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Acrobeads Test를 이용한 정자수정능의 평가 (Evaluation of Sperm Fertilizing Capacity Using Acrobeads Test)

  • 박영수;박남철
    • Clinical and Experimental Reproductive Medicine
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    • 제23권1호
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    • pp.81-86
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    • 1996
  • The assessment of acrosomal status is important in evaluating the ability of sperm to fertilize the egg. The acrosomal status of sperm from 47 normal volunteers with proven fertility and 167 subfertile men with not to achieve pregnancy for at least 1 year were evaluated with Acrobeads test(FUSO Pharmaceutical Industries, Ltd, Japan) using immunobeads coated with MH61 monoclonal antibody, which is specific for acrosome-reacted sperm. The mean${\pm}$SD of acrobeads score in 47 volunteer group was $2.8{\pm}0.7$, of which 46(97.9%)cases were ${\geq}$ 2. The mean${\pm}$SD of acrobeads score in 167 subfertile group was $1.7{\pm}0.8$, of which 73(79.3%)cases were ${\leq}$ 1. The aerobe ads score in subfertile group were significantly lower(r=0.294, p<0.05) than those in volunteer group. In subfertile group, acrobeads score were well correlated with the sperm density and motility(r=0.275, r=0.281, p<0.01), but not with semen volume(r=0.16) and serum hormone level(FSH r=0.084, LH r=0.036, testosterone r=0.058, prolactin r=0.006 and estradiol r=0.060)(p>0.05). Of 63 subfertile cases with normozoospermia, 22(34.9%)cases showed 0 or 1 of acrobeads score, which means to accompany with a functional defect in spite of normal morphology. As a results, Acrobeads test is not only a technically simple sensitive procedure with good reproducibility in evaluating the sperm fertilizing capacity but also an useful in the evaluation of effectiveness in the treatment of infertility and the separation of acrosome-reacted sperm in the assisted reproductive technique.

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Nasal airway function after Le Fort I osteotomy with maxillary impaction: A prospective study using the Nasal Obstruction Symptom Evaluation scale

  • Kim, Hyo Seong;Son, Ji Hwan;Chung, Jee Hyeok;Kim, Kyung Sik;Choi, Joon;Yang, Jeong Yeol
    • Archives of Plastic Surgery
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    • 제48권1호
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    • pp.61-68
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    • 2021
  • Background This study evaluated changes in nasal airway function following Le Fort I osteotomy with maxillary impaction according to the Nasal Obstruction Symptom Evaluation (NOSE) scale. Methods This cohort study included 13 patients who underwent Le Fort I osteotomy with maxillary impaction. Nasal airway function was evaluated based on the NOSE scale preoperatively and at 3 months postoperatively. The change in the NOSE score was calculated as the preoperative score minus the postoperative score. If the normality assumptions for changes in the NOSE score were not met, a nonparametric test (the Wilcoxon signed-rank test) was used. Differences in NOSE score changes according to patient characteristics and surgical factors were evaluated using the Kruskal-Wallis test and the Mann-Whitney test. Results Patients ranged in age from 18 to 29 years (mean ±standard deviation [SD], 23.00±3.87 years). Three were men and 10 were women. Eleven patients (84%) had an acquired dentofacial deformity with skeletal class III malocclusion. The preoperative NOSE scores ranged from 40 to 90 (mean±SD, 68.92±16.68), and the postoperative NOSE scores ranged from 25 to 80 (53.84±18.83). The cohort as a whole showed significant improvement in nasal airway function following maxillary impaction (P=0.028). Eleven patients (84%) had either improved (n=8) or unchanged (n=3) postoperative NOSE scores. However, nasal airway function deteriorated in two patients. Patient characteristics and surgical factors were not correlated with preoperative or postoperative NOSE scores. Conclusions Nasal airway function as evaluated using the NOSE scale improved after maxillary impaction.

