• Title/Summary/Keyword: S-locus

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A Study on the relationship of family support and personality with quality of life in the Patients receiving radiotherapy for breast cancer (방사선 치료를 받는 유방암 환자의 가족지지와 성격이 삶의 질에 미치는 영향)

  • Rhee Dong Soo;Rou Jae Man;Jee Dong Hwa;Kim Jong Deok;Noh Young Hee;Han You Jeong;So Hyang sook
    • The Journal of Korean Society for Radiation Therapy
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    • v.14 no.1
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    • pp.155-164
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    • 2002
  • This descriptive correlation study was undertaken in order to investigate the relationship of family support and personality with quality of life in patients receiving radiotherapy for breast cancer and to provide basic data to help them improve a better quality of life. This subjects for this study were 74 out-patients undergoing a radiation therapy at C hospital in Kwang-Ju. The data were obtained using a convenience sampling technique. The tool of this study were Ro's qualify of life scale, Kang's family support scale and Wallston & others health locus of control scale. The data were analyzed using a SAS program for percentage, mean, standard deviation, Pearson Correlation Coefficient, GLM. The results were as fellows: 1. The total average score of the quality of life of the subjects was 137.22 (minimum score 38-maximum score 227), item mean score(range 1-5) was 3.15. The total average score of the family support of the subjects was 40.38(minimum score 21-maximum score 47), item mean score(range 1-5) was 3.69. The total average score of health locus of control of the subjects was 42.47(minimum score 28-maximum score 59), item mean score(range 1-6 was 3.69. 2. The results of the analysis of the relationship between the quality of life scores and the health locus of control were as follows : the total average score of the qualify of life of internal locus of control scale was 133.50, he total average score of the quality of life of external locus of control scale was 138.41. 3. There was positive correlation between the health locus of control and the quality of life(r=0.0722, p=0.5413). 4. There were significant positive correlation between family support and quality of life(r=0.2328, p=0.0399). The results of the analysis of the relationship between the each factor in the quality of life scores and family support were as fellows : There were significant difference between the self esteem factor(r=0.2974, p=0.0124), relationship with family factor(r=0.2657, p=0.0241)

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Identification and Characterization of Novel Sequences of ev21-K Locus for Feather-Sexing in Chickens

  • Eun Jung Cho;Sea Hwan Sohn
    • Korean Journal of Poultry Science
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    • v.51 no.2
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    • pp.117-125
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    • 2024
  • This study aimed to find genetic markers for breed-independent identification of early- and late-feathering chickens. We explored the novel sequences of the ev21-K locus associated with late-feathering and investigated its characterization. Additionally, the genetic transmission pattern of the identified sequences were investigated to understand its potential application in auto-sexing lines. A total of 707 chickens from 5 chicken breeds were employed for the study. The ev21-K locus was identified through a comparative analysis of the ev21 gene and the K gene related to feather development. For analysis of identified loci, specific primers for the target sequences were prepared and polymerase chain reaction (PCR) was performed to obtain the products, and then their nucleotide sequences were analyzed. Crossbreeding tests of early-feathering and late-feathering chickens were conducted to examine the genetic transmission patterns of the identified sequences. The results showed that the identified 230 bp ev21-K locus, which named as ev21-related K specific sequences were 99% homology with the ev21 gene. PCR analysis confirmed its presence exclusively in late-feathering chickens. Comparative analyses across tissues, breeds, and ages demonstrated the sequences consistency in identifying late-feathering chickens. Genetic transmission patterns were investigated through crossbreeding tests, revealing sex-linked inheritance and consistent segregation with feathering phenotypes. The inheritance patterns of the ev21-related K specific sequences demonstrated that this locus follows the typical Mendelian inheritance pattern as a dominant gene. In conclusion, the novel sequences of ev21-K locus were a reliable molecular marker for identifying early- and late-feathering chickens across breeds.

Individual-breed Assignment Analysis in Swine Populations by Using Microsatellite Markers

  • Fan, B.;Chen, Y.Z.;Moran, C.;Zhao, S.H;Liu, B.;Yu, M.;Zhu, M.J.;Xiong, T.A.;Li, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.11
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    • pp.1529-1534
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    • 2005
  • Individual-breed assignments were implemented in six swine populations using twenty six microsatellites recommended by the Food and Agriculture Organization and the International Society for Animal Genetics (FAO-ISAG). Most microsatellites exhibited high polymorphisms as shown by the number of alleles and the polymorphism information content. The assignment accuracy per locus obtained by using the Bayesian method ranged from 33.33% (CGA) to 68.47% (S0068), and the accumulated assignment accuracy of the top ten loci combination added up to 96.40%. The assignment power of microsatellites based on the Bayesian method had positive correlations with the number of alleles and the gene differential coefficient ($G_{st}$) per locus, while it has no relationship to genetic heterozygosity, polymorphism information content per locus and the exclusion probabilities under case II and case III. The percentage of corrected assignment was highest for the Bayesian method, followed by the gene frequency and distancebased methods. The assignment efficiency of microsatellites rose with increase in the number of loci used, and it can reach 98% when using a ten-locus combination. This indicated that such a set of ten microsatellites is sufficient for breed verification purposes.

