• Tuberculosis and Respiratory Diseases
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• 제65권4호
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• pp.318-322
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• 2008

저자들은 가슴벽의 양측 갈비뼈사이 공간에 발생한 신경집종으로 한쪽의 갈비사이 공간에 발생한 덩어리는 일반적인 신경집종과 달리 피하 방향으로 진행하는 양상을 보였던 양측성 신경집종을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 한국식품저장유통학회지
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• 제22권3호
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• pp.322-327
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• 2015

죽순분말을 첨가한 전병을 제조하여 첨가 수준별 품질특성을 조사하였다. 죽순분말 첨가 전병의 일반성분 중 조단백질, 식이섬유와 회분의 경우 죽순 분말 첨가량이 증가할수록 높아지는 경향을 보였고 조지방은 감소하였다. 유리아미노산 함량의 경우 죽순분말을 첨가할수록 증가하는 결과를 보였다. 색도에서 명도를 나타내는 L값은 죽순 분말 첨가량이 높아지면서 증가하였고, 무첨가구 시료와 타 시료간의 색차값을 비교한 ${\Delta}E$ 값의 변화는 죽순 분말 100 g 첨가구가 4.58로 나타나 죽순 분말 첨가가 전병 고유의 색에 영향을 주는 것으로 나타났다. 유리당 함량은 죽순 분말을 첨가하면서 다소 감소하는 것으로 나타났다. 관능에 따른 시료별 선호도 결과 죽순 300 g 첨가 시료가 색(color), 향미(flavor), 맛(taste), 식감(chewiness) 모두 가장 높은 값을 나타냈다. 전반적 기호도와 다양한 관능검사 결과를 종합하여 볼 때 전병에 첨가하는 죽순분말의 적정비율은 300 g 수준이 가장 좋은 것으로 나타났다.

• 한국축산식품학회지
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• 제26권3호
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• pp.368-374
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• 2006

We have studied on characterization and cheese making like mineral contents, protein composition and coagulation pattern on equine milk. At first, for contents of mineral on equine milk, It was lower in equine than bovine milk Contents of Na, Mg, P, Ca and K the major minerals, were indicated as 18.3 mg, 0.4 mg, 33.3 mg, 80.9 mg and 134.9 mg respectively by 100 g. In the distribution of nitrogen, the ratio NPN to Nt was indicated as 9.8% while that of bovine milk was 7%. And In NCN, its percentage was indicated as 45.6% shelving that Equine casein was lower than bovine. From these results, equine milk could not be applicable to cheese production since there are no coagulable nitrogen fraction such as ${\kappa}$-casein, as there aye with bovine milk. Equine milk will be more acceptable if we accept that the phylogenic affinity is near to human. It is the same as equine from the view points that monogastric, which did not contain ruminant's casein. For the rennet coagulation, equine milk was different than bovine milk. Equine milk did not coagulated by rennet after the addition of $Ca^{2+}$. But when bovine ${\kappa}$-casein was added in the presece of rennet, and $Ca^{2+}$ to equine milk, coagulation occurred. Such phenomenon was also observed by the use SEM. Verification of ${\kappa}$-casein by SDS-PACE did not existed in equine milk. The Casein of equine milk(54.4%) is similar to human milk in that casein/whey is about 1. For equine milt this can be explained because distance between casein and Ca is great, casein being lower, which result in reaction of casein with $Ca^{2+}$ because it could not activated which lasting time of coagulation is too long.

