• 한국의상디자인학회지
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• 제13권3호
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• pp.31-43
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• 2011

This study investigates the differences in the purchasing behavior of infant & children's wear with the features of children and consumers. This study conducted a survey on female buyers of infant & children's wear. 558 questionnaires were analyzed by using SPSS 18.0 statistic program with factor analysis, Cronbach's ${\alpha}$, cluster analysis, ANOVA, and paired t-test. The results are as follows: 1. The buyer's value was identified with 3 factors: mental achievement value, social achievement value, and pleasure value. Three types of group by values were identified: group seeking mental social achievement, group seeking social achievement, and group seeking pleasure. 2. Fashion and conformity, pleasure pursuit, and reasonable price pursuit orientations showed significant differences among the value groups. 3. A significant difference was found in the imitation of wearing role models according to sibling relationships.

• Biomolecules & Therapeutics
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• 제17권1호
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• pp.12-16
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• 2009

One of the WHSC1/MMSET/NSD2 variant RE-IIBP is a histone H3-K27 methyltransferase with transcriptional repression activity. Overexpression of RE-IIBP in various types of leukemia suggests it's role in leukemogenesis. Here we identify two proteins, KRAB zinc finger protein ZNF 350 and enolase-1 as RE-IIBP interacting proteins by yeast two-hybrid screening and confirmed direct interaction in vivo and in vitro. Both proteins have been known for their role in transcriptional repression. Reporter assays using transient transfection demonstrated that both ZNF 350 and enolase-1 proteins synergistically repressed transcription with RE-IIBP, respectively. These results indicate both proteins have roles in RE-IIBP mediated transcriptional repression by involving co-repressor complex.

• 음성과학
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• 제10권4호
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• pp.93-103
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• 2003

This study examines the high-low pitch range differences between Korean and native English speakers' utterances of 36 English sentences, and explores the role of the pitch fluctuation range in the pronunciation assessment. Findings are: i) Korean speakers implement half as much pitch fluctuation as the native speakers with the achievement rate of, on an average, 47%. Especially, pitch fluctuation range is below the average in the sentence types of exclamation, yes-no & wh-questions, ii) the reason why Korean speakers' pitch fluctuation range is only half the range of the native speakers is that Korean speakers do not raise the pitch at certain sentence positions so much as the native speakers, and iii) the range of pitch fluctuation plays an important role in distinguishing the utterances of the native speakers from those of Korean speakers, but does not in rating the English utterances among Korean speakers.

• Genomics & Informatics
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• 제13권2호
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• pp.26-30
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• 2015

nc886 (=vtRNA2-1, pre-miR-886, or CBL3) is a newly identified non-coding RNA (ncRNA) that represses the activity of protein kinase R (PKR). nc886 is transcribed by RNA polymerase III (Pol III) and is intriguingly the first case of a Pol III gene whose expression is silenced by CpG DNA hypermethylation in several types of cancer. PKR is a sensor protein that recognizes evading viruses and induces apoptosis to eliminate infected cells. Like viral infection, nc886 silencing activates PKR and induces apoptosis. Thus, the significance of the nc886:PKR pathway in cancer is to sense and eliminate pre-malignant cells, which is analogous to PKR's role in cellular innate immunity. Beyond this tumor sensing role, nc886 plays a putative tumor suppressor role as supported by experimental evidence. Collectively, nc886 provides a novel example how epigenetic silencing of a ncRNA contributes to tumorigenesis by controlling the activity of its protein ligand.

• 한국기록관리학회지
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• 제22권4호
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• pp.197-203
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• 2022

이 글은 근현대기록물을 수집하고 있는 기관들을 대상으로 수집된 기록물의 유형을 살펴보고 기록관의 역할과 범위, 그리고 나아가야 할 방향에 대해 살펴보고자 쓰였다. 수집된 기록물을 대상으로 근현대기록물의 범위를 지정하고 기록관의 역할을 살펴봄으로써 기록물의 수집과 보존에 대한 균형을 이룰 수 있는 방법에 대해 고민하고 전문적인 역량을 키울수 있는 방안에 대해 제안하고자 한다.

• BMB Reports
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• 제57권3호
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• pp.135-142
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• 2024

DNA methylation is one of the most extensively studied epigenetic regulatory mechanisms, known to play crucial roles in various organisms. It has been implicated in the regulation of gene expression and chromatin changes, ranging from global alterations during cell state transitions to locus-specific modifications. 5-hydroxymethylcytosine (5hmC) is produced by a major oxidation, from 5-methylcytosine (5mC), catalyzed by the ten-eleven translocation (TET) enzymes, and is gradually being recognized for its significant role in genome regulation. With the development of state-of-the-art experimental techniques, it has become possible to detect and distinguish 5mC and 5hmC at base resolution. Various techniques have evolved, encompassing chemical and enzymatic approaches, as well as third-generation sequencing techniques. These advancements have paved the way for a thorough exploration of the role of 5hmC across a diverse array of cell types, from embryonic stem cells (ESCs) to various differentiated cells. This review aims to comprehensively report on recent techniques and discuss the emerging roles of 5hmC.

