• 벤처창업연구
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• 제12권5호
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• pp.127-139
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• 2017

본 논문은 '의도(Intention)는 행동을 예측할 수 있다'는 사회 심리학자들의 연구에 근간을 두고 사회적 기업가적 의도(Social Entrepreneurial Intention)에 영향을 미치는 요소들이 무엇인지를 규명하고자 하였다. Ajzen의 계획된 행동이론(Theory of Planned Behavior: TPB)과 Shapero의 기업가정신행동모델(Shapero's Model of the Entrepreneurial Event: SEE)에 근간하여 많은 연구들은 기업가적 의도(Entrepreneurial Intention)에 영향을 미치는 요소로 자기 효능감(Self Eficacy), 지각된 욕구(Perceived Desirability), 지각된 실현가능성(Perceived Feasibility) 등이 있음을 규명하였다. 이러한 연구에 기반하여 본 연구는 사회적 기업가정신 맥락에서 사회적 공감(Compassion), 도덕적 의무감(Moral Obligation), 사회적 지지에 대한 인식(Perceived Social Support)이 사회적 기업가적 의도에 영향을 미치는 요소임을 밝히고자 하였다. 공감(Compassion)은 다른 사람이 느끼는 감정이 무엇인지를 이해하는 능력으로 일반인 혹은 일반 기업인들에 비해 사회적 기업가가 갖는 두드러진 특성이다. 또한 사회적 기업가는 사회적 기업가적 활동을 하는데 있어서 도덕적 의무감을 주관적 규범으로서 중시한다. 또한 개인이 갖는 특성 변수 외에 외생적 요소로 사회적 지지에 대한 인식을 어떻게 하느냐가 사회적 기업가적 의도에 중요한 영향을 미친다. 본 연구는 자발적으로 사회적 기업가정신 및 기업가정신 과목 수강을 선택한 대학생 271명을 대상으로 하였으며 회귀분석을 통해 가설검증을 하였다. 공감능력(인지적 공감, 정서적 공감, 사회문제 공감)과 주관적 규범으로의 도덕적 의무감은 사회적 기업가적 의도에 영향을 미치며, 외부 환경에 대한 인식 즉 사회적 지지에 대한 인식의 정도에 따라 사회적 기업가적 의도는 영향을 받는 것으로 나타났다. 기존의 사회적 기업가정신에 영향을 미치는 요소들을 규명하는 연구들이 주로 기존 기업가정신 연구에서 사용된 변수를 사용함으로써 사회적 기업가정신의 특성을 잘 설명하지 못한다는 한계를 가지고 있었다. 본 연구는 공감, 도덕적 의무감, 사회적 지지에 대한 인식이 의도(Intention)에 영향요소임을 밝힘으로써 사회적 기업가적 의도 연구 분야에 기여했다고 볼 수 있다. 그러나 사회적 기업가적 의도를 파악하는데 있어서 학생들만을 대상으로 한 것은 본 연구의 한계점이라고 할 수 있다.

• 생태와환경
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• 제37권4호통권109호
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• pp.411-422
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• 2004

