• Proceedings of the Korea Information Processing Society Conference
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• 2012.04a
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• pp.1215-1218
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• 2012

본 논문에서는 국내외 선진회사의 SCL 엔지니어링 툴에 관한 연구를 진행하였다. 최근 전력산업이 디지털화 되면서, 변전소자동화에 관련된 국제 표준인 IEC61850은 필수 요소로 자리 잡았다. 따라서 IEC61850 표준에서 사용하는 SCL파일들을 생성, 수정하고, 각종 서비스들을 규정하는 SCL 엔지니어링 작업은 필수적이다. 하지만, 현재 벤더중심, 해외위주의 엔지니어링 툴만이 대부분이기 때문에 국내 실정에 맞는 디지털변전소 엔지니어링 툴을 개발하는 것이 시급하다. 따라서 본 연구는 여러 가지 관점에서 선진 툴들을 분석하고, 분석내용을 토대로 SCL 엔지니어링 툴의 필수 기능들을 도출하고, 사용자 중심의 편의성 높은 엔지니어링 툴을 설계하는 것을 목표로 한다.

• Radiation Oncology Journal
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• v.25 no.2
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• pp.109-117
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• 2007

[ $\underline{Purpose}$ ]: To evaluate the incidences and potential predictive factors for symptomatic radiation pneumonitis (SRP) and radiographic pulmonary toxicity (RPT) following adjuvant radiotherapy (RT) for patients with breast cancer. A particular focus was made to correlate RPT with the dose volume histogram (DVH) parameters based on three-dimensional RT planning (3D-RTP) data. $\underline{Materials\;and\;Methods}$: From September 2003 through February 2006, 171 patients with breast cancer were treated with adjuvant RT following breast surgery. A radiation dose of 50.4 Gy was delivered with tangential photon fields on the whole breast or chest wall. A single anterior oblique photon field for supraclavicular (SCL) nodes was added if indicated. Serial follow-up chest radiographs were reviewed by a chest radiologist. Radiation Therapy Oncology Group (RTOG) toxicity criteria were used for grading SRP and a modified World Health Organization (WHO) grading system was used to evaluate RPT. The overall percentage of the ipsilateral lung volume that received ${\geq}15\;Gy\;(V_{15}),\;20\;Gy\;(V_{20})$, and $30\;Gy\;(V_{30})$ and the mean lung dose (MLD) were calculated. We divided the ipsilateral lung into two territories, and defined separate DVH parameters, i.e., $V_{15\;TNGT},\;V_{20\;TNGT},\;V_{30\;TNGT},\;MLD_{TNGT}$, and $V_{15\;SCL},\;V_{20\;SCL},\;V_{30SCL},\;MLD_{SCL}$ to assess the relationship between these parameters and RPT. $\underline{Results}$: Four patients (2.1%) developed SRP (three with grade 3 and one with grade 2, respectively). There was no significant association of SRP with clinical parameters such as, age, pre-existing lung disease, smoking, chemotherapy, hormonal therapy and regional RT. When 137 patients treated with 3D-RTP were evaluated, 13.9% developed RPT in the tangent (TNGT) territory and 49.2% of 59 patients with regional RT developed RPT in the SCL territory. Regional RT (p<0.001) and age (p=0.039) was significantly correlated with RPT. All DVH parameters except for $V_{15\;TNGT}$ showed a significant correlation with RPT (p<0.05). $MLD_{TNGT}$ was a better predictor for RPT for the TNGT territory than $V_{15\;SCL}$ for the SCL territory. $\underline{Conclusion}$: The incidence of SRP was acceptable with the RT technique that was used. Age and regional RT were significant factors to predict RPT. The DVH parameter was good predictor for RPT for the SCL territory while $MLD_{TNGT}$ was a better predictor for RPT for the TNGT territory.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.2
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• pp.27-30
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• 2009

Purpose: Transmittance at UV-visible spectra range was measured to confirm the effect of wet/dry state of commercially available SCL on human eyes. Method: Commercially available five SCLs fabricated by different materials were selected to measure optical properties according to humidity. Results: A relatively high transmittance above about 80% in the visible spectra range of the SCLs were observed. In the UV spectra range, the wet samples showed higher transmittance than those dried except an unusual case. Conclusions: All the samples having a high optical properties in the visible spectra range exhibit a high transmittance in the UV region. Further research will be needed to develop new materials having a sharp absorption edge in the UV spectra range.

