• Korean Journal of Pharmacognosy
• /
• v.29 no.4
• /
• pp.402-412
• /
• 1998

This study was attempted to investigate the effect of 'Angelicae gigantis Radix extract (AG.EX.)' and 'Angelicae acutilobae Radix extract (AA.EX.)' on the activities of GOT, GPT and alkaline phosphatase (A1.P), the contents of total cholesterol in serum of $CCl_4$ and D-galactosamine intoxicated rats, and the weight change ratio of body, liver and spleen in $CCl_4-intoxicated-rats$ by administering the extract of 300 and 500 mg/kg P.O.. Significant test was performed by comparision with the biochemical values between intoxicated-control group and extract-administered group. The activities of s-GOT, s-GPT and the contents of total cholesterol elevated by $CCl_4-intoxication$ were significantly decreased in all dose (300, 500 mg/kg) of Angelicae gigantis Radix-water extract (AG.WEX.) and alcohol extract (AG.AEX), and Angelica acutilobae Radix-water extract (AA.WEX.) and alcohol extract (AA.AEX.), respectively, as compared with the control group. And administered group of 300 mg/kg showed more significant decreasing effect than 500 mg/kg, and more significantly decreased in water extract of AG.EX. and ethanol extract of AA.EX. But in the activities of s-A1.P. inhibition effect were significantly decreased only in a dose of 300 mg/kg of AA.WEX. and AA.AEX. The activities of s-GOT and s-GPT elevated by D-galactosamine were not decreased in all samples, as compared to intoxicated-control group. But the activities of s-Al.p was significantly decreased as compared with control groups, in all samples and administration of 300 mg/kg was more significantly decreased than 500 mg/kg. The contents of total cholesterol remarkably decreased than the normal groups by D-galactosamine intoxication was not recovered in all samples. The increasing rate of the body weight increased by $CCl_4-intoxication$ were not decreased than the $CCl_4-control$ group in all sample groups. The increasing rate of liver weight increased by $CCl_4-intoxication$ were significantly decreased in 300 mg/kg of AA.AEX.AG.WEX. and AA.WEX., respectively, as compared with $CCl_4-control$ group.

• Food Science of Animal Resources
• /
• v.26 no.3
• /
• pp.386-393
• /
• 2006

The effects of Curcuma extract Solomon's seal (Polygonatum odoratum var. pluriflorum), and maltodextrose on acute hepatotoxicity in Sprague-Dawley (SD) rats were investigated. Acute hepatotoxicity was induced by 0.5 mL of carbon tetrachloride ($CCl_4$) per kg of SD rats, which was injected to them before administration of Curcuma extract or both Solomon's seal (Polygonatum odoratum var. pluriflorum) and maltodextrose mixtures. SD rats dose with Curcuma extract of 4 mg or 40 mg per kg per day significantly (p<0.05) reduced the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALKP) after 7 days compared to the controls dose with water. Treatments of Curcuma extract with 4 mg per kg per day in SD rats significantly (p<0.05) reduced aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALKP) to 78.0%, 82.6%, and 76.3% after 7 days compared to the controls, respectively. The levels of AST and ALT in SD rats dose with both Solomon's seal (Polygonatum odoratum var. pluriflorum) and maltodextrose mixtures or either alone had no significantly different (p>0.05) compared to the controls. Treatments of Curcuma extract combined with Solomon's seal (Polygonatum odoratum var. pluriflorum) and maltodextrose mixtures was 'liked more' to the sensory scores for odor and flayer compared to the controls. It was considered that Curcuma extract combined with both Solomon's seal (Polygonatum odoratum var. pluriflorum) and maltodextrose mixtures could be used to functional food for enhancement of health and consumer acceptance.

