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Multicentric T cell lymphosarcoma in a Jeju native boar

  • Yang, Hyoung-Seok;Kang, Sang-Chul;Jung, Ji-Youl;Roh, In-Soon;Kim, Dae-Yong;Bae, Jong-Hee;Kim, Jae-Hoon
    • Korean Journal of Veterinary Research
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    • v.47 no.2
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    • pp.187-190
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    • 2007
  • A 7-year-old Jeju native boar was requested to the Veterinary Pathology Laboratory of Cheju National University with a clinical signs of anorexia, melena, lethargy and sudden death. At necropsy, four coalescing firm masses were occupied in the abdominal cavity between ventral surface of stomach and pancreas. Individual mass was a yellowish white in color and up to 6 cm in diameter. These masses were not encapsulated and bulged from the cut surface. Liver and spleen were enlarged and pale nodules were presented in these tissues. Some yellowish white nodules up to 5 mm in diameter were scattered in kidneys. Histopathologically, lymphoblastic tumor cells were occupied in the abdominal masses, multifocal areas of liver, kidneys, and spleen. Morphologically lymphoblastic tumor cells were round to oval in shape, and medium to large in size. They had round to oval nuclei, moderate amount of eosinophilic cytoplasm, and many mitotic figures. Immunohistochemistry revealed that tumor cells were CD3-positive and $CD79{\alpha}$-negative, consistent with T-cell lineage. Based on gross, microscopic findings and immunohistochemistry, this case was diagnosed as porcine multi-centric T cell lymphosarcoma. In animals, as in human, the T-cell lymphomas are generally more aggressive than B cell types and respond less well to therapy. In our best knowledge, this is the first report for porcine T cell lymphosarcoma in Korea.

Apocrine sweat gland adenocarcinoma in a cat (고양이의 땀샘 선암종 증례)

  • Park, Min-Hyeok;Jung, Ji-Youl;Jo, Suk-Hee;Kim, Jae-Hoon;Lee, Jin-Yong;Lee, Mi-Kyung;Kim, Jae-Hoon
    • Korean Journal of Veterinary Research
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    • v.49 no.2
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    • pp.157-161
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    • 2009
  • A 11-year-old female mixed cat with subcutaneous mass around the left 5th mammary glands was presented to local animal hospital. According to history taking, the mass recurred 2 times on the same site of abdomen. After surgical excision, subcutaneous mass was referred to Pathology Department of Veterinary Medicine in the Jeju National University. Grossly, round to oval, milky yellow or pale red nodules, measuring 0.1${\sim}$1 cm in diameter, were occupied in the subcutis. Microscopically, the most neoplastic sweat glands were proliferated in the dermis and subcutis. Most tubules were lined by round to oval shaped epithelium with eosinophilic cytoplasm, hyperchromatic nuclei with high mitotic figures and severe central necrosis. The neoplastic epithelium also had periodic acid-Schiff-positive diastase-resistant cytoplasmic granules, but was negative for Perl's iron stain. Based on the gross, histopathologic and special staining, this cat was diagnosed as apocrine sweat gland adenocarcinoma. In our best knowledge, this is the first report of apocrine sweat gland adenocarcinoma around abdominal mammary gland in a cat.

The apical root canal shape according to the root canal system of premolars with single root (단근 소구치의 근관계 형태에 따른 치근단 부위의 근관 형태)

  • Park, Min-Soo;Hwang, Ho-Keel;Jo, Hyoung-Hoon
    • The Journal of the Korean dental association
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    • v.55 no.1
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    • pp.63-70
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    • 2017
  • Materials and methods: Sixty extracted premolars were assigned to three groups according to the root canal system (Weine's classification; type I, II and III) of 20 teeth each using radiographic examination. The root tip was cut horizontally 1 mm from the anatomical apex and the apical cross-section was visualized using microscope at x50 magnification and photographed. Minimum and maximum apical root canal diameter of each tooth was measured and classified into three types by canal morphology (round, oval and flattened shape). Statistical analysis was performed to compare the apical root canal diameter and morphology according to the root canal system. Results: In apical root canal morphology at cross-sectional view, the most common shape was round in type I, flat in type II, and oval in type III. In apical root canal diameters at cross-sectional view, there was a significant difference between the minimum and maximum diameter in all types (p<0.05). The maximum diameter was 0.331 mm in type I, 0.519 mm in type II, and 0.310 mm in type III. There was a significant difference among type I, III and type II (p<0.05). Conclusion: The morphology and diameter of apical root canal was different according to the root canal system. Therefore, clinicians should consider the apical file size in view of the apical root canal shape according to the root canal system.

