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Case Report of Pressure Injury in Intracerebral Hemorrhage Patients Improved by Combining Radix Astragali Pharmacoacupuncture Solution during Antibiotic Treatment (항생제 치료 중 드레싱과 황기 약침액 도포를 병행하여 호전된 뇌출혈 환자 욕창 1례)

  • Geun Young Kim;Dabin Lee;Seon Uk Jeon;Han-Gyul Lee;Ki-Ho Cho;Sang-Kwan Moon;Woo-Sang Jung;Seungwon Kwon
    • The Journal of Internal Korean Medicine
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    • v.44 no.2
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    • pp.167-177
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    • 2023
  • Background: Pressure injuries are localized areas of damage to the skin and/or underlying tissue, usually over a bony prominence due to pressure. Cerebrovascular disease increases the risk of pressure injuries due to the immobility caused by physical paralysis. The general approach to managing a patient with pressure injuries should include pain relief, the treatment of the infection, optimizing nutritional intake, proper positioning, and contamination prevention. Nonetheless, the duration of treatment for pressure injuries varies from person to person. Case report: An 80-year-old female intracerebral hemorrhage patient developed a pressure injury. To improve the injury faster, a Radix Astragali pharmacoacupuncture solution was applied to the pressure sore. The pressure injury's width, length, and depth was assessed using a ruler, and the exudate amount and tissue types were assessed. The treatment was performed for 35 days. The rate at which the size of the pressure sore lessened increased since the Radix Astragali pharmacoacupuncture solution was applied to the pressure sore. In addition, the tissue type of the pressure injury improved, and the exudates decreased. There was no significant difference in the Pressure Ulcer Scale for Healing Tool 3.0, since the Radix Astragali pharmacoacupuncture solution was applied to the pressure injury. Conclusion: This clinical case study suggests that the Radix Astragali pharmacoacupuncture solution might be effective in speeding up the healing of pressure injuries.

A Study on Operational Design Domain Classification System of National for Autonomous Vehicle of Autonomous Vehicle (자율주행을 위한 국내 ODD 분류 체계 연구)

  • Ji-yeon Lee;Seung-neo Son;Yong-Sung Cho
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.22 no.2
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    • pp.195-211
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    • 2023
  • For the commercialization For the commercialization of autonomous vehicles (AV), the operational design domain (ODD) of automated driving systems (ADS) is to be clearly defined. A common language and consistent format must be prepared so that AV-related stakeholders can understand ODD at the same level. Therefore, overseas countries are presenting a standardized ODD framework and developing scenarios that can evaluate ADS-specific functions based on ODD. However, ODD includes conditions reflecting the characteristics of each country, such as road environment, weather environment, and traffic environment. Thus, it is necessary to clearly understand the meaning of the items defined overseas and to harmonize them to reflect the specific domestic conditions. Therefore, in this study, domestic optimization of the ODD classification system was performed by analyzing the domestic driving environment based on international standards. The driving environment of currently operating self-driving car test districts (Sangam, Seoul, and Gwangju) was investigated using the developed domestic ODD items. Then, based on the results obtained, the ranges of the ODDs in each test district were determined and compared.

Efficacy of intraosseous saline injection for pain management during surgical removal of impacted mandibular third molars: a randomized double-blinded clinical trial

