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Optimization of the whole extract of Zarawand Mudaharaj (Aristolochia rotunda L.) root by Response Surface Methodology (RSM)

  • Ansari, MD Zakir;Sofi, Ghulamuddin;Hamiduddin, Hamiduddin;Ahmad, Haqeeq;Basri, Rabia;Alam, Abrar
    • CELLMED
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    • v.11 no.3
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    • pp.15.1-15.9
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    • 2021
  • The chemical constitution of a drug has been accepted as an important basis for pharmacological action in Unani medicine. Various dosage forms have been developed on this concept, such as decoctions (Joshanda), infusions (Khesanda), extract (Rub / Usara), and syrup. Zarawand Mudaharaj (ZM.) / Aristolochia rotunda L. root was subjected to extraction process using Soxhlet's apparatus by using Response Surface Methodology (RSM) to design the number of random runs of the extracts with variation in the factors of temperature, the concentration of ethanol in water, time for extraction, for optimizing and maximizing the yield concentration. The data obtained, was analyzed with regression equation and ANOVA two-way summary to interpret the interaction of the factors for yield maximization. Minitab version 18 was used to design and analyze data. Validation of the optimum conditions for maximum yield of the whole extract of ZM. Root was carried out by re-run of the extract using the optimized conditions. The maximum yield percentage thus obtained using RSM was 20.87% whereas using these optimum conditions 21.35 % yield was obtained thereby validating the method. The association between the response functions and the process variables was identified by a three-factor recorded Box-Behnken design. In the present study RSM is used because itis a cheap and affordable method to optimize maximum yield percentage which may be reliably used by researchers. The study set in the surface conditions for ZM. root extraction by the Soxhlet apparatus for maximizing the yield percentage.

Factors of Stress and Rehabilitation Motivation among Orthopedic Hospital Inpatients at a Military Hospital (군병원 정형외과 입원환자의 스트레스 및 재활동기 영향 요인)

  • Kim, Ha Na;Kim, Seung Won
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.32 no.2
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    • pp.195-207
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    • 2022
  • Objectives: The purpose of this study was to identify the factors affecting rehabilitation motivation in hospitalized orthopedic patients. Methods: Data were collected from June 1th to July 31th, 2019 and structured questionnaires were used. Study subjects were 97 orthopedic patients who received fixed treatment more than two weeks and started rehabilitation exercise in a military hospital. The data were summarized using descriptive statistics and analyzed by t-test or one way ANOVA, Pearson's correlation analysis and multiple regression analysis were run in SPSS 20.0 program. Results: The results of this study may be summarized as follows. (1) The demographic characteristics that showed differences in rehabilitation motivation were marital status, age and the ranks of the armed forces. The rehabilitation motivation of married, older than 31, officer ranked soldiers turned out to be higher than those of singles, younger than 30, non-officers, respectively. (2) The results of Pearson's correlation analysis showed that independent variables were all correlated significantly each other. (3) The results of stepwise multiple regression analysis showed that the factors influencing rehabilitation motivation were family social support, medical personnel's social support and the level of military life adaption. Conclusions: The rehabilitation motivation of hospitalized soldiers may be improved by receiving supports from family members and medical personnels and by adapting to military life. Military medical workers need to explore nursing strategies that help hospitalized orthopedic patients increase their own rehabilitation motivation.

2-Stage Detection and Classification Network for Kiosk User Analysis (디스플레이형 자판기 사용자 분석을 위한 이중 단계 검출 및 분류 망)

  • Seo, Ji-Won;Kim, Mi-Kyung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.26 no.5
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    • pp.668-674
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    • 2022
  • Machine learning techniques using visual data have high usability in fields of industry and service such as scene recognition, fault detection, security and user analysis. Among these, user analysis through the videos from CCTV is one of the practical way of using vision data. Also, many studies about lightweight artificial neural network have been published to increase high usability for mobile and embedded environment so far. In this study, we propose the network combining the object detection and classification for mobile graphic processing unit. This network detects pedestrian and face, classifies age and gender from detected face. Proposed network is constructed based on MobileNet, YOLOv2 and skip connection. Both detection and classification models are trained individually and combined as 2-stage structure. Also, attention mechanism is used to improve detection and classification ability. Nvidia Jetson Nano is used to run and evaluate the proposed system.