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In Vivo and Ex Vivo Skin Reactions after Multiple Pulses of 1,064-nm, Microlens Array-type, Picosecond Laser Treatment

  • Lyu, Herin;Park, Jinyoung;Lee, Hee Chul;Lee, Sang Ju;Kim, Young Koo;Cho, Sung Bin
    • Medical Lasers
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    • v.9 no.2
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    • pp.142-149
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    • 2020
  • Background and Objectives A picosecond-domain laser treatment using a microlens array (MLA) or a diffractive optical element elicits therapeutic micro-injury zones in the skin. This study examined the patterns of tissue reactions after delivering multiple pulses of 1,064-nm, MLA-type, picosecond neodymium:yttrium-aluminum-garnet laser treatment. Materials and Methods Multiple pulses of picosecond laser treatment were delivered to ex vivo human or brown micropig skin and analyzed histopathologically. A high-speed cinematographic study was performed to visualize the multiple pulses of picosecond laser energy-induced skin reactions in in vivo human skin. Results In the ex vivo human skin, a picosecond laser treatment at a fluence of 0.3 J/cm2 over 100 non-stacking passes generated multiple lesions of thermally-initiated laser-induced optical breakdown (TI-LIOB) in the epidermis and dermis. In the ex vivo micropig skin, stacking pulses of 20, 40, 60, 80, and 100 at a fluence of 0.3 J/cm2 generated distinct round to oval zones of tissue coagulation in the mid to lower dermis. High-speed cinematography captured various patterns of twinkling, micro-spot reactions on the skin surface over 100 stacked pulses of a picosecond laser treatment. Conclusion Multiple pulses of 1,064-nm, MLA-type, picosecond laser treatment elicit marked TI-LIOB reactions in the epidermis and areas of round to oval thermal coagulation in the mid to deep dermis.

An electron microscopic study on endocrine cells in the cardiac and fundic regions of the Korean hedgehog(Erinaceus koreanus) (한국산 고슴도치 분문부와 위저부의 내분비세포에 관한 전자현미경적 연구)

  • Lee, Jae-hyun;Lee, Hyeung-sik;Lee, Nam-soo;Kim, Jong-beom
    • Korean Journal of Veterinary Research
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    • v.30 no.4
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    • pp.373-381
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    • 1990
  • Endocrine cells in the cardiac and fundic regions of the Korean hedgehog were studied ultrastructurally. Five types of endocrine cells classified as EC, ECL, $D_1$. G and A-like cells were identified in these regions. EC cells contained pleomorphic granules, 170~500nm in diameter, with high electron density and highly dense bodies in a dense matrix. ECL cells were characterized by the presence of round or oval granules, 220~450nm in diameter, with high electron density. Some granules of ECL cells showed a small amounts of contents or empty. $D_1$ cells contained round and relatively small granules, 140~400nm in diameter, with low to moderate electron density. G cells were characterized by the presence of round or oval granules, 200~400nm in diameter, with moderate electron density. Some granules of these cells showed a narrow halo between the limiting membrane and the granular matrix. A-like cells contained round granules, 170~260nm in diameter, With high electron density. The granules of these cells showed homogeneous matrix surrounded by the tight membrane.

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Composite Tumor of Adenocarcinoma and Small Cell Neuroendocrine Carcinoma of the Uterine Cervix -A Case Report- (자궁 경부의 선암과 혼합된 신경내분비 소세포 암종 - 1 증례 보고 -)

  • Park, Hye-Rim;Lee, Yong-Woo;Park, Young-Euy
    • The Korean Journal of Cytopathology
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    • v.1 no.1
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    • pp.111-120
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    • 1990
  • Small cell neuroendocrine carcinoma of the uterine cervix is a distinct subtype of cervical cancer that appears analogous to oat cell carcinoma and carcinoid tumors of the lung. It has been assumed to be derived from the neural crest via argyrophilic cells in the normal endocervix. We have recently encountered a case of small cell neuroendocrine carcinoma of the uterine cervix coexisting with adenocarcinoma which was argyrophil negative. A 66-year-old multiparous woman was admitted because of vaginal bleeding for 2 months. Cervicovaginal smear revealed several scattered clusters and sheets of monotonous small cells with some peripheral palisading in the background of hemorrhage and necrosis. Radical hysterectomy specimen revealed an ulcerofungating tumor on endocervical canal which was composed of two components. Major component of the tumor was made up of monomorphic population of small oval-shaped tumor cells arranged in sheets and partly in acinar structures or trabecular fashion. Other component was adenocarcinoma, endocervical well-differentiated type. Argyrophilia was present on the Grimelius stain and immunohistochemical studies revealed diffuse positivity to neuron-specific enolase and carcinoembryonic antigen. Electron microscopic examination showed clusters of small round to oval cells, which had a few well-formed desmosomes and several membrane-bound, dense-core neurosectetory granules.