  • Jawahar Babu. S;Naveen Kumar Jayakumar;Pearlcid Siroraj
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.23 no.3
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    • pp.163-171
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    • 2023
  • Background: Surgical extraction of impacted mandibular third molars is the most common procedure performed by oral surgeons. The procedure cannot be performed effectively without achieving profound anesthesia. During this procedure, patients may feel pain during surgical bone removal (at the cancellous level) or during splitting and luxation of the tooth, despite administration of routine nerve blocks. Administration of intraosseous (IO) lignocaine injections during third molar surgeries to provide effective anesthesia for pain alleviation has been documented. However, whether the anesthetic effect of lignocaine is the only reason for pain alleviation when administered intraosseously remains unclear. This conundrum motivated us to assess the efficacy of IO normal saline versus lignocaine injections during surgical removal of impacted mandibular third molars. The aim of this study was to assess the efficacy of IO normal saline as a viable alternative or adjunct to lignocaine for alleviation of intraoperative pain during surgical removal of impacted mandibular third molars. Methods: This randomized, double-blind, interventional study included 160 patients who underwent surgical extraction of impacted mandibular third molars and experienced pain during surgical removal of the buccal bone or sectioning and luxation of the tooth. The participants were divided into two groups: the study group, which included patients who would receive IO saline injections, and the control group, which included patients who would receive IO lignocaine injections. Patients were asked to complete a visual analog pain scale (VAPS) at baseline and after receiving the IO injections. Results: Of the 160 patients included in this study, 80 received IO lignocaine (control group), whereas 80 received IO saline (study group) following randomization. The baseline VAPS score of the patients and controls was 5.71 ± 1.33 and 5.68 ± 1.21, respectively. The difference between the baseline VAPS scores of the two groups was not statistically significant (P > 0.05). The difference between the numbers of patients who experienced pain relief following administration of IO lignocaine (n=74) versus saline (n=69) was not statistically significant (P > 0.05). The difference between VAPS scores measured after IO injection in both groups was not statistically significant (P >0.05) (1.05 ± 1.20 for the control group vs. 1.72 ± 1.56 for the study group) Conclusion: The study demonstrates that IO injection of normal saline is as effective as lignocaine in alleviating pain during surgical removal of impacted mandibular third molars and can be used as an effective adjunct to conventional lignocaine injection.

Analysis of enzyme activity changes caused by flooding stress in upland crops (침수 스트레스에 의한 밭작물의 효소활성 변화 분석)

  • Juhyung Shin;Byeonggyu Kim;Kihwan Kim;Tae-An Kang;Won-Chan Kim
    • Korean Journal of Environmental Biology
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    • v.40 no.3
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    • pp.341-351
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    • 2022
  • Among various environmental stresses, humid stress lacks mechanisms and biochemical understanding compared to drought, low temperature, and high salt stresses. The aim of this study was to investigate enzyme activity of field crops under humidity stress. Results of this study could be used as basic data for understanding humidity stress and early diagnosis. Growth and enzyme activities of sesame, perilla, red beans, sorghum, and beans as major field crops in Korea when flooded were investigated. It was confirmed that growths of both shoots and roots were retarded. In plants, anaerobic fermentation occurred due to flooding stress, which increased the activity of alcohol dehydrogenase (ADH) compared to the control group. Increases of reactive oxygen species (ROS) were also observed. All flooded plants showed increased peroxidase (POD) activity and lipid peroxidation. Their dyeing strength was darker than that of the control group, even in 3,3'-diaminobenzidine (DAB) staining. Since enzyme activity changes in plants appear relatively faster than changes in phenotype at the ground level, they could be used as biomarkers for early diagnosis of humidity stress in crops.

Spatial distribution of heterotrophic bacteria and the role of microbial food web in the northern East China Sea in summer (하계 동중국해 북부해역에서 종속영양박테리아의 분포 특성 및 미생물 먹이망의 역할)

  • Bomina Kim;Seok-Hyun Youn
    • Korean Journal of Environmental Biology
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    • v.41 no.1
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    • pp.89-100
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    • 2023
  • We investigated the spatial distribution of heterotrophic bacteria associated with different water masses in the northern East China Sea(ECS) in summer. The surface water masses were divided into the Changjiang Diluted Water (CDW) and high salinity water (HSW). In the CDW region, the concentrations of dissolved inorganic nitrogen (DIN) and chlorophyll-a (Chl-a), and micro Chl-a contribution were high; and bacterial abundance (BA) and ciliate abundance (CA) were also high. In the HSW region with relatively low DIN concentrations, Chl-a concentration and micro Chl-a contribution were low, but pico Chl-a contribution was increased compared to those in the CDW region. BA did not show any significant difference from the CDW region, but CA was decreased. BA showed a positive correlation with Chl-a concentration in the CDW region; however, it did not show a significant correlation with Chl-a concentration in the HSW region. The ratio of bacterial carbon biomass/phytoplankton carbon biomass was exponentially increased with a decrease in the Chl-a concentration. Compared to the past (1990-2000s), the surface phosphate concentrations and the size of dominant phytoplankton have recently decreased in the ECS. Considering this trend of nutrient decrease and miniaturization of the phytoplankton, our results indicate that changes in the strength of the oligotrophic water mass could alter the function of the microbial food web.