보육교사의 직무스트레스에 대한 자아탄력성과 원장.동료의 사회적 지지 (The Effect of Ego-resilience and Directors' and Fellow Teachers' Social support on Childcare Teachers' Job Stress)

  • 조성연;이정희
    • 가정과삶의질연구
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    • 제28권4호
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    • pp.29-42
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    • 2010
  • This study examined the effects of ego-resilience and directors' and fellow teachers' social support on childcare teachers' job stress. The participants were 323 childcare teachers in Chung nam Province and Daejeon Metropolitan City. The research instruments were Job Stress Scale by Cho(2004), Ego-resilience Scale by Park(1996) with CPI and CAQ correction, and Social Support Scale by Park(1985). Collected data were analysed by t-test, F test and Scheff$\acute{e}$ test for post hoc test, Pearson's productive correlation and stepwise multiple regression, and Cronbach's $\alpha$ for reliability by SPSS PC program (17.0 version). The results were as follows: First, the childcare teachers' job stress level was low (M=2.51, SD=.63), while ego-resilience level and social support level of directors and fellow teachers (M=3.68, SD=.58; M=3.62, SD=.94; M=3.83, SD=.69, respectively) were above the average. Second, there were significant differences between different levels of ego-resilience and of social support from directors and fellow teachers. Last, directors' social support and childcare teachers' optimistic attitude of ego-resilience were the most dominant variables that affected childcare teachers' job stress level(R2=38.3% for total score of childcare teachers' job stress).

간호대학생의 건강증진 행위 결정요인에 관한 연구 (Study on Health Promoting Behavior Determinant of Nursing Students)

  • 김영희;정미숙;이정애
    • 한국보건간호학회지
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    • 제16권2호
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    • pp.285-303
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    • 2002
  • This descriptive correlational study was conducted to identify the variables related to a health promoting behavior in nursing students. 238 nursing students were selected by a convenience sampling method. The data were collected by self - reported questionnaires from 12 to November 19, 2001. The data were analyzed by using descriptive statistics, pearson correlation coefficient, stepwise multiple regression with an SPSS program. The result of this study were as follows: 1. The average score of health promoting behavior was 2.47(SD=0.36)of a 4 point scale. Self actualization (mean=2.94, SD=0.50), interpersonal support (mean=2.91, SD=0.53), stress management(mean=2.58, SD=0.48), health responsibility(mean=2.07, SD=0.48)) nutrition & exercise(mean=2.07, SD=0.48)) were also analyzed. 2. Health promoting behavior showed significant positive correlations with self­esteem(r=0.446, p<0.001) perceived health status(r=0.180, p<0.01), perceived benefits (r=0.183. p<0.01). self-efficacy(r=0.311, p<0.001), social support(r=0.447, p<0.001), control(r=0.169, p<0.01). 3. The combination of self-esteem, social support, affect related to action explained $38.0\%$ of the variance in health promoting behavior. On the basis of the above findings. self-esteem and social support were identified as the variables which explained most of Pender's health promoting model. Nursing strategies enhancing self-esteem and social support which have a more significant effect on health promoting lifestyles should be developed.

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Quality of Life in Malaysian Colorectal Cancer Patients : A Preliminary Result

  • Natrah, M.S.;Ezat, Sharifa W.P.;Syed, M.A.;Rizal, A.M. Mohd;Saperi, S.
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권3호
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    • pp.957-962
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    • 2012
  • Objective: Rapidly increasing colorectal cancer (CRC) incidence in Malaysia and the introduction of cutting edge new treatments, which prolong survival, mean that treatment outcome measures meed to be evaluated, including consideration of patient's quality of life (QoL) assessment. There are limited data on QoL in CRC patients, especially in Malaysia. Therefore, this study was performed focusing on cancer stages and age groups. Methods: The cross sectional study was conducted from June to September 2011 at three public tertiary hospitals with the EORTC QLQ C-30 questionnaire in addition to face to face interview and review of medical records of 100 respondents. Results: The mean age was 57.3 (SD 11.9) years with 56.0% are males and 44.0% females, 62% of Malay ethnicity, 30% Chinese, 7% Indian and 1% Sikh. Majority were educated up to secondary level (42%) and 90% respondents had CRC stages III and IV. Mean global health status (GHS) score was 79.1 (SD 21.4). Mean scores for functional status (physical, emotional, role, cognitive, social) rangeds between 79.5 (SD 26.6) to 92.2 (SD 13.7). Mean symptom scores (fatigue, pain, nausea/vomiting, constipation, diarrhea, insomnia, dyspnoea, loss of appetite) ranged between 4.00 (SD 8.58) to 20.7 (SD 30.6). Respondents role function significantly deteriorates with increasing stage of the disease (p=0.044). Females had worse symptoms of pain (p=0.022), fatigue (p=0.031) and dyspnoea (p=0.031). Mean insomnia (p=0.006) and diarrhea (p=0.024) demonstrated significant differences between age groups. Conclusion: QOL in CRC patients in this study was comparable to that in other studies done in developed countries. Pain, fatigue and dyspnoea are worse among female CRC patients. Given that functions deteriorates with advanced stage of the disease at diagnosis, a systematic screening programme to detect cases as early as possible is essential nationwide.