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Granulosa cell tumor in a sow (돼지의 과립막세포 종양)

  • Kim, Hyeong-Seok;Kang, Sang-Chul;Jung, Ji-YouI;Kim, Hyun-Sup;Kim, Dae-Yong;Kim, Jae-Hoon
    • Korean Journal of Veterinary Research
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    • v.48 no.3
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    • pp.323-326
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    • 2008
  • A two-year-old mixed breed sow was requested to the Veterinary Pathology Laboratory of Cheju National University with a clinical signs of severe abdominal pain and sudden death. Grossly, there was severe hemorrhage in abdominal cavity. Most of internal parenchymas and subcutaneous muscle showed severe pale discoloration. Both ovaries were enlarged with oval to round protruding multilobular masses and dark red in color. And they were firm and contained multiple small cysts in their cut surface. Histopathologically, numerous neoplastic granulosa cells had spherical-to-oval, hyperchromatic nuclei and scant eosinophilic cytoplasms were distributed with follicular pattern in ovarian masses. And the typical Call-Exner bodies, distinctive microcavityies, were observed in the center of small neoplastic follicles. Based on the gross and histopathologic findings, this case was diagnosed as granulosa cell tumor. In our best knowledge, this is believed to be the first report of granulosa cell tumor in a sow in Korea.

New Record of Two Apokeronopsis Species (Ciliophora: Urostylida: Pseudokeronopsidae) from Korea

  • Jung, Jae-Ho;Baek, Ye-Seul;Min, Gi-Sik
    • Animal Systematics, Evolution and Diversity
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    • v.27 no.2
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    • pp.115-122
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    • 2011
  • The morphology of the two marine hypotrichous ciliates Apokeronopsis bergeri and A. ovalis, isolated from the Yellow Sea, Korea, are described based on live and protargol-impregnated specimens. It is the first time that these species have been recorded in Korea. In addition, the small subunit ribosomal RNA gene was sequenced for comparison with the public database. The genus Apokeronopsis has recently been established in the family Pseudokeronopsidae, and the two congeners of the Korean population share the following characteristics: one row of one or more buccal cirri; usually two frontoterminal cirri; midventral complex composed of two distinctly separated rows; one left and one right marginal row; number of transverse cirri, more than eight; absence of caudal cirri; two types of cortical granules. Apokeronopsis bergeri differs from A. ovalis primarily in body shape (fusiform vs. oval form), size (usually $260{\times}80{\mu}m$ vs. $160{\times}55{\mu}m$), type II cortical granules (oval vs. round shape; yellow-green vs. mostly colourless and only a few yellow-green in colour), and morphometric data (75-106 vs. 53-70 in adoral membranelles; 37-47 vs. 24-36 in frontal cirri; 9-15 vs. 1-2 in buccal cirri), as well as molecular data (2.87% of pairwise distance).

Study on torso body types of adult males over 178cm tall (178cm 이상의 키 큰 성인남성에 대한 체간부 체형 유형화 연구)

  • Kim, Min-jung
    • The Research Journal of the Costume Culture
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    • v.30 no.5
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    • pp.675-688
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    • 2022
  • The purpose of this study is to analyze the body type characteristics of tall adult men aged 20 to 69 years to present base material on body dimensions for men's clothing companies. The research method comprised statistical analysis of 3D measurements after selecting items from the 8th Korean human body size survey related to the torso body types of 495 adult men who were at least 178cm tall. As a result, six factors were extracted, and the total explanatory variable of the entire factor was shown to be 80.499%. As a result of cluster analysis using this as an independent variable, three types were derived: Type 1, "a normal body type with an oval cross-sectional shape" (37.6%), with a larger vertical size and an oval chest cross-sectional shape compared to other types; Type 2: a "cylindrical thick body shape" (31.1%), which is the first stage of BMI obesity, with narrow shoulders and a cylindrical shape with a round cross-section; Type 3, "a body shape with broad shoulders and developed chest parts" (31.3%), with a horizontal size similar to Type 2 above the waist, but similar to Type 1 below. The results of this study are expected to be used as a basis for a clothing dimension system and clothing development for tall men reflecting the characteristics of the torso.

The Ultrastructure of the Gastro-endocrine Cells in the Gastric Mucosa of the Frog, Rana rugosa (옴개구리 Rana rugosa 위점막의 위장관 내분비세포에 관한 전자현미경적 연구)

  • 이형식;이재현
    • The Korean Journal of Zoology
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    • v.33 no.1
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    • pp.22-27
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    • 1990
  • The gastro-endocrine cells were examined in the fundic region of stomach of the frog, Rana rugosa, by transmission electron microscope. In the present paper, at least three kinds of cell type distributed in this region were idendfted according to their morphological charactedstics based on the size, shape and electron density of the secretory granules. Type I cells were characterized by the presence of round or oval granules (300-5OOnm in diameter) with high electron density. The granules showed a wide lucent between the contents and the limiting membrane. This cell was reminiscent of the ECL cell in the human alimentary mucosa. Type II cells were characterized by the presence of spherical or oval granules (11O-230nm in diameter) with low or high electron density. The granules showed a clear halo between the homogenous contents and the limiting membrane. This cell was reminiscent of the G cell in the human alimentary mucosa. Type Ill cells were characterized by the presence of elongated oval or pheomorphic granules (50-2OOnm in diameter) with low or moderate electron density and abundant microfilament bundles in the cytoplasm. The granules contained a very thin halo.

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