• Title/Summary/Keyword: S/N Ratio(Signal to Noise Ratio)

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Single-Protein Molecular Interactions on Polymer-Modified Glass Substrates for Nanoarray Chip Application Using Dual-Color TIRFM

  • Kim, Dae-Kwang;Lee, Hee-Gu;Jung, Hyung-Il;Kang, Seong-Ho
    • Bulletin of the Korean Chemical Society
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    • v.28 no.5
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    • pp.783-790
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    • 2007
  • The immobilization of proteins and their molecular interactions on various polymer-modified glass substrates [i.e. 3-aminopropyltriethoxysilane (APTS), 3-glycidoxypropyltrimethoxysilane (GPTS), poly (ethylene glycol) diacrylate (PEG-DA), chitosan (CHI), glutaraldehyde (GA), 3-(trichlorosilyl)propyl methacrylate (TPM), 3'-mercaptopropyltrimethoxysilane (MPTMS), glycidyl methacrylate (GMA) and poly-l-lysine (PL).] for potential applications in a nanoarray protein chip at the single-molecule level was evaluated using prismtype dual-color total internal reflection fluorescence microscopy (dual-color TIRFM). A dual-color TIRF microscope, which contained two individual laser beams and a single high-sensitivity camera, was used for the rapid and simultaneous dual-color detection of the interactions and colocalization of different proteins labeled with different fluorescent dyes such as Alexa Fluor® 488, Qdot® 525 and Alexa Fluor® 633. Most of the polymer-modified glass substrates showed good stability and a relative high signal-to-noise (S/N) ratio over a 40-day period after making the substrates. The GPTS/CHI/GA-modified glass substrate showed a 13.5-56.3% higher relative S/N ratio than the other substrates. 1% Top-Block in 10 mM phosphate buffered saline (pH 7.4) showed a 99.2% increase in the blocking effect of non-specific adsorption. These results show that dual-color TIRFM is a powerful methodology for detecting proteins at the single-molecule level with potential applications in nanoarray chips or nano-biosensors.

A Study of the Exclusive Embedded A/D Converter Using the Microprocessor and the Noise Decrease for the Magnetic Camera (마이크로프로세서를 이용한 자기카메라 전용 임베디드형 AD 변환기 및 잡음 감소에 관한 연구)

  • Lee, Jin-Yi;Hwang, Ji-Seong;Song, Ha-Ryong
    • Journal of the Korean Society for Nondestructive Testing
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    • v.26 no.2
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    • pp.99-107
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    • 2006
  • Magnetic nondestructive testing is very useful far detecting a crack on the surface or near of the surface of the ferromagnetic materials. The distribution of the magnetic flux leakage (DMFL) on a specimen has to be obtained quantitatively to evaluate the crack. The magnetic camera is proposed to obtain the DMFL at the large lift-off. The magnetic camera consists of a magnetic source, magnetic lens, analog to digital converters (ADCs), interface, and computer. The magnetic leakage fields or the distorted magnetic fields from the object, which are concentrated on the magnetic lens, are converted to analog electrical signals tv arrayed small magnetic sensors. These analog signals are converted to digital signals by the ADCs, and are stored, imaged, and processed by the interface and computer. However the magnetic camera has limitations with respect to converting and switching speed, full range and resolution, direct memory access (DMA), temporary storage speed and volume because common ADCs were used. Improved techniques, such as those that introduce the operational amplifier (OP-Amp), amplify the signal, reduce the connection line, and use the low pass filter (LPF) to increase the signal to noise ratio are necessary. This paper proposes the exclusive embedded ADC including OP-Amp, LPF, microprocessor and DMA circuit for the magnetic camera to satisfy the conditions mentioned above.

Robust Audio Watermarking Algorithm with Less Deteriorated Sound (음질 열화를 줄이고 공격에 강인한 오디오 워터마킹 알고리듬)

  • Kang, Myeong-Su;Cho, Sang-Jin;Chong, Ui-Pil
    • The Journal of the Acoustical Society of Korea
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    • v.28 no.7
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    • pp.653-660
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    • 2009
  • This paper proposes a robust audio watermarking algorithm for copyright protection and improvement of sound quality after embedding a watermark into an original sound. The proposed method computes the FFT (fast Fourier transform) of the original sound signal and divides the spectrum into a subbands. Then, it is necessary to calculate the energy of each subband and sort n subbands in descending order corresponding to its power. After calculating the energy we choose k subbands in sorted order and find p peaks in each selected subbands, and then embed a length m watermark around the p peaks. When the listeners hear the watermarked sound, they do not recognize any distortions. Furthermore, the proposed method is robust as much as Cox's method to MP3 compression, cropping, FFT echo attacks. In addition to this, the experimental results show that the proposed method is generally 10 dB higher than Cox's method in SNR (signal-to-noise ratio) aspect.

