• Asian-Australasian Journal of Animal Sciences
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• v.13 no.10
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• pp.1422-1428
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• 2000

This investigation was conducted to evaluate the shrimp flesh (SF) and shrimp by-product (SB) of the most abundant shrimp species (Metapenaeus affinis, Penaeus semisulcatus and Penaeus monodon) caught in Central Vietnam, with the emphasis on yield, gross and amino acid (AA) composition and effect of heat treatment. The results showed that the mean edible SF and SB (head and shells with tail) yields of the three shrimp species averaged 56.7 and 43.3%, respectively, of the total wet body weight, with the M. affinis generating the highest by-product yield (45.7%) and P. semisulcatus (40.6%) the lowest. Significant differences in dry matter (DM), crude protein (CP) and ash content were found between SF and SB. The DM content of SF (21.5%) was lower than of SB (24.9%) and the ash content (on a DM basis) of the SB in all shrimp species was more than three times that of the SF (p<0.05), whereas the CP content was almost twice as high in the SF as compared with the SB (p<0.05). The SB of the three species contained (on a DM basis) between 44.0 and 49.8% CP (p<0.05) and between 13.5 and 18.1% chitin (p<0.05). The Ca content of SB differed also between species (p<0.05). On average, the sum of AA in SB corresponded to 89.3% of the CP and essential AA accounted for about 50% of the total AA. The most abundant AA were arginine, aspartic and glutamic acids, which accounted for 33% of the total AA. Minor, but significant differences in some AA concentrations of SB between species were observed (p<0.05). With the exception of the DM and ether extract content, all other chemical constituents of entire shrimp, SF and SB were not significantly affected by heat treatment (p>0.05).

• Journal of Ginseng Research
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• v.22 no.3
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• pp.188-192
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• 1998

We established the model of clonogenic assay with human tumor cell line such as Calu-3 (lung carcinoma), HEC- lB (endometrial adenocarcinoma) , HEp-2 (larnyx carcinoma), Hs-5787 (breast carcinoma), K-562 (chronic myelogenous leukemia), SF-188 (brain carcinoma), SNU-1 (stomach carcinoma) and WiDr (colon carcinoma) . We investigated growth inhibition of solvent (EtOH, MeOH) and water (100$^{\circ}C$, 121$^{\circ}C$) extracts from Korean red ginseng by clonogenic assay. The results of clonogenic assay showed that EtOH extract had growth inhibition against Calu-3, SF-188 and SNU-1, MeOH extract had growth inhibition against Calu-3, Hs-5787, K-562, and WiDr, but water extract at 100$^{\circ}C$ and water extract at 121$^{\circ}C$ had not growth inhibition against used cell lines.

• The Korean Journal of Food And Nutrition
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• v.24 no.4
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• pp.551-558
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• 2011

This present study was performed to analyze the efficiency and volatility of a porous film containing $Chamaecyparis$ $obtusa$ extract as a method to effectively package food compounds. Phytoncide was contacted the state of gas and showed effective antimicrobial properties. Limonene can be distilled without decomposition as a relatively stable terpene and was one of the extract components. $Chamaecyparis$ $obtusa$ essential oil. The optimal solvent composition was a ratio 5:20:0.3 of T-500:ethanol:hardener to effectively manufacture film containing phytoncide essential oil and the minimum antibacterial concentration was 2%. The films were made under different conditions(A-50LF1, A-25SF2, B-50SF1, C-50LF1, C-25SF2 and D-50SF1) containing phytoncide and the amounts of limonene inside the 1-L reaction chamber depending on storage were measured by gas chromatography-mass selective detention. The results showed that the 25SF2(width, 25 mm; length, 20 cm) revealed more amount of limonene compared with 50LF1(width 50 mm, length 20 cm). We confirmed that the gas emission amount showed a better layer on the film side than on the internal film. An effect of film thickness on phytoncide emissions was observed in that the amounts was less than the expectation for a thicker film at the beginning time, but the emitting amounts increased with increasing storage periods. In the storage testing of various films at $35^{\circ}C$ and 70% humidity for 14 days, 25SF2 showed longer preservation compared with that of 50LF in the case of bread. $C.$ $obtusa$ essential oil is a useful fresh ingredients, hence, analysis of limonene emission kinetics from various film was helpful to develop films with an optimal antimicrobial effect, and will allow application of such films in food packaging systems.

