• Composites Research
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• v.34 no.6
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• pp.412-420
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• 2021

In this study, we measure the initial electrical conductivity of SCF/rubber specimens and SCF/rubber specimens with nickel particles respectively. The corresponding electrical conductivity with compressive strain on the specimens is also measured. Through this experiment, we observed the effects of the volume fraction of carbon fiber, nickel particles and external strain on the electrical conductivity. Experiments show that even a small difference in the volume fraction of SCF plays a major role in the change of the electrical conductivity and that the piezoresistivity increases due to fiber reorientation respond to external strain. In addition, the nickel particles contribute to improving the electrical conductivity in specimens with carbon fibers above the threshold volume fraction. It was confirmed that there is an effect of offsetting the increment in the piezoresistivity caused by the reorientation of carbon fibers according to external strain.

• Journal of Microbiology and Biotechnology
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• v.34 no.2
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• pp.367-378
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• 2024

In this study we sought to elucidate the therapeutic effects of fenchone on constipation-predominant irritable bowel syndrome (IBS-C) and the underlying mechanisms. An IBS-C model was established in rats by administration of ice water by gavage for 14 days. Fenchone increased the reduced body weight, number of fecal pellets, fecal moisture, and intestinal transit rate, and decreased the enhanced visceral hypersensitivity in the rat model of IBS-C. In addition, fenchone increased the serum content of excitatory neurotransmitters and decreased the serum content of inhibitory neurotransmitters in the IBS-C rat model. Meanwhile, western blot and immunofluorescence experiments indicated that fenchone increased the expressions of SCF and c-Kit. Furthermore, compared with the IBS-C model group, fenchone increased the relative abundance of Lactobacillus, Blautia, Allobaculum, Subdoligranulum, and Ruminococcaceae_UCG-008, and reduced the relative abundance of Bacteroides, Enterococcus, Alistipes, and Escherichia-Shigella on the genus level. Overall, fenchone ameliorates IBS-C via modulation of the SCF/c-Kit pathway and gut microbiota, and could therefore serve as a novel drug candidate against IBS-C.

• Journal of the Korean Ceramic Society
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• v.41 no.6
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• pp.481-484
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• 2004

TiO$_2$ and TiO$_2$-CdS powders which were expected to be highly activated photocatalysts were prepared using supercritical fluid method (SCF). The prepared photocatalyst TiO$_2$ powders were crystalline of anatase and ultrafine spherical powders with large specific surface area. When photodecompositoion reaction was done with TiO$_2$ powders prepared by SCF as a photocatalyst in DCA (Dichloroactic Acid) solution, a hazardous organic compound, the photocatlyst, properties of TiO$_2$ powders prepared by SCF were better than that of commercial TiO$_2$ powders.

• Journal of the Korean Chemical Society
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• v.19 no.4
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• pp.218-224
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• 1975

The ground state SCF IMO theory was applied to the Diels-Alder reactions of cyclopentadiene with 2-substituted acrylonitriles. The CNDO/2 MO of the separate systems, including both $\sigma$ and $\pi$ electrons, was used as starting point. The qualitative prediction of the relative reactivity was made with the calculated primary interaction energies. Here the calculated activation energies appeared to be realistic. The stereoselectivity determined by the calculated secondary interaction energies represented the endo-selectivity for all the substituents. The reason for the slightly unsymmetrical ring closure at the transition state was discussed in terms of valence inactive electron densities of the reacting atoms.

• International Journal of Industrial Entomology and Biomaterials
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• v.21 no.2
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• pp.151-155
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• 2010

Protein disulfide isomerase (PDI) catalyzes the oxidation of disulfides and the isomerizatiob of incorrect disulfides in new polypeptides during folding in the oxidizing environment of the endoplasmic reticulum (ER). To increase recombinant protein hSCF (human stem cell factor) production, we have developed expression system using the Bombyx mori PDI (bPDI) as a fusion partner. bPDI gene fusion was found to improve the production of recombinant hSCFs. Thus, we conclude that bPDI gene fusion will be very useful for the large-scale production of biologically active recombinant proteins.