횡성호에서는 수중폭기 기간에도 수온약층이 형성되었으며, 수중폭기로 인한 영향이 크지 않은 것으로 판단된다. 모든 정점의 표충(0-5m)평균 탁도는 0.1-8.5NTU로 우기 이후에 중층 및 심층에서 높았다. 투명도는 0.9-3.5m의 범위로 댐 하류(St. 1)정점에서 크게 나타났으며, 상류로 갈수록 낮았다. 용존산소는 2000년 7월과 8월에 전 지점의 0m에서 $8.4-14.1\;mgO_2\;{\cdot}\;L^{-1}$로 높았으나 심층에서는 고갈 상태를 보였다. 또한 2001년 7월과 9월에도 정점 1의 심층에서 $1\;mgO_2\;{\cdot}\;L^{-1}$ 내외로 매우 낮았다. 전 정점의 표층 (0-5 m)평균 총인 농도는 5-46 mgP ${\cdot}$ $m^{-3}$로 초봄의 turnover 직후 및 우기이후에 높았으며 용존 무기인 농도는 0.2-13.2 mgP ${\cdot}$ $m^{-3}$로 2001년 9월을 제외하고는 대부분10mgp ${\cdot}$ $m^3$이하 이였다. 횡성호의 연간 인부하량은 약 4.45ton 정도로 유역내에서 발생되는 총인 발생량 71.34ton중 약 6.2%만이 호수내로 유입되는 것으로 나타났다. 수면적당 인부하량은0.77 gp ${\cdot}\;m^2\;{\cdot}\;yr^{-1}$으로 횡성호의 환경용량이라 할 수 있는 과잉임계부하량 0.72 gp ${\cdot}\;m^2\;.\;yr^{-1}$을 0.05 gP ${\cdot}\;m^2\;.\;yr^{-1}$ 초과한 수준이다. 전 정점 표층 (0-5 m)평균 총질소 농도는 0.83-3.55 mgN ${\cdot}\;L^{-1}$로 우기 이후에 중충 이하 지역에서 높았다. 질산성 질소는 전 정점의 표층(0-5m)평균이 0.09-3.33 mgN ${\cdot}\;L^{-1}$로 2001년 6월에 가장 낮았다. 암모니아성 질소는 전 정점의 표층(0-5m)평균이 0.04-0.23 mgN ${\cdot}\;L^{-1}$이였다. 전 정점 표층 (0-5 m)평균 규소농도는 0.5-9.6 mgSi ${\cdot}\;L^{-1}$로 봄철에 낮았으며, 우기이후에 다시 증가하였다. 평균 TSI는 2000년과 2001년에 각각 59와 57이었다. 전 정점 표층 (0-5 m)평균 엽록소 a농도는 0.3-32.4 mg ${\cdot}\;m^{-3}$로 여름철에 높은 경향을 보였으며, 정점별로는 상류지역에서 높았다. 식물플랑크톤은 2000년 7월에 녹조류인 Scenedesmus sp.가 10,480 cells ${\cdot}\;mL^{-1}$,8월과 9월에는 남조류인 Microcystis sp.가 각각 3,492와 296 cells ${\cdot}\;mL^{-1}$로 우점하였다. 10월에는 녹조류인 Coelastrum microporum이 133 cells ${\cdot}\;mL^{-1}$, 11월에는 규조류인 Asterionella formosa가 2,654 cells ${\cdot}\;mL^{-1}$, 12월에는 규조류인 .Aulacoseira granulata가 29 cells ${\cdot}\;mL^{-1}$우점종이였다. 특히 2000년 여름철에 우점종이였던 남조류가 2001년에는 출현하지 않았으며 종 다양성 (diversity)지수는 2000년 7월에 2.22로 가장 높았으며, 생물량도 조사기간중 36,640 cells ${\cdot}\;mL^{-1}$로 가장 많았다.

• 항공우주정책ㆍ법학회지
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• 제4권
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• pp.7-35
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• 1992

