• 한국임상수의학회지
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• 제38권2호
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• pp.89-93
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• 2021

2-Month-old, three related Perro de Presa Canario dogs were evaluated for similar neurological symptoms like circling, head pressing, depressed mental status, hypermetria, and vocalization. On magnetic resonance imaging (MRI) of the brain, there were large, bilaterally symmetrical lesions with involvement of thalamus, and brainstem that were T2- and FLAIR-hyperintense and T1-iso/hypointense. There was no inclusion of cerebellum. Single-voxel spectroscopy acquisition was located in the thalamus where abnormalities were found in MR images. The results of magnetic resonance spectroscopy (MRS) showed markedly decreased N-acetylaspartic acid value. Euthanasia was performed and lesions consistent with the canine spongy degeneration. Alteration in metabolites in the brain can be determined by MRS, which helps in diagnosing degeneration/leukodystrophy of the central nervous system in dogs.

• 한국대기환경학회지
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• 제27권4호
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• pp.395-404
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• 2011

Asian dust evens took place in Seoul on 27~28 March and 31 March~1 April 2007, during which the mass and chemical compositions of $PM_{10}$ were measured at urban area in Seoul, Korea. In conjunction with $PM_{10}$ compositions, the behaviors of gas precursors such as CO, $O_3$, $SO_2$, and $NO_2$ and meteorological parameters and air mass trajectories were thoroughly examined. The earlier case was a weak dust incidence which was characterized by elevated concentrations of CO, $SO_2$ and $NO_2$ as well as secondary aerosols. In contrast, the later showed the trait of the dust aerosols associated with high $PM_{10}$ mass and $Ca^{2+}$ concentrations. In general, the fractions of ionic species against mass decreased with increase in dust loading. The ratios of ${SO_4}^{2-}$ to ${NO_3}^-$ and $SO_2$ to $NO_2$ were similar in temporal variations, suggesting the concentrations of secondary aerosols were sensitive to the level of precursor gases. In this study, $Na^+$ and $Cl^-$ were also highly elevated during the heavy dust episode, which is thought to have originated from alkaline soils spreading through the northeast regions of China.

• Journal of Korean Neurosurgical Society
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• 제38권3호
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• pp.221-226
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• 2005

Objective : Reactive oxygen metabolites and polymorphonuclear leukocytes have been implicated in the pathophysiology of reperfusion injury. The mechanisms involved in superoxide-mediated leukocyte adherence remain unclear, however, nitric oxide[NO] may contribute to this response. The present study is undertaken to elucidate mechamisms controlling NO based mechanisms that regulated leukocyte-endothelial interactions in the cerebral vasculature after global cerebral ischemia and reperfusion. Methods : Pial venular leukocyte adherence of anesthetized newborn piglets was quantified by in situ fluorescence videomicroscopy through closed cranial windows during basal conditions and during 2hours of reperfusion after global ischemia induced by 9minutes of asphyxia. Nitric oxide synthase[NOS] was inhibited by local window superfusion of L-nitroarginine[NA]; superfusion of sodium nitroprusside[SNP] was used to donate NO. Results : The mean number of adherent leukocytes to cerebral venules in the 9minutes asphyxia and 2hours reperfusion group were $161{\pm}19$ compared with $13{\pm}4$ in the nonasphyxial group. Superfusion of L-NA through the cranial window for 2hours resulted in leukocyte adherence similar to that observed during the initial 2hours of reperfusion after asphyxia. Leukocyte adherence was not additionally increased in asphyxic animal treated with L-NA. SNP inhibited asphyxia induced leukocyte adherence back to control levels. Conclusions : Nitric oxide inhibits leukocyte adherence to cerebral venules during the initial hours of reperfusion after asphyxia, and that NO supplementation inhibit asphyxia induced leukocyte adherence back to control levels. These results indicate that NO is an important factor in ischemia-reperfusion induced leukocyte adherence.

• Clinical and Experimental Reproductive Medicine
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• 제17권1호
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• pp.65-70
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• 1990

Clinical effects of intramuscular injection of 250mg testosterone cypionate every 2-3 weeks were investigated in 15 impotent patients with low or low normal serum testosterone level (Hypo-gonadotrophic hypogonadism was excluded). The results were obtained as follows. 1. Among 15 patients, 7(46.7%) showed markedly improved potency, 6(40%) partially improved potency and 2(13.7%) no improvement of potency. There was no correlation between effec-tiveness of testosterone replacement and age, testicular size, serum testosterone level or LH, FSH level. 2. Among 12 patients who had showed improved potency, 8(66.7%) complained of redeveloped decrease in potency during testosterone replacement. In conclusion, testosterone cypionate for treatment of the impotent patients with low or low normal serum testosterone level was effective, but further studies are necessary to investigate cause of redeveloped decrease in potency during testosterone replacement.

