• Journal of Intelligence and Information Systems
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• v.28 no.3
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• pp.209-235
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• 2022

Starting from 2010, blockchain technology, along with the development of artificial intelligence, has been in the spotlight as the latest technology to lead the 4th industrial revolution. Furthermore, previous research regarding blockchain's technological applications has been ongoing ever since. However, few studies have been examined the standards for classifying the blockchain economic ecosystem from a capital market perspective. Our study is classified into a collection of interviews of software developers, entrepreneurs, market participants and experts who use blockchain technology to utilize the blockchain economic ecosystem from a capital market perspective for investing in stocks, and case study methodologies of blockchain economic ecosystem according to application fields of blockchain technology. Additionally, as a way that can be used in connection with equity investment in the capital market, the blockchain economic ecosystem classification methodology was established to form an investment universe consisting of global blue-chip stocks. It also helped construct an intelligent portfolio through quantitative and qualitative analysis that are based on quant and artificial intelligence strategies and evaluate its performances. Lastly, it presented a successful investment strategy according to the growth of blockchain economic ecosystem. This study not only classifies and analyzes blockchain standardization as a blockchain economic ecosystem from a capital market, rather than a technical, point of view, but also constructs a portfolio that targets global blue-chip stocks while also developing strategies to achieve superior performances. This study provides insights that are fused with global equity investment from the perspectives of investment theory and the economy. Therefore, it has practical implications that can contribute to the development of capital markets.

• Journal of People, Plants, and Environment
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• v.23 no.5
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• pp.521-535
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• 2020

Background and objective: This study investigated plant type and color preference and conducted a psychological assessment for gardening activities of firefighters in a high-risk occupational group. Methods: A survey was conducted on 117 firefighters aged 39.01±9.17 in Sunchang in March 2020 to examine their preferences in plant type and color and conduct a psychological assessment of firefighters on gardening activities. Results: For plant experience and awareness, plant-related event showed the highest score, followed by plant preference tendency and plant growing experience. The level of plant gardening activities was higher among older age and higher job position. As a result of examining the quality of life according to the demographic characteristic with WHOQOL-BREF (World Health Organization Quality of Life Assessment Instrument), it was found that the quality of life was higher among the 20s-30s than 50s, firefighter position than fire lieutenant or higher, those with higher average monthly income, and the singles group than married (p < .05). The administration group showed lower scores than the fire suppression group working in the field, showing statistical significance. Most firefighters showed high preference for herbal plants among the 12 types of flowering plants, in the order of Rosmarinus officinalis>Lavandula spp.>Mentha piperita, Calendula officinalis. Pelargonium spp. was preferred the least out of the flowering plants, Lycopersicon esculentum was preferred the most out of 12 types of vegetable plants, while Angelica acutiloba was preferred the least statistical significance. For the preference of plant colors, yellow was the most preferred color, followed by white, blue, orange, red, and green, showing statistical significance. For the psychological survey responses of emotion words toward 6 plants colors, it was found that 'bright' was the emotion felt most strongly by the white, yellow, and orange groups, 'calm' and 'comfortable' by the green and blue groups, and 'fancy' by the red group. Conclusion: The effect of agro-healing programs can be increased by using mostly yellow plants when creating indoor healing gardens at the workplaces of fire officials in a high-risk occupational group, and using herbal plants and Lycopersicon esculentum in the gardens for agro-healing activities.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.50 no.12
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• pp.899-907
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• 2022

According to the Unmanned aircraft system Traffic Management (UTM), drones are permitted to fly up to 150m above ground, which is located in the atmospheric boundary layer where there is considerable wind fluctuation due to turbulence. Although it is difficult to predict when turbulence will occur drone aviation safety could be enhanced by having a better understanding of the characteristics of vertical profile of wind in the flight area. We used wind lidar (WIndMast 350M) to observe vertical profiles of wind at the test site for aviation meteorological observation equipment located near Incheon International Airport in July and September, 2022. In this study, we utilized the observed wind profile data to propose a technique for obtaining information that could help improve the drone aviation safety. The Fourier transform analysis is used to evaluate the temporal characteristics of the horizontal wind speed at various vertical levels up to 350m. We also examined the relative contribution of the variance of wind having scales of less than an hour, a crucial scale for drone flight, to the variance of wind having all scales at each vertical altitude for days with and without precipitation.

