• Asian Pacific Journal of Cancer Prevention
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• 제16권13호
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• pp.5415-5420
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• 2015

Background: The present study was designed to ascertain knowledge about HPV, cervical cancer (CC) and the Pap test among female dental students of Panineeya Institute of Dental Sciences and Hospital, Hyderabad, India. Materials and Methods: A self-administered questionnaire covering demographic details, knowledge relating to human papilloma virus (HPV) (8 items), cervical cancer (4 items) and the Pap smear (6 items) was employed. Responses were coded as "True, False and Don't Know". Mean and standard deviation (SD) for correct answers and levels of knowledge were determined. Results: Based on the year of study, significant differences in knowledge of HPV werenoted for questions on symptoms (p=0.01); transmission from asymptomatic partners (p=0.002); treatment with antibiotics (p=0.002); start of sexual activity (p=0.004); and recommended age for HPV vaccination (p=0.01). For knowledge regarding CC, significance was observed for the age group being affected (p=0.008) and symptoms of the disease in early stages (p=0.001). Indications for Pap smear tests like symptoms' of vaginal discharge (p=0.002), marital status (p=0.01) and women with children (p=0.02) had significant difference based on the year of study. Based on religion, transmission of HPV via pregnancy, HPV related diseases except CC and preventive measures except condom use and oral contraceptives showed significant differences. However, significant variation with religion was observed only for two preventive measures of CC (Pap test; p=0.004) and HPV vaccination (p=0.003). Likewise, only the frequency of Pap test showed a significant difference for religion (p=0.001). Conclusions: This study emphasizes the lack of awareness with regard to HPV, CC and screening with pap smear even among health professionals. Hence, regular health campaigns are essential to reduce the disease burden.

• Asian Pacific Journal of Cancer Prevention
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• 제15권20호
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• pp.8679-8684
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• 2014

CD133 was recently reported to be a cancer stem cell and prognostic marker. Quercetin is considered as a potential chemopreventive agent due to its involvement in suppression of oxidative stress, proliferation and metastasis. In this study, the expression of CD133/CD44 in esophageal carcinomas and Eca109/9706 cells was explored. In immunoflurorescence the locations of $CD133^+$ and multidrug resistance 1 $(MDR1)^+$ in the same E-cancer cells were coincident, mainly in cytomembranes. In esophageal squamous cell carcinomas detected by double/single immunocytochemistry, small $CD133^+$ cells were located in the basal layer of stratified squamous epithelium, determined as CSLC (cancer stem like cells); $CD44^+$ surrounding the cells appeared in diffuse pattern, and the larger $CD44^+$ (hi) cells were mainly located in the prickle cell layer of the epithelium, as progenitor cells. In E-cancer cells exposed to nanoliposomal quercetin (nLQ with cytomembrane permeability), down-regulation of NF-${\kappa}Bp65$, histone deacetylase 1 (HDAC1) and cyclin D1 and up-regulation of caspase-3 were shown by immunoblotting, and attenuated HDAC1 with nuclear translocation and promoted E-cadherin expression were demonstrated by immunocytochemistry. In particular, enhanced E-cadherin expression reflected the reversed epithelial mesenchymal transition (EMT) capacity of nLQ, acting as cancer attenuator/preventive agent. nLQ acting as an HDAC inhibitor induced apoptotic cells detected by TUNEL assay mediated via HDAC-NF-${\kappa}B$ signaling. Apoptotic effects of liposomal quercetin (LQ, with cytomembrane-philia) combined with CD133 antiserum were also detected by CD133 immunocytochemistry combined with TUNEL assay. The combination could induce greater apoptotic effects than nLQ induced alone, suggesting a novel anti-CSC treatment strategy.

• 대한기계학회논문집B
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• 제27권3호
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• pp.275-285
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• 2003

A visualization study on the effect of forcing amplitude in tone-excited jet diffusion flames has been conducted. Visualization techniques are employed using optical schemes. which are a light scattering photography. Flame stability curve is attained according to Reynolds number and forcing amplitude at a fuel tube resonant frequency. Flame behavior is globally grouped into two from attached flame to blown-out flame according to forcing amplitude: one sticks the tradition flame behavior which has been observed in general jet diffusion flames and the other shows a variety of flame modes such as the flame of a feeble forcing amplitude where traditionally well-organized vortex motion evolves, a fat flame. an elongated flame. and an in-burning flame. Particular attention is focused on an elongation flame. which is associated with a turnabout phenomenon of vortex motion and on a reversal of the direction of vortex roll-up. It is found that the flame length with forcing amplitude is the direct outcome of the evolution process of the formed inner flow structure. Especially the negative part of the acoustic cycle under the influence of a strong negative pressure gradient causes the shapes of the fuel stem and fuel branch part and even the direction of vortex roll-up to dramatically change.

