• The Korean Journal of Nuclear Medicine
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• v.16 no.2
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• pp.63-70
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• 1982

To evaluate the diagnostic usefulness and significance of quantitative sacroiliac joint scintigraphy in the assessment of sacroiliitis, we measured Sacroiliac Joint/Sacrum Uptake Ratio(SIS Ratio) by region of interest(ROI) method using $^{99m}Tc-methylene$ diphosphonate. The observed results were as follows: 1. Using ROI method, the SIS ratios for the control group of 65 persons were $1.05{\pm}0.08$(left) and $1.06{\pm}0.07$(right) which were narrower in range than those of slice method $(mean{\pm}S.D.)$. 2. The effects of age, gender and laterality on SIS ratio were not significant. 3. In left side, one of 6 patients with rheumatoid arthritis had SIS ratio in excess of 2 standard deviation of normal control group, and remainder had SIS ratios within normal limit. In right side, 3 patients had SIS ratios in excess of 2 standard deviation of normal control group, and remainder, within normal limit. 4. In both sacroiliac joint, 2 of 3 patients having sacroiliitis clinically with Reiter's syndrome whose pelvis A-P X-ray findings showed normal had high SIS ratios (left/right; 1.31/1.69, 1.90/1.80), but SIS ratio of one patient who had no evidence of sacroiliitis clinically was within normal limit. 5. In 6 patients with ankylosing spondylitis in both sacroiliac joints, 4 whose pelvis A-P Xray findings showed severe sclerotic change of sacroiliac joints had SIS ratio within normal limit or below that of normal control group, and SIS ratios of 2 patients whose pelvis A-P X-ray findings showed were increased. 6. 4 of 5 patients with low back pain of which cause could not be evaluated clinically and radiologically had SIS ratios in excess of that of normal control group. It would be concluded that quantitative sacroiliac joint scintigraphy is useful and sensitive screening method in the diagnosis as well as in the assessment clinical activity of sacroiliitis.

• Polymer(Korea)
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• v.34 no.3
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• pp.282-288
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• 2010

The porcine small intestinal submucosa (SIS) has been widely used as a biomaterial without immuno rejection responses and hyalunonic acid (HA) can be used as biocompatible materials to regenerate tissue. We developed the SIS sponge and HA loaded SIS sponges (SIS/HA) for the possibility of the application of the tissue engineering using annulus fibrosus (AF). SEM observation shows that SIS and SIS/HA sponges have interconnected and open pores. We demonstrated the presence of HA in SIS/HA sponge from C-O functional group observed by the FTIR analysis. In conclusion, we suggest that SIS/HA sponge may be useful to tissue engineering using AF cell. This may be due to the enhanced biocompatibility and higher water retention capacity of HA.

• Polymer(Korea)
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• v.28 no.2
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• pp.194-200
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• 2004

Porcine small intestine submucosa (SIS) has been widely used as a biomaterial without immunorejection responses. Crosslinked SIS sponges were characterized for the possibility of the bio-interactive wound dressings and tissue engineered scaffolds. SIS powders were dissolved in 3% acetic acid aqueous solution at 48hrs followed by pouring into mold and then fabricated by freeze-drying method. SIS sponge was prepared by crosslinked with 1-ethyl-(3-3-dimethyl aminopropyl) carbodiimide hydrochloride (EDC) solution (deionized water: ethanol=5:95) with 1-100mM concentration for 24 hrs and Iyophilized. SIS sponges were characterized by scanning electron microscopy, differential scanning calorimeter, and Fourier transform infrared spectrometer and were tested their porosity and water absorption ability. It was observed that the concentration of EDC might be exceeded 50 mM to get good physical characteristics. In conclusion, it seems that SIS sponge could be very useful for the applications of wound healing and tissue construction.

• Journal of The Korean Astronomical Society
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• v.29 no.spc1
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• pp.413-414
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• 1996

A 230 GHz SIS tunnel junction receiver has been being developed for radio astronomy in Nagoya University. In this heterodyne receiver, we use a $\~$1/3 reduced hight rectangular waveguide SIS mixer with two tuning elements as front end. The mixer block with SIS junction was cooled to 4K with a closed cycle He-gas refrigerator. So far, a double sideband receiver noise temperature lower than l00K in 222-237 GHz is obtained. The receiver exhibits a best DSB noise temperature of 69K at 236 GHz as well as 228 GHz.

• Journal of Astronomy and Space Sciences
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• v.23 no.1
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• pp.19-28
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• 2006

The noise temperature of existing millimeter-wave receivers is already within two or three times quantum noise limit. One of practical ways to increase the observation speed of single dish radio telescope without longer integration time is use of multi-beam focal plane array receiver as demonstrated in several large single dish radio telescopes. In this context the TRAO (Taeduk Radio Astronomy Observatory), which operates a 143n Cassegrain radio telescope, is planning to develop a 4 x 4 beams focal plane array SIS receiver system for 86-115 GHz band. Even though millimeter-wave HEMT LNA-based receivers approach the noise temperature comparable to the SIS receiver at W-band, it is believed that the receiver based on SIS mixer seems to offer a bit more advantages. The critical part of the multi-beam array receiver will be sideband separating SIS mixers. Employing such a type of SIS mixer makes it possible to simplify the quasi-optics of receiver. Otherwise, an SSB filter should be used in front of the mixer or some sophisticated post-processing of observation data is needed. In this paper we will present a preliminary design concept and components needed for the development of a new 3 mm band multi-beam focal plane array receiver.