• Journal of Life Science
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• v.32 no.8
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• pp.641-646
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• 2022

There are concerns about the environmental release of living modified organism (LMO) maize created to increase yields. In fact, there are cases in which LMO crops for feed have been leaked in Korea to form autoite colonies, and concerns about LMO spill are intensifying. In this study, the possibility of environmental outflow and occurrence of native organisms was analyzed using maize feed and seeds distributed in Korea. In the evaluation of the possibility of spontaneous occurrence of maize in the event of an unintentional release of maize feed made by crushing maize, the incidence rate of maize was 0.01%, which was extremely low compared to the germination rate of maize seeds. A survey of the dormant rate of maize showed that all maize seeds collected every month were dead. In the germination rate test by temperature using Daehak wax corn and Kwangpyeongok, high germination rates were found at 20℃ and 30℃, and relatively low germination rates were found at 10℃ and 40℃. In addition, all germination tests showed a higher germination rate Daehak wax corn than Kwangpyeongok. The difference between domestic and overseas cultivation maize was confirmed through a survey on the agricultural properties of three varieties of maize. The data obtained through this experiment could be the basis for the evaluation of the weediness potential of environmental risk assessment and technology to suppress the occurrence of autoite in preparation for future LMO spills.

• Journal of the Korean Society for Library and Information Science
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• v.57 no.1
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• pp.23-44
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• 2023

The word library(図書館) is a Japanese translation of the Western library or Bibliothek in the mid-Meiji period. This word has been accepted in Chinese(图书馆), Taiwan(圖書館), Korea(도서관), and Vietnam(Dđồ thư quán), which are Chinese-speaking countries. If so, when and who first introduced the term library to Japan and China? In Japan, the enlightenment thinker Fukuzawa's 『Seiyo Jijo, 1866』 is regarded as the first document to introduce the Western library, and in China, the article published in 『Qing Yi Bao, 1896』 by the reformed thinker Liang Qichao referred to as the first example. Therefore, this study traced and demonstrated the time and person in which the word library appeared, focusing on modern dictionaries, books, translations, papers, and newspaper articles that were introduced in both countries. As a result, the theory of the introduction to Fukuzawa in 1866 is wrong because Western libraries are described in various terms in many diaries and dictionaries, including Motoki's 『An English Japanese Dictionary of the Spoken Language, 1814』. Also, in China, the theory of introduction of Liang Qichao in 1896 is not true because the term library first appeared in Ryu Jeong-dam's 『A Dictionary of Loan Words and Hybrid Words in Chinese, 1884』. In the same context, it is necessary to trace and argue the history of the first use of the term library in Korea and the name of the first library in Korea established by the Busan Branch of the Japan Hongdo Association in 1901.

• BMB Reports
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• v.55 no.12
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• pp.609-614
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• 2022

Mutation of the gene for adenomatous polyposis coli (APC), as seen in Apc^Min/+ mice, leads to intestinal adenomas and carcinomas via stabilization of β-catenin. Transmembrane 4 L six family member 5 (TM4SF5) is involved in the development of non-alcoholic fatty liver disease, fibrosis, and cancer. However, the functional linkage between TM4SF5 and APC or β-catenin has not been investigated for pathological outcomes. After interbreeding Apc^Min/+ with TM4SF5-overexpressing transgenic (Tg^TM4SF5) mice, we explored pathological outcomes in the intestines and livers of the offspring. The intestines of 26-week-old dual-transgenic mice (Apc^Min/+:Tg^TM4SF5) had intramucosal adenocarcinomas beyond the single-crypt adenomas in Apc^Min/+ mice. Additional TM4SF5 overexpression increased the stabilization of β-catenin via reduced glycogen synthase kinase 3β (GSK3β) phosphorylation on Ser9. Additionally, the livers of the dualtransgenic mice showed distinct sinusoidal dilatation and features of hepatic portal hypertension associated with fibrosis, more than did the relatively normal livers in Apc^Min/+ mice. Interestingly, TM4SF5 overexpression in the liver was positively linked to increased GSK3β phosphorylation (opposite to that seen in the colon), β-catenin level, and extracellular matrix (ECM) protein expression, indicating fibrotic phenotypes. Consistent with these results, 78-week-old Tg^TM4SF5 mice similarly had sinusoidal dilatation, immune cell infiltration, and fibrosis. Altogether, systemic overexpression of TM4SF5 aggravates pathological abnormalities in both the colon and the liver.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.6
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• pp.209-212
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• 2022