• Tribology and Lubricants
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• 제28권3호
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• pp.112-116
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• 2012

wet-type multiple disk brakes are very important parts of turning decelerator for deck crane, because they are advanced in durability and braking power, and can be designed compactly. Thus, we designed and made wet-type multiple disk brakes of turning decelerator for deck crane to be localization of these imported all. In this study, wet multiple disk brakes were made a comparative test with the 2 types materials of friction disk by the SAE No.2 dynamometer. The friction characteristics were measured and analyzed to decide a suitable material as wear depth of friction disk and dynamic and static friction coefficient.

• 약학회지
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• 제52권1호
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• pp.43-47
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• 2008

To determine the regulatory roles of PDE4 inhibitor on LPS-induced osteoclastogenesis, we investigated the effect of a PDE4 inhibitor on osteoclast formation in the presence of LPS. A specific PDE4 inhibitor, rolipram, increased LPS-induced osteoclast formation in cocultures. To verify that whether rolipram acts indirectly on osteoblasts, we investigated the TRANCE and COX-2 mRNA expression levels in osteoblasts. Treatment of rolipram increased the expression of TRANCE and COX-2 mRNA in osteoblasts stimulated by LPS. On the contrary, rolipram did not augment the number of osteoclasts differentiated from bone marrow cells by LPS. In conclusion, the stimulation of LPS-induced osteoclast formation by the PDE4 inhibitor are attributable to its indirect effect on osteoblasts, not to their direct effect on bone marrow-derived osteoclast precursors.

• 대한치과교정학회지
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• 제12권2호
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• pp.155-164
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• 1982

The purpose of this study was to investigate the changes of bony and soft tissue by the growth Each 50 boys and girls was studied aged 7 through 9 years old. The results were as follows; 1. Thickness of soft tissue was increased by the growth and much more done in boys than in girls. 2. In the linear measurement of soft tissue change of A-A' was most remarkable. 3. Nose length was increased in both boys and girls. Remarkable change was observed in male aged 8 through 9 years old and in female aged 7 through 8 years old. 4. In the linear measurement of bony tissue change, S-Pg, Go-Me, S-A, and S-N were increased in sequence. 5. Point-A and Pg in bony tissue grow more downward direction than forward. 6. In the angular measurement, no significant change was observed.

• 한국축산시설환경학회지
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• 제19권2호
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• pp.191-196
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• 2013

In this study, the mixture ratio included 20% (GLY 20), 40% (GLY 40), and 60% (GLY 60) based on VS with the control group (GLY 0) with no crude glycerin added. Maintaining stable pH, GLY 20 and GLY 0 showed the highest total output of biogas (1.24 L/L/d) and methane(0.78 L/L/d) as its volatile solids reduction rate was 53.56%. In case of GLY 40 and GLY 60, their pH was rapidly reduced after seven days of the study, so that their anaerobic digestion was all stopped.In the results of the study, it is desirable to add crude glycerin less than 20%, and it would be necessary to have the future researches on more detailed organic loading rate of each ratio, and analysis on economic feasibility.

• 산업경영시스템학회지
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• 제24권68호
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• pp.37-50
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• 2001

Although the study of OCB has increased greatly in recent years, a little works have focused on the relationship between leadership and extrarole behavior, and the moderating effects of the situational factors on the relationship between two factors. For the analytical purpose of this article, Fisher＇s Z-transformation and SGC(split groups correlations) methods were introduced. Generally 2 leadership styles are found to have influenced on altruism and conscientiousness respectively. Out of 36 cases, only 2 cases were significant in moderating effects. Based on empirical results, there is no moderating effects in conscientiousness. But altruism is found to be more closely related with employee-centered leadership in low centralized group than in high centralized group, and more closely related with job-centered leadership in low growth-needs group than in high growth-needs group.

• 한국자동차공학회논문집
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• 제23권3호
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• pp.352-359
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• 2015

This study investigates the analysis result of structure and fatigue due to the models of the hub space with bolt joint at wheel and the existence or nonexistence of hub ring as the part of suspension system of vehicle. As the static analysis result, the structural vulnerability can be found at hub bolt and the center of wheel at three models. Model 2 and 3 have nearly same deformation and model 1 can be endured at the least load among three models. As the fatigue analysis result, fatigue lives of three models are same at the severest load of SAE bracket history. As many screw threads of weak bolts are jointed in case of model 1, model 1 is shown to be the weakest at fatigue damage among three models. By the result of this study, model 1 with bolt joint becomes most weakest among three models. As model 2 with no hub ring and model 3 with hub ring have the nearly same states of analysis results, hub ring is shown to have no influence on the safety of automotive driving.