40대 유방암 생존자의 우울·불안 위험요인 (Risk Factors for Depression and Anxiety among Breast Cancer Survivors in Their 40s)

  • 황숙연
    • 한국콘텐츠학회논문지
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    • 제15권2호
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    • pp.313-323
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    • 2015
  • 본 연구는 우리나라에서 가장 유방암 발생률이 높은 40대 유방암 생존자들의 우울과 불안의 정도를 파악하고 그 위험요인들을 검토하기 위해 수행되었다. 자료 수집은 유방암으로 진단 받은 40-49세 유방암 생존자 중 연구에 동의하고 설문지를 완성한 609명을 대상으로 이루어졌다. CES-D와 GAD-7을 사용하여 측정된 우울과 불안의 평균점수는 각각 16.35(SD=9.24), 4.25(SD=4.17)였으며, 절단점을 기준으로 우울군은 전체의 47.7%, 불안군은 10.3%로 나타났다. BPI-K로 측정된 통증강도 평균은 1.91(SD=1.60)이었으며, 전체의 82.8%가 통증을 호소하였고 10.9%가 중증도 이상의 통증을 보고하였다. 위계적 회귀분석결과 최종모델에서 통증 일상생활방해정도, 직업 없음, 동거가족유형과 과거 정신과 질환이 우울의 유의미한 위험요인으로 나타났고, 불안의 위험요인은 통증 일상생활방해정도, 직업 없음 및 과거 정신과질환으로 나타났다. 이러한 결과는 우리나라 40대 유방암 생존자의 우울과 불안 유병률이 높으며, 우울과 불안의 위험요인에 초점을 두어 위험군에 대한 적절한 심리사회적 개입이 제공되어야 함을 지적해주고 있다.

발달증진프로그램이 발달지연 아동 어머니의 양육 스트레스에 미치는 영향 (The Effect of the Mother-Child Development Promotion Program for the Child with Developmental Delay on Mother's Depressive Mood and Parenting Stress)

  • 유홍섭;이순정;송동호
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제20권3호
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    • pp.152-157
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    • 2009
  • Objectives : We investigated the parenting stress and depressive mood of mothers with developmentally-delayed children and the effects of participation in a mother-child development promotion program on same. Methods : Subjects were the mothers of 20 developmentally-delayed children. The severity of the mothers' parenting stress was evaluated via the Korean version of the Parenting Stress Index, Short Form (K-PSI-SF) and the severity of their depressive symptoms were evalueted by the Korean version of the Beck Depression Inventory (K-BDI). Results : The mean K-PSI-SF score and mean K-BDI score for these mothers were 93.35 (SD=10.47) and 23.25 (SD=10.42), respectively. These scores correspond to high parenting stress and moderate depression. The mothers who participated in a mother-child attachment- promotion program showed significant decreases in their K-PSI-SF and KBDI scores. Conclusion : Our data suggest that a mother-child attachment promotion program with emphasis on child development is effective in reducing parenting stress and depressive mood in mothers of developmentally-delayed children.

