improvement of IT service management system in this paper as identify the relative priority using QFD method which consider consumers' voices and managerial factors when decide quality factors of IT service management system introduced SLA. We also confirm that our suggestion is practicable and applicable for current operation by case study.

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A Study of QoS Mapping based on SLA in B3G Networks (B3G 네트워크에서 SLA 기반 QoS 매핑을 위한 연구)

  • Moon, Hyun-Joo;Lee, Jin-Kwan;Jung, Kyu-Chul;Lee, Jong-Chan;Park, Sang-Joon;Shin, Seong-Yoon
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.3
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    • pp.157-165
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    • 2011
  • The QoS management is an agreement of service user and service provider in B3G networks, and service provider must support proper the network service to service users by the agreement facts. The service provider must provide the QoS method to maintain the agreed service, which manages the detail method of system level from policy level. By the agreement of service policy, the service provider can give the QoS to the service customer with the service agreement. Hence, in this paper we propose a QoS mapping method of heterogeneous networks to provide the customer service through the service agreement based on the SLA of B3G networks.

An efficient network dimensioning method for DiffServ over MPLS networks (MPLS 기반 DiffServ망에서의 효율적인 네트워크 Dimensioning에 관한 연구)

  • 조병일;유상조;정연화
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.5B
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    • pp.435-447
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    • 2003
  • Current existing network dimensioning method simply relies on long-time measurement data or uses average traffic characteristics of users. In this paper, we propose an efficient network dimensioning method for DiffServ over MPLS networks. First, User's SLA information is distributed from edge nodes to core nodes according to the proposed algorithm. Then at each link, class-based capacity planning is performed. For capacity planning, we proposed sets of network design parameters for DiffServ classes and bandwidth allocation schemes that are most suitable for each class. We have developed a DiffServ over MPLS network design tool using the proposed method. Simulation results show that our proposed method is able to design efficiently the required class link resources.

The Method for Recommend of Contact Area According to the User's SLA(S-RCA) based on a Moving Path Prediction Service (이용자의 과거 위치 정보와 이용자별 SLA(Sevice Level Agreement)를 지원하는 동적 예측서비스 기반의 접촉 지역 추천(S-RCA) 기법)

  • Cho, Kyeong Rae;Lee, Jee Hyong
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.9 no.2
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    • pp.41-54
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    • 2013
  • In this paper, We collected location based services of the user's past moving paths through the GPS. Using the collected by location-based services through the analysis of the similarity between the user's of service level agreement recommended of mobile contact area(SLA) proposed that can be. S-RCA method based on Service Level Agreement of the users in order to provide the service user's path distance, time, and to predict the direction of the movement paths and collect. The data collected by the interests and requirements of users through classification with the same interests and the needs of users to move between the analysis of the similarity between the path is used to analyze the results of analysis of the path-specific tolerance range (distance, time, and space) is determined according to the difference in the contact area. From a small area of the error range for users first to recommended and through their smartphones recommended contact area (S-RCA) to meet with the other party to make a choice of recommended methods. We verify through experiments that proposed method(S-RCA) a valid and reliable mobile contact area were recommended.

A Study on the Changes in Surface Properties According to Post-treatment of SLA 3D Printing Materials (SLA 3D 프린팅 소재의 후처리에 따른 표면특성 변화 연구)

  • Bae, Seo Jun;Im, Do Jin
    • Korean Chemical Engineering Research
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    • v.60 no.1
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    • pp.132-138
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    • 2022
  • In this study, a basic study was performed to systematically compare the changes in surface properties according to the post-processing method of the stereolithography (SLA) printing method, which is a photocuring 3D printing method, and to provide information on the post-processing method suitable for the application. Although it was possible to improve some of the transparency of the SLA-type output by regularly changing the irregular microstructure of the surface through polishing, it was difficult to secure sufficient transparency like glass. The change in contact angle characteristics due to grinding showed a tendency to slightly increase as the grinding time increased and the particle size of the sandpaper used was small, but the variation between samples was large and the average contact angle was 77~90°, showing no statistically significant difference. Surface treatment methods other than polishing were tried, and it was confirmed that it was possible to easily and simply improve the transparency by applying a commercially available vehicle scratch remover or silicone oil. In addition, a method for securing high transparency such as glass by using a scratch remover after sequential grinding while reducing the particle size of the sandpaper was proposed. Finally, even after surface treatment through polishing and various methods, it was difficult to secure a contact angle of 90° or more.

Service Level Agreement Specification Model of Software and Its Mediation Mechanism for Cloud Service Broker (클라우드 서비스 브로커를 위한 소프트웨어의 서비스 수준 합의 명세 모델과 중개 방법)

  • Nam, Taewoo;Yeom, Keunhyuk
    • Journal of KIISE
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    • v.42 no.5
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    • pp.591-600
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    • 2015
  • SLA (Service Level Agreement) is an essential factor that must be guaranteed to provide a reliable and consistent service to user in cloud computing environment. Especially, a contract between user and service provider with SLA is important in an environment using a cloud service brokerage. The cloud computing is classified into IaaS, PaaS, and SaaS according to IT resources of the various cloud service. The existing SLA is difficult to reflect the quality factors of service, because it only considers factors about the physical Network environment and have no methodological approach. In this paper, we suggested a method to specify the quality characteristics of software and proposed a mechanism and structure that can exchange SLA specification between the service provider and consumer. We defined a meta-model for the SLA specification in the SaaS level, and quality requirements of the SaaS were described by the proposed specification language. Through case studies, we verified proposed specification language that can present a variety of software quality factors. By using the UDDI-based mediation process and architecture to interchange this specification, it is stored in the repository of quality specifications and exchanged during service binding time.

A Study on development of privacy indicators in the context of cloud service level agreement (클라우드 개인정보보호를 위한 SLA 지표 개발)

  • Kim, Jungduk;Park, Dae-Ha;Youm, Heung-Youl
    • Journal of Digital Convergence
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    • v.13 no.2
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    • pp.115-120
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    • 2015
  • As the cloud services, the underlying technology of the digital convergence environment, have been widely adopted in the business, personal information protection has been recognized as one of the major issues to resolve. When cloud services are used to process the personal information, the personal information protection law speculates the establishment of a contract or service level agreement(SLA). This research presents 7 privacy indicators and 13 metrics which can be included in cloud SLA, based on the analysis of related regulation and standards and the SMART(Specific, Measurable, Action-oriented, Relevant and Timely) model. The proposed indicators are examined using the Focus Group Interview method in terms of materiality and feasibility. The results show that all the proposed indicators are meaningful and useful.