We recently reported that Gastrodia elata extracts (GEE) had an effects to protect against lipopolysaccharide-induced cognitive impairment in vivo model. In this study, we investigated the neuroprotective effects and the mechanism of action of GEE in hydrogen peroxide (H₂O₂)-induced cell death of SH-SY5Y human neuroblastoma cell. The SH-SY5Y cells were divided into five groups, including control(non-treated group), 100 μM H₂O₂, 100, 200, 500 ㎍/㎖ GEE+ 100 μM H₂O₂ groups. Pre- and co-treatment with GEE prevented cell death induced by 100 μM H₂O₂ for 24 h in SH-SY5Y cells. Our findings also showed that anti-oxidants enzymes (Cu/Zn superoxide dismutase, Mn superoxide dismutase, catalase) were up-regulated by 100 μM H₂O₂. But GEE suppressed H₂O₂-induced anti-oxidants enzymes decrease in a dose-dependent manner. Treatment with GEE also inhibited phosphorylation of eukaryotic initiation factor-2α (eIF-2α) and p38 by H₂O₂. Taken together, the neuroprotective effects of GEE in terms of recovery of antioxidant enzymes expression, down-regulation of eIF-2α and p38 phosphorylation, and inhibition of cell death are associated with reduced oxidative stress in SH-SY5Y cells.

• Microbiology and Biotechnology Letters
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• v.50 no.4
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• pp.533-547
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• 2022

This study investigated the hair growth effect of Schisandra chinensis extract (TS-SC) and TS-SC fermented by Lactobacillus plantarum (TS-SCLF) on human dermal papilla cells (hDPCs). The production of vascular endothelial growth factor (VEGF), insulin-like growth factor 1 (IGF-1), keratinocyte growth factor/fibroblast growth factor 7 (KGF/FGF-7) and hepatocyte growth factor (HGF), transforming growth factor beta 1 (TGF-β1) were examined. The secretion rates of VEGF and KGF/FGF-7 were high in TS-SC, and the secretion rates of IGF-1 and HGF were high in TS-SCLF. TGF-β1 was inhibited in a concentration-dependent manner in all samples. Gene expression of VEGF, IGF-1, KGF, HGF and alkaline phosphatase, relevant to hair growth, were examined. The data revealed that TS-SC and TS-SCLF successfully promoted hair growth in hDPCs. The IGF-1 gene was expressed in a dose-dependent manner in TS-SCLF. These results indicate that TS-SC and TS-SCLF fermented extract effectively promoted hair growth and gene expression relevant to hair growth in hDPCs. Used in clinical trials the test substance 'CMK-LPF01' showed a statistically significant increase in the number of hairs at 8 weeks, 16 weeks, and 24 weeks compared to before product use, and a change in hair growth, a secondary efficacy evaluation variable. Through additional research in the future, it is expected that "CMK-LPF01" can be developed as a functional material that can help alleviate symptoms of hair loss.

• Journal of Korean Tunnelling and Underground Space Association
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• v.25 no.3
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• pp.201-220
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• 2023

Power cable tunnels is one of the underground structures meant for electricity transmission and are constructed using shield TBM method when transitting across urban and subsea regions. With the increasing shaft depth for tunnels excavation when the shield TBM excavated the rock mass, the review of selecting closed-type shield TBM in rocks becomes necessary. A simplified shield TBM design method is also necessary based on conventional geotechnical survey results. In this respect, design method and related design program are developed based on combined results of full-scale tests, considerable amount of accumulated TBM data, and numerical simulation results. In order to validate the program results, excavation data of a completed power cable tunnel project are utilized. Thrust force, torque, and power of shield TBM specification are validated using Kernel density concept which estimates the population data. The robustness of design expertise is established through this research which will help in stable provision of electricity supply.

• Journal of Korean Tunnelling and Underground Space Association
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• v.25 no.5
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• pp.357-371
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• 2023

In cable tunnel construction using TBM, the vertical shaft is an essential structure for entrance and exit of TBM equipment and power lines. Since a shaft penetrates the ground vertically, it often encounters rock mass. Blasting or rock splitting methods, which are mainly used to the rock excavation, cause public complaints due to the noise, vibration and road occupation. Therefore, mechanical excavation using vertical shaft excavation machine are considered as an alternative to the conventional methods. However, at the current level of technology, the vertical excavation machine has limitation in its performance when applied for high strength rock with a compressive strength of more than 120 MPa. In this study, the potential utilization of waterjet technology as an excavation assistance method was investigated to improve mechanical excavation performance in the hard rock formations. Rock cutting experiments were conducted to verify the cutting performance of the abrasive waterjet. Based on the experimental result, it was found that ensuring excavation performance with respect to changing in ground conditions can be achieved by adjusting waterjet parameters such as standoff distance, traverse speed and water pressure. In addition, based on the relationship between excavation performance, uniaxial compressive strength and RQD, it was suggested that excavation performance could be improved by artificially creating joints using the abrasive waterjet. It is expected that these research results can be utilized as fundamental data for the introduction of vertical shaft excavation machines in the future.