• The Journal of Korean Medicine
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• v.23 no.1
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• pp.133-144
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• 2002

Objectives : Korean traditional medicinal herbs have been used to improve the function of the hematopoietic system. The purpose of this study is to examine the hematopoietic effects of Juakium-derivative on aplastic anemia. Methods : In vitro, after bone marrow cells of mice with aplastic anemia induced by benzene were cultured with Juakium-derivative, we measured the gene expressions of hematopoietic cytokines, the intracellular TPO and SCF expression and the colony number of CFU-GEMM and BFU-E. Results : The results are summarized as follows : 1. The gene expressions of hematopoietic cytokines (TPO, c-mpl, SCF, c-kit, IL-3, EPO, EpoR, GM-CSF) and the TPO and SCF expression of the group treated with Juakium-derivative increased significantly more than those of the control group. 2. The colony number of CFU-GEMM and BFU-E in the rEPO plus rIL-3 plus Juakium-derivative group increased significantly compared with the only rEPO plus rIL-3 group. Conclusion : It was acknowledged that Juakium-derivative has hemato-potentiating effects on aplastic anemia induced by benzene and it is expected that Juakium-derivative can be used clinically for the patient with hematopoietic system disorder. This study could also be used further as important research data for Korean oriental medicine about hemato-potentiating. The exact mechanism explaining our study would need to be studied further.

• Steel and Composite Structures
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• v.49 no.2
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• pp.181-196
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• 2023

Marine structures including offshore wind turbines (OWTs) always work under cyclic loads, which arouses much attention on the fatigue design. The tripod substructure is one of the typical foundation forms for fixed OWTs. The three-planar tubular Y-joint (3Y joint) is one of the important components in fatigue design as it is most likely to have cracks. With the existence of the multiplanar interaction effect, calculating the hot spot stress (HSS) of 3Y joints is complicated. To assist with fatigue design, the distributions of stress concentration factor (SCF) and multiplanar interaction factor (MIF) along weld toe curves induced by the out-of-plane bending moment are explored in this study. An FE analysis method was first developed and verified against experimental results. This method was applied to build a numerical database including 1920 FE models covering common ranges of geometric parameters. A parametric study has been carried out to reveal the distribution patterns of SCF and MIF. After multidimensional nonlinear fittings, SCF and MIF distribution formulas have been proposed. Accuracy and reliability checking prove that the proposed formulas are suitable for calculating the HSS of 3Y joints.

• Clinical and Experimental Reproductive Medicine
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• v.39 no.3
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• pp.107-113
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• 2012

Objective: To determine whether animal age impacts in vitro preantral follicle growth. Effects of hCG, stem cell factor (SCF), and/or insulin-like growth factor (IGF) supplementation in growth medium were also investigated. Methods: Intact preantral follicles were mechanically isolated from fresh ovaries of BDF1 mice and cultured in growth medium for 9 to 11 days. Surviving follicles with antrum formation were transferred to maturation medium for 14 to 18 hours. Follicle survival, antrum formation, and retrieval of metaphase II (MII) oocytes were compared among three age categories (4-5, 7-8, and 10-11 week-old). By using 7- to 8-week-old mice, preantral follicles were cultured in growth medium supplemented with hCG (0, 5, or 10 mIU/mL), SCF (50 ng/mL), IGF-1 (50 ng/mL), and SCF+IGF-1. Results: Seven- to eight-week-old mice showed a higher follicle survival and antrum formation and produced more MII oocytes compared to other groups. In the 7- to 8-week-old mice, supplementation of 5 mIU/mL hCG significantly enhanced the antrum formation but the percentage of MII oocytes was similar to that of the control. Supplementation of SCF+IGF-1 did not enhance follicle survival or antrum formation but the percentage of MII oocytes increased modestly (39.1%) than in the control (28.6%, p>0.05, statistically not significant). Conclusion: Seven- to eight-week-old mice showed better outcomes in growth of preantral follicles in vitro than 4- to 5- or 10- to 11-week-old mice. Supplementation of hCG enhanced antrum formation and supplementation of SCF+IGF-1 yielded more mature oocytes; hence, these should be considered in the growth of preantral follicles in vitro.

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 1996.10a
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• pp.201-204
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• 1996

• Bulletin of the Korean Chemical Society
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• v.8 no.3
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• pp.221-223
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• 1987