• Title/Summary/Keyword: SC1

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A Dynamic Prefetch Filtering Schemes to Enhance Usefulness Of Cache Memory (캐시 메모리의 유용성을 높이는 동적 선인출 필터링 기법)

  • Chon Young-Suk;Lee Byung-Kwon;Lee Chun-Hee;Kim Suk-Il;Jeon Joong-Nam
    • The KIPS Transactions:PartA
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    • v.13A no.2 s.99
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    • pp.123-136
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    • 2006
  • The prefetching technique is an effective way to reduce the latency caused memory access. However, excessively aggressive prefetch not only leads to cache pollution so as to cancel out the benefits of prefetch but also increase bus traffic leading to overall performance degradation. In this thesis, a prefetch filtering scheme is proposed which dynamically decides whether to commence prefetching by referring a filtering table to reduce the cache pollution due to unnecessary prefetches In this thesis, First, prefetch hashing table 1bitSC filtering scheme(PHT1bSC) has been shown to analyze the lock problem of the conventional scheme, this scheme such as conventional scheme used to be N:1 mapping, but it has the two state to 1bit value of each entries. A complete block address table filtering scheme(CBAT) has been introduced to be used as a reference for the comparative study. A prefetch block address lookup table scheme(PBALT) has been proposed as the main idea of this paper which exhibits the most exact filtering performance. This scheme has a length of the table the same as the PHT1bSC scheme, the contents of each entry have the fields the same as CBAT scheme recently, never referenced data block address has been 1:1 mapping a entry of the filter table. On commonly used prefetch schemes and general benchmarks and multimedia programs simulates change cache parameters. The PBALT scheme compared with no filtering has shown enhanced the greatest 22%, the cache miss ratio has been decreased by 7.9% by virtue of enhanced filtering accuracy compared with conventional PHT2bSC. The MADT of the proposed PBALT scheme has been decreased by 6.1% compared with conventional schemes to reduce the total execution time.

Anti Inflammatory Activity of Viburnum dilatatum Thunb. Extract as Cosmetic Ingredient (화장품 소재로서 가막살나무 추출물의 항염증 효능)

  • Kwon, Yoo-Bin;Yoo, Byoung-Sam;Kim, Dae-Shin;Moon, Seong-Joon;Yoon, Moung-Seok;Park, Soo-Nam
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.36 no.3
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    • pp.183-191
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    • 2010
  • The crude ethanol extracts and their solvent-partitioned fractions derived from the leaf and twig of Viburnum dilatatum Thunb. were investigated for their 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging efficacy. The results showed that the butanol-soluble fraction ($SC_{50}\;=\;110.30\;{\mu}g/mL$) exhibited higher anti-oxidant activity than the crude ethanol extract ($SC_{50}\;=\;117.03\;{\mu}g/mL$) in the DPPH assay model. Then, the effects of the same extract samples on the production of nitric oxide were examined in LPS-stimulated RAW264.7 cells. Although the hexane and methylene chloride-soluble fraction showed a weak anti-oxidant activity, they exhibited potent inhibitory activity of NO production above 50 % at a concentration of $10\;{\mu}g/mL$. The hexane-soluble fraction also showed the inhibitory effect on mRNA expression of pro-inflammatory mediators such an TNF-$\alpha$, IL-$1{\beta}$, IL-6, iNOS and COX-2 in LPS-stimulated RAW264.7. These results suggest that the solvent extracts of Viburnum dilatatum Thunb. could be used as an anti-irritation ingredient.

Global Temperature Trends of Lower Stratosphere Derived from the Microwave Satellite Observations and GCM Reanalyses (마이크로파 위성관측과 모델 재분석에서 조사된 전지구에 대한 하부 성층권 온도의 추세)

  • Yoo, Jung-Moon;Yoon, Sun-Kyung;Kim, Kyu-Myong
    • Journal of the Korean earth science society
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    • v.22 no.5
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    • pp.388-404
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    • 2001
  • In order to examine the relative accuracy of satellite observations and model reanalyses about lower stratospheric temperature trends, two satellite-observed Microwave Sounding Unit (MSU) channel 4 (Ch 4) brightness temperature data and two GCM (ECMWF and GEOS) reanalyses during 1981${\sim}$1993 have been intercompared with the regression analysis of time series. The satellite data for the period of 1980${\sim}$1999 are MSU4 at nadir direction and SC4 at multiple scans, respectively, derived in this study and Spencer and Christy (1993). The MSU4 temperature over the globe during the above period shows the cooling trend of -0.35 K/decade, and the cooling over the global ocean is 1.2 times as much as that over the land. Lower stratospheric temperatures during the common period (1981${\sim}$1993) globally show the cooling in MSU4 (-0.14 K/decade), SC4 (-0.42 K/decade) and GEOS (-0.15 K/decade) which have strong annual cycles. However, ECMWF shows a little warming and weak annual cycle. The 95% confidence intervals of the lower stratospheric temperature trends are greater than those of midtropospheric (channel 2) trends, indicating less confidence in Ch 4. The lapse rate in the trend between the above two atmospheric layers is largest over the northern hemispheric land. MSU4 has low correlation with ECMWF over the globe, and high value with GEOS near the Korean peninsula. Lower correlations (r < 0.6) between MSU4 and SC4 (or ECMWF) occur over $30^{\circ}$N latitude belt, where subtropical jet stream passes. Temporal correlation among them over the globe is generally high (r > 0.6). Four kinds of lower stratospheric temperature data near the Korean peninsula commonly show cooling trends, of which the SC4 values (-0.82 K/decade) is the largest.