The expansion of air transport on a global scale with ever increasing traffic densities has brought about problems that must be solved through new multilateral mechanisms. Looking to the immediate future, air transport will require new forms of international cooperation in technical and economic areas. Air transport by its very nature should have been a counterforce to nationalism. Yet, the regulatory system in civil aviation is still as firmly rooted in the principle of national sovereignty as when it was first proclaimed at t-11e Paris Convention of 1919 and reaffirmed in the Chicago Convention. Sovereignty over the airspace has remained the cornerstone of relations between states in all respects of air transport. The importance of sovereignty over air space embodied in article 1 of the Chicago Conrenton also is responsible for restricting the authority of ICAO as an intergovernmental regulatory agency. The Orgenization, for all its extensive efforts, has only limited authority. ICAO sets standards but cannot enforce them; it devises solutions but cannot impose them. To implement its rules ICAO most rely not so much on legal requirements as on the goodwill of states. It has been forty-eight years since international community set the foundations of the international system in civil aviation action. Profound political, economic and technological changes have taken place in air transport. The Chicago Convention is living proof that staes can work together to make air transport a safe mode of travel. The law governing international civil auiation is principally based on international treaties and on other regulation agreed to by governments, for the most part through the mechanism of ICAO. The role of ICAO international standards and recommended practices and procedures dealing with a broad range of technical matters could hardly be overestimated. The organization's ability to develop these standards and procedures, to adapt them continuously to the rapid sate of change and development of air transport, should be particularly stressed. The role of ICAO in the area of the development of multilateral conventions on international air law has been successful but to a certain degree. From the modest starting-point of the Tokyo Convention, we have seen more adequate international instruments prepared within the scope of ICAO activities, adopted: the Hague Convention of 1970 for the suppression of Unlawful Seizure of Aircraft and the Montreal Convention of 1971 for the Suppression of Unlawful Acts against the Safety of Civil Aviation. The work of ICAO in the new domain of international law conventions concerning what has been loosely termed above as the criminal problems connected with international air transport, in particular the problem of armed aggression against aircraft, should be positively appreciated. But ICAO records in the domain of developing a uniform legal system of international carriage by air are rather disappointing. The problem of maintaining and developing the uniformity of this regulation exceeds the scope of interest and competence of governmental transport agencies. The expectations of mankind linked to it are too great to give up trying to restore the uniform legal system of international air carriage that would create proper conditions for its further growth. It appears that ICAO has, at present, a good opportunity for doing this. The hasty preparation of ICAO draft conventions should be definitely excluded. Every Preliminary draft convention ought to be sent to Governments of all member-States for consideration, So that they could in form ICAO in due time of their observation. The problom of harmonizing a uniform law of international air carriage with that of other branches of international transport should demand more and more of its attention. ICAO cooperation with other international arganization, especially these working in the field of international transport, should be strengthened. ICAO is supposed to act as a link and a mediator among, at times the conflicting interests of member States, serving the happiness and peace of all of the world. The transformation of the contemporary world of developing international relations, stimulated by steadily growing international cooperation in its various dimensions, political, economic, scientific, technological, social and cultural, continuously confronts ICAO with new task.

• 한국간호교육학회지
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• 제3권
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• pp.78-98
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• 1997

Health education, as the most fundamental concept for national health promotion, alms for developing the self-care ability of the general public. High school days are regarded as the period when most important physical, mental and social developments occur, and most health-related behaviors are formed. School health education is one of the major learning resources influencing health potential in the home and community as well as for the individual student. High school health education in Korea has a fundamental systemic flaw in that health-related subjects are divided and taught under various subjects areas at school. In order to achieve the goal of school health education, it is essential to make a systematic assessment of the learner's concerns connected with his health and life, and the factors affecting them. So far, most of the research projects that had been carried out for improving high school health education were limited in their concerns to a particular aspect of health. Even though some had been done in view of comprehensive school health education, they failed to Include a health assessment of the learner. Therefore, in this study the high school students' concerns related to health and life were investigated in the first place on the basis of the PRECEDE model, developed by Green and others for the purpose of a comprehensive diagnostic research on high school health education. This study was done in two steps : one was the basic study for developing research instrument and the other was the main one. The former was conducted at five high schools in Seoul and Cheongju for 2 months-beginning in March, 1996. The students were asked to respond to questions related to their health and lives in unstructured open-ended question forms. On the basis of analysis of the basic study, the diagnostic instruments for the quality of life, health problems, health behavior and educational factors were constructed to be used for the collection of data for main study. An expert panel and the pilot study were used to improve content validity and reliability of the instruments. The reliability of the instruments was measured at between .7697 and .9611 by the Cronbach $\alpha$. The data for this study were collected from the sample consisted of the junior and senior classes of twenty general and vocational high schools in Seoul and Cheongju for two months period beginning in July, 1996. In analyzing the data, both t-test and $X^2$-test were done by using SAS-$PC^+$ Program to compare data between the sexes of the high school students and the types of high school. A canonical correlation analysis was carried out to determine the relationships among the diagnostic variables, and a multivariate multiple regression analysis was conducted by using LISREL 8.03 to ascertain the influences of variables on the high school students' health and quality of life. The results were as follows : 1) The findings of the hypothesis tests (1) The canonical correlation between the educational diagnosis variables and behavioral, epidemiological, social diagnosis variables was .7221, which was significant at the level of p<.001. (2) The canonical correlation between the educational diagnosis variables and the behavior variables was .6851, which also was significant (p<.001). (3) The canonical correlation between the behavioral diagnosis variables and the epidemiological variables was 4295, which was significant (p<.001). (4) The canonical correlation between the epidemiological diagnosis variables and the social variables was .6005, which was also significant (p<.001). Therefore, the relationship between each diagnosis variable suggested by the PRECEDE model had been experimentally proven to be valid, supporting the conceptual framework of the study as appropriate for assessing the multi-dimensional factors affecting high school students' health and quality of life. Health behavior self-efficacy, the level of parents' interest and knowledge of health, and the level of the perception of school health education, all of which are the educational diagnostic variables, are the most influential variables in students' health and quality of life. In particular, health behavior self-efficacy, a causative factor, was one of the main influential variables in their health and quality of life. Other diagnostic variables suggested in the steps of the PRECEDE model were found to have reciprocal relations rather than a unidirectional causative relationship. The significance of this research is that it has diagnosed the needs of high school health education by the learner-centered assessment of variety of factors related to the health and the life of the students. This research findings suggest an integrated system of school health education to be contrived to enhance the effectiveness of the education by strengthening the influential factors such as self-efficacy to improve the health and quality of the lives of high school students.