• 대한관절경학회지
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• 제16권2호
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• pp.175-179
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• 2012

활막 연골종증(synovial chondromatosis)은 관절 활막에 존재하는 활액막 세포가 연골모세포로의 화생에 의해 발생하는 것으로 슬관절, 고관절 등의 큰 관절에 주로 발생하며 견관절에 발생하는 경우는 드물다. 술전에 진단하기는 어려운 경우가 많으며, 수술적 활액막 절제술이 치료에 효과적이다. 저자들은 어깨 관절의 불편감과 통증을 호소하는 44세 여자환자에서 초자연골로 구성된 유리체를 동반한 견봉하 공간의 연골종증을 경험하여 이를 문헌 고찰과 함께 보고하고자 한다.

• 한국재료학회지
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• 제30권10호
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• pp.495-501
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• 2020

The various sintered samples comprising of 72 wt% (Al₂O₃) : 28 wt% (SiO₂) based ceramics were fabricated using a colloidal processing route. The phase analysis of the ceramics was performed using an X-ray diffractometer (XRD) at room temperature confirming the presence of Al₂O₅Si and Al_5.33Si_0.67O_9.33. The surface morphology of the fracture surface of the different sintered samples having different sizes of grain distribution. The resistive and capacitive properties of the three different sintered samples at frequency sweep (1 kHz to 1 MHz). The contribution of grain and the non-Debye relaxation process is seen for various sintered samples in the Nyquist plot. The ferroelectric loop of the various sintered sample shows a slim shape giving rise to low remnant polarization. The excitation performance of the sample at a constant electric signal has been examined utilizing a designed electrical circuit. The above result suggests that the prepared lead-free ceramic can act as a base for designing of dielectric capacitors or resonators.

• 한국압력기기공학회 논문집
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• 제11권1호
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• pp.20-24
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• 2015

Steam generator(S/G) tubes in pressurized water reactor (PWR's) are subject to several types of degradation. This degradation includes denting, pitting, intergranular attack(IGA), intergranular stress corrosion cracking(IGSCC), fatigue, fretting and wear. Degradation can be derived from either the primary side(inside) or the secondary side(outside) of the tube. Recent issue for tube degradation in domestic steam generator is the tube end cracking on seal weld region. The seal weld region at the tube end and tube itself is regarded as a pressure boundary between the primary side and the secondary side. One of the Westinghouse Model-F S/G has experienced tube end cracking and its number of plugging approximately becomes to the operating limit up to 5% due to tube end cracking which was reported as SAI/MAI(single/multiple axial indication) or SCI/MCI(Single/multiple circumferential indication) from the results of eddy current testing. Eddy current mock-up test was carried out to determine the origin of cracking whether it is from weld zone area or parent tube. This result was helpful to analyze crack location on ECT data. Correct action on this problem was the installation of tube-end sleeve. Last year, after removing 340 installed plugs from tubes, selected 269 tubes took tube-end sleeve installation. Tube-end sleeve brought pressure boundary from parent tube to installed sleeve tube. Tube-end sleeve has the benefit of reducing outage period and increasing more revenue than replacing S/G. This paper is provided to assist interest parties in effectively understanding this issue.

• 대한정형외과스포츠의학회지
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• 제6권2호
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• pp.115-118
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• 2007

대흉근 파열은 주로 활동적인 젊은 성인이나 격렬한 경기와 관련된 운동선수에게서 발생하고, 특히 웨이트 트레이닝 도중에 발생하는 경우가 많다고 알려져 있다. 흔치 않은 손상이 나 최근 스포츠 활동 인구의 증가로 대흉근 파열의 발생은 증가 추세에 있으며 이에 따라 기능적 및 미용적 회복을 위한 다양한 수술적 치료 방법이 소개되고 있다. 저자들은 벤치프레스 도중 발생하였으나 진단이 불명확하여 적절한 치료를 시행하지 못하고 수상 후 5개월 만에 진단된 대흉근 파열에 대하여 골경유 봉합 및 봉합나사를 이용한 봉합술을 시행한 1례를 경험하였기에 문헌고찰과 함께 보고하고자 한다.