Health Locus of Control in Indonesian Women with Breast Cancer: a Comparison with Healthy Women

  • Iskandarsyah, Aulia;de Klerk, Cora;Suardi, Dradjat R.;Sadarjoen, Sawitri S.;Passchier, Jan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.21
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    • pp.9191-9197
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    • 2014
  • The aims of this study were to assess whether Indonesian women with breast cancer havea higher external health locus of control (HLC) than healthy women, and to explore the association between HLC and symptoms of anxiety and depression. In this study, 120 consecutive women with breast cancer were recruited at the outpatient surgical oncology clinic at the Hasan Sadikin Hospital in Bandung. One hundred and twenty two healthy women were recruited from the Bandung area as controls. A standard demographic form, Form C of the Multidimensional Health Locus of Control, as well as the Hospital Anxiety and Depression Scale and patients' medical records were used. Data were analyzed using descriptive statistics, t-test, Pearson's correlation, MANOVA and multiple linear regressions. Women with breast cancer had higher scores on all external HLC subscales, i.e. chance, doctor, powerful others and God, and lower internal HLC compared to healthy women. High God LHC scores were associated with a high level of anxiety (${\beta}=0.21$, p<0.05), whereas none of the HLC subscales were associated with depression. Our results suggest that women with breast cancer tend to have high external HLC, while healthy women tend to have high internal HLC. A strong belief in an external source of control, i.e. God, might be negatively associated with patient emotional adjustment. Further research is needed to give an insight into the direction of this association.

Locus of Control and Eating behavior of Obese Middle School Girls (비만 여중생의 건강통제위 성격과 섭식행동)

  • Kim Shin-Jeong;Kim Sook-Young;Moon Sun-Young;Gu Hyun-Kyung;Choi Yong-Hee
    • Child Health Nursing Research
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    • v.9 no.2
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    • pp.123-130
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    • 2003
  • Purpose: The purpose of this study was to investigate the relationship between health locus of control(HLOC) and eating behavior in obese middle school girls. Method: The sample consisted of 170 obese middle school girls in Seoul. Result: 1. The average scores of HLOC were HLOC-Internal ; 4.11, HLOC-External ; 2.45, HLOC-Chance ; 2.09. 2. The average scores of eating behavior factors were Disinhibition ; 2.69, Dietary Restraint ; 2.67, Hunger ; 2.55. 3. The HLOC-Internal and eating behavior(dietary restraint and hunger) were correlated positively. The HLOC-Chance and disinhibition was correlated positively. But HLOC-Chance and dietary restraint was correlated negatively. The HLOC-External and eating behavior(dietary restraint, disinhibition and hunger) were correlated positively. 4. There was not a significant difference in HLOC depending on the demographic characteristics(grade, degree of obesity, father & mother's body shape, existence of obese sibling). There were significant differences in HLOC-Internal and HLOC-External according to thinking about oneself who is obese or not. 5. There was not a significant difference in eating behavior depending on the demographic characteristics(grade, degree of obesity, father & mother's body shape, existence of obese sibling, perception of oneself as a obese). Conclusion: This study has shown a correlation between HLOC and eating behavior. As a result of these findings, clinical and school nurses should be involved in management and counselling of obese girls concerning individual health locus of control and eating behavior.

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Study for comparison with male & female rat locus coeruleus using confocal laser scanning microscopy (공초점현미경을 이용한 암수 흰쥐 청색반점의 비교연구)

  • Park, Il-kwon;Song, Chi-won;Lee, Kyung-youl;Kwon, Hyo-jung;Kim, Moo-kang;Lee, Kang-iee;Jeong, Young-gil;Lee, Nam-seob;Ha, Kwon-soo
    • Korean Journal of Veterinary Research
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    • v.40 no.3
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    • pp.451-461
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    • 2000
  • The locus coeruleus(LG) is known to be observed a sexual dimorphism in rat CNS. LC is the largest collections of norepinephrine(NE)-containing neurons in the mammalian brain. Especially in rat, all LC neurons contained NE unlike other mammalians, so that specific reactions were found in the tyrosine-hydroxylase(TH) immunoreactive neurons. Sexual dimorphism of rat LC has affected by genes before sex hormone appeared, thereafter affected by sex hormones. In these day, many scientists founded morphological differences between male and female LC morphology, but differences of entire structure was not founded. Thus we investigated sex differences of the LC neuron's morphology in rat by three-dimensional(3-D) reconstruction using Confocal laser scanning microscopy(CLSM). We reported that neuron's shape was relatively-large multipolar neurons and neuron's processes in dorsal LC proceeded to ventral direction in the male and female rat. Male had a longer anterior-posterior length than female had in dorsal LC. In addition to middle-LC, male rat's LC had a more thicker posterior region but had not viewed in a previous study. In reverse, female rat's LC had a thicker anterior region like a previous study. This results using 3-D reconstruction by CLSM showed that the male's LC was more wide-ranging than female's relatively.