• 생태와환경
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• 제47권spc호
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• pp.19-30
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• 2014

Microcystins (MCs) produced by cyanobacteria are severe hepatotoxins for mammalian and protein phosphatase inhibitors. Irrigation water for grain and vegetables is often contaminated with cyanobacteria and microcystin during warm seasons. We assessed the effects of various concentrations (0, 0.01 to $10{\mu}gmL^{-1}$) of microcystin-LR (MC-LR) and microcystin-RR (MC-RR) exposure on Oryza sativa (rice) and Brassica oleraces var. italica (broccoli). The $EC_{50}$ of leaves and roots of rice was 0.9 and $1.1{\mu}gMC-LRmL^{-1}$, respectively. The no observed effect level (NOEL) of rice was less than $0.1{\mu}gmL^{-1}$ ($100{\mu}gL^{-1}$). The $EC_{50}$ of the stems and roots of broccoli was 8.7 and $7.2{\mu}gMC-RRmL^{-1}$, respectively. There was no difference in the germination rate of broccoli among microcystin-RR concentrations. After exposure to 0, 0.01 to $10{\mu}gmL^{-1}$ MC-RR for seven days, 14, 89 and 154 ng mg-1 (dry weight) MC-RR accumulated in B. oleracea. These $EC_{50}$ values showed that microcystin-LR and -RR affected the growth of rice and broccoli. These findings suggest that MC is carried into terrestrial ecosystems via irrigation, and that the biota of higher ecological niches can be influenced by MC through bioaccumulation. Therefore, a guideline for MC concentrations in irrigation water should be set using the NOEL.

• 대한두개안면성형외과학회지
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• 제14권1호
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• pp.61-64
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• 2013

Schwannomas are well-differentiated solitary benign tumors that originate from the schwann cells of the nerve sheath. They can readily occur in the head and neck regions, but the schwannoma originating from the infraorbital nerve is extremely rare and usually painless, slow-growing, and without specific symptoms. The author experienced a rare case of infraorbital schwannoma, which was completely removed through the intraoral approach. A 20-year-old woman was admitted to our hospital for a painless, solid and circular mass located on the right infraorbital region. The eyeball movement and visual field were normal. There was no globe displacement or proptosis. Preoperative computed tomography demonstrated $13{\times}10{\times}5mm$-sized soft tissue mass. On March 2011, the mass was removed through an intraoral approach. On histopathological examination, the gross specimen consisted of a smooth, well-encapsulated and light yellowish solid mass, measuring $12{\times}7{\times}5mm$. Microscopically, it presented a typical manifestation of schwannoma with Antoni A area with Verocay body, and Antoni B area on H&E stain. The result of the immunohistochemical staining was positive for the S-100 protein. The patient had hypoesthesia of the nasal septum and vestibule in the postoperative period, and this finding confirmed that the internal nasal branch of infraorbital nerve was the nerve in which the schwannoma originated. Infraorbital schwannomas are very rare and must be included in the differential diagnosis of the orbital masses inferior to the eyeball. In the case of early diagnosis, the small-sized infraorbital schwannomas can be completely removed without any scar through an intraoral approach.

• 농업생명과학연구
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• 제46권4호
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• pp.129-139
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• 2012

마늘종의 영양학적 특성 및 생리활성 물질에 대한 기초자료를 확보하고자 생 마늘종과 데친 마늘종의 이화학적 성분을 비교 분석하였다. 생 마늘종의 수분은 $85.14{\pm}0.35%$, 조단백 및 조지방은 $0.79{\pm}0.26%$ 및 $2.96{\pm}0.03%$였으며 비타민 C는 생 마늘종이 $7.07{\pm}0.84mg/100g$으로 더 높았다. 총 페놀 및 플라보노이드 함량은 데친 마늘종에서 더 높아 각각 $17.89{\pm}1.46$ 및 $8.68{\pm}0.24mg/100g$이었다. 총 클로로필 함량은 생 마늘종이 $6.86{\pm}0.60mg/100g$이었으며 데친 마늘종에서는 $6.70{\pm}0.46mg/100g$으로 유의차가 없었다. Total pyruvate는 생 마늘종이 $24.63{\pm}1.59mM/g$으로 데친 마늘종에 비해 높았고 thiosulfinate는 생 마늘종이 $183.76{\pm}26.56mM/g$으로 유의적으로 높았다. 알리신 함량은 데친 마늘종이 생 마늘종에 비해 45%나 높게 측정되었다. 무기물 중 칼륨의 함량이 가장 높았으며, 총량은 생 마늘종에서 더 높았다. 마늘종의 생리활성 규명의 일환으로 생 마늘종과 데친 마늘종으로 물과 주정 추출물을 각각 제조하여 각 추출물의 총 페놀 및 플라보노이드 함량을 분석한 결과, 총 페놀 화합물은 $3.49{\pm}0.11{\sim}3.75{\pm}0.29mg/100g$으로 유의차가 없었고, 플라보노이드 함량은 $1.79{\pm}0.01{\sim}3.68{\pm}0.01mg/100g$으로 데친 마늘종의 물 추출물이 가장 높았다. ABTS 라디칼 소거능 측정 결과, 데친 마늘종 물 추출물의 소거능이 $85.09{\pm}0.28%$로 가장 높았다. 항균활성은 생 마늘종 물 추출물이 가장 높아 실험된 4종의 균주 모두에 항균활성이 있었으나 다른 추출물에서는 활성이 미약하거나 없었다.

