• Title/Summary/Keyword: SCI

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Antioxidant and Neuronal Cell Protective Effect of Purple Sweet Potato Extract (자색고구마 추출물의 항산화 효과 및 신경세포 보호효과)

  • Kwak, Ji-Hyun;Choi, Gwi-Nam;Park, Ju-Hee;Kim, Ji-Hye;Jeong, Hee-Rok;Jeong, Chang-Ho;Heo, Ho-Jin
    • Journal of agriculture & life science
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    • v.44 no.2
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    • pp.57-66
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    • 2010
  • The antioxidant and neuronal cell protective effects of water extract from purple sweet potato were investigated. The total phenolics and monomeric anthocyanin contents of purple sweet potato extract were 44.25 mg/g and 2,394 mg/L, respectively. The antioxidant activities of purple sweet potato extract were evaluated using various antioxidant tests, including 1,1-diphenyl- 2-picrylhydrazyl (DPPH), 2,2'-azino- bis-(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging activities, ferric reducing/antioxidant power (FRAP) and reducing power. In these assays, the extract of purple sweet potato presented significant radical scavenging activities, FRAP, and reducing power in a dose-dependent manner. MTT {3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyl- tetrazoliumbromide} reduction assay showed significantly increase in cell viability when PC12 cells were pretreated with purple sweet potato extract. Because oxidative stress is also known to increase neuronal cell membrane breakdown, we further investigated by lactate dehydrogenase (LDH) and neutral red uptake assay. Purple sweet potato extract inhibited oxidative stress-induced membrane damage in neuronal cells. Therefore, these data results demonstrated that water extract of purple sweet potato have antioxidant activity and neuronal cell protective effect thus it has great potential as a natural source for human health.

A Study on the Expression Style of the Sci-Fi Movie Set Design (SF 영화 세트 디자인의 표현 유형에 관한 연구)

  • 김태은;김주연
    • Korean Institute of Interior Design Journal
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    • no.33
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    • pp.122-128
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    • 2002
  • In the Sci-Fi movie, with future scene in its setting, how images are shown in the film is very important. Sci-Fi movie is supposed to be expressed In different way of its set design. This study suggests various types of expression in Sci-Fi movies. Sci-Fi movies construct the narrative upon the binary opposition of nature vs. culture, human vs. nonhuman. Sci-Fi movie is a contested terrain where conservative, liberal and radical ideologies are competing. While liberal Sci-Fi movies consider the opposition compatible, conservative texts show the paranoid towards science and nonhumans. And, Sci-Fi movies are expressed as utopian and dystopian. Utopian and dystopian elements are found in the history of architecture. Utopian element is often found in the religious architecture, and those buildings are geometric, orderly, and gorgeous. Dystopian element is often found in modern architecture, and those are asymmetric, distorted, and incompleted. Conservative movie, which developing of science is expressed negatively, retains both utopian and dystopian elements evenly. Liberal movie, such as Space Opera which science is expressed positively, is changed from futurist and mechanical type into more simple, geometric and orderly shrine type. Radical movie, which the boundary of human and science is expressed darkly, retains dark, complex, and incomplete dystopian expression elements.

The Effects of Pulsed Electromagnetic Field on Functional Recovery and Expression of GAP-43 after Incomplete Spinal Cord Injury in Rats (맥동전자장이 불완전 척수손상 흰쥐의 기능회복과 GAP-43의 발현에 미치는 영향)

  • Bang, Hyun-Soo
    • Journal of the Korean Society of Physical Medicine
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    • v.7 no.3
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    • pp.349-356
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    • 2012
  • Purpose : This study was designed to investigate the effects of pulsed electromagnetic field on functional recovery and expression of GAP-43 after incomplete spinal cord injury (SCI) in rats. Methods : To confirm the damage of SCI and effects of pulsed electromagnetic field, 20 Sprague-Dawley male rats were used and divided randomly 2groups (SCI, PEMF). Incomplete SCI was induced by using modified NYU drop model. After operation, functional recovery test, immunohistochemistry and western blot analysis were measured at 1, 2, 3 weeks. Pulsed electromagnetic field were apply three weeks (one times a day, five days a week and twenty minutes a session). Results : In the this study, applications of pulsed electromagnetic field after incomplete SCI induced the significant improvement in functional recovery and expression of neurotrophic factor. The results were as follows; Foot print test, PEMF were significantly decreased than the SCI (p<.05). Expression of GAP-43, PEMF were significantly increased than the SCI at 2 and 3 weeks (p<.05). Conclusion : In conclusion, pulsed electromagnetic field were positive effect in functional recovery and expression of GAP-43 after incomplete SCI in rats.