• International Journal of Stem Cells
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• v.16 no.1
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• pp.52-65
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• 2023

Background and Objectives: Epithelial-Mesenchymal transition (EMT) is one of the origins of myofibroblasts in renal interstitial fibrosis. Mesenchymal stem cells (MSCs) alleviating EMT has been proved, but the concrete mechanism is unclear. To explore the mechanism, serum-free MSCs conditioned medium (SF-MSCs-CM) was used to treat rat renal tubular epithelial cells (NRK-52E) fibrosis induced by transforming growth factor-β1 (TGF-β1) which ameliorated EMT. Methods and Results: Galectin-3 knockdown (Gal-3 KD) and overexpression (Gal-3 OE) lentiviral vectors were established and transfected into NRK-52E. NRK-52E fibrosis model was induced by TGF-β1 and treated with the SF-MSCs-CM for 24 h after modelling. Fibrosis and autophagy related indexes were detected by western blot and immunocytochemistry. In model group, the expressions of α-smooth muscle actin (α-SMA), fibronectin (FN), Galectin-3, Snail, Kim-1, and the ratios of P-Akt/Akt, P-GSK3β/GSK3β, P-PI3K/PI3K, P-mTOR/mTOR, TIMP1/MMP9, and LC3B-II/I were obviously increased, and E-Cadherin (E-cad) and P62 decreased significantly compared with control group. SF-MSCs-CM showed an opposite trend after treatment compared with model group. Whether in Gal-3 KD or Gal-3 OE NRK-52E cells, SF-MSCs-CM also showed similar trends. However, the effects of anti-fibrosis and enhanced autophagy in Gal-3 KD cells were more obvious than those in Gal-3 OE cells. Conclusions: SF-MSCs-CM probably alleviated the EMT via inhibiting Galectin-3/Akt/GSK3β/Snail pathway. Meanwhile, Gal-3 KD possibly enhanced autophagy via inhibiting Galectin-3/Akt/mTOR pathway, which synergistically ameliorated renal fibrosis. Targeting galectin-3 may be a potential target for the treatment of renal fibrosis.

• The Korean Journal of Medicine
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• v.99 no.1
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• pp.11-16
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• 2024

Myelodysplastic syndrome (MDS) is a heterogeneous disorder with diverse prognoses influenced by cytopenias, genetic variants, and myeloblast proportions in the bone marrow. Accurate prognosis prediction and tailored treatment plans are essential. The International Prognostic Scoring System-Molecular (IPSS-M), which additionally reflects the impact of MDS-related genetic mutations to the clinical and laboratory information, is anticipated to offer superior prognostic accuracy compared to existing systems like the Revised International Prognostic Scoring System (IPSS-R). Despite its statistical complexity, its web-based calculation and ease of discussing results with patients using intuitive data sets provide notable advantages. Progress in MDS treatment, exemplified by effective anemia correction with an erythropoiesis-maturation agent in SF3B1-mutated cases and efforts to refine poor prognoses in TP53-mutated cases, reflects the evolving landscape of genetic-based interventions in MDS. Advancements in genetic diagnostic technology, combined with enhanced knowledge of the bone marrow niche, are anticipated to lead to significant improvement in MDS treatment outcomes in the future.

• Journal of Acupuncture Research
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• v.23 no.1
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• pp.63-70
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• 2006

Objectives : This study was designed to evaluated the effect of electroacupuncture on Quality of life of patients with urinary incontinence Methods : Subjects were voluntarily recruited by newspapers and internet. Electroacupuncture was performed three times a week for 3 weeks. Acupuncture point for EA group was B32, Electrical stimulation frequency was 2Hz, duration 20 minutes, and intensity was up to pain threshold according to patients. The patients's symptoms were assessed before, after 3 weeks of treatment by QOL item of International Prostate Symptom Score(IPSS), Medical Outcomes Study(MOS) 36-Item Short-Form Health Survey(SF-36). Results : QOL score of IPSS were significantly improved after 3 weeks(p<0.05) compared to the pre-treatment. There were significant changes in Social functioning(SF), role-physical(RP), role emotional(RE), mental health(MH), bodily pain(BP) score of SF-36 after 3 weeks(p<0.05), but there were no significant changes in physical functioning(PF), vitality(VT), general health(GH) score of SF-36. Conclusion : This study suggests that electroacupuncture treatments can be applicable to improve symptoms in patients with urinary incontinence.

• Advances in concrete construction
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• v.6 no.4
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• pp.323-344
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• 2018

The study herein reports the impact of Steel Fiber (SF) and Ground Granulated Blast Furnaces slag (GGBFS) content on the fresh and hardened properties of fly ash (FA) based Self-Compacting Geopolymer Concrete (SCGC). Two series of self-compacting geopolymer concrete (SCGC) were formulated with a constant binder content of $450kg/m^3$ and at an alkaline-to-binder (a/b) ratio of 0.50. Fly ash (FA) was substituted with GGBFS with the replacement levels being 0%, 25%, 50%, 75%, and 100% by weight in each SCGC series. Steel fiber (SF) wasn't employed in the assembly of the initial concrete series whereas, within the second concrete series, an SF combination was achieved by a constant additional level of 1% by volume. Fresh properties of mixtures were through an experiment investigated in terms of slump flow diameter, T50 slump flow time, V-funnel flow time, and L-box height ratio. Moreover, the mechanical performance of the SCGCs was evaluated in terms of compressive strength, splitting tensile strength, and fracture toughness. Furthermore, a statistical analysis was applied in order to judge the importance of the experimental parameters, like GGBFS and SF contents. The experimental results indicated that the incorporation of SF had no vital impact on the fresh characteristics of the SCGC mixtures whereas GGBFS aggravated them. However, the incorporation of GGBFS was considerably improved the mechanical properties of SCGCs. Moreover, the incorporation of SF with the total different quantity of GGBFS replacement has considerably increased the mechanical properties of SCGCs, by close to (65%) for the splitting strength and (200%) for compressive strength.

