• Title/Summary/Keyword: SCREEN TEST

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Differentially Expressed Genes in Marine Medaka Fish (Oryzias javanicus) Exposed to Cadmium

  • Woo, Seon-Ock;Son, Sung-Hee;Park, Hong-Seog;Vulpe, Chris D.;Ryu, Jae-Chun;Yum, Seung-Shic
    • Molecular & Cellular Toxicology
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    • v.4 no.4
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    • pp.293-299
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    • 2008
  • To screen the differentially expressed genes in cadmuim-exposed marine medaka fish (Oryzias javanicus), a candidate marine test fish for ecological toxicity, the differential display polymerase chain reaction (DD-PCR) was carried out, since the genome-wide gene expression data are not available in this fish species yet. A total of 35 clones were isolated from cadmium-exposed fish and their nucleotide sequences were analyzed. The differentially expressed gene candidates were categorized to response to stimulus (3); ion binding (3); DNA binding (1); protein binding (6); carbohydrate binding (1); metabolic process (4); biological regulation (3); cellular process (2); protein synthesis (2); catalytic activity (2); sense of sight (1); immune (1); neurohormone (1); signaling activity (1); electron carrier activity (1) and others (3). For real-time quantitative RT-PCR, we selected catalase, glucose-6-phosphate dehydrogenase, heat shock protein 70, and metallothionein and confirmed that cadmium exposure enhanced induction of these four genes.

Effects of Ukgansan (Yokukansan in Japanese, Yigansan in chinese) on the Locomotor Velocity and Glutamate-Induce Paroxysm in Planarian (Planarian 모델을 이용한 억간산의 항발작 효과)

  • Park, Woong;Yoo, Du Man;So, June No
    • KSBB Journal
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    • v.29 no.1
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    • pp.67-71
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    • 2014
  • Planaria were recently reported to be a simple and sensitive model to investigate the mechanistic aspect of seizure and to screen potential anticonvulsants. Using planarian model, we analyzed the pharmacological effect of ukgansan (UGS), an oriental herbal medicine containing seven medicinal herbs, on the planarian locomotor velocity (pLMV) and glutamate-induced seizure-like activity (pSLA). To test whether D. japonica is suitable for studying anti-seizure agents, we investigated the effect of glutamate on pLMV and pSLA in D. japonica. In the present study we first confirmed that pSLA in D. japonica was induced by L-glutamate. Glutamate significantly produced pSLA in a dose dependent manner, but did not affect pLMV. These glutamate-induced paroxysms were decreased by antiepileptic drug, topiramate. A similar inhibitory effect on glutamate-induced pSLA was observed after the treatment of UGS. The present results suggest that UGS and its active constituents possess useful substance inhibiting seizure in planarian and that D. japonica provides a convenient model to search active herbs containing anti-seizure activity.

Design and Implement of Smart Phone Tour Game using A-GPS (A-GPS를 이용한 스마트폰 투어게임 설계 및 구현)

  • Kim, Hyeong-Gyun;Bae, Yong-Guen;Go, Mi-A
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.6
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    • pp.111-118
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    • 2011
  • This paper proposed a smart phone tour game using A-GPS. This game is a fused content of tourism and education. This game is based on the historical background of Silla and spatial background of GyoengJu. Game event has occurred by comparing pre-measured GPS values and smart phone A-GPS values. The field test of event were used to correct the A-GPS error by 3 times. This paper has looked at game planning and run screen. In addition, the future direction of the game were discussed.