• Microbiology and Biotechnology Letters
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• v.48 no.4
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• pp.429-438
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• 2020

The emergence of multi-drug resistant, pathogenic methicillin-resistant Staphylococcus aureus (MRSA) is a threat to global health and has created a need for novel functional therapeutic agents. In this study, we evaluated the underlying mechanisms of the anti-MRSA effect of an azaphilone pigment, sclerotiorin (SCL) from Penicillium sclerotiorum. The antimicrobial activity of SCL was evaluated using agar disc diffusion, broth microdilution, time-kill assays and biophysical studies. SCL exhibits selective activity against Gram positive bacteria including MRSA (range, MIC = 128-1028 ㎍/ml) and exhibited rapid bactericidal action against MRSA with a > 4 log reduction in colony forming units within three hours of administration. Biophysical studies, using fluorescent probes and laser or electron microscopy, demonstrated a SCL dose-dependent alternation in membrane potential (62.6 ± 5.0.4% inhibition) and integrity (> 95 ± 2.3%), and the release of UV260 absorbing materials within 60 min (up to 3.2 fold increase, p < 0.01) of exposure. Further, SCL localized to the cytoplasm and hydrolyzed plasmid DNA. While in vitro checkerboard studies revealed that SCL potentiated the antimicrobial activity of topical antimicrobials such as polymixin, neomycin, and bacitracin (Fractional Inhibitory Concentration Index range, 0.26-0.37). Taken together these results suggest that SCL targets the membrane and DNA of MRSA to facilitate its anti-MRSA antimicrobial effect.

• Korean Journal of Psychosomatic Medicine
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• v.10 no.1
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• pp.37-47
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• 2002

Objective : Previous studies have suggested an association between sleep-related breathing disorder (SRBD) and several psychological problems, and there were increasing recognition of the link. The purpose of this study is to evaluate the characteristic profiles of MMPI and SCL-90-R in patients with SRBD. Methods : This study consisted of 80 SRBD patients(73 men, 7 women) referred from Sleep Disorder Clinic of Dong-A University Hospital, Busan, Korea. Basic informations including demographic findings and physical examination were collected. Subjects completed the Epworth Sleepiness Scale(ESS), Minnesota Multiphasic Personality Inventory(MMPI), and Symptom Check List-90-Revision (SCL-90-R) prior to standard overnight polysomnography that was performed at hospital sleep laboratory. SRBD was divided into two groups of primary snoring(PS) and obstructive sleep apnea(OSA) according to polysomnographic findings. Results : SRBD showed significant elevation rate of Hs, D, and Hy scales of MMPI and SOM scale of SCL-90-R, which exceeded the rate expected in normal individuals(>5%, 2SD). On comparison of clinical scales of SCL-90-R, OSA group had significantly greater mean score than that of PS group in terms of O-C, DEP, PAR, GSI(p<0.05), SOM and PST(p<0.01). OSA group also showed significantly higher elevation rate in Hs scale of MMPI and SOM scale of SCL-90-R than that of PS. Among OSA group, three scales of MMPI(D, Pt, Si) and three scales of SCL-90-R(ANX, PAR, PSDI) had significant correlation with some PSG variables including total sleep time and sleep efficiency. Among PS group, two scales of MMPI(Hy and Pt), elevation rate of MMPI scales and three scales of SCL-90-R(I-S, PAR, PSDI) had significant correlation with some PSG variables including sleep efficiency, sleep latency and REM sleep percent. Conclusion : The above results suggest that SRBD show neurotic profiles in MMPI and SCL-90-R. This study also clearly indicates that PS group are suffered from clinically meaningful psychiatric symptoms, which are quantitatively lessened but qualitatively similar as compared to that of OSA group.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.4
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• pp.375-381
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• 2011