• Journal of the Korean Dietetic Association
• /
• v.8 no.4
• /
• pp.333-341
• /
• 2002

Obesity, a state of having excessive body fat enough to attack one's health, is most blamed for causing chronical degenerative illness such as hypertension, diabetes mellitus as well as arteriosclerosis. According to many studies, the program for the weight control was the most demanded at the worksites. This study was designed to investigate the correlation between the degree of obesity and blood parameters of the employees at the worksites. The results of periodic medical examination for 571 employees(male: 418, female: 153) were analyzed; Age, BMI, systolic blood pressure(SBP), diastolic blood pressure(DBP), hemoglobin(Hb), fasting blood sugar(FBS), total-cholesterol(TC), serum glutamic oxaloacetic transaminase (sGOT), serum glutamic pyruvic transaminase(sGPT) and $gamma$-glutamyl transpeptidase($gamma$-GTP). Pearson correlation coefficient was used to find out the correlation between BMI and each blood parameters. In the case of male, 27.3% of the subjects were over-weight. The subject's age and their blood levels of uric acid, FBS, sGOT and sGPT did not show any significant difference regardless of BMI's, while SBP, DBP, Hb, TC and $gamma$-GTP levels of the overweight group were significantly higher than those of normal group. In the case of female, 9.2% of the subjects were over-weight. This study shows that the implementation of weight control program is required at the worksites

• Korean Journal of Pharmacognosy
• /
• v.26 no.4
• /
• pp.368-376
• /
• 1995

The leaf of Phyllostachys bambusoides S. et Z. (Gramineae) has been used in traditional herbal medicine as a antipyretics, antitussives and antidiuretcs, etc, in Korea, China and Japan. In order to investigate the effects on antilipoperoxidation and liver protective effect, the leaf of Phyllostachys bambusoides S. et Z. was extracted by water and then fractionated with butanol. The water extract and BuOH soluble fraction strongly exhibited antilipoperoxidatant effect in rat liver homogenate intoxicated with $CCl_4$. The BuOH fraction significantly suppressed the increases of s-GOT, s-GPT and s-LDH activities in injuried rats induced by $CCl_4$. And the BuOH fraction inhibited significantly the decrease of the body weight and showed the antilipoperoxidatant effect in liver and kidney in $CCl_4$ intoxicated rats.

• Journal of Korean Elementary Science Education
• /
• v.21 no.2
• /
• pp.201-212
• /
• 2002

This paper aims to find out how did elementary students understand scientific units in science textbooks. The subjects were 191 students of the 6th grade from 7 elementary schools in 3 different areas, consisting of 70 from 4 village schools of, 64 from 2 town schools of Gyeongnam province, and 57 from one city school in Ulsan Metro City. A test was developed based on the analysis of scientific units in the science textbooks and teacher's manuals constructed according to the 6th and 7th National Science Curriculum. The understanding of elementary students' on the scientific units(Temperature, Length, Weight, Volume, Speed, Plane Angle) were surveyed. The result are as follows: Regarding the temperature unit, the students generally well understand why to measure and how to read temperature, but had some problem in recording it, in confusion with the plane angle sign. As for the length unit, they obtained high scores in understanding the purpose of measuring length as well as recording and reading it. Which indicates that they are well aware of and use the unit appropriately. With respect to the weight unit, they got high scores in reading and recording weight, which means most students have no problem using the unit. However, it was found that they do not understand why to use the plate balance scale. The volume unit was one in which the students got relatively lower scores. They do not perceive the object of using a scale cylinder and confuse it with a device of length measurement. The unit of speed is the most difficult one for children's of science to understand, presumably, because it is an derived unit from two basic units. It is also assumed that the students got the highest score in the plane angle unit because they studied the unit immediately before the test. From the children's understanding of science units above the teacher's understanding and teaching methods presumed to play a major role for children to understand and use the science units properly.

• Nutritional Sciences
• /
• v.5 no.2
• /
• pp.53-59
• /
• 2002

This study was conducted to examine the effects of dietary sources of fatty acids and protein on serum protein profiles, hepatic functional enzyme activities, mammary tumor incidence and tumor weight in 7, 12-dimethylbenz($\alpha$)anthracene (DMBA)-treated rats. The sources of dietary fatty acids were 18n6 (rich in linoleic acid), 18n3 (rich in linolenic acid) and 22n3 (rich in DHA) : sources of dietary protein were casein (C) and soy protein isolate (S). mammary tumors (MTs) were chemically induced by DMBA (9 mg/100 g body weight) which was gastrically intubated at 7 weeks of age. Each experimental diet was given for the following 25 weeks. Casein-fed rats (group C) exhibited significantly higher levels of weight gain and FER (food efficiency ratio) than did group S. Group C showed higher levels of serum protein and globulin, and higher albumin/globulin (A/G) ratios than group S. Liver functional enzyme activities (GOT, GPT, ALP, LDH, $\gamma$-GT) and LDH/GOT ratios were not influenced by dietary protein. GPT activity was lower in the group given 18n3, and ALP activity was lower in the group given 18n6. The incidence and total number of MTs appeared to be lower in the group given 22n3 than in the group given 18n3 or 18n6, even though the average weight of MTs was highest in the group given 22n3, The average weight of MTs was higher in the C group than in the S group. MT incidence had a positive correlation with LDH activity and LDH/GOT ratio. The average weight of MTs had a negative correlation with serum albumin levels and A/G ratios, and a positive correlation with ALP activity. This research suggests that the measurement of serum protein profiles and liver functional enzyme activities may be utilized to monitor the development of mammary tumors.