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The Evaluation of Image Correction Methods for SPECT/CT in Various Radioisotopes with Different Energy Levels (SPECT/CT에서 서로 다른 에너지의 방사성동위원소 사용시 영상보정기법의 유용성 평가)

  • Shin, Byung Ho;Kim, Seung Jeong;Yun, Seok Hwan;Kim, Tae Yeop;Lim, Jung Jin;Woo, Jae Ryong;Oh, So Won;Kim, Yu Kyeong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.2
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    • pp.53-58
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    • 2013
  • Purpose: To optimize correction method for SPECT/CT, image quality consisting of resolution and contrast was evaluated using three radioisotopes ($^{99m}Tc$, $^{201}Tl$ and $^{131}I$) and three different correction methods; attenuation correction (AC), scatter correction (SC) and both attenuation and scatter correction (ACSC). Materials and Methods: Images were acquired with a SPECT/CT scanner and a conventional CT protocol with an OESM reconstruction algorithm (2 iterations and 10 subsets). For resolution measurement, fixed radioactivity (2.22 kBq) was infused into a spatial resolution phantom and full width at half maximum (FWHM) was measured using a vendor-provided software. For contrast evaluation, radioactive source with a ratio of 1:8 to background was filled in a Flanged Jaszczak phantom and percent contrast (%) were calculated. All the parameters for image quality were compared with non-correction (NC) method. Results: As compared with NC, image resolution of all three isotopes were significantly improved by AC and ACSC, not by SC. In particular, ACSC showed better resolution than AC alone for $^{99m}Tc$ and $^{201}Tl$. Image contrast of all three radioisotopes in a sphere with the largest diameter were enhanced by all correction methods. ACSC showed the highest contrast in all three radioisotopes, which was the most accurate in $^{99m}Tc$ (85.9%). Conclusion: Image quality of SPECT/CT was improved in all the radioisotopes by CT-based attenuation correction methods, except SC alone. SC failed to improve resolution in any radioisotopes, but it was effective in contrast enhancement. ACSC would be the best correction method as it improved resolution in radioisotopes with low energy levels and contrast in radioisotope with low energy levels. However, in radioisotope with high energy level, AC would be better than ACSC for resolution improvement.

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Changes in Fatty Acid Composition and Phytosterol Content in Double Cropping Maize (이기작에 따른 옥수수의 지방산 조성 및 Phytosterol 함량 변화)

  • Kim, Sun-Lim;Jung, Gun-Ho;Kim, Mi-Jung;Son, Beom-Young;Kim, Jung-Tae;Bae, Hwan-Hee;Go, Young-Sam;Yi, Gibum;Lee, Jin-Seok;Baek, Seong-Bum
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.65 no.2
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    • pp.93-103
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    • 2020
  • The average growth day of 11 maize varieties from planting to silking in the first cropping (FC) was 89.5 days and in the second cropping (SC) was 46.7 days, which was 43 days faster than in the FC. The average 100-kernel weight (100 KW) in the FC was 28.4 g and 18.3 g in the SC, which was approximately 36.4% lower than that in the FC. The average crude oil content of FC was 3.97% and SC was 3.08%, which was about 0.89% lower than that of FC. The composition of stearic and oleic acid was significantly higher in FC, whereas palmitic and linoleic acid were higher in SC; however, linolenic acid was not statistically different between the two crops. The crude oil content was negatively correlated with linoleic acid (FC -0.264ns, SC -0.504**) and positively correlated with linolenic acid (0.526**). Unsaturated fatty acid (USFA) composition showed a significant difference between FC (83.48%) and SC (82.96%). Total phytosterol content was 598.3 mg/100 g and 701.9 mg/100 g in FC and SC, respectively, and showed significant difference by planting dates. The β-sitosterol content showed no statistical difference between the planting dates, but campesterol and stigmasterol were significantly higher in SC than in FC. Therefore, it was considered that the temperature condition during the ripening period affects the 100 KW of maize, and this leads to the variation in phytosterol content. However, among phytosterols, β-sitosterol was relatively little affected by the planting dates. USFA composition showed a significantly negative correlation with phytosterol content. Considering the results, the relatively high phytosterol content in SC was mainly because of the delay in progress of starch accumulation as daily air temperature decreased from the middle of the ripening period, whereas progress of phytosterol accumulation in the maize kernel was considered relatively faster than that of starch accumulation.