Purpose: The purpose of this research was to see how wearing either a SCL or a C-SCL effected the dryness of a person's eye depending on how long they wear either type of lens. Methods: This study was carried out on 52 subjects (104 eyes) who were all in their twenties and had previously experienced wearing contact lenses. All of these subjects were required to wear either a SCL or a C-SCL, which were made out of the same material, for three months. Contents such as the McMonnies Questionnaire survey, the blinking rate per min. and the Noninvasive tear break-up time test (NIBUT) were later conducted on the subjects for this study. Results: According to the results of the McMonnies Questionnaire, it was concluded that the longer the subject wore the SCL and C-SCL, the value of the measurements gradually increased. On the other hand, the results from the NIBUT concluded that the longer the subject wore the SCL, the value of the measurements eventually decreased. However, according to the measurements of the blink rate test, it was concluded that neither results had a significant change. Conclusions: It was concluded that long-term wearing of SCL and C-SCL could be the cause of the induction and progression of dry eyes.

• Journal of Oriental Neuropsychiatry
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• v.14 no.1
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• pp.117-131
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• 2003

SCL-90-R is a multidimensional self-report symptom inventory devoloped by Derogatis and his coworkers. Since it was standardized into Korean version in 1978 by Won and Kim et aI., but it has been rarely studies for the clinical groups. Objectives : This study sought to define a diagnotic character of SCL-90-R of tension headache and insomnia inpatients groups. Methods : We determined a diagnotic character of 17 tension headache and 23 insomnia patients by means of SCL-90-R, and compared with normal groups in order to characterize subscale of SCL-90-R in patients with tension headache and insomnia from Neurasthenia. Results : 1. Male tension headache group has significant difference in Somatization and Depression subscales, female group in Somatization, Obsessive-Compulsive, Depression and Hostility subscales. 2. Female insomnia group has significant difference in Anxiety subscale. Although there are a little significiant, many subscales such as Somatization, Obsessive-Compulsive, Depression and Hostility are higher than normal group. 3. There are significant difference in GSI and PDSI of Global index, which means that we use that for objective index of tension headache and insomnia from Neurasthenia. Conclusions : All of these results show that SCL-90-R is useful inventory to characterize and screening for Neurasthenia.

• Journal of Microbiology and Biotechnology
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• v.19 no.11
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• pp.1439-1446
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• 2009

Isocarbophos is a widely used organophosphorus insecticide that has caused environmental pollution in many areas. However, degradation of isocarbophos by pure cultures has not been extensively studied, and the degradation pathway has not been determined. In this paper, a highly effective isocarbophos-degrading strain, scl-2, was isolated from isocarbophos-polluted soil. The strain scl-2 was preliminarily identified as Arthrobacter sp. based on its morphological, physiological, and biochemical properties, as well as 16S rDNA analysis. The strain scl-2 could utilize isocarbophos as its sole source of carbon and phosphorus for growth. One hundred mg/l isocarbophos could be degraded to a non detectable level in 18 h by scl-2 in cell culture, and isofenphos-methyl, profenofos, and phosmet could also be degraded. During the degradation of isocarbophos, the metabolites isopropyl salicylate, salicylate, and gentisate were detected and identified based on MS/MS analysis and their retention times in HPLC. Transformation of gentisate to pyruvate and fumarate via maleylpyruvate and fumarylpyruvate was detected by assaying for the activities of gentisate 1,2-dioxygenase (GDO) and maleylpyruvate isomerase. Therefore, we have identified the degradation pathway of isocarbophos in Arthrobacter sp. scl-2 for the first time. This study highlights an important potential use of the strain scl-2 for the cleanup of environmental contamination by isocarbophos and presents a mechanism of isocarbophos metabolism.

• Proceedings of the Zoological Society Korea Conference
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• 1996.10a
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• pp.243.2-243
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• 1996

No Abstract, See Full Text

• Proceedings of the Zoological Society Korea Conference
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• 1996.10a
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• pp.253.2-253
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• 1996

No Abstract, See Full Text