• Toxicological Research
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• 제34권4호
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• pp.325-332
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• 2018

The mechanism of the previously reported antidiabetic effect of Basella alba is unknown. This study investigated the role of B. alba aqueous leaf extract in the modulation of inflammatory cytokines and islet morphology in streptozotocin-induced diabetic rats. Forty male Wistar rats, between 8 and 10 weeks old, were randomly divided into four groups (n = 10) and administered the following treatments: Healthy control (H-c) and Diabetic control (D-c) animals received normal saline 0.5 mL/100 g body weight daily, while Healthy Treatment (H-Ba) and Diabetic Treatment (D-Ba) rats received the plant extract 200 mg/kg body weight daily. All treatments were administered by oral gavage. Diabetes was induced in D-c and D-Ba rats by a single intraperitoneal injection of streptozotocin (55 mg/kg body). The body weight and fasting blood sugar (FBS) levels were recorded every week for 4 weeks, after which the rats were euthanized and samples collected for further analysis. After the experiment, FBS level was significantly reduced (p < 0.0001) in rats in the D-Ba group, but increased (p < 0.001) in rats in the D-c group. The absolute (H-c and H-Ba vs D-c, p < 0.05) and relative (D-Ba vs H-c, p < 0.05; D-Ba vs H-Ba, p < 0.005) weights of the pancreases were significantly higher after the experiment. The rats in the D-c group had significantly higher levels of serum interleukin-$1{\beta}$ (p < 0.001 vs H-c; p < 0.05 vs H-Ba and D-Ba) and monocyte chemotactic protein-1 (p < 0.0001), but lower levels of interleukin-10 (p < 0.05) in comparison with the other groups. Histopathological examination revealed severe interstitial congestion, reduced islet area (p < 0.0001), and increased islet cell density in the D-c group compared with those in the D-Ba group. From these findings, it was concluded that the aqueous extract of B. alba stimulates the recovery of beta-islet morphology in streptozotocininduced diabetic rats by modulating the peripheral production of inflammatory cytokines.

• Asian-Australasian Journal of Animal Sciences
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• 제26권5호
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• pp.654-660
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• 2013

Three Korean native steers ($779{\pm}24$ kg) fitted with duodenal cannulas were used in a $3{\times}3$ Latin square design to investigate the influence of oral administration of soluble proteins, intact casein (IC) and acid hydrolyzed casein (AHC), on gastro-intestinal hormone (GIH) secretion in the blood and pancreatic ${\alpha}$-amylase activity in the duodenum. Oral treatment consisted of a basic diet (control), IC (C+100% protein), or AHC (C+80% amino acid, 20% peptide) for 21 d. Blood and duodenum samples were collected for measurement of serum GI hormones, and pancreatic ${\alpha}$-amylase activity was determined at 900, 1030, 1330, 1630, and 1930 h after feeding on d 21 of treatment. The levels of serum cholecystokinin (CCK) and secretin in the IC treatment group were higher compared to the other treatment groups (p<0.05). In addition to the changes in CCK and secretin levels upon IC treatment, the pancreatic ${\alpha}$-amylase activity in the duodenum was higher in the IC group compared to the control diet group (p<0.05). The response of serum ghrelin to IC and AHC treatment was in accordance with the response of serum secretin. The level of peptide fragments flowing in the duodenum was higher in the IC treatment group than the other treatment groups (p<0.05). In conclusion, this study demonstrated that an increase in duodenal CCK and secretin upon IC oral administration increased pancreatic ${\alpha}$-amylase secretion. In addition, ghrelin may be associated with GI hormone secretion in Korean native steers.