A Study on Metaverse Utilization and Introduction Strategies in College Education: Based on Step-by-step Metaverse Introduction Framework (대학 교육의 메타버스 활용 현황 및 도입 전략에 대한 연구: 단계별 메타버스 도입 프레임워크 개발을 바탕으로)

  • Son, Young Jin;Park, Minjung;Chai, Sangmi
    • Knowledge Management Research
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    • v.24 no.1
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    • pp.1-29
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    • 2023
  • The COVID-19 pandemic has accelerated digital transformation across all industries and daily life. Edutech is spreading in the education field, also bringing changes in university education. Non-face-to-face online-only classes at universities have spread after the COVID-19 pandemic physical distancing started. Online-only or real-time online classes showed diverse educational imitations. 'Metaverse' started to attract attention as a learning space and community activity support platform that may solve the limitations of online education and communication. It is time to prepare an introduction strategy for the actual application of education using metaverse. This study, first, by examining previous studies and cases of metaverse application, and second, establishing a metaverse introduction framework based on the technology lifecycle model and the innovation diffusion theory. Finally, we provide an introduction strategy in steps, a specialized introduction plan according to the main users is established and presented as a scenario. We expect that this study will provide the theoretical background of the new technology introduction and the spread of metaverse research. Also, we present an efficient introduction strategy, the basis for a service model, and a practical basis for the university's value-added strategy.

Emulsification of O/W Emulsion Using Natural Mixed Emulsifiers : Optimization of Emulsion Stability Using Central Composite Design-Reponse Surface Methodology (천연 혼합유화제를 이용한 O/W 유화액의 제조 : 중심합성계획모델을 이용한 유화안정성 최적화)

  • Seheum Hong;Cuiwei Chen;Seung Bum Lee
    • Applied Chemistry for Engineering
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    • v.34 no.3
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    • pp.299-306
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    • 2023
  • In this study, the O/W emulsification processes with the natural surfactants that were extracted from Medicago sativa L. and Sapindus saponaria L. as emulsifiers were optimized using the central composite design-response surface methodology (CCD-RSM). Herein, independent parameters were the amounts of mixed emulsifiers, the mixing ratio of natural emulsifiers (soapberry saponin/alfalfa saponin), and the emulsification time, whereas the reaction parameters were the emulsion stability index (ESI), mean droplet size (MDS), and antioxidant activity (DPPH radical scanvenging activity). Through basic experiments, the ranges of operation variables for the amount of mixed emulsifiers, the mixing ratio of natural emulsifiers, and the emulsification time were 12~14 wt%, 30~70%, and 20~30 min, respectively. The optimum operation variables deduced from CCD-RSM for the amount of mixed emulsifiers, the mixing ratio of natural emulsifiers, and the emulsification time were 13.2 wt%, 44.2%, and 25.8 min, respectively. Under these optimal conditions, the expected values of the ESI, MDS, and antioxidant activity were 88.7%, 815.5 nm, and 38.7%, respectively. And, the measured values of the ESI, MDS, and antioxidant activity were 90.6%, 830.2 nm, and 39.6%, respectively, and the average experimental error for validating the accuracy was about 2.1%. Therefore, it was possible to design an optimization process for evaluating the O/W emulsion process using CCD-RSM.