• 한국농공학회지
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• 제34권2호
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• pp.49-59
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• 1992

In our researches we made mix-design, with the mixing ratio and pre-cracked ratio of steel fibrous different from each other, building the steel fibrous concrete beam which had pre-cracks. To obtain the fracture characteristics of steel fibrous reinforced concrete, series of experiment were conducted on pre-cracked beam subjected to 3-point bending. Thus, we carried out experiments on the destructive characteristics of its pre-crack and post-crack and the result is as follows. 1. The compressive strength of steel fibrous concrete beam increased more slightly than plane beam, and the tensile strength increased 37%, 59%, 94% and 121% respectively when the amount of fibrous was 0.5%, 0.1% 1.5%, and 1.75% respectively. 2. As the amount of steel fibrous mixing increased ant the steel fibrous inhibited the crack growth, the crack condition of steel fibrous concrete beam was retarded irregularly, and this increased fracture load. 3. The defiance of destruction was reduced in the ratio of 1.35 times and 1.22 times respectively when the length of pre-crack was each 2cm and 4cm in comparison with the case of being without the length, and was similar to that of plane beam when the amount of steel fibrous mixing was below 1.0%, and increased linearly when it as above 1.0%. 4. The experimental formula seeking fracture energy was follows and thus we found that the value of fracture energy depended upon tensile strength and the size of speciment. $G_f=K\;{\cdot}\;f_f^'{\cdot}$da/Ec 5. We observed that in the load-strain curve of steel fibrous concrete beam the progress of the crack became slow, compared with plane beam because the crack condition became long to the extent of about 10 times. Concrete was faultiest brittleness fracture through the study, it was known ductile.

• 미생물학회지
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• 제25권4호
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• pp.282-289
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• 1987

Pseudomonas putida KU816에서 분리한 플라스미드 pKU10의 여러가지 특성을 조사하고 그 제한 효소 지도를 작성하였다. pKU 10은 암펴설런, 테트라사이클린, 클로람페니콜에 대한 내성 유전자를 갖는 작은 R factor로서 마이토마이신 C에 의하여 큐어링 된다. 플라스미드의 크기는 9.4Kb로 측정되었다. pKU 10은 Pseudomonas와 E.coli블 숙주로 하였을 때 안정하게 형질 발현이 되다. 또한 pKU 10의 불화합성균은 IncP-I으로 조사되었다. Eco RI, Xho I. SaiI, BglII, SmaI은 pKU 10 DNA를 한 부위에서 자르고, Pst I은 두 부위, Hind Ill는 여섯 부위에서 자른다. 제한 효소 지도는 제한 효소를 이중, 삼중으로 완전 소화시키거나, 부분 소화시켜서 얻었다. pKU 10은 Pseudomonas속에서 유용한 클로닝 벡터호 이용된 것으로 기대된다.

• 비파괴검사학회지
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• 제32권5호
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• pp.551-563
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• 2012

초음파진단기는 1950년대부터 사용되기 시작했고 그 동안 꾸준한 기술 발전을 통해 현재 대부분의 병원에서 필수불가결한 영상진단장비로 널리 활용되고 있다. 1970년대 초음파진단기에 어레이 프로브가 사용되기 시작한 이래로 전자적 신호처리를 통한 빔포밍 기술이 초음파진단기에 적용되었고, 꾸준히 개선되어 왔다. 빔포밍 기술은 초음파진단기의 해상도를 결정짓는 중요한 신호처리 기술이다. 이 논문에서는 이 빔포밍 기술의 원리부터 최근 동향까지 간략히 소개하고자 한다. 여기에는 어레이 프로브(array probe)를 사용하는 빔포밍의 원리, 기본적 이론, 실제 구현 등이 포함되고, 또 최근 기술 중 합성구경영상(synthetic aperture imaging: SAI), 적응형 빔포밍(adaptive beamforming), 2차원 어레이 프로브를 사용하는 2차원 빔포밍 기술 등의 주제도 소개한다. 이런 다양한 빔포밍 기술들은 다양한 다른 분야의 기술들과 여러 가지 형태로 발전적으로 융합하면서 시스템의 성능을 지속적으로 향상시켜 갈 것이다.