Optimum Global Failure Prediction Model of Inconel 600 Thin Plate with Two Parallel Through-Wall Cracks

  • Moon Seong In;Kim Young Jin;Lee Jin Ho;Song Myung Ho;Choi Young Hwan
    • Nuclear Engineering and Technology
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    • v.36 no.4
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    • pp.316-326
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    • 2004
  • The $40\%$ of wall criterion, which is generally used for the plugging of steam generator tubes, is applied only to a single crack. In a previous study, a total number of 9 failure models were proposed to estimate the local failure of the ligament between cracks, and the optimum coalescence model of multiple collinear cracks was determined among these models. It is, however known that parallel axial cracks are more frequently detected than collinear axial cracks during an in-service inspection. The objective of this study is to determine the plastic collapse model that can be applied to steam generator tubes containing two parallel axial through-wall cracks. Three previously proposed local failure models were selected as the candidates. Subsequently, the interaction effects between two adjacent cracks were evaluated to screen them. Plastic collapse tests for the plate with two parallel through-wall cracks and finite element analyses were performed to determine the optimum plastic collapse model. By comparing the test results with the prediction results obtained from the candidate models, a COD base model was selected as an optimum model.

An Experimental Study on the Operational Characteristics and Performance of the Sodium Heat Pipe (나트륨 히트파이프의 작동 특성 및 성능에 관한 실험적 연구)

  • Kang, Hwan-Kook;Lee, Dong-Chan;Park, Sang-Woon;Song, Jee-Hyuk;Yoo, Jung-Hyun
    • Proceedings of the SAREK Conference
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    • 2005.11a
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    • pp.311-316
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    • 2005
  • The experimental study for an operational characteristics and performance of the sodium heat pipe were carried out. For an experiment. the heat pipe which is 1000mm length and 25.4mm diameter of stainless steel container with 50 mesh of screen wick using sodium as a working fluid is manufactured and tested as functions of heat flow rate, inclined angle and operating temperature. The test results are as follows. During the start-up. frontal start up was observed because of the vapor density increasing as increased the hot zone. Also, the heat pipe showed uniform temperature over than $420^{\circ}C$ of the operating temperature. The average heat transfer coefficient increased as the heat flux and the vapor temperature increase, and the range of the total thermal resistance was 0.075-0.04 $^{\circ}C/W$ at the 12-53.55 $kW/m^2$ of heat flux and $500-750^{\circ}C$of operating temperature. The maximum heat flow rate was 750W at the 10 degree of top heating mode.

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Factors Affecting Consumer Goods Buyers' Choice in E-Commerce Sites: Evidence from Vietnam

  • PHAM, Hung Cuong
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.11
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    • pp.947-953
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    • 2020
  • The main purpose of this study is to find the factors affecting the consumer goods buyers' choice on e-commerce sites in Vietnam. By using the quantitative method, the paper examines the theoretical research model and tests four hypotheses. The sample was drawn from the population of e-commerce sites in Vietnam comprising about 1,000 respondents. This study used the questionnaire method to collect primary data to test the hypotheses. Data analysis of the questionnaire was done using SPSS. The results show that there is a correlation between personal preferences of consumers on colors and brands and their actual final choice on e-commerce sites in Vietnam. The most important factor affecting the consumer goods buyers' choice on e-commerce in Vietnam is the brand of E-commerce site, following by the color and position. Among all educational groups, respondents with a Master degree pay the biggest attention to the site's color attribute, and those with a Bachelor degree pay more attention to the brand attribute. Women pay much more attention to the location of the products on the screen than men, as do consumers with a PhD degree, over respondents with a Bachelor or Master degree, and foreigners over Vietnamese consumers.

Developing the Measurement System with Establishing the PHY Performance of Best Proper Cable Modem (최적의 케이블 모뎀 PHY 성능 구현 및 케이블 망 측정 시스템 개발)

  • Lee, Kyoung-Moon;Ko, Jae-Pyung;Lee, Jang-Myung
    • Journal of Institute of Control, Robotics and Systems
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    • v.14 no.2
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    • pp.205-211
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    • 2008
  • This paper describes the method aimed at establishing the equipment measuring the parameter of Cable Network by Best proper Cable Modem and PDA through RS232 interface. In this paper, we propose our creative experimental configuration and develope the Cable Modem (DOCSIS 2.0) superior more performing than the referred Cable Modem (DOCSIS 1.0, 1.1) and the measuring equipment of HFC network compositing of Cable Modem and PDA through RS232 interface. This equipment analyzes Upstream (U/S) and Downstream (D/S) Signal quality and generates the signal of Upstream by CW signal. The paper also provides the experimental results to check the Best Proper Cable Modem and the displayed screen for parameters for SNR, BER and the demodulated IQ diagram of 256QAM through LCD of PDA. Henceforth, it'll be possible to support a variety of the functions for E-mail, Internet, the speed test of WEB connection and the transmission of the measured result real time by PDA.