A Quantitative Approach to Minimize Energy Consumption in Cloud Data Centres using VM Consolidation Algorithm

  • M. Hema;S. KanagaSubaRaja
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.17 no.2
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    • pp.312-334
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    • 2023
  • In large-scale computing, cloud computing plays an important role by sharing globally-distributed resources. The evolution of cloud has taken place in the development of data centers and numerous servers across the globe. But the cloud information centers incur huge operational costs, consume high electricity and emit tons of dioxides. It is possible for the cloud suppliers to leverage their resources and decrease the consumption of energy through various methods such as dynamic consolidation of Virtual Machines (VMs), by keeping idle nodes in sleep mode and mistreatment of live migration. But the performance may get affected in case of harsh consolidation of VMs. So, it is a desired trait to have associate degree energy-performance exchange without compromising the quality of service while at the same time reducing the power consumption. This research article details a number of novel algorithms that dynamically consolidate the VMs in cloud information centers. The primary objective of the study is to leverage the computing resources to its best and reduce the energy consumption way behind the Service Level Agreement (SLA)drawbacks relevant to CPU load, RAM capacity and information measure. The proposed VM consolidation Algorithm (PVMCA) is contained of four algorithms: over loaded host detection algorithm, VM selection algorithm, VM placement algorithm, and under loading host detection algorithm. PVMCA is dynamic because it uses dynamic thresholds instead of static thresholds values, which makes it suggestion for real, unpredictable workloads common in cloud data centers. Also, the Algorithms are adaptive because it inevitably adjusts its behavior based on the studies of historical data of host resource utilization for any application with diverse workload patterns. Finally, the proposed algorithm is online because the algorithms are achieved run time and make an action in response to each request. The proposed algorithms' efficiency was validated through different simulations of extensive nature. The output analysis depicts the projected algorithms scaled back the energy consumption up to some considerable level besides ensuring proper SLA. On the basis of the project algorithms, the energy consumption got reduced by 22% while there was an improvement observed in SLA up to 80% compared to other benchmark algorithms.

Decomposition of Employment Growth in Korean Metropolitan Labor Markets: An Application of a Four-way Multifactor Partitioning (국내 7대 특·광역시 노동시장의 고용성장 요인분해 - 네 변인 다요인분해분석의 적용 -)

  • Jihan Park;Donghyn Kim
    • Journal of the Korean Regional Science Association
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    • v.39 no.4
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    • pp.53-71
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    • 2023
  • This study aims to identify the contribution of factors to employment growth over the past 20 years (1996-2016) for seven metropolitan areas in Korea. For this purpose, we performed a multifactor partitioning (MFP) analysis based on the business survey data provided by Statistics Korea. The key findings of the analysis are as follows. First, over the long run, the region effect is dominant in metropolitan employment growth, followed by the industry mix effect. On the other hand, the dynamic MFP findings suggests that future regional employment disparities are likely to be explained by industry structure. Second, the gender mix and decent job mix effect do not significantly contribute to regional employment growth. However, the contributions of individual factors are not invalid, and it is possible to infer a pattern of declining employment for men-permanent workers and increasing employment for women-contingent workers. These results indicate the importance and necessity of employment policies that can promote structural transition in regional industries and qualitative growth accompanied by employment stability.

Effect of Ingestion of Guarana on the Change in Blood Energy Substrate During Exercise for a Long Time (과라나 섭취가 장시간 운동 시 혈중 에너지 기질 변화에 미치는 영향)

  • Nam, Sang-Nam;Lee, Kyeo-Ra
    • Journal of Digital Convergence
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    • v.12 no.12
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    • pp.581-588
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    • 2014
  • The purpose of this study aims guarana ingestion to possibly be Ergogenic Aids(EA) for elite male athletes who do long time exercises. Participators who play long distance belong to H-university. They are measured HRmax by polar and treadmill, and they do run on the treadmill for 60 minutes with HRmax 70%. Participators ingest 200ml guarana and water for 5 times. They were drawn blood for 3 time such as before 30 minutes, after finish, and after 30 minutes later. Data processing was repeated of the measuring, two way repeated ANOVA, according to guarana ingestion, water ingestion, and treatment time. The result of this study identifies that guarana ingestion is more positive effect with glucose, Free fatty acid, and lactic acid than water. Hence, guarana ingestion is including function of EA to increase reserving energy on the body for rising kinetic ability.