• Journal of Acupuncture Research
• /
• v.30 no.3
• /
• pp.27-38
• /
• 2013

Objectives : This study was designed to evaluate patient satisfaction of Korean medicine therapy using treatment tool by psychological type. Methods : 48 subjects were participated in this study. Before a treatment, we analyzed a patient's phychological type first by using a questionnaire. And then we divided 3 groups which were called a rational sympathy module group, emotional sympathy module group, control group. Manner of medical consultation according to patient's phychological type was carried out in all groups. After all treatment, we conducted a survey about medical service perception index, patient happiness index, medical satisfaction index. To evaluate a satisfaction degree, we analyzed results of survey statistically. Results : The results of the analysis, both rational sympathy module group and emotional sympathy module group got a higher score than control group statistical significantly on medical service perception index. Emotional sympathy module group got a higher score than control group statistical significantly on patient happiness index and medical satisfaction index. But rational sympathy module group only had a higher tendency than control group on patient happiness index and medical satisfaction index. Emotional sympathy module group got a higher score than rational sympathy module group on medical service perception index, patient happiness index and medical satisfaction index. Conclusions : Korean medicine therapy using treatment tool by psychological type consisted of patient's phychological type questionnaire and manner of medical consultation could improve a patient's satisfaction. It was more effective in emotional sympathy module group than rational sympathy module group.

• The Journal of Korean Physical Therapy
• /
• v.9 no.1
• /
• pp.81-87
• /
• 1997

Although most of Korean PT professors and clinical lecturers has been thought the importance of the PT student's clinical practice, there has got a lot of training problems in clinical field. As the result, of our survey study pointed out trouble of the (1) training duration (2) training credits (3) training evaluation (4) training workbook (5) training fee (6) training hospital numbers and (7) training quality etc, in Korean today's situation. So we suggest the Internship-training system for above half a year after student has got a PT licence, as a desired training model.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 2007.10a
• /
• pp.300-301
• /
• 2007

In this study, it is investigated that sheet characteristics of high strength steel sheets and effect of springback. High strength steel sheets has got attention in automobile industry of high strength and high formability. Springback is a common phenomenon in sheet metal forming, caused by the elastic recovery of the internal stresses after removal of the tooling. However, the information in deformation behavior of high strength steel sheets, including bending and sheet characteristics and springback, is not enough until now. In this research, the V-bending experiment and analysis have been done to obtain the information of springback of high strength steel sheets. Tensile test for high strength steel sheets was done to got tensile properties of elastic modulus and flow stress of the material. It analyzed springback according to the sheet characteristics with using roll-forming model. FE-Simulation used DEFORM-$3D^{TM}$.

• Journal of Food Hygiene and Safety
• /
• v.24 no.3
• /
• pp.285-290
• /
• 2009

This study aimed to investigate the protective effect of Solanum nigum Linne total extract (SNT), Solanum nigum Linne leaf extract (SNL), Solanum nigum Linne root extract (SNR) on liver injury induced by Lipopolysaccharide(LPS) in Sprague-Dawley rats. SNT, SNL, SNR of 100 mg/kg concentration was intraperitoneally administered into rats at dose of 1.5 ml/kg for 20 days. on the day 1.5 ml/kg of LPS was injected. Four hours later, they were anesthetization with ether and dissected. Glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) were measured in serum and superoxide dismutase (SOD), catalase and glutathione peroxidase (GPX) were measured in liver homogenate. SNT, SNL, SNR extract inhibited GOT and GPT activities in LPS-induced rats, whereas increased SOD, Catalase and GPX activity in liver tissue of LPS-induced rats. These suggested that SNT, SNL, SNR could be used for functional beverage.