• Journal of the Korea Concrete Institute
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• v.26 no.5
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• pp.651-660
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• 2014

Structural members using ultra high strength concrete which usually used with steel fiber is designed with guidelines based on several investigation of SF-RPC(steel fiber reinforced reactive powder concrete). However, there are not clear design method yet. Especially, SF-RPC member should be casted with steam(90 degree delicious) and members with SF-RPC usually used with precast members. Although the most important design parameter is development method between SF-RPC and steel reinforcement(rebar), there are no clear design method in the SF-RPC member design guidelines. There are many controversial problems on safety and economy. Therefore, in order to make design more optimum safe design, in this study, we investigated bond stress between steel rebar and SF-RPC according to test. Test results were compared with previously suggested analysis method. Test was carried out with direct pull out test using variables of compressive strength of concrete, concrete cover and inclusion ratio of steel fiber. According to test results, bond stress between steel rebar and SF-RPC increased with increase of compressive strength of concrete and concrete cover. Increasing rate of bond stress were decrease with increase of compressive strength of SF-RPC and concrete cover significantly. 1% volume fraction inclusion of steel fiber increase the bond stress between steel rebar and SF-RPC with two times but 2% volume fraction cannot affect the bond stress significantly. There are no exact or empirical equations for evaluation of SF-RPC bond stress. In order to make safe bond design of SF-RPC precast members, previously suggested analysis method for bond stress by Tepfers were evaluated. This method have shown good agreement with test results, especially for steel fiber reinforced RPC.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.20 no.7
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• pp.639-647
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• 2009

In this work, wrapping conductors with thin magnetic materials is proposed as a magnetic shielding method. The 0.1 mm thick metal sheets of mu-metal, grain-oriented electrical steel, and non-oriented electrical steel were produced from commercial alloy sheets through cold rolling and followed high temperature annealing. In case of 3-phase electric currents, mu-metal was the best in shielding performance at a B-field magnitude of about 100 ${\mu}T$, whereas silicon steels were better than mu-metal at a B-magnitude over 500 ${\mu}T$. In addition, wrapping with silicon steel(inner) together with mu-metal(outer) resulted in a shielding factor less than 0.1 even at 500 ${\mu}T$. These results are due to changes in hierarchy of magnetic permeabilities of the materials with increasing magnetic field strength. In case of single-phase electric current, B-magnitude outside the magnetic shell was rather increased compared to the unshielded case. This result is explained by vector composition of B-fields near magnetic shielding materials.

• Journal of The Korean Society of Grassland and Forage Science
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• v.11 no.4
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• pp.244-251
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• 1991

This study was undertaken to assess the effectiveness of magnesium-and boron-enriched complex fertilizer(CF, N-P$_2$O$_{5}$-K$_2$O-MgO-B$_2$O$_3$: 14-10-12-3-0.2) on the maintenance and management of hilly pasture. The effectiveness of CF was compared to those of some straight fertilizers (SF). This first part of the study was concerned with the soil chemical properties and the mutural balances of mineral nutrients in the soils of a mixed grass-clover and a pure grass swards. The results of a two-year field experiment are summarized as follows: 1. The Mg contents in the soils of the CF plots were higher than those of the SF plots. On the other hand, the Ca contents were higher in the SF plots than in the CF plots. The contents of Mg and Ca, and CEC, except K, in both the CF and SF plots were considerably below the optimum levels. At the normal application rate of NPK, the contents of available P$_2$O$_{5}$ were close to the optimum level in both the CF and SF plots. 2. The contents of exchangeable Mg were lower than the K contents in soils of all the plots. At the normal application rate of NPK, the Mg contents in the CF plots, but not in the SF plots, were close to the critical level for general crops (0.29me Mg/100g soil). The Mg contents in soils of all the plots, however, were considerably below the critical level for pasture forages and grazing cows (0.41me/100g). 3. Considering the desirable base saturation level of soil, the saturation levels of Ca and Mg were insufficient in both the CF and SF plots. The saturation levels of Mg in the CF plots, however, were relatively good compared with the SF plots. The equivalent ratios or Mg/K, Ca/Mg. Ca:Mg:K, and %Mg of CEC in soils were generally unfavorable in all the plots. These ratios of the CF plots, however, were relatively better than those of the SF plots. 4. Considering the contents of exchangeable Ca and Mg in soils, it is suggested that the application of slaked magnesium lime as a soil amelioration might be desirable for the fundamental increment of those contents at pasture establishment.