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Related factors of late middle aged women's cancer preventive behaviors in local churches (지역교회 중년여성의 암 예방행위 관련요인)

  • Park, Geum-Ja;Jo, Eun-Joo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.8
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    • pp.4999-5008
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    • 2014
  • This study was conducted to identify the factors related to the cancer preventive behaviors of middle aged women. The data was collected from October $1^{st}$ 2012 to February $10^{th}$ 2013 from 114 middle aged women in four churches in B city. As a result, there were significant differences in the cancer preventive behaviors according to cancer preventive education, concerns about cancer information and the utilization of cancer information. The cancer preventive behaviors were weakly related to the internal health locus of the control, chance health locus of the control and self-esteem. In addition, there was moderate correlation between the cancer preventive behaviors and the external health locus of the control. Meaningful variables that explain the cancer preventive behaviors were the external health locus of the control, self-esteem, cancer preventive education in that order. The total explanation power was 25.3% and the external health locus of the control has most explanation power. In conclusion, it is necessary to develop nursing intervention and health education for middle aged women to raise the internal health locus of the control and self-esteem, and encourage attending cancer preventive education to improve the preventive behaviors against cancer.

Family Linkage Analysis of CCM1 Locus on Chromosome 7q in Familial Cavernous Malformation (가족성 해면혈관종에서 염색체 7q CCM1 염기서열의 가족간 연관성 분석)

  • Sim Ki-Bum;Lee Chang Sub;Kim Seung-Ki;Wang Kyu-Chang;Kim Young-Im;Cho Byung-Kyu
    • Toxicological Research
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    • v.21 no.2
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    • pp.135-140
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    • 2005
  • Although the pathogenesis of cerebral cavernous malformation (CCM) is unknown, a familial predisposition has been recognized, with up to $55\%$ of patients having an affected relatives. Genetic linkage studies have recently mapped a gene causing CCM to a segment of the long arm of chromosome 7 (7q). We report herein a genetic linkage analysis conducted on a Korean three generation family with CCM. It's first report in Korean family. A Korean family in which one member had undergone surgery for ubtracerebrak hematoma (ICH) and confirmed the CCM, was evaluated. They were examined clinically (n=18) and by magnetic resonance (MR) imaging (n=10). Polymorphic markers (D7S1813, D7S1789) spanning the CCM1 locus on 7q were genotyped by the polymerase chain reaction and analysis of linkage was performed in this family (n=17). Six had multiple lesions on brain MR image, one of them being symptomatic, and five were asymptomatic. Seven remaining members were asymptomatic and refused MR image study. One had died of ICH from presumed CCM. Analysis of the pedigree was consistent with an autosomal dominant pattern of inheritance. All affected patients were linked to CCM1. Linkage to CCM1 can account for inheritance of CCM in this family. They had some striking features with a low clinical penetrance and the presence of multiple lesions. These findings have implications for genetic testing of this disorder and represent an important step toward identification of the gene responsible for the pathogenesis of this disease.

Study on the Yield Locus of Aluminum Alloy Sheet Using Biaxial Cruciform Specimens (2축 십자형 시편을 이용한 알루미늄 합금 판재의 항복곡면에 대한 연구)

  • Shin, H.D.;Park, J.G.;Park, C.D.;Kim, Y.S.
    • Transactions of Materials Processing
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    • v.18 no.5
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    • pp.416-421
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    • 2009
  • The applications of the aluminum alloy sheets to the auto-body panels are dramatically increasing for weight reduction of the automobiles. However, low formability of the aluminum alloy sheet compared to the steel sheet can be obstacles in tool manufacturing processes. Therefore, many of yield criteria for the anisotropic materials such as the aluminum alloy sheet have been observed. In this study, the biaxial tensile test and FLD test for the aluminum alloy sheet are performed. The results are compared with Hill's 1948 and Hill's 1990 models by means of theoretical predictions. Finite element analysis was also performed using the proposed method for the real panel.

Study on the Yield Locus of Aluminum alloy sheet Using Biaxial Cruciform Specimens (2축 십자형 시편을 이용한 알루미늄 합금 판재의 항복곡면에 대한 연구)

  • Shin, H.D.;Park, J.G.;Park, C.D.;Ro, H.C.;Youn, K.T.;Lim, H.T.;Kim, Y.S.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2009.05a
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    • pp.164-167
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    • 2009
  • The applications of the aluminum alloy sheets to the auto-body panels are dramatically increasing for weight reduction of the automobiles. However, low formability of the aluminum alloy sheet compare to the steel sheet can be obstacles in tool manufacturing process. Therefore, much of yield criteria for the anisotropic material such as the aluminum alloy sheet have been observed. In this study, the biaxial tensile test and FLD test for the aluminum alloy sheet are performed. The results are compared with Hill's 1948 and Hill's 1990 model by means of theoretical predictions. Finite element analysis also performed using the proposed method for the real panel.

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