• 한국수산과학회지
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• 제35권5호
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• pp.519-523
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• 2002

국내에서 양식되는 가시파래 (E. prolifera)의 효율적 이용과 새로운 기능성 식품소재로서 사용하기 위한 기초자료를 얻기 위해 가시파래의 수용성 다당을 추출 후 CPC와 음이온 교환수지로 분획하여 화학적 특성을 조사하였다. 가사파래를 열수로 3회 반복하여 추출하여 얻은 수용성 다당의 수율은 $23.7\%$였고 총당, 단백질, 황산기의 함량이 각각 $68.8\%$, $6.7\%$, $23.7\%$였다. 수용성 다당을 CPC처리하여 얻은 산성다당인 CPC-PS는 주 구성성분이 황산기, 우론산, rhamnose, xylose였으며 주요 구성당인 xylose : rhamnose : glucose의 몰비는 1 : 3.1 : 0.2 이었다. CPC-PS를 음이온 교환수지로 분획하였을 때 3개의 fraction (Fr-1, Fr-2, Fr-3)이 얻어졌으며 각 획분간의 화학적 조성상 큰 차이점 없었다. CPC-PS의 분자량은 620,000이었고, 이를 이온교환수지로 분획한 획분인 Fr-1은 710,000 ($84\%$), 90,000 ($14\%$), 70,000 ($2\%$), Fr-2는 510,000, Fr-3은 830,000 daltons으로 Fr-1을 제외한 나머지 획분은 단일피크로 대칭성을 나타내어 분자량이 균일함을 알 수 있었다. 그리고 이 획분들을 전기영동 하였을 때 Fr-1과 Fr-3은 단일 band를 나타내었다.

• 한국가금학회지
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• 제34권2호
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• pp.105-110
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• 2007

본 연구는 육계의 개방 계사에서 사육 밀도에 따라 고밀도(0.050$m^2$/수), 관행(0.066$m^2$/수), 저밀도(0.083$m^2$/수) 사육구로 구분하여 사육 밀도가 여름철 육계 생산성에 미치는 영향을 평가하고자 실시하였다. 공시계는 육계 초생추 Ross로서 684수를 이용하였으며, 5주간 사양 시험을 실시하였다. 기초 사료 영양소 함량은 사육 전기($0{\sim}3$주)에 ME 3,100 kcal/kg, CP 22.0%, 후기($4{\sim}5$주)에는 각각 3,100 kcal/kg, 20.0%로 하였다. 사육 밀도에 의한 육계의 체중은 5주령에 고밀도 처리구인 T1이 관행적인 T2와 저밀도구인 T3 처리구에 비해 유의적으로(P<0.05) 감소하였다. 사료 섭취량도 체중의 변화와 동일한 결과를 보였다. 사료 요구율은 관행적인 T2 처리구에서 유의적으로(P<0.05) 개선되었다. 음수 섭취량과 깔짚 수분 함수율은 시험 전 기간동안 처리구간에 통계적인 차이가 없었다. 혈청 성분의 분석결과에서는 total protein, cholesterol 및 albumin의 수치가 T3에서 낮은 경향이었으나 유의성은 인정되지 않았다. 본 연구 결과 육계의 사육 밀도 증가는 생산성을 감소시키며 개체에 스트레스를 증가시켜 폐사율의 증가와 도체 품질을 저하시킬 수 있는 가능성을 시사하였다.