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폐암 환자 가족원의 스트레스와 삶의 질 (Relationship between Stress and Quality of Life of Family Caregivers of Patient with Lung Cancer)

  • 박주영
    • 종양간호연구
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    • 제10권2호
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    • pp.129-136
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    • 2010
  • Purpose: This study was conducted to examine the relationship between stress and quality of life of family caregivers of patients with lung cancer. Methods: From April 18 to May 4, 2009, data were collected using self-report questionnaires with 95 family caregivers of lung cancer patients in G cancer center. The data were analyzed using descriptive statistics, t-test, ANOVA and pearson's correlation coefficient with SPSS 14.0. Results: The mean score of the stress level was 27.5 (SD=14.77). The mean score of the QOL was 73.0 (SD=17.86). The stress level of family caregiver showed significant difference according to gender (psychological stress p=.011, total level of stress p=.042) and availableness of second caregiver (physical stress p=.023, psychological stress p=.035, total level of stress p=.001). The QOL of family caregivers showed significant difference according to daily caring (positive adaptation p=.045) and financial burden on treatment expense (positive adaptation p=.004, total quality of life p=.043). The negative correlation was found between stress and QOL of family caregivers (r=-.67, p=.032). Conclusion: These results indicate a need to develop nursing intervention programs for family caregivers to reduce stress and improve QOL.

간호사의 성역할 태도와 성건강간호 장애감 (Gender Role Attitudes and Barriers in Korean Nurses When Addressing Patients' Sexual Health)

  • 김정희
    • 기본간호학회지
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    • 제16권3호
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    • pp.282-289
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    • 2009
  • Purpose: The purpose of this research wasto examine the relationships between gender role attitudes and barriers in Korean nurses when addressing patients' sexual health. Method: The sample for this study was a convenience sample of Korean nurses who worked in hospitals in Seoul and Jeonju. Data were collected between November 2008 and January 2009. Results: Nurses showed less traditional gender role attitudes with means score of 40.72 (SD=3.99) of a possible 10 to 50 range. The barriers to addressing patients' sexual health were moderate in these nurses with a mean score of 44.92 (SD=7.66) of a possible 12 to 60 range. There were significant correlations between gender role attitudes and barriers to addressing patients' sexual health (r= -.142, p= .007). Nurses with less traditional gender role attitudes felt more barriers to addressing patients' sexual health. Conclusion: This study demonstrates a need for educational programs that will improve the problem-solving abilities of nurses in a hospital environment and help them gain ground as sexual health specialists. The results may contribute to the development and application of a patient-centered sexual health-related curriculum, which would aid nurses in addressing sexual concerns of their patients.

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Religious Coping and Quality of Life in Women with Breast Cancer

  • Zamanian, Hadi;Eftekhar-Ardebili, Hasan;Eftekhar-Ardebili, Mehrdad;Shojaeizadeh, Davood;Nedjat, Saharnaz;Taheri-Kharameh, Zahra;Daryaafzoon, Mona
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권17호
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    • pp.7721-7725
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    • 2015
  • Background: The aim of this study was to assess the predictive role of religious coping in quality of life of breast cancer patients. Materials and Methods: This multi-center cross-sectional study was conducted in Tehran, Iran, from October 2014 to May 2015. A total of 224 women with breast cancer completed measures of socio-demographic information, religious coping (brief RCOPE), and quality of life (FACT-B). Data were analyzed using descriptive statistics and the t-test, ANOVA, and linear regression analysis. Results: The mean age was 47.1 (SD=9.07) years and the majority were married (81.3%). The mean score for positive religious coping was 22.98 (SD=4.09) while it was 10.13 (SD=3.90) for negative religious coping. Multiple linear regression showed positive and negative religious coping as predictor variables explained a significant amount of variance in overall QOL score ($R^2=.22$, P=.001) after controlling for socio-demographic, and clinical variables. Positive religious coping was associated with improved QOL (${\beta}=0.29$; p=0.001). In contrast, negative religious coping was significantly associated with worse QOL (${\beta}=-0.26$; p=0.005). Conclusions: The results indicated the used types of religious coping strategies are related to better or poorer QOL and highlight the importance of religious support in breast cancer care.