The Development Device of the Local Food Industry - Focusing on Local Food CEOs in Daejeon.Chungnam Province - (향토음식 산업의 발전 방안 - 대전.충청지역 향토음식경영주를 중심으로 -)

  • Kim, Keun-Jong
    • Culinary science and hospitality research
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    • v.16 no.1
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    • pp.78-91
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    • 2010
  • This study aims to find a way of developing the local food industry by examining CEOs who run local food restaurants. As a result of researching the local food of Daejeon and the Chungnam province, there were 106 kinds of local food. However, all the CEOs of local food restaurants were having difficulty in operating. In order to survey the local food restaurants for development devices, 450 copies of the questionnaire were distributed to man- or woman-CEOs who operate a local food restaurant in Daejeon city and the Chungnam province. Among 450 copies of the distributed questionnaire, 390 copies were collected for this study. It used a total of 370 copies as the effective samples for an empirical analysis except 20 copies with false entries among them. The result of the empirical analysis showed as follows: 1) For the recognition of the local food, there was not difference between males and females. 2) For the factor of success on the local food restaurants, both males and females answered food taste was most important. 3) For the reason why chain business of the local food restaurants was difficult, both males and females answered there were too many side dishes coming with a main dish. 4) For the way of reinforcing competitive power of the local food restaurants, most of the male respondents and all females thought there should be financial support.

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A Comparison of Physical Fitness of High School Ssirum Elite-players According to Their Weight Class (고등부 씨름선수의 체급별 기초·전문체력 비교분석)

  • Jung, Joo-Ha;Kim, Sung-Eun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.12
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    • pp.162-169
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    • 2020
  • This study was conducted from November 25 to December 4, 2019, to unmask differences in physical fitness based on the weight class of high school Ssirum elite-players. A total of 28 high school Ssirum elite-players were compared and analyzed by measuring physical factors (muscle strength/power, agility, anaerobic power, aerobic ability, flexibility, and isokinetic muscle function) by weight class. Data were analyzed using SPSS ver. 23.0. One-way ANOVA was used for comparison between groups. There was no difference by weight class in terms of grip strength, sit-ups, sergeant jump, long jump, flexibility, side step, and reaction time. Evaluation of back muscle strength revealed that the group with more than 100 kg had greater strength than lower weight categories, whereas it was lower in the sit-ups, 20 m shuttle run and the relative values anaerobic power. Considering isokinetic muscle function, no difference was observed between the groups of back muscle strength and knee joint. The results of this study indicate that amongst the high school Ssirum elite-players, there is no difference in muscle power, flexibility, agility, and anaerobic average power per body weight, isokinetic trunk strength, and knee flexion strength, when evaluated according to weight class.

A Study on How to Cope with the Abusive Call on On-demand Bonds (독립적 보증과 그 부당한 청구에 대한 대응방안 연구)

  • KIM, Seung-Hyeon
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.69
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    • pp.261-301
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    • 2016
  • Recently the abusive calls on on-demand bonds have been a critical issue among many engineering and construction companies in Korea. On-demand bond is referred to as an independent guarantee in the sense that the guarantee is independent from its underlying contract although it was issued based on such underlying contract. For this reason, the issuing bank is not required to and/or entitled to look into whether there really is a breach of underlying contract in relation to the call on demand-bonds. Due to this kind of principle of independence, the applicant has to run the risk of the on demand bond being called by the beneficiary without due grounds. Only where the call proves to be fraudulent or abusive in a very clear way, the issuing bank would not be obligated to pay the bond proceeds for the call on on-demand bonds. In order to prevent the issuing bank from paying the proceeds under the on-demand bond, the applicant usually files with its competent court an application for injunction prohibiting the beneficiary from calling against the issuing bank. However, it is in practice difficult for the applicant to prove the beneficiary's call on the bond to be fraudulent since the courts in almost all the jurisdictions of advanced countries require very strict and objective evidences such as the documents which were signed by the owner (beneficiary) or any other third party like the engineer. There is another way of preventing the beneficiary from calling on the bond, which is often utilized especially in the United Kingdom or Western European countries such as Germany. Based upon the underlying contract, the contractor which is at the same time the applicant of on-demand bond requests the court to order the owner (the beneficiary) not to call on the bond. In this case, there apparently seems to be no reason why the court should apply the strict fraud rule to determine whether to grant an injunction in that the underlying legal relationship was created based on a construction contract rather than a bond. However, in most jurisdictions except for United Kingdom and Singapore, the court also applies the strict fraud rule on the ground that the parties promised to make the on-demand bond issued under the construction contract. This kind of injunction is highly unlikely to be utilized on the international level because it is very difficult in normal situations to establish the international jurisdiction towards the beneficiary which will be usually located outside the jurisdiction of the relevant court. This kind of injunction ordering the owner not to call on the bond can be rendered by the arbitrator as well even though the arbitrator has no coercive power for the owner to follow it. Normally there would be no arbitral tribunal existing at the time of the bond being called. In this case, the emergency arbitrator which most of the international arbitration rules such as ICC, LCIA and SIAC, etc. adopt can be utilized. Finally, the contractor can block the issuing bank from paying the bond proceeds by way of a provisional attachment in case where it also has rights to claim some unpaid interim payments or damages. This is the preservative measure under civil law system, which the lawyers from common law system are not familiar with. As explained in this article, it is very difficult to block the issuing bank from paying in response to the bond call by the beneficiary even if the call has no valid ground under the underlying construction contract. Therefore, it is necessary for the applicants who are normally engineering and construction companies to be prudent to make on-demand bonds issued. They need to take into account the creditability of the project owner as well as trustworthiness of the judiciary system of the country where the owner is domiciled.

