Ellagic Acid Exerts Anti-proliferation Effects via Modulation of Tgf-Β/Smad3 Signaling in MCF-7 Breast Cancer Cells |
Zhang, Tao
(The Fourth Affiliated Hospital of Harbin Medical University)
Chen, Hong-Sheng (The Fourth Affiliated Hospital of Harbin Medical University) Wang, Li-Feng (Xin Hua Hospital Affiliated to Shang Hai Jiao Tong University School of Medicine) Bai, Ming-Han (The Fourth Affiliated Hospital of Harbin Medical University) Wang, Yi-Chong (The Fourth Affiliated Hospital of Harbin Medical University) Jiang, Xiao-Feng (The Fourth Affiliated Hospital of Harbin Medical University) Liu, Ming (The Fourth Affiliated Hospital of Harbin Medical University) |
1 | Maiti B, Li J, de Bruin A, Gordon F J, et al (2005). Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem, 280, 18211-20. DOI |
2 | Jinnin M, Ihn H, Tamaki K (2006). Characterization of SIS3, a Novel Specific Inhibitor of Smad3, and Its Effect on Transforming Growth Factor-1-Induced Extracellular Matrix Expression. Mol Pharmacol, 69, 597-607. |
3 |
Leaslc A, Abraham DJ (2004). TGF- |
4 | Li TM, Chen GW, Su CC, et al (2005). Ellagic acid induced p53/ p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells. Anticancer Res, 25, 971-9. |
5 | Muller H, Moroni MC, Vigo E, et al (1997). Induction of S-phase entry by E2F transcription factors depends on their nuclear localization. Mol Cell Biol, 17, 5508-20. |
6 | Narayanan BA, Re GG (2001). IGF-II down regulation associated cell cycle arrest in colon cancer cells exposed to phenolic antioxidant ellagic acid. Anticancer Res, 21, 359-64. |
7 | Su E, Han X, Jiang G (2010). The transforming growth factor beta 1-SMAD signaling pathway involved in human chronic myeloid leukemia. Tumor, 96, 659-66. |
8 | Tian F, DaCosta Byfield S, et al (2003). Reduction in Smad2/3Signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res, 63, 8284-A92. |
9 |
Xu Y, Pasche B (2007). TGF- |
10 | Yu B, Lane ME, Wadler S (2002). SU9516, a cyclin-dependent kinase 2 inhibitor, promotes accumulation of high molecular weight E2F complexes in human colon carcinoma cells. Biochem Pharmacol, 64, 1091-100. DOI |
11 | Adams LS, Phung S, Yee N, et al (2010). Blueberry phytochemicals inhibit growth and metastatic potential of MDA-MB-231 breast cancer cells through modulation of the phosphatidylinositol 3-kinase pathway. Cancer Res, 70, 3594-605. DOI |
12 | Chen HS, Liu M, Shi LJ, et al (2011). Effects of raspberry phytochemical extract on cell proliferation, apoptosis, and serum proteomics in a rat model. J Food Sci, 76, T192-8. DOI |
13 |
Derynck R, Zhang YE (2003). Smad-dependent and Smadindependent pathways in TGF- |
![]() |