• Applied Chemistry for Engineering
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• v.5 no.5
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• pp.851-856
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• 1994

Compatibility and viscoelasticity in non-solvent type pressure sensitive adhesive of styrene-isoprene-styreno(SIS) block copolymer with tackifier resin were investigated. In the isoprene phase of SIS block copolymer, it was found that it's compatibility with $C^5$ petroleum resin was good, but that with Coumarone-indents resin was not so good. The magnitudes of peel strength, tack, and holding power were as follows : $C^5$ petroleum resin>rosin ester resin>coumarone-indene resin. The tackifier resin with good compatibility in rubber phase was also effective. However, with plateau modulus value of $1{\times}10^6-3{\times}10^6dyn/cm^2$, the effect of pressure sensitive adhesives was excellent.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.1
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• pp.273-276
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• 2014

Ellagic acid has been shown to inhibit tumor cell growth. However, the underlying molecular mechanisms remain elusive. In this study, our aim was to investigate whether ellagic acid inhibits the proliferation of MCF-7 human breast cancer cells via regulation of the TGF-${\beta}$/Smad3 signaling pathway. MCF-7 breast cancer cells were transfected with pEGFP-C3 or pEGFP-C3/Smad3 plasmids, and treated with ellagic acid alone or in combination with SIS3, a specific inhibitor of Smad3 phosphorylation. Cell proliferation was assessed by MTT assay and the cell cycle was detected by flow cytometry. Moreover, gene expression was detected by RT-PCR, real-time PCR and Western blot analysis. The MTT assay showed that SIS3 attenuated the inhibitory activity of ellagic acid on the proliferation of MCF-7 cells. Flow cytometry revealed that ellagic acid induced G0/G1 cell cycle arrest which was mitigated by SIS3. Moreover, SIS3 reversed the effects of ellagic acid on the expression of downstream targets of the TGF-${\beta}$/Smad3 pathway. In conclusion, ellagic acid leads to decreased phosphorylation of RB proteins mainly through modulation of the TGF-${\beta}$/Smad3 pathway, and thereby inhibits the proliferation of MCF-7 breast cancer cells.

• Journal of the Korea Convergence Society
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• v.11 no.9
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• pp.325-332
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• 2020

This study aimed to identify the difference of scapular movements between tennis players with and without shoulder impingement syndrome(SIS) and to verify the effect of kinesiology taping applied to scapular. A total of 15 players were categorized in SIS group(n=7) and control(CON) group(n=8). The scapular movements evaluated using 3-dimensional motion analysis in the 5 events of the flat first serve before and after the application of taping. The male of SIS group(-7.31±1.19° and -5.28±1.08°, respectively) had tilted scapular more anteriorly compared to CON group(-0.98±5.38° and -0.44±3.52°, respectively) at the maximally humeral external rotation and the impact(Z=-2.309, p=.021 and Z=-2.309, p=.021, respectively). The scapular(-8.11±2.57°) of female in SIS group tilted more anteriorly than that of CON(-0.97±3.31°) group at the maximally humeral external rotation(Z=-2.121, p=.034). But the scapular movements had no statistical differences between before and after the application of taping.

• Journal of the Society of Disaster Information
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• v.16 no.3
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• pp.602-610
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• 2020

Purpose: This paper aims to develop an asphalt pavement system with reduced cracks, structural stability and waterproofing at sub-zero temperature conditions. Method: Under various temperature conditions, SIS polymer asphalt, normal asphalt, and guss asphalt were tested for adhesion strength of the binder and deformation strength of the mixture. Result: The adhesion strength of asphalt binder was higher in SIS polymer asphalt than that of normal asphalt and guss asphalt. The deformation strength of the asphalt mixture was almost the same as that of SIS polymer asphalt and normal asphalt. The energy absorption of the SIS polymer asphalt mixture was relatively higher than that of the normal asphalt mixture and the guss asphalt mixture. Conclusion: The maximum load of the SIS polymer asphalt mixture was lower than that of the guss asphalt mixture. However, in sub-zero temperature conditions, sufficient energy absorption was secured by stable load reduction. Therefore, it is expected to improve the durability of asphalt pavement by reducing the occurrence of microcracks with stable fracture behavior.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.30A no.10
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• pp.12-19
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• 1993

Because of their high sensitivity and moderate bandwidth, superconducting receivers with SIS (Superconductor Insulator Superconductor) tunnel junction mixer are now widely used for millimeter wave radio astronomy. In this paper we have introduced how to determine the parameters of SIS tunnel junction which have to be optimized to achieve a good mixer performance. From these results of optimized junction parameters determined by this methods, SIS junctions which consist of a series array of four Nb/Al-AlOx/Nb junctions with each area 3.4${\mu}m^{2}$ have been fabricated by SNEP (Selective Niobium Etching Process) and RIE (Reactive Ion Eching). Also we have tested their DC current-voltage characteristics. These SIS junctions will be used as a mixer for 100GHz band cosmic waves receiver.