Anti-fatigue effect of a cucumber vinegar beverage on rats after high-intensity exercise (고강도 운동을 실시한 흰쥐에 대한 오이식초음료의 항피로 효과)

  • Cho, Hyun Dong;Kim, Jeong Ho;Lee, Ju Hye;Hong, Seong Min;Yee, Sung Tae;Seo, Kwon Il
    • Korean Journal of Food Science and Technology
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    • v.49 no.2
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    • pp.209-214
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    • 2017
  • We evaluated the effect of cucumber vinegar (CV) on fatigue accumulation in rats that performed high-intensity exercise. The rats were randomly assigned to 3 groups: sedentary control (SC), exercise control (EC), and CV. Body weights were higher in groups EC and CV than in group SC. Organ weights in group CV did not differ from those in group SC. Running time was significantly longer in group CV than in the other groups. Compared to group EC, cucumber vinegar administration markedly decreased serum concentrations of ammonia, inorganic phosphate, and ${{\small}L}$-lactate. The activities of serum creatine kinase and lactate dehydrogenase were significantly lower in group CV than in groups SC and EC. Glycogen contents in the muscle and liver were higher in group CV than in groups SC and EC. These results suggest that cucumber vinegar can serve as a functional ingredient in the development of a beverage to attenuate fatigue.

Energy metabolism and whole-exome sequencing-based analysis of Sasang constitution: a pilot study

  • Kim, Hyoung Kyu;Lee, Heetak;So, Ji Ho;Jeong, Seung Hun;Seo, Dae Yun;Kim, Jong-Yeol;Kim, Sanguk;Han, Jin
    • Integrative Medicine Research
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    • v.6 no.2
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    • pp.165-178
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    • 2017
  • Background: Traditional Korean Sasang constitutional (SC) medicine categorizes individuals into four constitutional types [Tae-eum (TE), So-eum (SE), Tae-yang (TY), or So-yang (SY)] based on biological and physiological characteristics. As these characteristics are closely related to the bioenergetics of the human body, we assessed the correlation between SC type and energy metabolism features. Methods: Forty healthy, young ($22.3{\pm}1.4$ years) males volunteered to participate in this study. Participants answered an SC questionnaire, and their face shape, voice tone, and body shape were assessed using an SC analysis tool. Thirty-one participants (10 TE, 10 SE, 3 TY, and 8 SY) were selected for further analysis. Collected blood samples were subjected to blood composition analysis, mitochondrial function analysis, and whole-exome sequencing. Results: The SY type showed significantly lower total cholesterol and high-density lipoprotein cholesterol levels than the SE type. Cellular and mitochondrial Adenosine triphosphate (ATP) levels were similar across types. All types showed similar basal mitochondrial oxygen consumption rates, whereas the TE type showed a significantly lower ATP-linked oxygen consumption rate than the other types. Whole-exome sequencing identified several genes variants that were exclusively detected in particular SC types, including 19 for SE, seven for SY, 11 for TE, and six for TY. Conclusion: SC type-specific differences in mitochondrial function and gene mutations were detected in a small group of healthy, young Korean males. These results are expected to greatly improve the accurate screening and utilization of SC medicine.

Production of a transgenic pig expressing 3D8 single chain variable fragment (scFv) and its evaluation of PRRS resistant (3D8 scFv 형질전환 돼지 개발 및 PRRS 저항성 평가)

  • Lee, Hwi-Cheul;Lee, Gunsup;Kim, Ji-Yoon;Yang, Hyeon;Lee, Bo Ram;Park, Mi-Ryung;Hwang, In-Sul;Lee, Poongyeon;Byun, Sung-June;Kim, Won-Il;Oh, Keon Bong
    • Korean Journal of Veterinary Service
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    • v.43 no.4
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    • pp.227-236
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    • 2020
  • In this study, we have developed 3D8 scFv transgenic pig (TG) by microinjection of fertilized one-cell pig zygotes (2.17%). The effect of 3D8 scFv TG on porcine reproductive and respiratory syndrome virus (PRRSV) resistance were evaluated through PRRSV VR2332 (1×103 TCID50/mL) challenge and transmission experiments. As a result, the average daily weight gain (ADWG) of TG increased compared to the wild type pigs (WT) in PRRSV challenge groups and the serum viremia levels of the TG was significantly lower than of WT on the 7 day and 21 day after infection, meaning that the viral shedding was suppressed by 3D8 scFv expression. These results suggest that the expression of 3D8 scFv in pig could suppress spreading of infected virus to pigs sharing a room.