Conservation Treatment of the Rickshaw in the Daegu Modern History Museum Collection (대구근대역사관 소장 인력거 보존처리)

  • Seo Yeonju;Lee Uicheon;Park Junghae;Lee Yeongju;Kim Soochul
    • Conservation Science in Museum
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    • v.29
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    • pp.33-46
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    • 2023
  • Modern and contemporary cultural assets are defined as a collective term for tangible historical and cultural assets produced in the modern and contemporary period (around the opening of Joseon to the present) in Korea. Among them, rickshaws have been used as a major means of transportation for about 40 years since the opening of the ports in Joseon. The repair process for rickshaws divides the rickshaw into three parts, namely the body, the cover, and the wheels, applying a plaster treatment process by referring to the outcomes of the condition assessment and material analysis for the metal, wood, fiber, and paint used. Overall, the repair process is carried out through dry/wet cleaning, joining, stabilization, reinforcement of damaged parts, and other restoration treatments, which reveal metal decorations and patterns on the scaffolding (flowers, arabesque patterns, etc.) that were previously not observable with the naked eye, while also adding to the stability of the artifact. In addition, props were produced to ensure the artifact's safe exhibition.

The Effects of Coupled Open Innovation of Small- and Medium-sized Enterprises on Firm Performance: Focusing on R&D and Non-R&D Innovation Cooperation Activities (중소기업의 결합형 개방형 혁신이 기업성과에 미치는 효과: R&D 및 R&D 이외의 혁신협력활동을 중심으로)

  • Ji-Hoon Park;Jungwoo Lee
    • Knowledge Management Research
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    • v.23 no.4
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    • pp.177-205
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    • 2022
  • Small- and medium-sized enterprises (SMEs) have strong incentives to engage in open innovation to enhance innovation efficiency and effectiveness due to their 'liability of smallness.' Previous research examined the performance effects of various open innovation practices, but whether coupled open innovation practices positively affect SMEs' firm performance is somewhat controversial. To resolve the issue, this study examined the effects of coupled open innovation activities on SMEs' firm performance using Heckman's two stage model to control endogeneity of the firms' self-selection bias in open innovation engagement. This study used the Korean Innovation Survey (KIS) 2020 collected by the Science and Technology Policy Institute (STEPI), and tested the effects of SMEs' coupled open innovation activities, R&D and non-R&D cooperation, on their innovative and financial performance indicators. The results showed that SMEs' R&D cooperation positively affects the new-to-market (NTM) product innovation only. Moreover, SMEs' non-R&D cooperation has positive effects on the product innovation, business process innovation, new-to-the-market product innovation, and new-to-firm (NTF) product innovation. However, the results showed that both R&D and non-R&D innovation cooperation activities have no significant effects on SMEs' financial performance indicators. This study contributes to research on SMEs' open innovation and provides insights for SMEs' managers and policymakers.

A Case Study of the CR based e-Marketplace Implementation in Nuclear Parts Company (CR 기반의 원전부품제조업체 e-Marketplace 구현)

  • Jung, Lee-Sang;Ha, Chang-Seung;Lee, Seok-Yong
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.8
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    • pp.145-152
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    • 2009
  • Manufacturer's competitiveness in the MRO industry, which is to stimulate the growth of the business-to-business e-commerce market, has recently become more important. A nuclear parts manufacturer was supplying products based on irregular demand from clients which differs from ordinary MRO business practices. The reason for this is the Nuclear Parts Manufacturer has fallen behind the e-commerce performance of other industries, and they lack global competitiveness due to the low efficiency of the individual companies within it. In this study, we developed an MRO based a-Marketplace system to minimize repetitive ordering of raw materials, lack of reusability and inefficiency of transaction processing which was a result of the former legacy business practice, In order to accomplish the purpose of this study, we implemented a web based automated CR system which considered the characteristics of the nuclear parts manufacturing: the system has sub modules such as ordering, product management, transaction management, warehousing and raw material handling. As a consequence of the system implementation, H corporate successfully automated ordering of raw materials, quotation processing and inventory management compared to the legacy business process, achieving increased efficiency by reducing wasteful resources.