• 한국콘텐츠학회논문지
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• 제13권7호
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• pp.62-69
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• 2013

TV드라마의 여성상에 변화가 감지되었던 2005년을 기준으로 멜로장르 TV드라마에 등장하는 남성 주인공의 변화상을 알아보기 위해 1992년부터 2012년까지 시청률 상위에 위치한 멜로드라마 74편의 남성 주인공의 변화를 분석하였다. 그 결과 2005년 이후 남성 주인공의 남성상 유형의 변화는 유의미하게 나타났다. 구체적으로 변화한 유목은 첫째, 남자 주인공의 연령은 30대 이상이 증가하였다. 둘째, 미혼 남성이 증가하였다. 셋째, 여성을 남성과 동등하게 보거나 여성과 남성의 역할구분을 두지 않는 남성상이 증가하였다. 넷째, 자신의 몸을 치장하는 남성상이 증가하였다. 다섯째, 문제 발생 시 타인을 의존하는 남성상이 증가하였다. 여섯째, 타인과의 관계에서 수동적 남성상이 증가하였다. 남성의 직업과 경제적 수준, 성격과 성의식에는 변화가 없었다. 이는 2005년 이후 선행연구에서 보여 지던 남성상에 대한 고정관념이 많은 부분 사라졌으며 현재의 남성상은 보다 양성화된 형태로 나타나고 있음을 보여주는 연구 결과이다.

• International Journal of Advanced Culture Technology
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• 제8권1호
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• pp.44-55
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• 2020

The degree of mutual understanding between nursing students and instructors regarding simulation-based education remains unknown. The purpose of this study was to identify the subjectivity of nursing students and instructors about simulation-based learning, and was intended to expand the mutual understand by employing the co-orientation model. Q-methodology was used to identify the perspectives of 46 nursing students and 38 instructors. Perception types found among students in relation to simulation-based learning were developmental training seekers, instructor-dependent seekers, and learning achievement seekers. The instructors estimated the student perception types as passive and dependent, positive commitment, demanding role as facilitators, and psychological burden. Perception types found among instructors included nursing capacity enhancement seekers, self-reflection seekers, and reality seekers. The students classified the instructors' perception types as nursing competency seekers, learning reinforcement seekers, and debriefing-oriented seekers. As a result of the analysis of these relations in the co-orientation model, instructors identified psychological burden and passive and dependent cognitive frameworks among students; however, these were not reported in the students' perspectives. Likewise, the reality seekers type found among the perception types of instructors was not identified by the students. These findings can help develop and implement simulation-based curricula aimed at maximizing the learning effect of nursing students.

• The Journal of Asian Finance, Economics and Business
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• 제6권4호
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• pp.171-177
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• 2019

This study aims to investigate the effect of eating-out types on the acceptance intention of artificial seasoning when consumers eat out at restaurants. Eating-out types considered to be typical when customers visit restaurants, such as the food-exploratory type, health-oriented type, and convenience-seeking type, were studied. Based on the research of previous studies, three eating-out types were selected for the study, which were "food-exploratory", "convenience-seeking", "health-oriented". This study was conducted by AMOS 22.0 with 300 questionnaires, and the Structural Equation Model (SEM) was used for examining the hypotheses as statistical method in this study. As a result, eating-out types such as "food-exploratory" and "convenience-seeking" were found to significantly affect the acceptance intention of artificial seasoning. However, consumers' acceptance intention of artificial seasoning differed depending on their consumption value. The path coefficients from food-exploratory type and health-oriented type to acceptance intention were more significant in the hedonic-oriented group than the utilitarian-oriented group. The results of this study suggest eating-out types relate to acceptance intention of artificial seasoning and provide meaningful implications for consumers' psychological consumption value when they consider artificial seasoning.

• Child Health Nursing Research
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• 제15권2호
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• pp.127-135
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• 2009

Purpose: This cross-sectional study was designed to identify anger-expression types in late school-age children and to investigate the relation of anger and the anger-expression type to their eating disorders. Method: Two hundred fifty four children in elementary school were recruited from 14 to 25, April, 2008. The data were analyzed by using descriptive statistics, cluster analysis, t-test, ANOVA, and Tukey's multiple comparison test. Result: Three anger-expression types in late school-age children were found; Anger-in/out, Anger-control, and Low anger-expression types. Children frequently using the anger-out/in type among the three types and with a higher trait anger reported higher eating disorders. Particularly trait anger and unhealthy anger expression type were linked to eating disorders. Conclusion: This study suggests that a specific anger management program needs to be developed for late school-age children with high trait anger and frequently using the anger out/in expression type and Anger-control type than low anger-expression types. Further research needs to be done with large samples and discussed in terms of the role of gender in eating disorders.