IGRINS Spectral Library

  • Park, Sunkyung;Lee, Jeong-Eun;Kang, Wonseok;Lee, Sang-Gak;Chun, Moo-Young;Kim, Kang-Min;Yuk, In-Soo;Lee, Jae-Joon;Mace, Gregory N.;Kim, Hwihyun;Kaplan, Kyle F.;Jaffe, Daniel T.
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.43.3-43.3
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    • 2016
  • We present a library of high-resolution (R~45,000) and high signal-to-noise ratio ($S/N{\geq}200$) near-infrared spectra of 147 standard stars. High quality spectra were obtained with Immersion GRating INfrared Spectrograph (IGRINS) covering the full range of H ($1.496-1.795{\mu}m$) and K ($2.080-2.460{\mu}m$) bands. The targets are mainly selected as MK standard stars which have well-defined spectral types and luminosity classes, and cover a wide range of effective temperatures and surface gravities. The spectra were corrected for telluric absorption lines and absolute flux calibrated using Two Micron All Sky Survey (2MASS) photometry. We find new spectral indices in H and K bands and provide their EWs. We describe empirical relations between the measured EWs and stellar atmosphere parameters such as effective temperature and surface gravity.

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A Study on Robust Design of Ball-Stop Part for Power Shift of Heavy Vehicle Using DFSS (DFSS를 이용한 상용차용 변속 배력장치의 BALL-STOP부 강건설계에 관한 연구)

  • Chung W.J.;Jung D.W.;Yoon C.H.
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.15 no.4
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    • pp.8-14
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    • 2006
  • The important function of Ball-Stop part is to operate power shift using suitable pneumatic force for vehicle with more than 5 ton when a driver changes gear. In this paper, we have applied the concept of the DFSS(Design for Six Sigma) to robust design of Ball-Stop part. First, we have found the control factors which could mainly influence the performance of the Ball-Stop part. The simulations of contact between head and detent pin was performed to evaluate effect of control factors according to DOE(Design of experiment) by using $ADAMS^{(R)}$. Finally, we have obtained optimal levels of each factors using $MINITAB^{(R)}$. Through the comparison of the result of optimized design with one of inintial design, we have verified the usefulness of DFSS method which can be applied to robust design of mechanical systems.

SPMLD: Sub-Packet based Multipath Load Distribution for Real-Time Multimedia Traffic

  • Wu, Jiyan;Yang, Jingqi;Shang, Yanlei;Cheng, Bo;Chen, Junliang
    • Journal of Communications and Networks
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    • v.16 no.5
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    • pp.548-558
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    • 2014
  • Load distribution is vital to the performance of multipath transport. The task becomes more challenging in real-time multimedia applications (RTMA), which impose stringent delay requirements. Two key issues to be addressed are: 1) How to minimize end-to-end delay and 2) how to alleviate packet reordering that incurs additional recovery time at the receiver. In this paper, we propose sub-packet based multipath load distribution (SPMLD), a new model that splits traffic at the granularity of sub-packet. Our SPMLD model aims to minimize total packet delay by effectively aggregating multiple parallel paths as a single virtual path. First, we formulate the packet splitting over multiple paths as a constrained optimization problem and derive its solution based on progressive approximation method. Second, in the solution, we analyze queuing delay by introducing D/M/1 model and obtain the expression of dynamic packet splitting ratio for each path. Third, in order to describe SPMLD's scheduling policy, we propose two distributed algorithms respectively implemented in the source and destination nodes. We evaluate the performance of SPMLD through extensive simulations in QualNet using real-time H.264 video streaming. Experimental results demonstrate that: SPMLD outperforms previous flow and packet based load distribution models in terms of video peak signal-to-noise ratio, total packet delay, end-to-end delay, and risk of packet reordering. Besides, SPMLD's extra overhead is tiny compared to the input video streaming.

SINR based Maximum Link Scheduling with Uniform Power in Wireless Sensor Networks

  • Huang, Baogui;Yu, Jiguo;Yu, Dongxiao;Ma, Chunmei
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.8 no.11
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    • pp.4050-4067
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    • 2014
  • In wireless sensor networks, link scheduling is a fundamental problem related to throughput capacity and delay. For a given set of communication requests $L=\{l_1,l_2,{\cdots},l_n\}$, the MLS (maximum link scheduling) problem aims to find the largest possible subset S of Lsuch that the links in S can be scheduled simultaneously. Most of the existing results did not consider bidirectional transmission setting, which is more realistic in wireless sensor networks. In this paper, under physical interference model SINR (signal-to-noise-plus-interference-ratio) and bidirectional transmission model, we propose a constant factor approximation algorithm MLSA (Maximum Link Scheduling Algorithm) for MLS. It is proved that in the same topology setting the capacity under unidirectional transmission model is lager than that under bidirectional transmission model. However, compared with some work under unidirectional transmission model, the capacity of MLSA is improved about 28% to 45%.