• Journal of Plant Biotechnology
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• 제33권3호
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• pp.195-207
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• 2006

Stem cells are the primordial, initial cells which usually divide asymmetrically giving rise to on the one hand self-renewals and on the other hand progenitor cells with potential for differentiation. Zygote (fertilized egg), with totipotency, deserves the top-ranking stem cell - he totipotent stem cell (TSC). Both the ICM (inner cell mass) taken from the 6 days-old human blastocyst and ESC (embryonic stem cell) derived from the in vitro cultured ICM have slightly less potency for differentiation than the zygote, and are termed pluripotent stem cells. Stem cells in the tissues and organs of fetus, infant, and adult have highly reduced potency and committed to produce only progenitor cells for particular tissues. These tissue-specific stem cells are called multipotent stem cells. These tissue-specific/committed multipotent stem cells, when placed in altered environment other than their original niche, can yield cells characteristic of the altered environment. These findings are certainly of potential interest from the clinical, therapeutic perspective. The controversial terminology 'somatic stem cell plasticity' coined by the stem cell community seems to have been proved true. Followings are some of the recent knowledges related to the stem cell. Just as the tissues of our body have their own multipotent stem cells, cancerous tumor has undifferentiated cells known as cancer stem cell (CSC). Each time CSC cleaves, it makes two daughter cells with different fate. One is endowed with immortality, the remarkable ability to divide indefinitely, while the other progeny cell divides occasionally but lives forever. In the cancer tumor, CSC is minority being as few as 3-5% of the tumor mass but it is the culprit behind the tumor-malignancy, metastasis, and recurrence of cancer. CSC is like a master print. As long as the original exists, copies can be made and the disease can persist. If the CSC is destroyed, cancer tumor can't grow. In the decades-long cancer therapy, efforts were focused on the reducing of the bulk of cancerous growth. How cancer therapy is changing to destroy the origin of tumor, the CSC. The next generation of treatments should be to recognize and target the root cause of cancerous growth, the CSC, rather than the reducing of the bulk of tumor, Now the strategy is to find a way to identify and isolate the stem cells. The surfaces of normal as well as the cancer stem cells are studded with proteins. In leukaemia stem cell, for example, protein CD 34 is identified. In the new treatment of cancer disease it is needed to look for protein unique to the CSC. Blocking the stem cell's source of nutrients might be another effective strategy. The mystery of sternness of stem cells has begun to be deciphered. ESC can replicate indefinitely and yet retains the potential to turn into any kind of differentiated cells. Polycomb group protein such as Suz 12 repress most of the regulatory genes which, activated, are turned to be developmental genes. These protein molecules keep the ESC in an undifferentiated state. Many of the regulator genes silenced by polycomb proteins are also occupied by such ESC transcription factors as Oct 4, Sox 2, and Nanog. Both polycomb and transcription factor proteins seem to cooperate to keep the ESC in an undifferentiated state, pluripotent, and self-renewable. A normal prion protein (PrP) is found throughout the body from blood to the brain. Prion diseases such as mad cow disease (bovine spongiform encephalopathy) are caused when a normal prion protein misfolds to give rise to PrP$^{SC}$ and assault brain tissue. Why has human body kept such a deadly and enigmatic protein? Although our body has preserved the prion protein, prion diseases are of rare occurrence. Deadly prion diseases have been intensively studied, but normal prion problems are not. Very few facts on the benefit of prion proteins have been known so far. It was found that PrP was hugely expressed on the stem cell surface of bone marrow and on the cells of neural progenitor, PrP seems to have some function in cell maturation and facilitate the division of stem cells and their self-renewal. PrP also might help guide the decision of neural progenitor cell to become a neuron.