The quality of Reports on Randomized Controlled Trials abstracts from Korean Science Citation Index journal and NEJM; Evaluation and Comparison of adherence to the CONSORT Statement (CONSORT statement를 기반으로 한 국내 Science Citation Index 저널과 NEJM의 Randomized Controlled Trial의 abstracts 질적 비교 평가 연구)

  • Kyung, Eun-Jung;Kim, Hyo-Seon;Kim, Eun-Young
    • Korean Journal of Clinical Pharmacy
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    • v.22 no.2
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    • pp.131-136
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    • 2012
  • Objective: This study evaluated and compared the adherence to the CONSORT for quality of reports on the randomized controlled trials (RCT) abstracts by four major Korean Science Citation Index (SCI) journals and The New England Journal of Medicine (NEJM). Methods: A descriptive analysis of published RCT abstracts in Korean SCI journals and NEJM from 2007/01 to 2011/06 was conducted by two reviewers, independently extracting data from a PubMed search. A modification of CONSORT for abstract was used including 16 checklist items. Reporting of checklist items for individual group was conducted to compare adherence patterns between two groups. Results: We identified the potential 57 RCT abstracts from Korean SCI and 50 from NEJM meeting our inclusion criteria; among them, three abstracts from Korean SCI and one from NEJM were excluded. Among total 16 checklist items based on CONSORT statement, Korean SCI journals and NEJM were statistically equivalent in 4 items; Korean journals were better in three items and NEJM were in nine. The methodological quality domains were inadequately reported in both journals: allocation concealment about 1.9% and 4.0%, and blinding 44.4% and 40.8%. In general, The CONSORT adherence of NEJM was better than that of Korean SCI in the method and result domain (p < 0.0001). Conclusions: The quality of NEJM reporting of RCT abstracts was better than that of Korean SCI, in general. This study on adherence of RCT reports from Korean SCI journals and NEJM abstracts to the CONSORT statement reveals that there is a need for improvement, especially Korean SCI. Further investigation on the quality of RCT reports and ways to improve reporting quality is required.

Effects of growing degree days on growth and yield of maize depending on the sowing date

  • Jung, Gun Ho;Kim, Mi Jung;Son, Beom Young;Shin, Seong Hyu;Kim, Sung Kook;Lee, Jae Eun;Kim, Chung Guk;Kwon, Young Up;Shim, Kang Bo;Heu, Sunggi
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.324-324
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    • 2017
  • Total 15 different corn hybrids, Kwangpyeongok, Gangdaok, Yanganok, Singwangok, Jangdaok, Cheonganok, Cheongdaok, Andaok, Dapyeongok, Pyeongkangok, Pyeonganok, Daanok, Sunwon P3394, Gangilok, P3394, had been used to investigate the plant growth and yield of corn hybrids depends on the sowing date. Sowing dates were April 5th, June 25th, and July 5th and all experiments had three repeats. The growth of Gangdaok was the best. However, in the case of Kwangpyeongok, the growth was not the best to compare with Gangdaok, but the stem to ear height ratio was lower than Gangdaok, it may be better for the stable cultivation. Both of the growth and yield of Daanok was not good regardless of planting date, but the yield and ear shape of Pyeongkangok and Dapyeongok were good for fresh corn. The growth and yield of 15 different corn hybrids were variable depends on the planting date, however, the growth degree days (GDD) was the most important factor for the maturity of the corn. More than $1500^{\circ}C$ of GDD was enough to harvest mature corn hybrids in the central region of Korea. Besides the yield and growth, other characters such as sweetness and taste as a food should be investigated further for the fresh corn to be suggested.

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Current status on the development of GM plants based on the published articles and patents in Korea (논문 및 특허의 분석을 통한 국내 GM식물의 개발 현황)

  • Lee, Shin-Woo
    • Journal of Plant Biotechnology
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    • v.37 no.4
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    • pp.394-399
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    • 2010
  • During the last three years (2007 to 2009), 1,212 articles of SCI journals, 451 articles of non-SCI journals, and 348 items of registered patents were reported by the research scientists involved in the BioGreen 21 Project, Rural Development Administration and Crop Functional Genomics Center (CFGC), The 21st century Frontier Program, in Korea. Out of these, the percentages of articles or patents directly related to the development of GM plants were 6.0% (SCI), 10.2% (non-SCI) and 12.6% (patents) from BioGreen 21 Project while 15.7% (SCI), 21.1% (non-SCI) and 81.6% (patents) from CFGC, respectively. It was observed that rice and pepper were major host crops for genetic modification mainly to provide the resistance or tolerance activities against to biotic as well as abiotic stresses. Very low cases were reported for the field test of GM plants regarding to the commercialization (less than 15 articles). These observations indicates that more research grants needs to be invested for the risk assessment of GM plants under early developmental stage to commercialize in Korea.