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An Empirical Study of Social Network Service (SNS) Continuance: Incorporating the Customer Value-Satisfaction-Loyalty Model into the IS Continuance Model (소셜 네트워크 서비스(SNS)의 지속이용의도에 관한 연구: IS 지속이용모델과 고객 가치-만족-충성도 모델의 통합적 접근)

  • Choi, Sujeong
    • Asia pacific journal of information systems
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    • v.23 no.4
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    • pp.1-28
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    • 2013
  • Given that smartphone-based social network services (SNS), such as KakaoStory is now being widely used as a way for people to connect and communicate with each other, this study examines key factors leading to the continued use of SNS. People have been using PC-based SNS, such as Cyworld, for years are now using smartphone-based SNS, such as KakaoStory. KakaoStory developed by KakaoTalk has rapidly grown up as the largest smartphone-based SNS in Korea as smartphone penetration increases. It is more difficult for firms to maintain their current users over time in that alternative SNSs satisfying people's new needs are constantly emerging and evolving. In this sense, one of the most challenging issues for SNS firms is how to retain their current users in the long run. However, there are few empirical studies on this issue. Applying the IS continuance model proposed by Bhattacherjee [2001], this study explores key determinants of users' smartphone-based SNS continuance intention. The model suggests that perceived usefulness and user satisfaction are the key determinants of IS continuance intention. However, the model includes only the utilitarian value that users can obtain through the use of smartphone-based SNS, by considering perceived usefulness. Therefore, the study attempts to extend the IS continuance model by considering hedonic and social values simultaneously. More specifically, we consider subjective norms as social value that are proposed by the theory of reasoned action and the theory of planned behavior. We also consider perceived enjoyment as hedonic value that is emphasized as a key factor influencing users' behavior intention and actual behavior, particularly in the context of hedonic IS use. By considering the three values in our model simultaneously, we could offer a deeper understanding of smartphone-based SNS continuance. That is, this study could offer an explanation of how each value is associated with user satisfaction and SNS continuance intention. The customer value-satisfaction-loyalty model can strengthen the assertion that smartphone-based SNS continuance intention is determined by various different types of customer values, such as utilitarian, hedonic, and social ones. Moreover, the model provides a theoretical basis for the assertion that customer values lead to increased loyalty via customer satisfaction. In this regard, we theorize that SNS continuance intention is influenced by users' various values, namely perceived usefulness, perceived enjoyment, and subjective norms, via user satisfaction. To test the proposed research model and hypotheses, we conducted a partial least squares analysis using a total of 253 data collected on the users of smartphone-based SNS (i.e., KakaoStory). The key findings are as follows: First, it has been found that SNS continuance intention considerably depends on user satisfaction. Second, user satisfaction is determined by confirmation, perceived usefulness, and perceived enjoyment. Third, concerning the effects of the three values on SNS continuance intention, only perceived enjoyment regarded as hedonic value was statistically significant. That is, perceived usefulness considered as utilitarian value and subjective norms considered as social value had no effect on SNS continuance intention. Finally, our results indicate that confirmation increases perceived usefulness, perceived enjoyment, and user satisfaction. The results reconfirm the effectiveness of IS continuance model in predicting smartphone-based SNS continuance intention. Moreover, the results demonstrate that perceived enjoyment reflecting hedonic value is the most important predictor of SNS continuance intention. Therefore, it is imperative for firms to meet SNS users' hedonic value to retain them in the long run. Meanwhile, we could not find any empirical evidence to support the assertion that subjective norms are associated with user satisfaction and SNS continuance intention. The results lead us to conclude that when users have enough direct experience in SNS use, subjective norms have no effect on SNS continuance intention. Discussions and implications of the results are provided.