• Journal of Preventive Medicine and Public Health
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• 제30권3호
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• pp.630-642
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• 1997

60세이상 노인인구를 대상으로 '농촌지역 노인들의 우울 및 인지기능 장애에 관한 연구'를 한 이정애와 정향균의 연구대상 558명에 대해 농촌지역 노인들의 인지기능 장애와 사망과의 관련성을 살펴본 결과는 다음과 같다. 1) 3년동안 동안 전체 대상자의 사망률은 558명중 57명인 10.2%이었으며 353명의 정상 인지기능군 중 사망자는 30명으로 사망률 8.5%, 126명 의 경도 인지장애군중 사망자는 14명으로 사망률 11.1%, 79명의 중증 인지장애군중 사망자는 13명으로 사망률 16.5% 이었다(표 3). 2) 3년동안 전체 연구 대상자의 생존율은 0.91이었으며 정상, 경도, 중증 인지기능 장애군의 3년 생존율은 각각 0.92, 0.90, 0.86이었다. 로그 순위 검정법으로 인지기능 정상군과 경도 및 중증의 각 인지기능 장애군의 생존곡선을 비교한 결과 통계적으로 유의하지 않았다. 또한 인지기능 정상군과 경도 이상의 인지기능 장애군간 생존곡선을 비교한 결과도 유의한 차이는 없었다. 3) 혼란변인을 보정하지 않는 Cox의 비례위험 회귀 모형의 단변량분석의 결과 95% 신뢰구간(C.I. : Confidence Interval)에서 사망위험도가 유의한 변인은 연령, 월수입, 흡연습관, 신체장애 등이었으며, 인지기능 장애정도를 정상 그리고 경도 및 중증으로 분류한 분석에서는 정상군에 비해 경도 및 중증의 사망위험도가 유의하게 높지 않았으나, 인지기능 점수(MMSEK score)의 증가에 따른 분석 결과 사망위험도가 0.94로 유의하게 낮게 나타났다(표 4). 4) 잠재적 혼란변인들의 영향을 보정한 Cox의 비례위험 회귀모형의 다변량 분석의 결과 인지기능 장애정도 및 MMSEK 점수증가에 따른 사망위험도는 어느 모형에서도 인지기능 장애정도가 사망에 미치는 위험도는 통계적으로 유의하지 않았다(표 5). 5) 남녀별로 각각 인지기능 장애와 사망위험도와의 관계를 알아보기 위해 다변량 분석을 시행한 결과 인지기능 장애정도 및 MMSEK 점수 증가에 따른 사망위험도는 어느 모형에서도 인지기능 장애정도가 사망에 미치는 위험도는 통계적으로 유의하지 않았다(표 6, 표 7). 이상 본 연구는 농촌지역 노인들에서 인지기능 장애정도가 사망에 미치는 영향을 알아보고자 하였지만, 인지기능 장애정도가 사망에 미치는 영향을 통계적으로 유의하게 고찰하지 못하였다.