Elimination of Discontinuity Phenomenon for Repeated Play of Finite DTV Stream (유한 DTV 스트림의 반복 재생시 불연속 현상 제거)

  • Han, Chan-Ho;Sohng, Kyu-Ik
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.27 no.10A
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    • pp.951-961
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    • 2002
  • In general, there is discontinuity phenomenon like a black screen and an irregular sound for repeated play of a finite digital stream. In this paper, for repeated play we analyze the relation between source and stream time causes this phenomenon. We obtain the time relation between video frame rate, audio frame rate, and TS packet transmission rate to eliminate this phenomenon. Using this time relation, we propose a new generation method of elementary stream (ES) and transport stream (TS) to eliminate discontinuity phenomenon. The test results of the generate ES and TS using the proposed method show that the discontinuity phenomenon can be eliminated for repeated play of a finite proposed stream.

A Study in the Water Leakage Prevention around the Windows with the Stone Materials in the Apartment House (공동주택 외부 석재마감에 따른 창호주위 누수방지에 관한 연구)

  • Yun, Hong-Jung;Cho, Tae-Jea
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2006.11a
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    • pp.117-121
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    • 2006
  • This study intends to suggest the effective methods for water leakage prevention around the windows in stone works to up-grade the outdoor public space that has been taken much portion of apartment housing trends. The subjects of the study was selected among the domestic subcontractors of stone works. There are four methods for water leakage prevention around the windows; Firstly, the painting water-proof method after the masonry. Secondly, the urethane water-proof method after galvanizing panels on the gap. Thirdly, the separation method between stone and substructure and the last one is water-proof method that they put some water-proof screen between stone and substructure with the EPDM sheets. According to the analysis of the water-proof effects, constructability and planning, we could approach to conclusion that the most influent items to the water-leakage are the filling material's deformation, the state of oxygenation and deterioration of work skill. Among the water-proof methods in construction the EPDM sheet is most excellent water-proof method to meet the technical conditions. However, we have to apply it to stone works as a water-proof method for the decrease of the leakage defects after standardizing the materials, test and construction skill because there are many work skills according the subcontractors.

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The Effects of Stress, Social Support and Impulsiveness on Adolescents' Internet Addiction (청소년의 스트레스, 사회적 지지 및 충동성이 인터넷 중독에 미치는 영향)

  • Park, Gi-Eun;Choi, Yeon-Hee
    • The Korean Journal of Rehabilitation Nursing
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    • v.14 no.2
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    • pp.145-152
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    • 2011
  • Purpose: The study was to identify the influences of stress, social support and impulsiveness on the internet addiction of adolescents. Methods: A cross-sectional study was conducted with 243 male middle and high school students in D city. Data were collected from March to April in 2009 using self-report questionnaires such as internet addiction test, perceived stress, social support appraisal scale and Barratt impulsiveness scale. Data were analyzed using frequency, mean, Pearson's corelation coefficient, & hierarchial multiple regression. Results: The results showed that adolescents who had poor social support or higher stress and impulsiveness were more likely to have higher levels of internet addiction. The internet addiction was positively related to the stress and impulsiveness and negatively related to the social support. And education, record at school, stress, social support and impulsiveness had influence on the depression. Conclusion: Based on the findings, school nurses need to screen the risk of the internet addiction for adolescents who are in serious stress and have poor social support and impulsiveness. It is necessary to develop some preventive programs for those in high risk of internet addiction.