A Moving Picture Coding Method Based on Region Segmentation Using Genetic Algorithm (유전적 알고리즘을 이용한 동화상의 영역분할 부호화 방법)

  • Jung, Nam-Chae
    • Journal of the Institute of Convergence Signal Processing
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    • v.10 no.1
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    • pp.32-39
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    • 2009
  • In this paper, the method of region segmentation using genetic algorithm is proposed for an improvement of efficiency in moving picture coding. A genetic algorithm is the method that searches a large probing space using only a function value for a optimal combination consecutively. By progressing both motion presumption and region segmentation at once, we can assign the motion vector in a image to a small block or a pixel respectively, and transform the capacity of coding and a signal to noise rate into a problem of optimization. That is to say, there is close correlation between region segmentation and motion presumption in motion-compensated prediction coding. This is to optimize the capacity of coding and a S/N ratio. This is to arrange the motion vector in each block of picture according to the state of optimization. Therefore, we examined both the data type of genetic algorithm and the method of data processing to obtain the results of optimal region segmentation in this paper. And we confirmed the validity of a proposed method using the test pictures by means of computer simulation.

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Determination of Total Phenols in Environmental Waters by Capillary-HPLC with U.S.E.P.A. Classified Eleven Priority Pollutant Phenols after Nitrosation and Their Visible Spectrophotometric Detection

  • Chung, Yong-Soon
    • Bulletin of the Korean Chemical Society
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    • v.26 no.2
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    • pp.297-302
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    • 2005
  • The determination of total phenols was accomplished by capillary-high performance liquid chromatography (capillary-HPLC) after nitrosation of the U.S.E.P.A. classified 11 priority pollutant phenols, using the nitrosated parent phenol (POHNO) as a reference for calibration. The optimum mobile phase composition for this analysis was found by examining the effect of changing the percentage of acetonitrile (MeCN) in the mobile phase on retention factors (k values) and peak intensities. As MeCN percentage was increased, k values were reduced and peak intensities were generally increased. From the results obtained, it was found that the optimum mobile phase was 90%(v/v) MeCN solution at pH 8.0, the detection wavelength of 400 nm, and a detection limit (D.L., concentration at signal to noise ratio (S/N) of 3.0) of 4.5 ${\times}$ $10^{-7}$ M. In addition, 10 of the 11 phenols present in mineral or waste water were separated after the nitrosation by capillary-HPLC. The optimum mobile phase for separation was a 40%(v/v) MeCN solution at pH 5.0.

A New Measurement Method of the Ground Resistance Using a Low-pass Filter in Energized Substations (지역필터를 이용한 수변전실 접지저항의 새로운 측정방법)

  • Lee, Bok-Hui;Eom, Ju-Hong;Lee, Seung-Chil;Kim, Seong-Won;An, Chang-Hwan
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.50 no.8
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    • pp.387-393
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    • 2001
  • This paper describes an advanced measuring method and precise evaluation of the ground resistance for the grounding system of energized substations and power equipments. A grounding system of substations consists of all interconnected grounding connections of grounded conductors, neutral ground wires, underground conductors of distribution lines, cable shields, grounding terminals of equipments, and etc. It is very difficult to measure the accurate ground resistance of the grounding terminals of equipments, and etc. It is very difficult to measure the accurate ground resistance of the grounding system of high voltage energized substations because of harmonic components caused by switched power supplies or overloads. The conventional fall-of-potential method may be subject to big error if stray ground currents and potentials are present. In this work, to improve the precision in measurements of the ground resistance by eliminating the effects of harmonic components and stray currents and potentials, the investigations of the ground resistance measurement by using a low pass filter in a model energized grounding system were conducted. The accuracy of ground resistance mesurements was evaluated as a function of the ratio of the test signal to noise (S/N). The errors due to the proposed ground resistance measurement method were decreased with increasing S/N and were less than 5[%] as S/N is 10. The proposed ground resistance measurement method appears to be considerably more accurate than the conventional fall-of -potential method. It is allows cancellation of the parasitic resistance of energized grounding systems, to employ the measurement method that allows cancellation of the parasitic effects due to other circulating ground currents and ground potential rises in practical situations.

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